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The Fetal Period (9th-38th Week) Chronology of Human Development Day 1 - conception takes place. 7 days - blastocyst implants in mother’s uterus. 18 days - heart begins to beat. 4 weeks - eye, ear and respiratory system begin to form. 6 weeks - brain waves recorded, skeleton complete, reflexes present. 8 weeks - all body systems present. 12 weeks - weighs one ounce. 16 weeks - genital organs clearly differentiated, fetus kicks and turns 20 weeks - has hair on head, weighs one pound, 12 inches long. 23 weeks - 15% chance of viability outside of womb if birth premature. 24 weeks - 56% of babies survive premature birth. 25 weeks - 79% of babies survive premature birth. 10 week fetus Video of Embryonic Development http://www.pbs.org/wgbh/nova/miracle/program.html 10 Week Old Fetus and Placenta Development of the Placenta and Fetal Membranes Implantation of the Blastocyst (Day 7) By 8 Days, the Amniotic Cavity Appears By 9 Days, the Embryo is Completely Implanted in the Uterine Endometrium Days 10-13 of Embryonic Development Days 12-15 of Embryonic Development Formation of the Chorionic Villi Human Embryo at the Beginning of the Second Month of Development Transverse Section through a Full Term Placenta Functions of the Placenta 1.) provide nutrients and oxygen 2.) remove metabolic waste 3.) provide maternal antibodies 4.) produce steroid hormones (estrogen and progesterone) to maintain pregnant state 5.) produce HCG to support corpus luteum http://www.pbs.org/wgbh/nova/miracle/program.html 6.) produce prostaglandins which is involved in maintenance of pregnancy and onset of labor. RH Incompatibility: Erythroblastosis Fetalis Rh factors are a group of surface molecules that are present on the surface membrane of red blood cells in most individuals. Rh factors provoke a strong immune response in Rh- individuals Anti-Rh antibodies can be administered to the Rh- mother immediately after birth of each Rh+ baby. These antibodies destroy Rh+ red blood cells in her circulation before they stimulate her own immune response; this prevents her from manufacturing anti-Rh antibodies. Prenatal Screening Techniques Amniocentesis -usually between 15-18 weeks of gestation -.5% fetal loss with Amniocentesis Chorionic Villus Sampling - performed 10-12 weeks of gestation - 0.8-1.0% fetal loss with CVS Ultrasonography Transducer produces a stream of inaudible, high frequency sound waves (3.5-7.0 megahertz) that penetrate the body and bounce off organs inside. Example of Ultrasound Ultrasound can be used to determine gestational age and assess fetal size a) The Crown-rump length (CRL) This measurement can be made between 7 to 13 weeks and gives very accurate estimation of the gestational age. b) The Biparietal diameter (BPD) The diameter between the 2 sides of the head. This is measured after 13 weeks. It increases from about 2.4 cm at 13 weeks to about 9.5 cm at term. Different babies of the same weight can have different head size, therefore dating in the later part of pregnancy is generally considered unreliable. c) The Femur length (FL) Measures the longest bone in the body and reflects the longitudinal growth of the fetus. d) The Abdominal circumference (AC) The single most important measurement to make in late pregnancy. It reflects more of fetal size and weight rather than age. 2-D Versus 3-D Ultrasonography Body Changes during Pregnancy Your Changing Body 1 Month 3 Months 6 Months 9 Months Weight Gain During Pregnancy Total Weight Gain = 24-30lbs External and Internal Fetal Monitoring Approaches Fetal Monitoring Graph Fetal Heartbeat Uterine Contractions Presentation Positions 97% of all Preg. 2.5% of all Preg. <.5% of all Preg. Cesarean Section Occurs about 20-25% of the time 4 Stages of Labor Stage 1: begins with the onset of true labor contractions and lasts until the cervix is completely dilated. Stage 2: begins when the cervix is completely dilated and ends when the baby is born. Stage 3: begins after the baby is delivered and ends when the placenta is expelled. Stage 4: begins when the placenta is expelled and lasts until the woman’s medical condition is stabilized. First Stage of Labor Common Methods of Anesthesia Negotiating the Birth Canal Common Types of Episiotomies Stage 2: Delivery of Baby and Placenta Serge and Melinda are having a baby http://www.pbs.org/wgbh/nova/miracle/program.html