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Logo Storyboard Document Project Name: Company Basic Training Course Name: Basic Cardiovascular Therapy and Company Cardiovascular Products Content Solutions Date: 11/15/2010 Created by: Rick Gregory Reviewed & Approved by: Reviewer Logo Table of Contents Content Solutions Date: 11/15/2010 1.1 Welcome 1.2 Introduction 1.3 Course Goals and Objectives 1.4 Course Details 2.1 Module 1 Introduction 2.2 Module Objectives 2.3 Types and prevalence of Cardiovascular Disease 2.4 Risk Factors for Cardiovascular Disease 2.5 Cardiovascular Circulation 2.6 Coronary and Endovascular Disease 2.7 Coronary Disease 2.8 Structural Heart Defects 2.9 Endovascular Disease 2.10 Diagnosis of Cardiovascular Disease 2.11 Treatment of Cardiovascular Disease 2.12 Module 1 Summary Created by: Rick Gregory Reviewed & Approved by: Reviewer Logo Course Name: Basic Cardiovascular Therapy and Product Overview Topic Name: Introduction 1.1 Welcome Objective: Launch/Start the course. Page # 1 Audio Script Word Count: 48 Onscreen text Welcome to Basic Cardiovascular Therapy and Company Cardiovascular Products Basic Cardiovascular Therapy and Company Cardiovascular Products This is an audio-driven course. Please keep the audio switched on to optimize your learning experience. This is an audio-driven course. Please keep the audio switched on to optimize your learning experience. You can click the Help button at any time to access information on the navigational features in the module. Click Help at any time for navigation features. Click Next to continue. Content Solutions Date: 11/15/2010 Filename: <Code>_##_P## Interactivity Type: Nil Animation / Interactivity Display the course name Basic Cardiovascular Therapy and Company Cardiovascular Products Overview as animated text along with the Company logo. On transition, the screen moves into the course introduction. Highlight Next button Created by: Rick Gregory Reviewed & Approved by: Reviewer Logo Course Name: Basic Cardiovascular Therapy and Product Overview Topic Name: Introduction 1.2 Introduction Objective: Introduce the course to the learner. Page # 2 Audio Script Word Count: 86 Onscreen text Filename: <Code>_##_P## Interactivity Type: Nil Animation / Interactivity This course consists of two modules. Module 1 will help you develop a fundamental understanding of cardiovascular disease and its treatment. Module two will introduce you to Company’s products and help you understand why we make vascular devices and what they mean to our patients. Dissolve to photo of doctor in discussion with patient The course will help you identify basic coronary and peripheral vascular anatomy and recognize signs and symptoms associated with coronary and peripheral vascular disease. It will also help you understand how Company products are used in the treatment of these diseases Dissolve to illustration of the circulatory system Dissolve to photo of Company’s products Dissolve to photo of cath lab On transition, the screen moves to the course objectives Content Solutions Date: 11/15/2010 Created by: Rick Gregory Reviewed & Approved by: Reviewer Logo Course Name: Basic Cardiovascular Therapy and Product Overview Topic Name: Goals and Objectives 1.3 Course Goals and Objectives Objective: List the course goals and objectives. Page # 3 Audio Script Word Count: 98 Onscreen text Filename: <Code>_##_P## Interactivity Type: Nil Animation / Interactivity This is a basic course on the fundamentals of cardiovascular disease and diagnosis, and the Company products that are used to treat it. It is appropriate and recommended for a broad range of Company employees in various roles in different areas of the company. Fade up to photo of doctor in conversation with patient The course uses photographs, illustrations, animation and interactive activities to assist you in learning. Dissolve to collage of photos and illustrations from the course Dissolve to photo of Company manufacturing facility Fade under and super titles as called by narrator to build a list of objectives After successfully completing the course, you will be able to: After successfully completing the course, you will be able to: • Identify basic Coronary and Peripheral Vascular Anatomy • Identify basic Coronary and Peripheral Vascular Anatomy • Recognize signs and symptoms associated with coronary and peripheral vascular disease • Recognize signs and symptoms associated with coronary and peripheral vascular disease • Understand how Company products are used in the treatment of these diseases • Understand how Company products are used in the treatment of these diseases Content Solutions Date: 11/15/2010 Created by: Rick Gregory Reviewed & Approved by: Reviewer Logo Course Name: Basic Cardiovascular Therapy and Product Overview Topic Name: Course Details 1.4 Course Details Objective: Explain the course details. Page # 4 Audio Script Word Count: 124 Onscreen text Filename: <Code>_##_P## Interactivity Type: Nil Animation / Interactivity Let’s briefly look at the course details. This course will take you about two hours to complete. The modules may be completed separately. The course is divided into two modules and each module contains multiple lessons. Show the picture of the face of a clock to depict time. Course Æ Module Æ Lesson Show a flowchart depicting the course structure and also highlight the relevant parts of this structure, in sync with the audio. Dissolve to illustration of heart Important concepts are explained with detailed discussions of the topic supported by photographs, animation, graphics, and interactivities. At the end of each lesson, an interactive knowledge check will help you gauge your understanding of the concepts covered. You will have to complete a scored assessment at the end of the course with a score of 80 percent or higher. You may review the course material and take the test as many times as necessary to achieve a successful score. For a walkthrough of the course interface, click Help. Content Solutions Date: 11/15/2010 • • • • • Photos Illustrations Animation Graphics Interactivities Fade under and build list as called by narrator Drop titles and build new list as called by narrator Assessment: • Passing score = 80 percent or higher • Unlimited course review • Unlimited testing For a walkthrough of the course interface, click Help. Highlight the Help button in the interface Created by: Rick Gregory Reviewed & Approved by: Reviewer Logo Module Name: Basic Cardiovascular Disease and Therapy Topic Name: Introduction 2.1 Module Introduction Objective: Introduce the module to the learner. Page # 5 Audio Script Word Count: 64 Onscreen text Filename: <Code>_##_P## Interactivity Type: Nil Animation / Interactivity Fade up to medium shot of cath lab. Module One is an introduction to the basics of cardiovascular disease and therapy. It explains the types of cardiovascular disease and its prevalence in the U.S. and around the world. It explores the heart and the vascular anatomy, the risk factors for cardiovascular disease, tools for diagnosing cardiovascular disease, and gives an overview of the medical, percutaneous and surgical therapies used to treat it. Content Solutions Date: 11/15/2010 • • • • • • Types of cardiovascular disease Prevalence in U.S. and worldwide Heart and vascular anatomy Risk factors Diagnosis Treatment Fade under and super titles as called Drop titles Created by: Rick Gregory Reviewed & Approved by: Reviewer Logo Module Name: Basic Cardiovascular Disease and Therapy Topic Name: Module Objectives 2.2 Module Objectives Objective: List the module objectives. Page # 6 Audio Script Word Count: 61 Onscreen text After successfully completing this module, you will be able to: After successfully completing this module, you will be able to: • Discuss the types and prevalence of cardiovascular disease • Recognize the risk factors for cardiovascular disease cardiovascular disease • Recognize the risk factors for cardiovascular disease • Explain cardiovascular circulation • Describe the vascular disease process • Describe the vascular disease process • Define coronary disease and how it manifests • Define coronary disease and how it manifests • Define endovascular disease and how it • Define endovascular disease and how it • Review the tests used to diagnose cardiovascular disease • Discuss the treatment of cardiovascular disease Content Solutions Date: 11/15/2010 Build bulleted list as called by narrator • Discuss the types and prevalence of • Explain cardiovascular circulation manifests Filename: <Code>_##_P## Interactivity Type: Nil Animation / Interactivity manifests • Review the tests used to diagnose cardiovascular disease • Discuss the treatment of cardiovascular disease Highlight Next to continue. Created by: Rick Gregory Reviewed & Approved by: Reviewer Logo Module Name: Basic Cardiovascular Disease and Therapy Lesson Name: Types and Prevalence of Cardiovascular Disease 2.3 Types and Prevalence of Cardiovascular Disease Objective: Explain the types and prevalence of cardiovascular disease Page #7 Word Count: 137 Audio Script Onscreen text Filename: <Code>_##_P## Interactivity Type: Nil Animation / Interactivity Fade up to angiograms of carotid, coronary, abdominal and iliac arteries Cardiovascular disease, or CVD, is a class of diseases affecting the heart and blood vessels. It includes Coronary Artery Disease, or CAD, and Peripheral Vascular Disease, or PVD. Peripheral vascular disease is also known as peripheral artery disease, or PAD CVD CAD Cardiovascular Disease Coronary Artery Disease PVD Peripheral Vascular Disease (Also known as Peripheral Artery Disease or PAD) Super titles as called. Dissolve to photo or illustration of atherosclerotic artery Coronary artery disease is the result of the accumulation and swelling of cholesterol, fat, calcium and fibrous tissues in plaques within the walls of the arteries that supply the heart with oxygen and nutrients. It is the number one killer of 1 men and women in the United States. The death rate is higher for men, especially between the ages of 35 and 55. After age 55, the death rate declines for men but continues to climb for women. After age 70 to 75, the death rate for women is higher than for 2 men of the same age. Content Solutions Date: 11/15/2010 Dissolve to photo of middle aged man Dissolve to photo of older women Created by: Rick Gregory Reviewed & Approved by: Reviewer Logo Module Name: Basic Cardiovascular Disease and Therapy Lesson Name: Types and Prevalence of Cardiovascular Disease 2.3 Types and Prevalence of Cardiovascular Disease Objective: Explain the types and prevalence of cardiovascular disease Page # 8 Word Count: 168 Audio Script Onscreen text Filename: <Code>_##_P## Interactivity Type: Nil Animation / Interactivity Peripheral vascular disease is a general term that refers to all diseases caused by the obstruction of large peripheral arteries in the body, which can result from atherosclerosis, or hardening of the arteries, inflammatory processes that lead to occlusion, an embolism or a thrombus formation. Occlusion is narrowing of an artery. An embolism is an object that travels in the bloodstream and