Download Curriculum Vitae

Curriculum Vitae
PERSONAL
Name:
Nicola Bottoni
Address:
Via De Ruggero n° 4,
42100 REGGIO EMILIA
ITALY
Date of Birth:
5th March, 1962
Telephone Nbr:
039 / 0522 / 284803
Fax:
039 / 0522 / 296288
E-mail:
[email protected]
[email protected]
EDUCATION
1976-1981:
Educated at Grammar School in Reggio Emilia (Liceo Classico L.
Ariosto), Italy.
1981-1987:
Studied Medicine and Surgery at the Faculty of the University of Parma,
Italy. Graduated cum laude in Medicine and Surgery at the same
University in 1987, presenting a thesis on “Effects of different nitrates on
vascular smooth muscle cells. Experimental study”.
1987-1991:
Attended the course of specialisation in Cardiology, University of Parma.
Presented thesis of specialisation on “Carotid Sinus Syndrome”.
Registered as a specialist in Cardiology in 1991.
TRAINING
1986-1987:
Intern scholar at the Institute of Internal Medicine, Parma University.
1988-1989:
Obtained a scholarship for the multicentric study GISSI-2 at the 1st
Cardiology Unit and Intensive Care, Arcispedale S. Maria Nuova, Reggio
Emilia.
- Attended the Laboratory of Electrophysiology directed by professor J.A. Salerno-Uriarte in
the following periods:
from 13/11/1995 to 27/12/1995 (Division of Cardiology, Policlinico S.Matteo, Pavia, Italy),
from 12/11/1996 to 28/12/1996 (Casa di cura Città di Pavia, Pavia, Italy),
from 15/10/1997 al 25/4/1998 and from 12/3/2000 to 12/4/2000 (Casa di cura Mater Domini,
Insubria University, Castellanza, Italy).
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- Attended the Laboratory of Electrophysiology of the Hopital Cardiologique du Haut-Leveque,
Bordeaux-Pessac (France), directed by professor M. Haissaguerre in the following period:
from 19/11/2001 to 01/12/2001;
from 02/11/2003 to 15/11/2003;
from 12/11/2007 to 25/11/2007.
- Attended the Laboratory of Electrophysiology of the II. Med. Abteilung, Allgemeines
Krankenhaus St Georg, Hamburg, Germany, directed by professor Karl-Heinz Kuck in the
following period:
from 15/11/2004 to 27/11/2004.
- Attended the Laboratory of Electrophysiology of the S. Raffaele Hospital, Milan, Italy,
directed by professor Carlo Pappone in the following period:
from 21/11/2005 to 26/11/2005.
- Attended the Section of Cardiac Electrophysiology at the Cleveland Clinic Heart Center,
Cleveland, Ohio, directed by doctor Andrea Natale from November 20th through December
2nd 2006.
EXPERIENCE
From December 1990 up to the current time:
Senior Registrar at the Department of Cardiology and Arrhythmologic Center, Santa Maria
Nuova Hospital, Reggio Emilia, Italy, routinely performing electrophysiologic studies, RF
catheter ablations, PM (biventricular) and ICD implants.
NUMBER OF PUBLICATIONS AND ABSTRACTS
From 1988 to 2007: 100, between national and international journals.
LIST OF SOCIETIES
Member of the A.I.A.C. (Associazione Italiana Aritmologia e Cardiostimolazione).
Member of the ANMCO (Associazione Nazionale Medici Cardiologi Ospedalieri).
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Publications
1) Salvo-D, Ferretti-PP, Versari-A, Serafini-D, Bottoni-N, Pantaloni-M, Borasi-G. Bullseye
and 3D: Comparison between two methods for the display of myocardial perfusion in the
evaluation of coronary stenosis. The Journal of Nuclear Medicine and Allied Sciences 1990;
34: 229-230.
2) Brignole-M; Menozzi-C; Lolli-G; Bottoni-N; Gaggioli-G. Long-term outcome of paced and
nonpaced patients with severe carotid sinus syndrome. Am J Cardiol 1992; 69(12): 1039-1043.
3) Brignole-M; Menozzi-C; Gianfranchi-L; Bottoni-N; Lolli-G. The clinical and prognostic
significance of the asystolic response during the head-up tilt test. Eur J Card Pacing
Electrophysiol 1992; 2(2): 109-113.
