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Vth INTEGRATED COURSE ENDOCRINE and UROGENITAL SYSTEMS Academic Year : 2016-2017 11 ECTS credits (Basic Medical Sciences Course – II) 2nd year2 semester nd Date :26.08.2016 Undergraduate Required Total 145 h (Basic Medical Sciences Course – II) Lecture: 101 h Laboratory&demonstration: 44 h/6 weeks in Turkish Total 6 weeks Basic Medical Sciences Course - II Lectures: Anatomy: 12 hours Physiology: 42 hours Histology-Embryology: 15 hours Medical Biochemistry: 30 hours Medical Education: 2 hours Laboratory practices: Anatomy: 14 hours Physiology: 4 hours Histology-Embryology: 14 hours Medical Biochemistry: 2 hours Medical Skills: 10 hours Compulsory Lectures (Total 20 h) Principles of Atatürk &History of Revolution: 10 h Foreign Language (English): 10 h Contact: Prof. Dr. Süleyman AYDIN Prof. Dr. Sinan CANPOLAT Prof. Dr. Leyla C. KOYUTÜRK Prof. Dr. Ferit GÜRSU Prof. Dr. Necip İLHAN Prof. Dr. Dilara KAMAN Prof. Dr. Ahmet KAVAKLI Prof. Dr. Enver OZAN Prof. Dr. Murat ÖGETÜRK Prof. Dr. Oya SAĞIROĞLU Doç. Dr. Ahmet ERENSOY Doç. Dr. Oğuz ÖZÇELİK Yrd. Doç. Dr. Tuncay KULOĞLU Aims and Objectives of the Course This course consists of five main topics: the hypothalamus, pituitary gland, peripheral endocrine glands, homeostasis and urogenital system. The development, morphology and the functional aspect of the endocrine and urogenital systems are presented. The course integrates physiological, anatomical and biochemical principles that lead to homeostasis, introducing the general properties of the endocrine system, cellular transduction mechanisms and hormonal transport and assay. Covers the hypothalamic-pituitary axis, hormones of the adrenal, parathyroid, thyroid and pancreas, and calcium and cation homeostasis. Details reproductive endocrinology, gonadal, placental and mammary gland functions with endocrine ontogeny and changes during fetal to pubertal development. Presents metabolic homeostasis from the context of organ-organ interrelationships and the roles of the metabolic hormones: insulin, glucagon, glucocorticoids, catecholamines, thyroid and growth hormone. Lectures will give extensive information on the key concepts. Presentation of various cases will illustrate homeostatic integration involving metabolic and ionic derangements and abnormalities of the reproductive endocrine system. Course contents The teaching subjects of this course are classified under 13 themes. These consecutive themes are organized according to the chain of events as follows: 1- Introduction to endocrinology 2- The Hypothalamus 3- The Pituitary gland 4- Transports and mechanisms of hormone action 5- Growth hormone: its release and functions 6- The neurohypophysis: vasopression and oxytocin 7- Tyroid gland and their metabolic hormones 8- Adrenal glands and their hormones 9- Insulin, glucagon and diabetes mellitus 10- Parathyroid hormone, calcitonin, calcium, phosphate and vitamin D metabolism 11- Reproductive endocrinology in man 12- Reproductive endocrinology in women 13- Lactation and Parturition At least one integrated session is planned for each theme. The theoretical knowledge loaded during the course is interrelated to clinical sciences. The daily course program includes 45minute lectures and/or laboratory and demonstration facilities. Assessment Methods Quizzes and aptitude tests during the course and, practical exams of one each laboratory practices and one written exam at the end of the course is performed. Prerequisite/ Recommended None Textbook/Recommended Reading 1. Arıncı K., Elhan A.. “Anatomi Ders Kitabı” 2. “Sobotta Anatomi Atlası” 3. Dere F., “Anatomi”, Cilt 1-2, Çukurova Üniversitesi Yayınevi, (1988) 4. Williams P.L., “Gray’s Anatomy”, 38th edition, Churchill Livingstone, (1995) 5. Çelebi G., “Tıp ve Diş Hekimliği Öğrencileri İçin Biyofizik”, Çağlayan Kitabevi 6. Çelebi G., “Biyomedikal Fizik”, Barış Yayınları, Fakülteler Kitabevi, (1999) 7. Ganong W.F., (Çeviri: Türk Fizyoloji Bilimler Derneği), “Tıbbi Fizyoloji”, 20. baskı, Nobel Tıp Kitabevi, (2002) 8. Çavuşoğlu H., “Tıbbi Fizyoloji”, “Guyton and Hall”dan çeviri, 10. Baskı, (2000) 9. Guyton A.C., Hall J.E., “Textbook of Medical Physiology”, 10th edition, W. B. Saunders (2000) 10. Junqueira L.C., Carneiro J., Kelley R.O., (Çev. Ed. Aytekin Y)., “Temel Histoloji”, 7. baskı, Barış Kitabevi, (1998) 11. Greenspan FS and Baxter JD. Basic and Clinical Endocrinology, Lange Medical Books; 6th Edition, (2001). 12. Laycock J and Wise P. Essential Endocrinology, Oxford University Press; 3rd Edition, (1996). 13. Fox SI. Human Physiology, McGraw-Hill; 7th Edition, (2001). 14. Ross, MH, Kaye GI and Wojciech P. Histology: a Text and Atlas, Lippincott Williams & Wilkins; 4th Edition, (2002).