attaches at some point to cause a blockage. A thrombus is a blood clot that forms in the vessel and 3 causes a blockage. Dissolve to illustration of the peripheral arteries in a transparent body Mortality data show that cardiovascular disease was the direct cause of death in 34.3 percent of all deaths in 2006, or one of every 2.9 deaths in the United States. Among cardiovascular deaths, the most common specific cause was coronary heart disease, which affects arteries of the heart. It was responsible for over half of total cardiovascular mortality. Strokes were responsible for 17 percent of all cardiovascular deaths, and heart failure and hypertension were each responsible for 7 percent of 4 cardiovascular mortality. Dissolve to pie chart showing CVD mortality (update to values listed in narrative) Content Solutions Date: 11/15/2010 Dissolve to photo or illustration of a blood clot occluding an artery Highlight CHD when called Highlight stroke when called Highlight heart failure and hypertension when called Created by: Rick Gregory Reviewed & Approved by: Reviewer Logo Module Name: Basic Cardiovascular Disease and Therapy Lesson Name: Types and Prevalence of Cardiovascular Disease 2.3 Types and Prevalence of Cardiovascular Disease Objective: Explain the types and prevalence of cardiovascular disease Page # 9 Word Count: 88 Audio Script Onscreen text Filename: <Code>_##_P## Interactivity Type: Nil Animation / Interactivity Cardiovascular disease is also the leading cause of death worldwide. In 2004, Coronary heart disease accounted for 7.2 million deaths worldwide and stroke accounted for 5.5 million, for a total of 18 percent of worldwide mortality from disease. It accounted for more deaths than HIV, malaria and 5 tuberculosis combined. Dissolve to pie chart showing worldwide CVD mortality Peripheral vascular disease affects approximately 8 to 12 million Americans.6 It is common among older people because it often results from atherosclerosis, which becomes more common as people age. It 7 may affect 15 to 20% of people over 70. Dissolve to photo of older men and women Content Solutions Date: 11/15/2010 Highlight CHD when called Highlight Stroke when called Highlight HIV, Malaria and TB when called Created by: Rick Gregory Reviewed & Approved by: Reviewer Logo Module Name: Basic Cardiovascular Disease and Therapy Lesson Name: Types and Prevalence of Cardiovascular Disease 2.3 Types and Prevalence of Cardiovascular Disease Objective: Explain the types and prevalence of cardiovascular disease Page # 10 Word Count: 103 Audio Script Onscreen text Filename: <Code>_##_P## Interactivity Type: Drag and Drop Interactivity Animation / Interactivity Check your knowledge about cardiovascular disease This is a list of cardiovascular diseases that resulted in deaths in the US in 2006. Drag the name of a disease to the section with the percentage of deaths caused by that disease to correctly label the chart. COMPLETION FEEDBACK: That’s right. Cardiovascular disease is the number one killer of men and women in the US. Coronary heart disease was the cause of over half the total, followed by stroke, high blood pressure, heart failure and diseases of the arteries. A group of less common causes like congenital heart defects and rheumatic heart disease comprise the Other category. Coronary Heart Disease Other Stroke High Blood Pressure Heart Failure Diseases of the Arteries Create a pie chart similar to this with the percentages of deaths in the appropriate sections. and a list of the diseases to the left. Let the user drag and drop the names of the diseases to the chart. If they drag to the correct section/percent, the name snaps in place. If they drag to the incorrect section/percent, the name snaps back to the list. Allow as many tries as necessary to get all the labels correct Highlight Click to Continue Content Solutions Date: 11/15/2010 Created by: Rick Gregory Reviewed & Approved by: Reviewer Logo Module Name: Basic Cardiovascular Disease and Therapy Lesson Name: Types and Prevalence of Cardiovascular Disease 2.3 Types and Prevalence of Cardiovascular Disease Objective: Explain the types and prevalence of cardiovascular disease Page # 11 Word Count: ## Audio Script Onscreen text Filename: <Code>_##_P## Interactivity Type: Drag and Drop Interactivity Animation / Interactivity Correct Answers: Coronary Heart Disease Stroke High Blood Pressure Heart Failure Diseases of the arteries Other Content Solutions Date: 11/15/2010 51% 17% 7% 7% 4% 14% Created by: Rick Gregory Reviewed & Approved by: Reviewer Logo Module Name: Basic Cardiovascular Disease and Therapy Lesson Name: Risk Factors for Cardiovascular Disease 2.4 Risk Factors for Cardiovascular Disease Objective: Explain the risk factors for cardiovascular disease Page # 12 Word Count: 114 Audio Script Onscreen text Fade up to photo of cath lab with procedure underway Cardiovascular disease is a significant worldwide health problem. Research is providing advances in diagnosis, treatment, and the identification of risk factors that can indicate whether a person may have or may develop cardiovascular disease. The Interheart study, a standardized case-control study conducted in 52 countries, identified nine modifiable risk factors that account for over 90 percent of the risk of a first heart attack. The risk factors are consistent for both men and women across different geographic regions and ethnic groups. They are: abnormal lipid levels, cigarette smoking, high blood pressure, diabetes, abdominal obesity, lack of physical activity, low daily intake of fruits and vegetables, alcohol overconsumption, and psychosocial index, or stress and/or 8 depression. Content Solutions Date: 11/15/2010 Filename: <Code>_##_P## Interactivity Type: Nil Animation / Interactivity Modifiable Risk Factors • • • • • • • • • Abnormal lipid levels, Cigarette smoking High blood pressure Diabetes Abdominal obesity Lack of physical activity Low daily intake of fruits and vegetables Alcohol overconsumption Psychosocial index (or stress and/or depression) Dissolve to photo of person smoking cigarette Dissolve to photo of overweight individual Dissolve to outline map of the world Super titles as called Created by: Rick Gregory Reviewed & Approved by: Reviewer Logo Module Name: Basic Cardiovascular Disease and Therapy Lesson Name: Risk Factors for Cardiovascular Disease 2.4 Risk Factors for Cardiovascular Disease Objective: Explain the risk factors for cardiovascular disease Page # 13 Word Count: 179 Audio Script Onscreen text The first five risk factors are major risk factors and they account for about 80 percent of risk. Having abnormal lipid levels is a significant risk factor. Having a total cholesterol level of less than 200 is desirable, but elevated LDL levels are the primary target of therapy. Having an LDL level below 100 is optimal and the higher it rises the greater the risk. An HDL level of less than 40 is a risk factor, for but higher HDL levels actually lower your risk. 9 Dissolve to lipid panel Highlight total cholesterol level Highlight LDL cholesterol level Highlight HDL cholesterol level Dissolve to photo of individual smoking cigarette Smoking more than doubles the risk of developing CAD and having a heart attack. Secondhand smoke also seems to increase risk. 10 High blood pressure is defined as having a blood pressure reading of 140 over 90 or higher; taking a hypertensive medicine; or, having been told at least twice by a physician or health care provider that you have high blood pressure. 11 Good control of diabetes lessens the risk of some complications of diabetes. Although the results are less clear, control of diabetes may also reduce the 12 risk of CAD. Content Solutions Date: 11/15/2010 Filename: <Code>_##_P## Interactivity Type: Nil Animation / Interactivity High Blood Pressure • 140/90 mmHg • Taking hypertensive medications • Informed at least twice Dissolve to photo of blood pressure test being administered Super titles as called by narrator Dissolve to photo of individual taking blood sugar reading Created by: Rick Gregory Reviewed & Approved by: Reviewer Logo Module Name: Basic Cardiovascular Disease and Therapy Lesson Name: Risk Factors for Cardiovascular Disease 2.4 Risk Factors for Cardiovascular Disease Objective: Explain the risk factors for cardiovascular disease Page # 14 Word Count: 130 Audio Script Onscreen text Filename: <Code>_##_P## Interactivity Type: Nil Animation / Interactivity Abdominal obesity is defined as a waist circumference of 35 inches or greater in women and 13 40 inches or greater in men. Abdominal Obesity Dissolve to photo of obese man and woman Women ≥ 35 inches Men ≥ 40 inches Super titles as called by narrator Overweight and obesity are also associated with insulin resistance and metabolic syndrome. Metabolic syndrome, an emerging risk factor, is a constellation of several risk factors including low HDL, increased triglycerides, insulin resistance, hypertension and abdominal obesity. These five factors constitute a metabolic syndrome that will increase the risk of cardiovascular events. 14 Non-modifiable risk factors include being a male over the age of 45 or a female over the age of 55. A family history that includes heart disease diagnosed in a father or brother at age 55 or younger, or in a mother or sister at age 65 or younger, is also a risk 15 factor. Content Solutions Date: 11/15/2010 Metabolic Syndrome • • • • • Drop titles and build new list as called Low HDL Increased triglycerides Insulin resistance Hypertension Abdominal obesity Dissolve to photo of middle aged couple Non-Modifiable Risk Factors • • • • Male over 45 Female over 55 CHD in father or brother under 55 CHD in mother of sister under 65 Drop titles Created by: Rick Gregory Reviewed & Approved by: Reviewer Logo Module Name: Basic Cardiovascular Disease and Therapy Lesson Name: Risk Factors for Cardiovascular Disease 2.4 Risk Factors for Cardiovascular Disease Objective: Explain the risk factors for cardiovascular disease Page # 15 Word Count: 95 Audio Script Onscreen text Filename: <Code>_##_P## Interactivity Type: Nil Animation / Interactivity The lifetime risk of developing coronary heart disease after age 40 is 49 percent for men and 32 percent for women. The incidence of coronary heart disease in women lags behind men by 10 years for total CHD and by 20 yrs for more serious clinical 17 events such as heart attack and sudden death. Some families have a higher than normal genetic risk of heart attack and stroke, and African Americans are more likely to have high blood pressure than Caucasians. They tend to have strokes earlier in life and with more severe results. 