4) Brignole-M; Menozzi-C; Gianfranchi-L; Lolli-G; Bottoni-N; Oddone-D. A controlled trial
of acute and long-term medical therapy in tilt-induced neurally mediated syncope. Am J Cardiol
1992; 70(3): 339-342.
5) Brignole-M; Gianfranchi-L; Menozzi-C; Raviele-A; Oddone-D; Lolli-G; Bottoni-N. Role of
autonomic reflexes in syncope associated with paroxysmal atrial fibrillation. J Am Coll Cardiol
1993; 22(4): 1123-1129.
6) Menozzi-C; Brignole-M; Lolli-G; Bottoni-N; Oddone-D; Gianfranchi-L; Gaggioli-G.
Follow-up of asystolic episodes in patients with cardioinhibitory, neurally mediated syncope
and VVI pacemaker. Am J Cardiol 1993; 72(15): 1152-1155.
7) Gaggioli-G; Bottoni-N; Brignole-M; Menozzi-C; Lolli-G; Oddone-D; Gianfranchi-L.
Progression to second or third-degree atrioventricular block in patients electrostimulated for
bundle branch block: A long-term study. (La progressione a blocco atrioventricolare di 2° e 3°
grado nei pazienti elettrostimolati per blocco di branca e sincope: uno studio a lungo termine).
G Ital Cardiol 1994; 24(4): 409-416.
8) Gianfranchi-L, Brignole-M, Menozzi-C, Bottoni-N, Bollini-R, Lolli-G, Oddone-D,
Gaggioli-G. Sequential right-sided and left-sided radiofrequency catheter ablation of
atrioventricular conduction in patients with atrial fibrillation. Cardiostimolazione 1994; 12
(3):253-254.
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9) Menozzi-C; Brignole-M; Gianfranchi-L; Lolli-G; Oddone-D; Gaggioli-G; Bottoni-N.
Radiofrequency catheter ablation and modulation of atrioventricular conduction in patients with
atrial fibrillation. Pacing Clin Electrophysiol 1994; 17(11 II): 2143-2149.
10) Brignole-M; Gianfranchi-L; Menozzi-C; Bottoni-N; Bollini-R; Lolli-G; Oddone-D;
Gaggioli-G. A new pacemaker for paroxysmal atrial fibrillation treated with radiofrequency
ablation of the AV junction. Pacing Clin Electrophysiol 1994; 17(11 II): 1889-1894.
11) Brignole-M; Gianfranchi-L; Menozzi-C; Bottoni-N; Bollini-R; Lolli-G; Oddone-D;
Gaggioli-G. Influence of atrioventricular junction radiofrequency ablation in patients with
chronic atrial fibrillation and flutter on quality of life and cardiac performance. Am J Cardiol
1994; 74(3): 242-246.
12) Gaggioli-G; Brignole-M; Menozzi-C; Bottoni-N; Gianfranchi-L; Oddone-D; Lolli-G.
Reappraisal of the vasodepressor reflex in carotid sinus syndrome. Am J Cardiol 1995; 75(7):
518-520.
13) Menozzi-C; Brignole-M; Tomasi-C; Lolli-G; Bottoni-N; Oddone-D; Gianfranchi-L.
Carotid sinus syncope: The most frequent neurally mediated syncope in the elderly. Arch
Gerontol Geriatr 1995; 20(1): 7-14.
14) Brignole-M; Menozzi-C; Bottoni-N; Gianfranchi-L; Lolli-G; Oddone-D; Gaggioli-G.
Mechanisms of syncope caused by transient bradycardia and the diagnostic value of
electrophysiologic testing and cardiovascular reflexivity maneuvers. Am J Cardiol 1995; 76(4):
273-278.
15) Brignole-M; Menozzi-C; Gianfranchi-L; Lolli-G; Oddone-G; Gaggioli-G; Bottoni-N.
Single-session step-wise radiofrequency catheter modification of atrioventricular conduction in
patients with paroxysmal atrial fibrillation. Eur J Cardiac Pacing Electrophysiology 1995; 5(1):
18-22.
16) Gaggioli-G; Brignole-M; Menozzi-C; Oddone-D; Gianfranchi-L; Bollini-R; Bottoni-N;
Lolli-G. Rivalutazione della componente vasodepressiva nella sindrome del seno carotideo.
