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Chapter 21 Diet and Cancer Copyright © 2011 Delmar, Cengage Learning. ALL RIGHTS RESERVED. Objectives • Discuss how nutrition can be related to development or prevention of cancer • State effects of cancer on nutritional status of host • Describe nutritional problems resulting from medical treatment of cancer • Describe nutrient therapy for cancer clients Copyright © 2011 Delmar, Cengage Learning. ALL RIGHTS RESERVED. Cancer • Second leading cause of death in U.S. • Characterized by abnormal cell growth – Can occur in any organ • Cancerous tumors: – Malignant – Affect structure • Consequently, affect function of organs (continues) Copyright © 2011 Delmar, Cengage Learning. ALL RIGHTS RESERVED. Cancer • High mortality rate – But does not always cause death • Oncology – Study of cancer • Oncologist – Physician who specializes in cancer Copyright © 2011 Delmar, Cengage Learning. ALL RIGHTS RESERVED. Causes of Cancer • Precise etiology unknown • Contributing factors: – Heredity, viruses, environmental carcinogens, and possibly emotional stress • Not inherited – But some families appear to have genetic predisposition (continues) Copyright © 2011 Delmar, Cengage Learning. ALL RIGHTS RESERVED. Causes of Cancer • Viruses linked to cancer: – Epstein Barr • Nasopharyngeal cancer, T-cell lymphoma, Hodgkin’s disease, and gastric carcinoma – Hepatitis B • Liver cancer – Human papillomavirus (HPV) • Cervical cancer (continues) Copyright © 2011 Delmar, Cengage Learning. ALL RIGHTS RESERVED. Causes of Cancer • Environmental carcinogens – Cause cancer after repeated exposure • Radiation – X-rays, sun, and nuclear wastes • Certain chemicals ingested in food and water or touched by skin • Substances breathed in – E.g., tobacco smoke, asbestos Copyright © 2011 Delmar, Cengage Learning. ALL RIGHTS RESERVED. Classifications of Cancer • Majority fall under these headings: – – – – Carcinomas Sarcomas Lymphomas Leukemias Copyright © 2011 Delmar, Cengage Learning. ALL RIGHTS RESERVED. Skin Cancer • Becoming more prevalent • Three types: 1. Basal cell • Most common 2. Squamous cell 3. Melanoma • • Most serious Deadliest Copyright © 2011 Delmar, Cengage Learning. ALL RIGHTS RESERVED. Relationships of Food and Cancer • Certain substances in foods considered carcinogenic: – Nitrates in cured and smoked foods associated with stomach and esophagus cancer – High-fat diets associated with uterine, breast, prostate, and colon cancer (continues) Copyright © 2011 Delmar, Cengage Learning. ALL RIGHTS RESERVED. Relationships of Food and Cancer • Certain substances in foods considered carcinogenic: – Excessive caloric intake associated with gallbladder and endometrial cancer – Alcohol and cigarettes associated with lung, mouth, pharynx, and esophagus cancer (continues) Copyright © 2011 Delmar, Cengage Learning. ALL RIGHTS RESERVED. Relationships of Food and Cancer • Certain diets seem to have health benefits: – High-fiber helps protect against colorectal cancer – Vitamin C-rich may protect against stomach and esophagus cancer – Vitamin A-rich may protect against lung, bladder, and larynx cancer (continues) Copyright © 2011 Delmar, Cengage Learning. ALL RIGHTS RESERVED. Relationships of Food and Cancer • Health benefits: – Phytochemicals occur naturally in plant foods • Considered anticarcinogenic – Legumes contain vitamins, minerals, protein, and fiber • May protect against cancer – High intake of soy foods associated with decreased risk of breast and colon cancer Copyright © 2011 Delmar, Cengage Learning. ALL RIGHTS RESERVED. The Effects of Cancer • Depend on location of tumor • May cause unexplained weight loss, weakness, early satiety, and anorexia • May lead to loss of muscle tissue, hypoalbuminemia, and anemia Copyright © 2011 Delmar, Cengage Learning. ALL RIGHTS RESERVED. Treatment of Cancer • Surgical removal, radiation, chemotherapy, or combination of methods • Side effects can affect nutrition (continues) Copyright © 2011 Delmar, Cengage Learning. ALL RIGHTS RESERVED. Treatment of Cancer • Radiation and chemotherapy may cause: – Xerostomia • Dry mouth – Dysphagia • Difficulty swallowing – Anorexia – Nausea and vomiting – Diarrhea with possible fluid and electrolyte imbalances Copyright © 2011 Delmar, Cengage Learning. ALL RIGHTS RESERVED. Nutritional Care • Calorie needs greater than before illness • Clients who can eat normally tolerate side effects of therapy better • Clients can form aversions to food – Making anorexia worse • Soft diet if chewing problems (continues) Copyright © 2011 Delmar, Cengage Learning. ALL RIGHTS RESERVED. Nutritional Care • Low-residue diet for diarrhea • High-protein, high-calorie diets and plenty of fluids for clients undergoing radiation or chemotherapy • 45 to 50 calories per kg of body weight per day (continues) Copyright © 2011 Delmar, Cengage Learning. ALL RIGHTS RESERVED. Nutritional Care • Carbohydrates and fat needed to provide energy and spare protein for tissue building and immune system • 1.0 to 1.2 g of protein per kg per day • Malnourished clients may need from 1.3 to 2.0 g of protein per kg per day • Vitamins and minerals essential (continues) Copyright © 2011 Delmar, Cengage Learning. ALL RIGHTS RESERVED. Nutritional Care • Encourage foods that increase appetite: – Foods brought from home – Cold foods • May be more appealing – Milk, cheese, eggs, and fish • May be more appealing than meat – Can taste bitter (continues) Copyright © 2011 Delmar, Cengage Learning. ALL RIGHTS RESERVED. Nutritional Care • Several small meals may be better tolerated than three large meals • Control nausea and pain • Nutritional supplements may be needed Copyright © 2011 Delmar, Cengage Learning. ALL RIGHTS RESERVED. Stop and Share • Consider the following scenario: – A client with cancer feels that comments to encourage eating are depressing reminders of the cancer and her situation. How can you be helpful to her? (continues) Copyright © 2011 Delmar, Cengage Learning. ALL RIGHTS RESERVED. Stop and Share • At appropriate time, explain why eating is important • Encourage her to eat foods she enjoys • Recommend avoiding eating at time of day nausea is likely to occur • Recommend refraining from food that gives off odors that contribute to nausea Copyright © 2011 Delmar, Cengage Learning. ALL RIGHTS RESERVED. Conclusion • Cancer – Disease characterized by abnormal cell growth • Energy needs increase – Due to hypermetabolic state and tumor’s need for energy nutrients • Surgery, radiation, and chemotherapy can cause side effects that affect nutrition (continues) Copyright © 2011 Delmar, Cengage Learning. ALL RIGHTS RESERVED. Conclusion • Improving nutritional state difficult – Due to illness and anorexia • Parenteral or enteral nutrition may be necessary • Health care professional can help client improve nutrition Copyright © 2011 Delmar, Cengage Learning. ALL RIGHTS RESERVED.