17 Dissolve to photo of older couple Content Solutions Date: 11/15/2010 Dissolve to photo of African American family Created by: Rick Gregory Reviewed & Approved by: Reviewer Logo Module Name: Basic Cardiovascular Disease and Therapy Lesson Name: Risk Factors for Cardiovascular Disease 2.4 Risk Factors for Cardiovascular Disease Objective: Explain the risk factors for cardiovascular disease Page # 16 Word Count: 103 Audio Script Onscreen text There are a number of risk factors for cardiovascular disease. Some are modifiable and others are not. Select the modifiable risk factors from the list on the left and build a list of them under the heading on the right. CORRECT FEEDBACK: That’s right. You successfully identified the modifiable risk factors for cardiovascular disease. Modifiable risk factors are those that can be changed by behavioral changes or treatment. FIRST INCORRECT FEEDBACK: Not quite. Try again. SECOND INCORRECT FEEDBACK: Sorry, that’s still not correct. Try again. THIRD INCORRECT FEEDBACK: Sorry. Here’s the list of modifiable risk factors for cardiovascular disease. Remember, modifiable risk factors are those that can be changed by behavioral changes or treatment. Content Solutions Date: 11/15/2010 Abnormal lipid levels, Cigarette smoking CHD in father or brother under 55 High blood pressure Diabetes Female over 65 Abdominal obesity Rheumatic fever Lack of physical activity Male over 45 Low daily intake of fruits and vegetables Alcohol overconsumption CHD in mother of sister under 65 Genetic predisposition Psychosocial index (or stress and/or depression) Congenital heart defect Filename: <Code>_##_P## Interactivity Type: Multiple Choice Interactivity Animation / Interactivity Modifiable Risk Factors Create a screen with a list of risk factors for cardiovascular disease on the left and a header on the right for Modifiable Risk Factors. Let the user build a list from any number of the titles in the list. When they click Submit, play either the correct or incorrect feedback. Correct answers: Abnormal lipid levels, Cigarette smoking High blood pressure Diabetes Abdominal obesity Lack of physical activity Low daily intake of fruits and vegetables Alcohol overconsumption Psychosocial index (or stress and/or depression) Submit Highlight Click Next to Continuer Created by: Rick Gregory Reviewed & Approved by: Reviewer Logo Module Name: Basic Cardiovascular Disease and Therapy Lesson Name: Cardiovascular Circulation 2.5 Cardiovascular Circulation Objective: Explain Cardiovascular Circulation Page # 17 Audio Script The circulatory system is an organ system including the blood, blood vessels and the heart that passes nutrients, gases, hormones, blood cells and metabolic waste products to and from cells in the body. Blood vessels are tube shaped conduits through which blood is distributed to body tissues. They include arteries, veins and capillaries. Word Count: 161 Onscreen text Filename: <Code>_##_P## Interactivity Type: Nil Animation / Interactivity Fade up to illustration of the circulatory system in transparent body • • • Arteries Veins Capillaries Dissolve to cutaway view of blood vessel with platelets visible Super titles as called Arteries are flexible, thick walled vessels that carry blood from the heart to the rest of the body. Blood passes from the arteries into the capillaries, the smallest blood vessels, which are only one cell thick, and are so narrow they have the diameter of a single blood cell. In the capillaries, oxygen rich blood transfers nutrients to the cells and absorbs carbon dioxide and waste products for transport to the lungs and kidneys for elimination. Blood flows from the capillaries to the veins, which are thin, low pressure vessels that return blood to the heart. Many veins have valves to maintain blood flow in a 18 single direction. Content Solutions Date: 11/15/2010 Dissolve to illustration of artery Dissolve to illustration of capillary Animate arrows going into and out of capillary Dissolve to illustration of vein with valves visible Highlight valves as called Created by: Rick Gregory Reviewed & Approved by: Reviewer Logo Module Name: Basic Cardiovascular Disease and Therapy Lesson Name: Cardiovascular Circulation 2.5 Cardiovascular Circulation Objective: Explain Cardiovascular Circulation Page # 18 Audio Script Word Count: 176 Onscreen text Filename: <Code>_##_P## Interactivity Type: Nil Animation / Interactivity Dissolve to conceptual illustration showing blood flow from arteries to capillaries to veins Blood flow refers to this movement of blood through the vessels from the arteries to the capillaries and into the veins. Pressure is a measure of the force that the blood exerts against the vessel walls as it moves blood through the vessels. Blood flows in the direction of decreasing pressure from arteries, to 19 capillaries to veins. Dissolve to illustration of circulatory system in transparent body Circulation is referred to as pulmonary, systemic and coronary. Pulmonary circulation is the flow of blood from the heart to the lungs and back to the heart. Systemic circulation is the flow of blood from the heart to the rest of the tissues in the body, except to the heart. The heart has its own circulation called the coronary circulation that is the flow of blood through the tissues of the heart. 20 Pulmonary Heart to lungs to heart Super titles as called Systemic Heart to body Coronary Through heart tissues Drop titles Dissolve to CU illustration of heart - exterior The heart is a muscular pump that moves blood through the vessels. The right side of the heart collects de-oxygenated blood from the body and sends it to the lungs. The left side collects oxygenated blood from the lungs and sends it to the body. Content Solutions Date: 11/15/2010 Created by: Rick Gregory Reviewed & Approved by: Reviewer Logo Module Name: Basic Cardiovascular Disease and Therapy Lesson Name: Cardiovascular Circulation 2.5 Cardiovascular Circulation Objective: Explain Cardiovascular Circulation Page # 19 Audio Script Deoxygenated blood flows into the right atrium from the superior vena cava and the inferior vena cava. When the atrium contracts, blood travels through the tricuspid valve into the right ventricle. When the ventricle contracts, blood flows through the pulmonary valve into the pulmonary arteries and to the lungs where the blood is re-oxygenated. Word Count: 127 Onscreen text Filename: <Code>_##_P## Interactivity Type: Nil Animation / Interactivity Dissolve to cutaway view of heart similar to this example, with all parts labeled Highlight vessels, atria, ventricles and valves as called Oxygen rich blood flows back to the heart via the pulmonary veins and enters the left atrium. When the left atrium contracts, blood flows through the mitral valve into the left ventricle. When the left ventricle contracts, blood is forced through the aortic valve into the aorta and the systemic circulation. The right and left chamber activities happen simultaneously, so blood is continuously being sent 21 to the lungs or to the systemic circulation. Graphic from Radio Sai http://media.radiosai.org/Journals/Vol_04/01AUG06/amita.htm Content Solutions Date: 11/15/2010 Created by: Rick Gregory Reviewed & Approved by: Reviewer Logo Module Name: Basic Cardiovascular Disease and Therapy Lesson Name: Cardiovascular Circulation 2.5 Cardiovascular Circulation Objective: Explain Cardiovascular Circulation Page # 20 Audio Script Word Count: 44 Onscreen text Filename: <Code>_##_P## Interactivity Type: Drag and Drop Label Animation / Interactivity Check your knowledge of the anatomy of the heart and the major vessels in the circulation. Drag the names from the list to correctly label the illustration. FEEDBACK: Congratulations! You have successfully identified the parts of the heart and the major vessels of the circulation. Right Atrium Superior Vena Cava Inferior Vena Cava. Tricuspid Valve Right Ventricle Pulmonary Valves Pulmonary Arteries Pulmonary Veins Left Atrium Mitral Valve Left Ventricle Aortic Valve 2 Aorta Create an unlabeled illustration of the heart similar to this example without directional arrows. Allow user to drag labels from list to label the heart anatomy. If they drag a label to a correct location, snap the label in place. If they drag a label to an incorrect location, snap the label back to the list. Let the exercise continue until the illustration is labeled correctly, then play feedback. Content Solutions Date: 11/15/2010 Created by: Rick Gregory Reviewed & Approved by: Reviewer Logo Module Name: Basic Cardiovascular Disease and Therapy Lesson Name: Cardiovascular Circulation 2.5 Cardiovascular Circulation Objective: Explain Cardiovascular Circulation Page # 21 Audio Script Now that you have successfully identified the anatomy of the heart, check your knowledge of blood flow through the heart. Drag the names from the list to fill in the blanks and complete the description. Word Count: 48 Onscreen text 2 Aorta Mitral Valve Pulmonary Arteries Superior Vena Cava Tricuspid Valve Left Atrium Pulmonary Valves Filename: <Code>_##_P## Interactivity Type: Fill in the Blank Animation / Interactivity Right Atrium Inferior Vena Cava. Right Ventricle Pulmonary Veins Left Ventricle Aortic Valve Deoxygenated blood flows from the FEEDBACK: _______________ and _____________ into the_____________ and through the ____ Congratulations! You have successfully explained the path of blood flow through the heart. __________ into the __________ then through the _____________ into the _______________ and to the lungs where the blood is re-oxygenated. Oxygen rich blood flows back to the heart via the _________________ into the _________________ and through the ________________ into the _________________, then through the _________________ into the __________ and the systemic circulation. Content Solutions Date: 11/15/2010 Create a correctly labeled illustration of the heart similar to this example, without directional arrows. Allow the user to view the illustration while completing the exercise. Allow user to drag names into blanks to complete the flow path. If they drag a name to a correct blank, snap the name in place. If they drag a name to an incorrect blank, snap the name back to the list. Let the exercise continue until the illustration is labeled correctly, then play feedback. Highlight Click Next to Continue Created by: Rick Gregory Reviewed & Approved by: Reviewer Logo Module Name: Basic Cardiovascular Disease and Therapy Lesson Name: Cardiovascular Circulation 2.5 Cardiovascular Circulation Objective: Explain Cardiovascular Circulation Page # 22 Audio Script Word Count: 0 Onscreen text Filename: <Code>_##_P## Interactivity Type: Nil Animation / Interactivity Correct Answer: Deoxygenated blood flows from the superior vena cava and inferior vena cava into the right atrium and through the tricuspid valve into the right ventricle, then through the pulmonary valve into the pulmonary arteries and to the lungs where the blood is re-oxygenated. Oxygen rich blood flows back to the heart via the pulmonary veins into the left atrium and through the mitral valve into the left ventricle, then through the aortic valve into the aorta and the systemic circulation. Note: Superior vena cava and inferior vena cava are correct in either position. Content Solutions Date: 11/15/2010 Created by: Rick Gregory Reviewed & Approved by: Reviewer Logo Module Name: Basic Cardiovascular Disease and Therapy Lesson Name: Coronary and Endovascular Disease 2.6 Coronary and Endovascular Disease Objective: Describe the vascular disease process Page # 23 Word Count: 176 Audio Script Onscreen text Coronary and endovascular diseases are a class of diseases stemming from