[The re-evaluation of the vasodepressive component in the carotid sinus syndrome]. G Ital
Cardiol 1995; 25(3): 327-33.
17) Gaggioli-G; Brignole-M; Menozzi-C; Devoto-G; Oddone-D; Gianfranchi-L; Gostoli-E;
Bottoni-N; Lolli-G. A positive response to head-up tilt testing predicts syncopal recurrence in
carotid sinus syndrome patients with permanent pacemakers. Am J Cardiol 1995; 76(10): 7202.
18) Menozzi-M, Brignole-M, Bottoni-N, Lolli-G, Oddone D, Gianfranchi-L, Gaggioli-G. La
stimolazione cardiaca nelle sincopi vasovagali. Cardiostimolazione 1995; 13: 55-58.
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19) Menozzi-C; Bottoni-N; Lolli-G; Tomasi-C. Epidemiology of syncope. Cerebrovasc Dis
1997; 7(5): 298.
20) Gaggioli-G; Bottoni-N; Mureddu-R; Foglia-Manzillo-G; Mascioli-G; Bartoli-P; Musso-G;
Menozzi-C; Brignole-M. Effects of chronic vasodilator therapy to enhance susceptibility to
vasovagal syncope during upright tilt testing. Am J Cardiol 1997; 80(8): 1092-4.
21) Brignole-M; Gaggioli-G; Menozzi-C; Gianfranchi-L; Bartoletti-A; Bottoni-N; Lolli-G;
Oddone-D; Del-Rosso-A; Pellinghelli-G. Adenosine-induced atrioventricular block in patients
with unexplained syncope: The diagnostic value of ATP testing. Circulation 1997; 96(11):
3921-3927.
22) Brignole-M; Menozzi-C; Gianfranchi-L; Musso-G; Mureddu-R; Bottoni-N; Lolli-G.
Assessment of atrioventricular junction ablation and VVIR pacemaker versus pharmacological
treatment in patients with heart failure and chronic atrial fibrillation: A randomized, controlled
study. Circulation 1998; 98(10): 953-960.
23) Brignole-M; Menozzi-C; Gaggioli-G; Musso-G; Foglia-Manzillo-G; Mascioli-G; FradellaG; Bottoni-N; Mureddu-R. Effects of long-term vasodilator therapy in patients with carotid
sinus hypersensitivity. Am Heart J 1998; 136(2): 264-268.
24) Gianfranchi-L; Brignole-M; Menozzi-C; Lolli-G; Bottoni-N. Progression of permanent
atrial fibrillation after atrioventricular junction ablation and dual-chamber pacemaker
implantation in patients with paroxysmal atrial tachyarrhythmias. Am J Cardiol 1998; 81(3):
351-354.
25)
Bottoni-N; Lolli-G; Tomasi-C; Calzolari-M; Menozzi-C. Syncope epidemiology in
athletes. Int J Sports Cardiol 1999; 8(3): 117-119.
26) Davie-A; McMurray-J; Brignole-M; Gianfranchi-L; Menozzi-C; Bottoni-N; Lolli-G.
Assessment of atrioventricular junction ablation and VVIR pacemaker versus pharmacological
treatment in patients with heart failure and chronic atrial fibrillation [1] (multiple letters).
Circulation 1999; 99(22): 2966-2967.
27) Gianfranchi-L; Brignole-M; Menozzi-C; Lolli-G; Bottoni-N. Determinants of development
of permanent atrial fibrillation and its treatment. Europace 1999; 1(1): 35-9.
28) Bartoletti-A; Gaggioli-G; Menozzi-C; Bottoni-N; Del-Rosso-A; Mureddu-R; Musso-G;
Foglia-Manzillo-G; Bonfigli-B; Brignole-M. Head-up tilt testing potentiated with oral
nitroglycerin: a randomized trial of the contribution of a drug-free phase and a nitroglycerin
phase in the diagnosis of neurally mediated syncope. Europace 1999; 1(3): 183-6.
29) Brignole-M; Menozzi-C; Del-Rosso-A; Costa-S; Gaggioli-G; Bottoni-N; Bartoli-P; SuttonR. New classification of haemodynamics of vasovagal syncope: beyond the VASIS
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classification. Analysis of the pre-syncopal phase of the tilt test without and with nitroglycerin
challenge. Vasovagal Syncope International Study. Europace 2000; 2(1): 66-76.
