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Tissues and Integumentary System Tissues □ Tissues: □Group of cells similar in structure and perform a common or related function □Four basic tissue types: □Connective □Epithelial □Nervous □Muscle Tissues □ Epithelial Tissue □ General Characteristics □Cover organs and the body □Lines body cavities and hollow organs □Functions include protection, absorption, filtration, excretion and sensor reception □Avascular (contains no blood vessels) but supported by underlying connective tissue □Regeneration – can replace lost cell by mitosis Tissues □ Connective Tissue □General Characteristics □Most abundant and widely distributed □Functions include binding and support, protection, insulation and transportation of substances within the body □Types include: □Adipose, cartilage, bone, blood Bone Adipose Tissue Hyaline Cartilage Elastic Cartilage Fibrocartilage Tissues □ Nervous Tissue □General Characteristics □Found in the brain, spinal cord and nerves □Function is to transmit electrical signals □Two major types of cells □Neurons □Supporting cells Tissues □ Muscle Tissue □ General Characteristics □Highly vascularized □Responsible for most types of body movement □3 types □Skeletal muscle (attached to bones) □Cardiac muscle (heart) □Smooth muscle (walls of hollow organs) Skeletal Muscle Smooth Muscle Cardiac Muscle Covering and Lining Membranes □ Body Membranes □ Cutaneous Membrane □Skin □Is exposed to air and is a dry membrane Covering and Lining Membranes □ Mucous Membranes □ Line body cavities that open to the exterior □ “Wet” or moist membranes bathed by secretions □ Adapted for secretion and absorption Covering and Lining Membranes □ Serous Membranes □ Lines body cavities that are closed to the exterior of the body □ Occur in pairs separated by serous fluid The Integumentary System □ Composed of □Skin □Oil glands □Sweat glands □Hairs □Nails The Skin □ Skin Structure □ 2 distinct regions of skin □ Epidermis – outermost protective layer □ Dermis – tough leathery layer located underneath the epidermis □ Hypodermis □ Underneath the dermis The Skin □ The Epidermis □ Cells in the inner layer undergo rapid cell division, producing new cells that push older cells to the surface of the skin □ Older cells also begin making keratin, a tough, fibrous protein. □ When these cells die, they form a waterproof covering on the skin’s surface and protective properties. The Skin □ The Epidermis □ Cells called melanocytes are also found in the epidermis □ They are responsible for producing the pigment melanin □ Melanin absorbs UV radiation to protect the skin from sun damage □ The more melanin produced, the darker the skin color The Skin □ The Dermis □ The second or inner layer of skin □ Described as strong flexible connective tissue or as the hide because it binds the entire body together □ Richly supplied with nerves, blood vessels, sweat and oil glands □ Collagen and elastic fibers found here □ Collagen – toughness/hydration □ Elastic fibers – elasticity The Skin □ The Hypodermis □ Also called the subcutaneous layer □ Mostly made up of adipose tissue □ Anchors the skin to underlying organs and stores fat □ Acts a shock absorber and insulates deep tissues from temp. changes outside body Skin Color □ Skin Color □ Involves 3 following pigments: □ Melanin □ Amount and kind (yellow to reddish brown to black) □ Carotene □ Orange-yellow pigment □ Amount of oxygen bound to hemoglobin □ Pigment found in red blood cells Skin Color □ Cyanosis □ Blue or dark blue tint to the skin □ Could be due to heart failure and respiratory disorders due to lack of oxygen Skin Color □ Erythema □ Reddish tint to skin □Can be caused by fever, hypertension, allergies or inflammation Skin Color □ Jaundice □Yellowish tint to the skin □Can indicate a liver disorder, in which bile accumulates in the blood □ Pallor or Blanching □ “Pale” or “white” tint to skin □ Can be due to stress, low blood pressure, fear or anemia Skin Color □ Bruises □ Formed when blood escapes from circulation and clot beneath the skin □ Also called hematomas, which means blood swelling Skin Appendages □ Sudoriferous Glands □ Commonly called sweat gland □ Around 3 million of them per person and spread throughout the body Skin Appendages □ Types of Sweat Glands □ Eccrine sweat glands □ Produce sweat (mostly water, some salts, vitamin C, antibodies and wastes) □ Major purpose of sweat is to prevent body overheating □ Apocrine sweat glands □ Secretion contains materials similar to sweat along with fatty substances and proteins □ Secretion is odorless until acted on by bacteria, then it takes on a musky odor (body odor) Skin Appendages □ Sebaceous Glands □ Commonly called oil glands □ Everywhere except palms and soles □ Secrete sebum □Softens and lubricates the skin □Prevents brittle hair □Has bacterium killing action Skin Appendages □ Hair and Hair Follicles □ Importance: □ Keeps warmth □ Sensory reception □ Guards against physical trauma, heat loss and sunlight □ Filter large particles from the air we inhale Skin Appendages □ Hair Structure □ Mostly composed of dead, keratinized cells □ Chief regions are the shaft (projects from the skin) and the root (embedded in skin) □ Pigment is determined by melanocytes at the base of follicle Skin Appendages □ Hair □ Smooth muscle cells called arrector pili surround each hair follicle □ When they contract, the hair follicle is pulled upright and this dimples the skin surface □ This is how chill or goose bumps are formed Skin Imbalances □ Acne □Active inflammation of the oil glands □Usually caused by bacterial infection, especially staphylococcus □More common in adolescents and could be associated with increased hormones Skin Imbalances □ Vitiligo Skin Imbalances □ Eczema Skin Imbalances □ Skin Cancer □ Major risk factor for its development is overexposure to UV radiation in sunlight □ Three types: □ Basal Cell Carcinoma □ Squamous Cell Carcinoma □ Malignant Melanoma Skin Imbalances □ Basal Cell Carcinoma □ Least malignant and most common form □ Appear most often on sun exposed areas of the face □ Looks like shiny dome-shaped nodules that later develop a pearly beaded edge □ 99% cure rate by surgical removal Skin Imbalances □ Squamous Cell Carcinoma □ Lesion appears as a scaly reddened rounded elevation □ Commonly found on head (scalp, ears and lower lips) □ It can grow quickly and metastasize if not removed surgically Skin Imbalances □ Malignant Melanoma □ Cancer of the melanocytes and least common form but most dangerous □ Highly metastatic (rapidly to lymph and blood vessels) and resistant to chemotherapy □ Appears as a spreading brown to black patch □ Early detection is key but survival is poor if lesion is over 4 mm thick ABCD Rule □ A = Asymmetry □ Two sides of pigmented mole do not match □ B = Border irregularity □ Borders of mole are not smooth □ C = Color □ Different colors in pigmented area □ D = Diameter □ Spot is larger then 6 mm in diameter Skin Imbalances □ Burns □ Defined as tissue damage caused by intense heat, electricity, radiation, or certain chemicals □ They denature proteins and cause cell death in affected areas □ Classified as □ 1st degree □ 2nd degree □ 3rd degree Skin Imbalances □ 1st Degree Burns □ Only the epidermis is burned □ Usually not serious and heal within 2-3 days □ Sunburn Skin Imbalances □ 2nd Degree Burns □ Epidermis and top layer of the dermis is damaged □ Skin is reddened and painful with blisters Skin Imbalances □ 3rd Degree Burns □ The epidermis, dermis and often part of the hypodermis are destroyed □ Area appears graywhite or black □ Regeneration is not possible Functions of the Integumentary System Relationships Between the Integumentary System and Other Body Systems