atherosclerosis, commonly referred to as hardening of the arteries. Structural heart defects occur rarely and most often are not problematic, but cardiovascular disease can make them more prominent over time. Atherosclerosis is a slow progressive disease of the human vasculature in which fatty material is deposited in the vessel wall causing a narrowing, or stenosis, and eventual impairment of blood flow. The process is of unknown origin and could start in childhood. It progresses rapidly in the 30’s and usually becomes threatening when subjects reach their 50s or 60s. Deposits in the vessels are lesions called athheromas or atherosclerotic plaques and they can be focal, occurring in a specific area of the vessel, or diffuse, affecting a large portion of the vessel throughout its length. If a lesion contains calcium, it indicates the later stages of atherosclerosis. Calcified lesions cause the vessel to stiffen and become inflexible. Over time, the plaque may progress to the point that it completely occludes 22 blood flow through the vessel. Content Solutions Date: 11/15/2010 Filename: <Code>_##_P## Interactivity Type: Nil Animation / Interactivity Fade up to cutaway view of artery Animate gradual atherosclerosis building to occlude the vessel Dissolve to CU of photo or illustration of focal atheromatic lesion Dissolve to photo or illustration of diffuse atheromatic lesion Dissolve to photo or illustration of blocked vessel Created by: Rick Gregory Reviewed & Approved by: Reviewer Logo Module Name: Basic Cardiovascular Disease and Therapy Lesson Name: Coronary and Endovascular Disease 2.6 Coronary and Endovascular Disease Objective: Describe the vascular disease process Page # 24 Word Count: 153 Audio Script Onscreen text Filename: <Code>_##_P## Interactivity Type: Nil Animation / Interactivity When plaques grow into the opening of an artery and cause it to narrow, the tissues supplied by the 23 artery may not receive enough blood and oxygen. And as the diameter of the vessel gets smaller, the blood pressure will get higher as blood flows through the narrower opening and causes hypertension. Only about 50 percent of people affected by hypertension experience any physical symptoms and it is often referred to as the silent killer. 24 Dissolve to cutaway view of artery The lesions can rupture and expose the material inside to the blood stream and trigger clot formation, or thrombus, which can suddenly block all blood flow through the artery. This is the main cause of heart attack or stroke. Sometimes the clots break off, travel to other parts of the body, and block an artery in a new location. Pieces of the plaque can also break off and travel in the bloodstream to block an artery elsewhere. 25 Content Solutions Date: 11/15/2010 Animate the artery slowly occluding Animate arrows against the vessel wall to show higher pressure Dissolve to CU of illustration atheromatic lesion Animate rupture and clot formation Created by: Rick Gregory Reviewed & Approved by: Reviewer Logo Module Name: Basic Cardiovascular Disease and Therapy Lesson Name: Coronary and Endovascular Disease 2.6 Coronary and Endovascular Disease Objective: Describe the vascular disease process Page # 25 Word Count: 105 Audio Script Onscreen text Filename: <Code>_##_P## Interactivity Type: Nil Animation / Interactivity Coronary disease refers to disease in the arteries of the heart. Endovascular disease refers to disease in arteries outside the heart including the carotid arteries, upper extremity arteries, abdominal arteries, pelvic arteries and lower extremity arteries. The aortic arch is a part of the aorta, the largest blood vessel in the body. It is connected to the heart and has branches which send blood to the head, 26 neck and arms. Illustration of circulatory system in transparent body Highlight heart as called Highlight arteries as called Fade under and build list of titles as called Global vascular disease includes coronary heart disease, cerebrovascular disease, renal artery stenosis and peripheral artery disease. All of these diseases have similar risk factors and similar pathophysiology. All lead to ischemic manifestations and adverse outcomes. 27 Content Solutions Date: 11/15/2010 Global Vascular Disease • Coronary Heart Disease • Cerebrovascular Disease • Renal Artery Stenosis • Peripheral Artery Disease CHD CBVD RAS PAD Created by: Rick Gregory Reviewed & Approved by: Reviewer Logo Module Name: Basic Cardiovascular Disease and Therapy Lesson Name: Coronary and Endovascular Disease 2.6 Coronary and Endovascular Disease Objective: Describe the vascular disease process Page # 26 Word Count: 84 Audio Script Onscreen text Check your knowledge of coronary and endovascular disease with these true false questions. Correct Feedback: That’s right. Atherosclerosis causes a gradual narrowing and hardening of the arteries. Filename: <Code>_##_P## Interactivity Type: True / False Animation / Interactivity Create a true false interactivity with feedback reinforcement of topics in the lesson. Coronary and endovascular diseases are a class of diseases stemming from atherosclerosis. True Correct answer is True False Incorrect Feedback: Coronary and endovascular diseases do stem from atherosclerosis which causes a gradual narrowing and hardening of the arteries Correct Feedback: That’s correct. Atherosclerotic plaques can occur in a specific area or affect a large part of the vessel throughout its length. Atherosclerotic plaques always occur at a specific point in the vessel. True Correct answer is False False Incorrect Feedback: Actually, atherosclerotic plaques can occur in a specific area or affect a large part of the vessel throughout its length. Content Solutions Date: 11/15/2010 Created by: Rick Gregory Reviewed & Approved by: Reviewer Logo Module Name: Basic Cardiovascular Disease and Therapy Lesson Name: Coronary and Endovascular Disease 2.6 Coronary and Endovascular Disease Objective: Describe the vascular disease process Page # 27 Word Count: 80 Audio Script Onscreen text Filename: <Code>_##_P## Interactivity Type: True / False Animation / Interactivity Correct Feedback: That’s right. Only about 50 percent of people affected by hypertension experience any physical symptoms. Correct answer is False High blood pressure has symptoms that are immediately evident and easily diagnosed. True False Incorrect Feedback: Actually, only about 50 percent of people affected by hypertension experience any physical symptoms Correct Feedback: That’s correct. Lesions can rupture and trigger clot formation, or thrombus, which can suddenly block all blood flow through the artery and cause a heart attack. The most common cause of heart attack is a blood clot caused by a ruptured lesion. True Correct answer is True False Incorrect Feedback: Actually, lesions can rupture and trigger clot formation, or thrombus, which can suddenly block all blood flow through the artery and cause a heart attack. Content Solutions Date: 11/15/2010 Created by: Rick Gregory Reviewed & Approved by: Reviewer Logo Module Name: Basic Cardiovascular Disease and Therapy Lesson Name: Coronary and Endovascular Disease 2.6 Coronary and Endovascular Disease Objective: Describe the vascular disease process Page # 28 Word Count: 45 Audio Script Onscreen text Filename: <Code>_##_P## Interactivity Type: True / False Animation / Interactivity Correct Feedback: That’s correct. Endovascular disease refers to disease in arteries outside the heart. Coronary disease refers to disease in the arteries of the heart. Correct answer is False Endovascular disease is disease in arteries anywhere in the body including the heart. True False Incorrect Feedback: Actually, endovascular disease refers to disease in arteries outside the heart. Coronary disease refers to disease in the arteries of the heart. Highlight Click Next to Continue Content Solutions Date: 11/15/2010 Created by: Rick Gregory Reviewed & Approved by: Reviewer Logo Module Name: Basic Cardiovascular Disease and Therapy Lesson Name: Coronary Disease 2.7 Coronary Disease Objective: Explain coronary disease and how it manifests Page # 29 Word Count: 151 Audio Script Onscreen text Filename: <Code>_##_P## Interactivity Type: Nil Animation / Interactivity Coronary disease is a class of diseases that affect the heart. The heart is divided into two halves 28 separated by the septum, a thick muscular wall. Heart tissue is primarily muscle tissue and the wall of the left ventricle is thicker due to the greater ejection force needed to pump blood into the 29 systemic circulation. Fade up to illustration of heart showing muscle tissue The ascending aorta arises from the left ventricle of the heart and arches up and backward. The descending aorta extends down through the thorax and the diaphragm into the abdomen. 30 Five critical vessels arise from the aortic arch, including the right and left coronary arteries which are the blood supply source for coronary circulation, the brachiocephalic (or inominate) artery, the left carotid artery and the left subclavian artery. The brachiocephalic artery gives rise to the right subclavian and carotid arteries. These are the key vessels for the head, neck and upper trunk 31 circulation. Dissolve to CU of aorta anatomy (create more realistic version of this graphic) Highlight septum when called Highlight left ventricle when called Highlight each vessel as called, including ascending and descending aorta and aortic arch Content Solutions Date: 11/15/2010 Created by: Rick Gregory Reviewed & Approved by: Reviewer Logo Module Name: Basic Cardiovascular Disease and Therapy Lesson Name: Coronary Disease 2.7 Coronary Disease Objective: Explain coronary disease and how it manifests Page # 30 Word Count: 179 Audio Script Onscreen text Filename: <Code>_##_P## Interactivity Type: Nil Animation / Interactivity Dissolve to illustration of coronary arteries Coronary artery disease is a condition in which blood flow to the heart muscle is partially or completely blocked. The arteries of the cardiac circulation provide oxygen rich blood to the heart. The right coronary artery and the left coronary artery branch off the aorta as it leaves the heart to deliver oxygen-rich blood to the heart muscle. These two arteries branch into other arteries, including the circumflex artery, the marginal artery and the left anterior descending artery, that also supply blood to the heart. The coronary arteries can become partially or totally blocked by atherosclerotic plaque 32 that can result in chest pain or heart attack. Angina is pain in the chest that occurs when the demand for oxygen is greater than the available supply of oxygen to the heart. Stable angina occurs upon exertion and subsides after resting. It is related to situations where the body undergoes physical stress and it is predictable. When the patient exerts himself, he will experience pain. Unstable angina is pre-infarction angina and is less predictable. It can even occur at rest. 33 Dissolve to illustration of blocked artery Stable Angina Occurs with exertion Predictable Unstable Angina Pre-infarction angina Less predictable Dissolve to photo of individual suffering angina attack Super titles as called Content Solutions Date: 11/15/2010 Created by: Rick Gregory Reviewed & Approved by: Reviewer Logo Module Name: Basic Cardiovascular Disease and Therapy Lesson Name: Coronary Disease 2.7 Coronary Disease Objective: Explain coronary disease and how it manifests Page # 31 Word Count: 149 Audio Script Onscreen text Filename: <Code>_##_P## Interactivity Type: Nil Animation / Interactivity Prinzmetal’s angina, also known as variant angina, is a relatively rare syndrome that typically presents as angina at rest that occurs in cycles. It is caused by a vasospasm, a narrowing of the coronary arteries caused by contraction of smooth muscle tissue in the vessel walls rather than by 34 atherosclerosis directly. Dissolve to cutaway view of artery Animate vasospasm Dissolve to photo of individual exhibiting chest pain Symptoms of Angina include pressure, heaviness, tightening, squeezing, and aching across the chest, particularly behind the breastbone. These symptoms can be accompanied by indigestion, heartburn, weakness, sweating, nausea, cramping, and shortness of breath. 