30) Lupi-G; Brignole-M; Oddone-D; Bollini-R; Menozzi-C; Bottoni-N.
Effects of left
ventricular pacing on cardiac performance and on quality of life in patients with drug refractory
heart failure. Am J Cardiol 2000; 86(11): 1267-1270.
31) Brignole-M; Gaggioli-G; Menozzi-C; Del-Rosso-A; Costa-S; Bartoletti-A; Bottoni-N;
Lolli-G. Clinical features of adenosine sensitive syncope and tilt induced vasovagal syncope.
Heart 2000; 83(1): 24-28.
32) Brignole-M; Menozzi-C; Moya-A; Garcia-Civera-R; Mont-L; Alvarez-M; Errazquin-F;
Beiras-J; Bottoni-N; Donateo-P. Mechanism of syncope in patients with bundle branch block
and negative electrophysiological test. Circulation 2001; 104(17): 2045-2050.
33) Bottoni-N; Donateo-P; Tomasi-C; Lolli-G; Oddone-D; Croci-F; Menozzi-C; Brignole-M.
Comparison of the clinical and electrophysiological characteristics of symptomatic concealed
and manifest accessory pathways. (Confronto delle caratteristiche cliniche ed elettrofisiologiche
dei pazienti con via accessoria atrioventricolare occulta e manifesta). Ital Heart J Supplement
2001; 2(8): 888-893.
34) Alboni-P; Brignole-M; Menozzi-C; Raviele-A; Del-Rosso-A; Dinelli-M; Solano-A;
Bottoni-N. Diagnostic value of history in patients with syncope with or without heart disease. J
Am Coll Cardiol 2001; 37(7): 1921-1928.
35) Alboni-P; Tomasi-C; Menozzi-C; Bottoni-N; Paparella-N; Fuca-G; Brignole-M; CappatoR. Efficacy and safety of out-of-hospital self-administered single-dose oral drug treatment in
the management of infrequent, well-tolerated paroxysmal supraventricular tachycardia. J Am
Coll Cardiol 2001; 37(2): 548-553.
36) Croci-F; Brignole-M; Alboni-P; Menozzi-C; Raviele-A; Del-Rosso-A; Dinelli-M; SolanoA; Bottoni-N; Donateo-P. The application of a standardized strategy of evaluation in patients
with syncope referred to three syncope units. Europace 2002; 4(4): 351-355.
37) Donateo-P; Brignole-M; Alboni-P; Menozzi-C; Raviele-A; Del-Rosso-A; Dinelli-M;
Solano-A; Bottoni-N; Croci-F. A standardized conventional evaluation of the mechanism of
syncope in patients with bundle branch block. Europace 2002; 4(4): 357-360.
38) Puggioni-E; Guiducci-V; Brignole-M; Menozzi-C; Oddone-D; Donateo-P; Croci-F;
Solano-A; Lolli-G; Tomasi-C; Bottoni-N. Results and complications of the carotid sinus
massage performed according to the "method of symptoms". Am J Cardiol 2002; 89(5): 599601.
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39) Donateo-P; Brignole-M; Menozzi-C; Bottoni-N; Alboni-P; Dinelli-M; Del-Rosso-A;
Croci-F; Oddone-D; Solano-A; Puggioni-E. Mechanism of syncope in patients with positive
adenosine triphosphate tests. J Am Coll Cardiol 2003; 41(1): 93-98.
40) Bottoni-N; Tomasi-C; Donateo-P; Lolli-G; Muia-N; Croci-F; Oddone-D; Menozzi-C;
Brignole-M. Clinical and electrophysiological characteristics in patients with atrioventricular
reentrant and atrioventricular nodal reentrant tachycardia. Europace 2003; 5(3): 225-9.
41) Bottoni-N; Menozzi-C; Brignole-M. Management of patients with recurrent neuromediated
syncope. Mediterranean-Journal-of-Pacing-and-Electrophysiology 2003; 5(2): 73-76.
42) Bottoni-N; Donateo-P; Quartieri-F; Tomasi-C; Oddone-D; Lolli-G; Menozzi-C; BrignoleM. Outcome after cavo-tricuspid isthmus ablation in patients with recurrent atrial fibrillation
and drug-related typical atrial flutter. Am J Cardiol 2004; 94(4): 504-8.
