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COURSE TITLE: Principles of Biomedical Science INSTRUCTOR: Mrs. Nichole Bell, RN ([email protected]) COURSE DESCRIPTION: This course provides an introduction to the biomedical sciences through exciting “hands-on” projects and problems. The students in these exciting new courses will study the human body and various health conditions. A theme through the first course is to determine the factors that led to the death of a fictional person through exciting “hands-on” projects and activities. This course is the first in a series of four in the Biomedical Sciences curriculum set forth by Project Lead the Way. These courses will provide the scientific foundation necessary for the student to succeed in any healthcare or biomedical field. I would encourage you to continue on with the PLTW curriculum in subsequent semesters where you will concentrate and go into further detail in biomedical sciences. The subsequent classes are called Human Body Systems, Medical Interventions, and Biomedical Innovations. SUPPLIES: You will need a one-inch binder with dividers, paper, and a blue or black pen in class with you every day. Textbook – None! This makes it imperative that you organize your handouts, notes, activities, and assignments in your binder. This will become your reference material. RULES: 1. Be Here! Do what you know is right! 2. Bring all classroom materials and a good attitude to class with you each day. 3. Be ready to learn when the bell rings. 4. Respect yourself, your classmates, and your school. 5. Remain in seat until the teacher dismisses you. 6. No food or drink in class. 7. No cell phone use. 8. Do Not Plagiarize! It is illegal. 9. Pull your own weight! We will be doing a lot of group work – do your part. MISSED WORK: It is up to you to arrange times for make-ups if you are absent for tests, labs, or quizzes. Make-up sessions should be scheduled for either before or after school and should be done immediately upon the students return. Students will be given advanced notice of upcoming Tests and Quizzes, therefore students are expected to be prepared to make-up the missed test or quiz immediately upon their return. A student who knows they will be absent from class on a particular date (due to sports, academic activities, etc.) is still expected to hand in any work that was assigned to be due for that day. You may hand in work the day before it is due, or the morning of, but any work handed in later than the assigned class time will be counted as late. CLASS OVERVIEW: Unit 1-Human Body Systems Unit one provides the foundation and develops the theme for the course. Students are engaged by reading about a woman who is found dead in the entry to her house. In order to determine how she died the students are introduced to seven major human body systems: cardiovascular, digestive, endocrine, immune, nervous, respiratory and urinary. Students explore the meaning of the term system and investigate the interrelatedness of human body systems. Students begin to develop effective skills in conducting internet research, documenting scientific sources, and summarizing key ideas. Unit 2-Heart Disease During unit two, students focus on the circulatory system. Students look at the role of this system in maintaining homeostasis by examining the structure and function of the heart and the engineering principles of fluid mechanics involved in pumping blood efficiently. Students are introduced to experimental design and LabVIEW software to collect and analyze heart data including: heart rate, blood pressure, and EKG. Unit 3-Diabetes In this unit students investigate the serious effects a disease within one system can have on homeostasis in the body as a whole. The disease studied is diabetes. Students are introduced to basic chemistry, the biochemistry of macromolecules, and the relationship of these molecules to metabolic function. The causes, symptoms, treatments and effects of diabetes are studied as well as the life style implications associated with this disease. The engineering principles involved in feedback loops are discussed and related to insulin and glucose. Unit 4-Sickle Cell Disease Genetics is the focus of this unit. It uses Sickle Cell Disease as a tool to gain an understanding of the inheritance of traits. Students are introduced to bio-informatics as they explore the role of genes in determining the structure and function of proteins. Students build models of DNA and the beta-globin protein as they study the structure, function, and interrelatedness of nucleic acids and proteins. To study the impact of mutations they analyze karyotypes and explore the effects of single base-pair mutations. Unit 5-Hypercholesterolemia In unit 5, students look at the function of cholesterol in the body and its role in heart disease. DNA technologies include polymerase chain reaction (PCR), restriction fragment length polymorphism (RFLP) analysis, and DNA electrophoresis are introduced as students complete activities dealing with the familial hypercholesterolemia gene. Unit 6-Infectious Diseases Bacteria and viruses, the causative agents of infectious diseases, are the focus of unit six. Structural differences between these organisms are examined as students Gram stain bacteria and produce models of virus particles. The differences in treatment protocols for bacterial and viral diseases are investigated. Students produce a public health campaign to educate peers about the dangers and the prevention of an infectious disease. Unit 7-Medical Interventions Medical interventions past and present are explored in this unit including surgery, medication, technology, and life style choice. The focus of the work is how medical interventions have changed over time to prolong and improve the quality of life. Students explore how a new pharmaceutical treatment goes from initial discovery to market, and research medical interventions currently available for common diseases or disorders including heart disease, sickle cell disease, hypercholesterolemia, and infectious diseases. The connections between engineering and biomedical sciences are introduced as students explore the design and development of various medical devices including prosthetics, artificial skin, insulin pumps, joint replacements, and heart pacemakers.