35 Myocardial infarction, or heart attack, is caused by a blocked artery which prevents blood flow to the muscle. The heart muscle starves for oxygen and the cells die. Typically, a clot forms in a coronary artery that has become narrowed because of atherosclerosis. Sometimes, the plaque ruptures and triggers a blood clot to form. Sudden overwhelming stress may also trigger a heart 36 attack. Content Solutions Date: 11/15/2010 • • • • • Pressure Heaviness Tightening Squeezing Aching across chest, behind breastbone • • • • Sweating Nausea Cramping Shortness of breath Super titles as called in side by side lists Dissolve to cutaway illustration of artery Animate thrombus formation until artery is completely closed Created by: Rick Gregory Reviewed & Approved by: Reviewer Logo Module Name: Basic Cardiovascular Disease and Therapy Lesson Name: Coronary Disease 2.7 Coronary Disease Objective: Explain coronary disease and how it manifests Page # 32 Word Count: 117 Audio Script Onscreen text Congestive Heart Failure is a condition in which the heart's function as a pump to deliver oxygen rich blood to the body is inadequate to meet the body's needs. It can be caused by diseases that weaken the heart muscle, like myocardial infarction and infections like myocarditis, an infection of the heart muscle. It can also be caused by diseases that cause stiffening of the heart muscles including prolonged hypertension, hemochromatosis, an iron overload in the body that is hereditary, and amyloidosis, abnormal deposits of the amyloid protein in the body. Diseases like hyperthyroidism that increase oxygen demand by the body tissue beyond the capability of the heart to deliver can also 37 lead to congestive heart failure. Content Solutions Date: 11/15/2010 Filename: <Code>_##_P## Interactivity Type: Nil Animation / Interactivity Dissolve to photo of patient in hospital bed • • • • • • Myocardial infarction Myocarditis Hypertension Hemochromatosis An amyloidosis Hyperthyroidism Super titles as called Created by: Rick Gregory Reviewed & Approved by: Reviewer Logo Module Name: Basic Cardiovascular Disease and Therapy Lesson Name: Coronary Disease 2.7 Coronary Disease Objective: Explain coronary disease and how it manifests Page # 33 Word Count: 26 Audio Script Onscreen text Check your knowledge of the major arteries. Drag the name of each artery to correctly label the illustration. Feedback: Congratulations! You have successfully identified the major arteries Ascending aorta Aortic arch Descending aorta Right coronary artery Left coronary artery Brachiocephalic artery Left carotid artery Left Subclavian artery. Right Subclavian artery Right carotid artery Filename: <Code>_##_P## Interactivity Type: Drag and Drop Label Animation / Interactivity Create an unlabeled illustration of the major arteries used in the earlier discussion. Allow the user to drag the names of the vessels to the illustration to name each vessel. If they drag a label to a correct location, let it snap in place. If they drag to an incorrect location, let it snap back to the list. Allow as many tries as necessary to correctly label the vessels. Illustration from University of Texas Health Science Center http://surgery.uthscsa.edu/patients/cardiac/ascending.asp Content Solutions Date: 11/15/2010 Created by: Rick Gregory Reviewed & Approved by: Reviewer Logo Module Name: Basic Cardiovascular Disease and Therapy Lesson Name: Coronary Disease 2.7 Coronary Disease Objective: Explain coronary disease and how it manifests Page # 34 Word Count: 27 Audio Script Onscreen text Filename: <Code>_##_P## Interactivity Type: Drag and Drop Label Animation / Interactivity Now check your knowledge of the coronary arteries. Drag the name of each artery to correctly label the illustration. Create an unlabeled illustration of the coronary arteries used in the earlier discussion. Allow the user to drag the names of the vessels to the illustration to name each vessel. If they drag a label to a correct location, let it snap in place. If they drag to an incorrect location, let it snap back to the list. Allow as many tries as necessary to correctly label the vessels. Aorta Right coronary artery Left coronary artery Left anterior descending artery Marginal artery Feedback: Congratulations! You have successfully identified the coronary arteries This and the illustrations on page 30 are from the Merck Manual and should be used only as a guide Content Solutions Date: 11/15/2010 Created by: Rick Gregory Reviewed & Approved by: Reviewer Logo Module Name: Basic Cardiovascular Disease and Therapy Lesson Name: Structural Heart Defects 2.8 Structural Heart Defects Objective: Explain structural heart Defects Page # 35 Audio Script Filename: <Code>_##_P## Interactivity Type: Nil Animation / Interactivity Word Count: 108 Onscreen text Fade up to cutaway view of heart with left and right atria, ventricles and septum labeled Rarely, holes in the heart may exist even though the heart appears to function normally. Such holes are of importance to the interventionalist, because other diseases can make these structural defects or malformations to the heart, more prominent over time. Highlight septum when called The heart has two sides separated by an inner wall called the septum, which prevents the mixing of blood. However, some babies are born with holes in the upper septum which separates the right atrium from the left atrium, and mixing of oxygen rich and oxygen-poor blood occurs. A hole in the septum between the heart’s two upper chambers is called an atrial septal defect or ASD. Most people with ASDs have no symptoms and are not aware that they have the condition. Dissolve to illustration of ASD Atrial-septal defect ASD Example only – this image is copyrighted Content Solutions Date: 11/15/2010 Created by: Rick Gregory Reviewed & Approved by: Reviewer Logo Module Name: Basic Cardiovascular Disease and Therapy Lesson Name: Structural Heart Defects 2.8 Structural Heart Defects Objective: Explain structural heart Defects Page # 36 Audio Script Filename: <Code>_##_P## Interactivity Type: Nil Animation / Interactivity Word Count: 137 Onscreen text Dissolve to illustration of PFO Patent foramen ovale, or PFO, is a tiny opening in the septum of the heart left over from prenatal development. During fetal development, the foramen ovale is usually present and it normally closes after birth. The condition usually has little or no consequence in an otherwise healthy child or adult. Indeed, up to 25percent of people are born with a PFO, but only a fraction of these individuals will have medical problems as a result. Patent Foramen Ovale PFO Dissolve to illustration showing heart valves When disease affects the valves in the heart, they may no longer work properly to maintain the correct one-way blood flow in and out of the heart. A problem with the functioning of any of the four valves is generally termed valve dysfunction. The two types of such problems that can disrupt blood flow though the valves are called regurgitation and stenosis. Sample images only Content Solutions Date: 11/15/2010 Created by: Rick Gregory Reviewed & Approved by: Reviewer Logo Module Name: Basic Cardiovascular Disease and Therapy Lesson Name: Structural Heart Defects 2.8 Structural Heart Defects Objective: Explain structural heart Defects Page # 37 Audio Script Regurgitation occurs when a valve does not close properly and blood leaks backward instead of moving in the proper one-way flow. The heart tries to make up for this by working harder, but over time, the heart will become enlarged, or dilated, and less able to pump blood through the body. Word Count: 135 Onscreen text Filename: <Code>_##_P## Interactivity Type: Nil Animation / Interactivity Dissolve to illustration showing stenosis and regurgitation. Highlight as called Stenosis occurs when the valves do not open adequately and only a small amount of blood can flow through the valve. Because of the narrowed valve, the heart must work harder to move blood through the body. If present, atrial septal defects and patent foramen ovale exist from birth. They only cause problems that require treatment if the holes are significant. A small ASD or PFO can become a significant malformation as a consequence of other diseases that change the heart’s volume or size. Content Solutions Date: 11/15/2010 Dissolve to photo of physician examining adult Created by: Rick Gregory Reviewed & Approved by: Reviewer Logo Module Name: Basic Cardiovascular Disease and Therapy Lesson Name: Structural Heart Defects 2.8 Structural Heart Defects Objective: Explain structural heart Defects Page # 38 Audio Script Word Count: 107 Onscreen text Heart valve dysfunction found in younger patients is usually due to a genetic defect in the prenatal development of the heart. In older patients, a chronic disease process is typically responsible for having defective valves. Problems with the heart valves, like regurgitation and valve stenosis, usually occur as a consequence of other heart diseases, such as Coronary Artery Disease or other disease processes that affect the volume or size of the heart. Sometimes, the valve dysfunction results from a triggering event many years earlier, such as rheumatic fever. Bacterial infection, viral infection and inflammation of valves over time can also trigger changes in valve structure and function. Content Solutions Date: 11/15/2010 Filename: <Code>_##_P## Interactivity Type: Nil Animation / Interactivity Dissolve to photo of patient receiving echocardiogram Super titles as called Rheumatic fever Bacterial infection Viral infection Valve inflammation Created by: Rick Gregory Reviewed & Approved by: Reviewer Logo Module Name: Basic Cardiovascular Disease and Therapy Lesson Name: Structural Heart Defects 2.8 Structural Heart Defects Objective: Explain structural heart Defects Page # 39 Audio Script Word Count: 68 Onscreen text Filename: <Code>_##_P## Interactivity Type: True / False Interaction Animation / Interactivity Check your knowledge of structural heart defects with these true – false questions Correct Feedback: That’s