43) Solano-A; Menozzi-C; Maggi-R; Donateo-P; Bottoni-N; Lolli-G; Tomasi-C; Croci-F;
Oddone-D; Puggioni-E; Brignole-M. Incidence, diagnostic yield and safety of the implantable
loop-recorder to detect the mechanism of syncope in patients with and without structural heart
disease. Eur Heart J 2004; 25(13): 1116-9.
44) Alboni-P; Brignole-M; Menozzi-C; Raviele-A; Del-Rosso-A; Dinelli-M; Bettiol-K;
Bottoni-N; Solano-A. Clinical spectrum of neurally mediated reflex syncopes. Europace 2004;
6(1): 55-62.
45) Brignole M, Menozzi C, Maggi R, Solano A, Donateo P, Bottoni N, Lolli G, Quartieri F,
Croci F, Oddone D, Puggioni E. The usage and diagnostic yield of the implantable looprecorder in detection of the mechanism of syncope and in guiding effective antiarrhythmic
therapy in older people. Europace 2005; 7:273-9.
46) Tomasi C, De Ponti R, Tritto M, Barilli AL, Bottoni N, Zardini M, Menozzi C, Spadacini
G, Salerno-Uriarte JA. Simultaneous dual fast and slow pathway conduction upon induction of
typical atrioventricular nodal reentrant tachycardia: electrophysiologic characteristics in a series
of patients. J Cardiovasc Electrophysiol 2005;16:594-600.
47) Bottoni N, Donateo P, Quartieri F, Brignole M, Menozzi C. Two unusual cases of
coincident atrioventricular nodal reentrant tachycardia and ventricular tachycardia. Ital Heart J
2005; 6 (9): 765-770.
48) De Ponti R, Verlato R, Bertaglia E, Del Greco M, Fusco A, Bottoni N, Drago F, Delise P,
Ometto R, Mantovan R, Salerno-Uriarte JA and The SWEETT Investigators. Eelectroanatomic
mapping using a novel setting of the window of interest to identify the diastolic pathway and
guide ablation of atypical atrial macrore-entry: data from a multicenter prospective study. Heart
Rhythm 2006; 3 (5) suppl: S75.
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49) Bottoni N, Donateo P, Quartieri F, Lolli G, Maggi R, Oddone D, Brignole M, Menozzi C.
Conservative approach in the ablation of atrioventricular nodal reentrant tachycardia. Europace
2006; 8 (Supplement 1): 218P/8.
50) Bottoni N, De Ponti R, Marazzi R, Quartieri F, Caravati F, De Sanctis V, Menozzi C,
Salerno-Uriarte JA. Ablation of right ventricular outflow tract tachycardia based on
electroanatomic mapping of isolate tachycardia beats. Europace 2006; 8 (Supplement 1): 262/2.
51) Bertaglia E, Zoppo F, Colella A, Bottoni N, Stabile G, Quartieri F, Zerbo F, D’Este D,
Pascotto P. Left atrium ablation for atrial fibrillation: a multicentre perspective registry on
procedural safety. Europace 2006; 8 (Supplement 1): 59PW/3.
52) Inama G, Della Bella P, Landolina M, Tritto M, Bottoni N on behalf of AIAC Council.
Attività dei Laboratori di Elettrofisiologia Italiani nel 2005. G Ital Aritmol Cardiostim
2006;3:185-199.
53) Maggi R, Quartieri F, Donateo P, Bottoni N, Solano A, Lolli G, Tomasi C, Croci F,
Oddone D, Puggioni E, Menozzi C and Brignole M. Comparative study of results of catheter
ablation of ventricular tachycardia from different etiologies. Giornale Italiano di Cardiologia
2006; 7; 11:754-760.
54) De Ponti R, Verlato R, Bersaglia E, Del Greco M, Fusco A, Bottoni N, Drago F, Sciarpa L,
Ometto R, Mantovan R, Salerno-Uriarte JA. Treatment of macro-re-entrant atrial tachycardia
based on electroanatomic mapping: identification and ablation of the mid-diastolic isthmus.
Europace 2007; doi:10.1093/europace/eum055.
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