right. Patent foramen ovale is a normal condition during fetal development; ASD is not. Incorrect Feedback: Actually, patent foramen ovale is a normal condition during fetal development; ASD is not. Correct Feedback: That’s correct. Most people don’t have symptoms and aren’t aware they have the condition. Incorrect Feedback: Sorry. Most people don’t have symptoms and aren’t aware they have the condition. Content Solutions Date: 11/15/2010 Atrial-septal defect is normal in fetal development and is only a defect if it does not close after birth. True False Most people with ASD or PFO have no symptoms and may not be aware they have the condition. True The correct answer is False The correct answer is True False Created by: Rick Gregory Reviewed & Approved by: Reviewer Logo Module Name: Basic Cardiovascular Disease and Therapy Lesson Name: Structural Heart Defects 2.8 Structural Heart Defects Objective: Explain structural heart Defects Page # 40 Audio Script Word Count: 64 Onscreen text Correct Feedback: That’s right. Up to 25 percent of people are born with PFO and most have no medical problems. As many as 25 percent of people are born with PFO but few have medical problems as a result. Incorrect Feedback: Actually, Up to 25 percent of people are born with PFO and most have no medical problems. Correct Feedback: That’s right. Regurgitation occurs when a valve does not close properly and blood leaks backward. Incorrect Feedback: Sorry. Regurgitation occurs when a valve does not close properly and blood leaks backward. Content Solutions Date: 11/15/2010 True The correct answer is True False Stenosis occurs when a valve does not close properly and blood leaks backward. True Filename: <Code>_##_P## Interactivity Type: Nil Animation / Interactivity The correct answer is False False Created by: Rick Gregory Reviewed & Approved by: Reviewer Logo Module Name: Basic Cardiovascular Disease and Therapy Lesson Name: Structural Heart Defects 2.8 Structural Heart Defects Objective: Explain structural heart Defects Page # 41 Audio Script Word Count: 29 Onscreen text Correct Feedback: That’s correct. Heart valve dysfunction in younger patients is usually due to a genetic defect. Heart valve dysfunction in younger patients is usually due to a genetic defect. Incorrect Feedback: Actually, Heart valve dysfunction in younger patients is usually due to a genetic defect. Content Solutions Date: 11/15/2010 True Filename: <Code>_##_P## Interactivity Type: Nil Animation / Interactivity The correct answer is True False Created by: Rick Gregory Reviewed & Approved by: Reviewer Logo Module Name: Basic Cardiovascular Disease and Therapy Lesson Name: Endovascular Disease 2.9 Endovascular Disease Objective: Explain endovascular disease and how it manifests Page # 42 Word Count: 119 Audio Script Onscreen text Filename: <Code>_##_P## Interactivity Type: Nil Animation / Interactivity Endovascular disease is vascular disease that occurs anywhere in the body other than in the heart. It is also called Peripheral Vascular Disease and Peripheral Artery Disease. PVD can affect any vessel in the body; however, it is most common in large arteries in the peripheral arterial system. Fade up to illustration of the peripheral anatomy similar to this example but labeled per the narrative/onscreen text The most common arteries affected by PVD include the carotid arteries which supply blood to the head; the subclavian arteries which supply blood to the arms; the aorta in the mid-section of the body; the renal artery which supplies blood to the kidneys; the common iliac arteries which supply blood to the pelvis and lower limbs; and the femoral, popliteal and peroneal arteries which supply blood to the legs 38 and feet. Carotid Subclavian Aorta Renal Common Femoral Popliteal Peroneal Arteries Highlight and label the vessels as called and add arrows from labels to arteries Drop Titles Content Solutions Date: 11/15/2010 Created by: Rick Gregory Reviewed & Approved by: Reviewer Logo Module Name: Basic Cardiovascular Disease and Therapy Lesson Name: Endovascular Disease 2.9 Endovascular Disease Objective: Explain endovascular disease and how it manifests Page # 43 Word Count: 175 Audio Script Onscreen text Filename: <Code>_##_P## Interactivity Type: Nil Animation / Interactivity If a person has PVD in one area, they are more likely to have it in other areas as well. Bifurcations, or points where the arteries fork into separate vessels, are very common areas for atherosclerotic occlusions, or stenoses, to occur. Bifurcations that are commonly at risk for PVD include the carotid bifurcation, the proximal internal carotid artery and the carotid bulb; the proximal renal artery and bifurcation sites in the renal artery; the aorto-iliac artery at the bifurcation; and, the superficial femoral 39 artery at the adductor canal. Highlight bifurcations as called Now let’s take a look at some of these commonly affected arteries and the effects of PVD within them. The aortic arch gives way to the common carotid artery. The common carotid artery forks, or bifurcates, into two branches, the internal and external carotid arteries. The internal carotid artery is the larger of the two branches and supplies blood to the brain and eyes. A large number of patients experience atherosclerosis in the area of the bifurcation in the vessel, between the common and 40 internal carotid arteries. Content Solutions Date: 11/15/2010 Dissolve to angiogram of carotid arteries Common Carotid Internal Carotid External Carotid Label and add arrows as called Highlight bifurcation Created by: Rick Gregory Reviewed & Approved by: Reviewer Logo Module Name: Basic Cardiovascular Disease and Therapy Lesson Name: Endovascular Disease 2.9 Endovascular Disease Objective: Explain endovascular disease and how it manifests Page # 44 Word Count: 112 Audio Script Onscreen text Filename: <Code>_##_P## Interactivity Type: Nil Animation / Interactivity A blocked carotid artery is extremely critical and can be potentially life threatening since the carotid arteries supply blood to the brain. A diseased carotid artery can cause a stroke or a trans ischemic attack, often referred to as TIA. TIA is also known as a mini-stroke. A person who experiences a trans ischemic attack is more likely to have a full stroke within one year of having a TIA than someone who 41 does not. Highlight external carotid artery Stroke has several symptoms and they vary depending on where in the brain the blockage occurs. They include one-sided weakness or paralysis, visual problems, the inability to speak or 42 understand when spoken to, or even death. Photo of physician examining brain scans Photo of individual in wheelchair or walking with cane Photo of patient in hospital bed with attending physician Content Solutions Date: 11/15/2010 Created by: Rick Gregory Reviewed & Approved by: Reviewer Logo Module Name: Basic Cardiovascular Disease and Therapy Lesson Name: Endovascular Disease 2.9 Endovascular Disease Objective: Explain endovascular disease and how it manifests Page # 45 Word Count: 183 Audio Script Onscreen text Filename: <Code>_##_P## Interactivity Type: Nil Animation / Interactivity The renal artery delivers waste products to the kidneys for elimination and renal artery stenosis, or RAS, is a common form of endovascular disease. Disease in the renal arteries can be serious and life threatening. If the kidneys don’t function properly, toxins build up and the kidneys can die. A person is likely to experience high blood pressure, causing more harm to the kidneys and the body’s entire vascular system. Eventually they may experience renal failure and need dialysis or a kidney 43 transplant. Dissolve to illustration of renal anatomy Vascular disease in the lower extremities is serious but generally not as life threatening. The large vessels of the legs are the common femoral arteries, which come from the iliac arteries in the groin area. The superficial femoral artery, or SFA, is located in the thigh and it originates from the common femoral artery. The deep femoral artery also originates at the common femoral artery and is located in the thigh. The popliteal artery extends from the superficial femoral artery and runs behind the knee The anterior and posterior tibial arteries 44 and the peroneal artery are below the knee. Dissolve to illustration of arteries in lower extremities Content Solutions Date: 11/15/2010 Highlight renal artery Dissolve to patient receiving dialysis treatment Common Femoral Iliac Superficial Femoral Deep Femoral Popliteal Anterior / Posterior Tibial Peroneal Highlight and label arteries as called and add arrow from labels to arteries Created by: Rick Gregory Reviewed & Approved by: Reviewer Logo Module Name: Basic Cardiovascular Disease and Therapy Lesson Name: Endovascular Disease 2.9 Endovascular Disease Objective: Explain endovascular disease and how it manifests Page # 46 Word Count: 80 Audio Script Onscreen text Filename: <Code>_##_P## Interactivity Type: Nil Animation / Interactivity If a person is experiencing a blocked artery in their leg, they may feel pain in their legs or calves when they walk or exercise. If the pain in the leg is relieved by rest, this is called claudication. Other symptoms that circulation is compromised include wounds that do not heal normally and feet that are blue or cool to the touch. If the disease progresses to the point that leg or foot tissue dies, an 45 amputation may be necessary. Dissolve to photo of individual walking with limp Content Solutions Date: 11/15/2010 Dissolve to close up of wounds on foot / leg Created by: Rick Gregory Reviewed & Approved by: Reviewer Logo Module Name: Basic Cardiovascular Disease and Therapy Lesson Name: Endovascular Disease 2.9 Endovascular Disease Objective: Explain endovascular disease and how it manifests Page # 47 Word Count: 26 Audio Script Onscreen text Check your knowledge of the peripheral arteries. Drag the name of each artery to correctly label the illustration. Feedback: Congratulations! You have successfully identified the peripheral arteries. Content Solutions Date: 11/15/2010 Carotid Subclavian Aorta Renal Common Femoral Popliteal Peroneal Arteries Filename: <Code>_##_P## Interactivity Type: Drag and Drop Label Animation / Interactivity Create an unlabeled illustration of the peripheral arteries used in the earlier discussion. Allow the user to drag the names of the vessels to the illustration to name each vessel. If they drag a label to a correct location, let it snap in place. If they drag to an incorrect location, let it snap back to the list. Allow as many tries as necessary to correctly label the vessels, then play feedback. Created by: Rick Gregory Reviewed & Approved by: Reviewer Logo Module Name: Basic Cardiovascular Disease and Therapy Lesson Name: Diagnosis of Cardiovascular Disease 2.9 Diagnosis of Cardiovascular Disease Objective: Explain the tests used to diagnose cardiovascular disease Page # 48 Word Count: 131 Audio Script Onscreen text Physicians use several procedures in diagnosing cardiovascular disease, including non-invasive testing, minimally invasive testing and invasive testing. Non-invasive tests are outpatient procedures that involve little patient discomfort. Minimally invasive tests require the injection of a contrast agent to enhance imaging, but are performed as outpatient procedures with minimal patient discomfort. Invasive testing requires placement of a catheter in the blood vessels and requires a hospital stay of several hours. The goal of testing is to find a definitive diagnosis in order to 46 initiate therapy. Filename: <Code>_##_P## Interactivity Type: Nil Animation / Interactivity Fade up to photo of physician and patient in exam room Non Invasive Tests Minimally Invasive Tests Invasive Tests Super titles as called Drop titles Dissolve to photo of patient entering MRI Scanner Dissolve to angiogram image Non-Invasive Tests Non-invasive testing includes the patient history and physical examination, electrocardiogram, echocardiogram, exercise stress test, ankle-brachial index and duplex ultrasound. The patient history and physical exam is performed routinely by the physician in the office and is one of the most important steps in diagnosing 47 cardiovascular disease. Content Solutions Date: 11/15/2010 • • • • • • Patient History / Physical Exam Electrocardiogram (EKG) Echocardiogram Exercise Stress Test Ankle-Brachial Index (ABI) Duplex Ultrasound Dissolve to photo of physician and patient in exam room Super titles as called Drop titles Created by: Rick Gregory Reviewed & Approved by: Reviewer Logo Module Name: Basic Cardiovascular Disease and Therapy Lesson Name: Diagnosis of Cardiovascular Disease 2.10 Diagnosis of Cardiovascular Disease Objective: Explain the tests used to diagnose cardiovascular disease Page # 49 Word Count: 148 Audio Script Onscreen text Filename: <Code>_##_P## Interactivity Type: Nil Animation / Interactivity An electrocardiogram, also referred to as EKG or ECG, is a test that measures the electrical activity of the heartbeat. With each heartbeat, an electrical impulse passes through the heart and causes the muscle to contract and pump blood from the heart. The EKG can detect an irregular heartbeat and indicate whether parts of the heart are enlarged or 48 overworked. Dissolve to patient receiving EKG An echocardiogram, also called an echo test, takes a moving picture of the heart using ultrasound. It can show the size and shape of the heart, if a section is weak or not working correctly, problems with heart valves and if a blood clot is present. 49 Dissolve to photo of patient receiving echocardiogram An exercise stress test shows if the heart’s blood supply is sufficient and if the heart rhythm is normal. The test monitors heart rate, breathing, blood pressure, electrical activity and fatigue while the patient walks on a treadmill or pedals a stationary bike. 50 Dissolve to photo of patient on treadmill getting stress test Content Solutions Date: 11/15/2010 Dissolve to CU EKG readout Created by: Rick Gregory Reviewed & Approved by: Reviewer Logo Module Name: Basic Cardiovascular Disease and Therapy Lesson Name: Diagnosis of Cardiovascular Disease 2.10 Diagnosis of Cardiovascular Disease Objective: Explain the tests used to diagnose cardiovascular disease Page # 50 Word Count: 142 Audio Script Onscreen text Filename: <Code>_##_P## Interactivity Type: Nil Animation / Interactivity In the ankle-brachial index, or ABI, test, blood pressure is taken in the arms and ankles. The systolic ankle pressure is divided by the systolic brachial pressure. The ratio is the ABI. A normal ABI ratio is one or greater. A lower reading is abnormal and indicates peripheral artery disease. Blood pressure can be taken when the patient is at rest and again after five minutes on a treadmill. A decrease in the ABI ratio after exercise indicates 51 that significant PAD is likely. Dissolve to photo of patient having blood pressure test Duplex ultrasound, also called Doppler ultrasound, uses high speed sound waves to detect the speed and direction of blood flow in the heart, movement of the heart valves, and other blood flow evaluations 52 to indicate the presence of a blockage. Dissolve to sonogram Minimally invasive testing involves injecting a contrast material and using imaging devices to examine an area of the body. Dissolve to patient with IV entering MRI scanner Content Solutions Date: 11/15/2010 Dissolve to photo of patient on treadmill Created by: Rick Gregory Reviewed & Approved by: Reviewer Logo Module Name: Basic Cardiovascular Disease and Therapy Lesson Name: Diagnosis of Cardiovascular Disease 2.10 Diagnosis of Cardiovascular Disease Objective: Explain the tests used to diagnose cardiovascular disease Page # 51 Word Count: 113 Audio Script Onscreen text Filename: <Code>_##_P## Interactivity Type: Nil Animation / Interactivity A magnetic resonance angiogram, or MRA, is a type of magnetic resonance imaging scan that uses a magnetic field and pulses of radio waves to provide pictures of blood vessels inside the body. MRA can find problems with the blood vessels that may be causing reduced blood flow since both the blood flow and the condition of the blood vessel walls can be seen. During MRA, the area of the body being examined is placed inside an MRI machine. Contrast material is often used during MRA to make blood vessels show up more clearly. The test is commonly used to look at the blood vessels that go 53 to the brain, kidneys, and legs. Dissolve to MRA scan Content Solutions Date: 11/15/2010 Dissolve to CU of MRA scan showing vessels Dissolve to patient receiving MRA scan Created by: Rick Gregory Reviewed & Approved by: Reviewer Logo Module Name: Basic Cardiovascular Disease and Therapy Lesson Name: Diagnosis of Cardiovascular Disease 2.10 Diagnosis of Cardiovascular Disease Objective: Explain the tests used to diagnose cardiovascular disease Page # 52 Word Count: 102 Audio Script Onscreen text Filename: <Code>_##_P## Interactivity Type: Nil Animation / Interactivity A cardiac perfusion scan measures the amount of blood in the heart at rest and during exercise. During the scan, a camera takes pictures of the heart after a radioactive tracer is injected. Two sets of pictures are made during the exam, one when the patient is at rest and another after the heart has been stressed, either by exercise or after administering a drug to induce stress. The test is used to determine the cause of chest pain, to find the location and amount of damage from a heart attack, or to identify CAD and make treatment plans 54 for the patient. Dissolve to photos from cardiac perfusion scan Content Solutions Date: 11/15/2010 Dissolve to photo of patient on treadmill Dissolve to photo of physician with patient in exam room Created by: Rick Gregory Reviewed & Approved by: Reviewer Logo Module Name: Basic Cardiovascular Disease and Therapy Lesson Name: Diagnosis of Cardiovascular Disease 2.10 Diagnosis of Cardiovascular Disease Objective: Explain the tests used to diagnose cardiovascular disease Page # 53 Word Count: 113 Audio Script Onscreen text Filename: <Code>_##_P## Interactivity Type: Nil Animation / Interactivity Invasive testing involves inserting a catheter into an artery to introduce a contrast material to visualize an area inside the body. Angiography is an imaging technique used to visualize the inside, or lumen, of blood vessels by injecting an x-ray contrast. A catheter about the size of a pencil lead is inserted through the skin and into the artery to deliver the contrast and an X-ray is taken of the area being examined. X-rays pass through the blood vessel, but not through the contrast, and delineate the lumen. Catheter angiography is considered the gold standard, but it is increasingly being replaced by magnetic resonance angiography and computed tomography angiography as the technology 55 improves. Dissolve to photo of cath lab with angiogram procedure underway Content Solutions Date: 11/15/2010 Dissolve to angiogram Dissolve to photo of catheter Dissolve to photo of cath lab Created by: Rick Gregory Reviewed & Approved by: Reviewer Logo Module Name: Basic Cardiovascular Disease and Therapy Lesson Name: Diagnosis of Cardiovascular Disease 2.10 Diagnosis of Cardiovascular Disease Objective: Explain the tests used to diagnose cardiovascular disease Page # 54 Word Count: 93 Audio Script Onscreen text Check your knowledge of the diagnostic tests used to diagnose cardiovascular disease. Drag the names of the tests from the list to the correct category of tests. When you have finished, click submit. CORRECT FEEDBACK: That’s correct. You have correctly identified the types of tests used to diagnose cardiovascular disease. Filename: <Code>_##_P## Interactivity Type: Drag and Drop Sort Animation / Interactivity Angiogram Patient History / Physical Exam Electrocardiogram (EKG) Magnetic Resonance Angiogram Echocardiogram Exercise Stress Test Cardiac Perfusion Scan Ankle-Brachial Index (ABI) Duplex Ultrasound Non-Invasive Minimally Invasive Create a screen with a list of diagnostic tests and a three column display with headers for each category of test. Let the user drag the test names to any category. If user makes incorrect entries, give incorrect feedback. Allow two tries to get it right and if it is incorrect on the third try, give the third incorrect feedback. Invasive FIRST INCORRECT FEEDBACK: Sorry, that’s not quite right. Try again. SECOND INCORRECT FEEDBACK: That’s a good effort, but it’s not totally correct. Try again. THIRD INCORRECT FEEDBACK: Sorry, this is the correct listing of the types of tests used to diagnose cardiovascular disease. Take a close look so you will remember. Submit Highlight Click to Continue Content Solutions Date: 11/15/2010 Created by: Rick Gregory Reviewed & Approved by: Reviewer Logo Module Name: Basic Cardiovascular Disease and Therapy Lesson Name: Treatment of Cardiovascular Disease 2.11 Treatment of Cardiovascular Disease Objective: Explain the treatment of cardiovascular disease Page # 55 Word Count: 123 Audio Script Onscreen text The first steps in treatment of cardiovascular disease are often medical therapies to alter or control risk factors that can be modified. Any patient who smokes is strongly encouraged to quit and may be provided with smoking cessation aids. Obese patients are encouraged to lose weight and reduce their waist size to below 40 inches for males and below 35 inches for females. Filename: <Code>_##_P## Interactivity Type: Nil Animation / Interactivity Fade up to photo of physician in discussion with patient Dissolve to photo of individual smoking Dissolve to photo of obese individual If the patient has high blood pressure, he may be prescribed hypertensives to lower blood pressure. If appropriate, anitplatelets like aspirin and clopidogrel may be prescribed to prevent platelets from sticking together and an anticoagulant like warfarin may be prescribed to prevent clotting. Dissolve to patient having blood pressure test If the patient has abnormal lipid levels, a statin may 56 be prescribed to lower blood cholesterol levels. Dissolve to image of lipid panel results Content Solutions Date: 11/15/2010 Created by: Rick Gregory Reviewed & Approved by: Reviewer Logo Module Name: Basic Cardiovascular Disease and Therapy Lesson Name: Treatment of Cardiovascular Disease 2.11 Treatment of Cardiovascular Disease Objective: Explain the treatment of cardiovascular disease Page # 56 Word Count: 147 Audio Script Onscreen text Filename: <Code>_##_P## Interactivity Type: Nil Animation / Interactivity Interventional therapies for cardiovascular disease are endovascular procedures that include percutaneous transluminal angioplasty, or PTA, stents, thrombolytics and atherectomy. Dissolve to photo of cath lab with procedure underway Percutaneous transluminal angioplasty is the most common non-surgical treatment for peripheral vascular disease and coronary artery disease. PTA is a procedure that dilates or opens up blocked arteries by threading a thin plastic tube called a balloon catheter to the point of narrowing. The balloon is inflated and presses the plaque against the vessel wall in order to restore proper blood flow. The balloon is then deflated and removed from the artery. In addition to compressing the plaque, it stretches the walls of the vessel and is known as a 57 controlled dissection. Stents are often placed within a vessel to act as a support structure. Stents are metal tubes that provide scaffolding to hold plaque out of the lumen, and they reduce restenosis from elastic recoil after PTA. Content Solutions Date: 11/15/2010 Interventional Therapy • Percutaneous Transluminal Angioplasty (PTA) • Stents • Thrombolytics • Atherectomy Super titles as called Dissolve to photo of angiogram procedure being performed Dissolve to image showing catheter in vessel Dissolve to animation showing balloon angioplasty Dissolve to photo / illustration of stents Created by: Rick Gregory Reviewed & Approved by: Reviewer Logo Module Name: Basic Cardiovascular Disease and Therapy Lesson Name: Treatment of Cardiovascular Disease 2.11 Treatment of Cardiovascular Disease Objective: Explain the treatment of cardiovascular disease Page # 57 Word Count: 140 Audio Script Onscreen text Filename: <Code>_##_P## Interactivity Type: Nil Animation / Interactivity Stents are designed to provide radial strength, flexibility, scaffolding and conformability, and are either balloon expandable or self expanding. Balloon expandable stents are mounted on a balloon dilatation catheter and are typically placed in protected areas like the coronary arteries. Self expandable stents deploy when they are uncovered and are typically placed in areas of motion or flexion like the carotid arteries or the superficial femoral 58 artery. Dissolve to different photo of stent Thrombolysis is a procedure to dissolve a blood clot by introducing a clot dissolving medication delivered through catheter. The drug used most commonly is tPA or tissue plasminogen activator. With continuing improvements in catheter technology, intra-arterial thrombolysis is being increasingly used as an interventional procedure for treating acute and chronic lower extremity arterial disease. Thrombolysis offer patients options for therapy when medical treatment alone is not enough and surgery may be too risky. 59 Content Solutions Date: 11/15/2010 Dissolve to photo / illustration of balloon dilation catheter Dissolve to photo / illustration of self expanding stent Dissolve to photo / Illustration of thrombolytic procedure Dissolve to photo of cath lab with procedure underway Created by: Rick Gregory Reviewed & Approved by: Reviewer Logo Module Name: Basic Cardiovascular Disease and Therapy Lesson Name: Treatment of Cardiovascular Disease 2.11 Treatment of Cardiovascular Disease Objective: Explain the treatment of cardiovascular disease Page # 58 Word Count: 91 Audio Script Onscreen text Filename: <Code>_##_P## Interactivity Type: Nil Animation / Interactivity Atherectomy is a procedure that removes plaque from the interior of a vessel using any of several devices. Rotational atherectomy uses a high speed rotation burr coated with microscopic diamond particles rotating at about 120,000 rpm. The plaque is broken into fragments smaller than red blood cells which pass harmlessly into the circulation. Dissolve to photo of rotation burr Directional atherectomy uses a small cutter at the end of the catheter. The mechanically driven cutter shaves off the plaque and stores it in a chamber at the tip. The plaque is removed when the catheter is withdrawn. Dissolve to photo / illustration of directional atherectomy device Content Solutions Date: 11/15/2010 Dissolve to photo / illustration of device in use Created by: Rick Gregory Reviewed & Approved by: Reviewer Logo Module Name: Basic Cardiovascular Disease and Therapy Lesson Name: Treatment of Cardiovascular Disease 2.11 Treatment of Cardiovascular Disease Objective: Explain the treatment of cardiovascular disease Page # 58 Word Count: 158 Audio Script Onscreen text Filename: <Code>_##_P## Interactivity Type: Nil Animation / Interactivity For patients who do not respond to medical or percutaneous treatment, surgery is the ultimate option. Bypass is still the gold standard for surgical outcomes. It is done to divert blood flow around a blockage. Bypass can be performed using the 61 patient’s own vein or by adding graft material. Dissolve to photo of OR with procedure underway Endarterectomy is the surgical removal of the plaque. The artery is opened and the plaque is dissected and removed. This leaves a wide open artery and restored flow. Although it is most commonly performed with the carotid arteries it may be done anywhere the vascular surgeon has access to the vessel. It is a highly invasive procedure and carotid stents can sometimes be used in lieu of endarterectomy. 62 Dissolve to photo / illustration of carotid endarterectomy Amputation, or the removal of a limb, is used as a last resort in extreme cases. Vascular surgeons only perform it when the circulation is severely reduced and cannot be improved by other methods 63 such as PTA, stent placement or bypass. Dissolve to photo of patient with amputated limb Content Solutions Date: 11/15/2010 Dissolve to X-ray of bypass Created by: Rick Gregory Reviewed & Approved by: Reviewer Logo Module Name: Basic Cardiovascular Disease and Therapy Lesson Name: Treatment of Cardiovascular Disease 2.11 Treatment of Cardiovascular Disease Objective: Explain the treatment of cardiovascular disease Page # 60 Word Count: 93 Audio Script Onscreen text Filename: <Code>_##_P## Interactivity Type: True / False Animation / Interactivity Check your knowledge of the treatment of cardiovascular disease with these true-false questions. Correct Feedback: That’s right. The first steps in treatment are often to lose weight, stop smoking or lower blood cholesterol. The first steps in treatment of cardiovascular disease are often medical therapies to alter or control risk factors that can be modified. Incorrect Feedback: Actually controlling modifiable risk factors is often the first step and includes attempts to help the patient lose weight, stop smoking or lower blood cholesterol. True Correct Feedback: That’s Correct. PTA does use a balloon to stretch the arterial wall and compress plaque against the artery wall. Percutaneous transluminal angioplasty is a procedure that uses a balloon to stretch the arterial wall and compress plaque against the artery wall. Incorrect Feedback: Actually, PTA does use a balloon to stretch the arterial wall and compress plaque against the artery wall. True Content Solutions Date: 11/15/2010 The correct answer is True False The correct answer is True. False Created by: Rick Gregory Reviewed & Approved by: Reviewer Logo Module Name: Basic Cardiovascular Disease and Therapy Lesson Name: Treatment of Cardiovascular Disease 2.11 Treatment of Cardiovascular Disease Objective: Explain the treatment of cardiovascular disease Page # 61 Word Count: 80 Audio Script Onscreen text Filename: <Code>_##_P## Interactivity Type: True / False Animation / Interactivity Correct Feedback: That’s right. Self expanding stents do not require a balloon for deployment but they require a catheter to deliver them to the stenosis. The correct answer is True Self expanding stents do not require a balloon catheter for deployment into a narrowed artery. True False Incorrect Feedback: Actually, self expanding stents do not require a balloon for deployment but they do require a catheter to deliver them to the stenosis. The correct answer is True Correct Feedback: That’s right. Surgery is the ultimate option if a patient does not respond to medical or percutaneous treatment. If patients do not respond to medical or percutaneous treatment, surgery is the ultimate option. Incorrect Feedback: Actually, surgery is the ultimate option if a patient does not respond to medical or percutaneous treatment. True Content Solutions Date: 11/15/2010 False Created by: Rick Gregory Reviewed & Approved by: Reviewer Logo Module Name: Basic Cardiovascular Disease and Therapy Lesson Name: Treatment of Cardiovascular Disease 2.11 Treatment of Cardiovascular Disease Objective: Explain the treatment of cardiovascular disease Page # 62 Word Count: 41 Audio Script Onscreen text Filename: <Code>_##_P## Interactivity Type: True / False Animation / Interactivity Correct Feedback: That’s right, bypass surgery uses a graft to divert blood flow around a blockage. Endarterectomy is the surgical removal of plaque. The correct answer is False Bypass surgery is the surgical removal of plaque. True False Incorrect Feedback: Sorry. Bypass surgery uses a graft to divert blood flow around a blockage. Endarterectomy is the surgical removal of plaque. Content Solutions Date: 11/15/2010 Created by: Rick Gregory Reviewed & Approved by: Reviewer Logo Module Name: Basic Cardiovascular Disease and Therapy Lesson Name: Summary 2.12 Module 1 Summary Objective: Review the module content Page # 63 Audio Script Word Count: 134 Onscreen text You have successfully completed Basic Cardiovascular Disease and Therapy, the first module in this course. Filename: <Code>_##_P## Interactivity Type: <Name> Interactivity Animation / Interactivity Fade up to illustration of the heart and circulatory system visible in transparent body Fade under and super titles as called In this module, you have learned about the types and prevalence of cardiovascular disease, the anatomy of the circulatory system and how blood flows through the body. You also learned about vascular disease process, coronary disease, structural heart defects and endovascular disease, and how they manifest and how cardiovascular disease is diagnosed and treated. • • • • • • • • • • Types of CVD Prevalence of CVD Circulatory Anatomy Blood Flow Vascular Disease Process Coronary Disease Structural Heart Defects Endovascular Disease CVD Diagnosis CVD Treatment Module 2 of this course is an overview of interventional devices and Company's portfolio of cardiovascular products. You will learn about the basic interventional procedure and the types of interventional devices used to treat cardiovascular disease. Provide links to the quiz and to the course menu You can go directly to Module 2 now, or return at a later time. To go to Module 2 now, close this window and return to Company LMS to select it. . Content Solutions Date: 11/15/2010 Created by: Rick Gregory Reviewed & Approved by: Reviewer