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SCIENTIFIC ADVISORY BOARD
Flex Innovation Group, LLC, responsible for the consumer sports shot HOTSHOT®, is a wholly-owned
subsidiary of Flex Pharma, Inc.
Flex Pharma, Inc. is a biotechnology company that is developing innovative and proprietary treatments for
nocturnal leg cramps, cramps and spasms associated with severe neuromuscular conditions.
BRUCE BEAN, PH.D.
Scientific Co-Founder and Co-Chair SAB; Professor of Neurobiology,
Harvard Medical School
Flex Pharma scientific co-founder Dr. Bruce Bean is the Robert Winthrop
Professor of Neurobiology at Harvard Medical School, where he oversees a
leading research lab studying the biophysics of sodium, calcium and potassium
ion signaling in relation to pain processing. Dr. Bean's studies are helping uncover
the molecular basis of ion channels and neuronal electrical firing. These insights
will be instrumental in developing novel medicines to alleviate pain, to treat epilepsy and to address other
disorders related to ion channel pathophysiology. Dr. Bean has extensive experience using
neuropharmacological agents to probe mechanistic aspects of ion channels. Dr. Bean has served on the
Advisory Council for the National Institute of Neurological Diseases and Stroke and on the Scientific Review
Board for the Howard Hughes Medical Institute and his scientific achievements have been recognized through
prestigious awards from the Rita Allen Foundation and the McKnight Foundation. Dr. Bean is a member of the
National Academy of Sciences.
RODERICK MACKINNON, M.D.
Scientific Co-Founder and Co-Chair SAB; Professor, Rockefeller
and HHMI; Nobel Prize 2003
Nobel laureate and Flex Pharma scientific co-founder Dr. Roderick MacKinnon is
an Investigator at Howard Hughes Medical Institute and the John D. Rockefeller
Jr. Professor, Laboratory of Molecular Neurobiology and Biophysics at The
Rockefeller University. His 2003 Nobel Prize in Chemistry focuses on ion channel activation, the foundation of
Flex Pharma’s clinical approach to muscle cramping. He is also the recipient of numerous other scientific
awards, including the 2003 Louisa Gross Horwitz Prize, the 2001 Gairdner Foundation International Award, the
2001 Perl-UNC Neuroscience Prize, the 2000 Lewis S. Rosenstiel Award for Distinguished Work in Basic
Medical Science and the 1999 Albert Lasker Basic Medical Research Award. Dr. MacKinnon is a member of the
National Academy of Sciences. Dr. MacKinnon holds a B.A. in biochemistry from Brandeis University and an M.D.
from Tufts University School of Medicine. He completed his medical residency at Beth Israel Hospital, Harvard
Medical School and postdoctoral work at Brandeis. He joined the faculty at Harvard Medical School before
moving to Rockefeller in 1996.
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SCIENTIFIC ADVISORY BOARD
ALFRED SANDROCK, M.D.
Group Senior Vice President of Development Sciences and Chief
Medical Officer, Biogen
Since joining Biogen in 1998, Dr. Sandrock has held several senior executive
positions, including Senior Vice President of Development Sciences, Senior Vice
President of Neurology Research and Development and Vice President of
Clinical Development, Neurology. During his tenure at Biogen, Dr. Sandrock has
been responsible for the clinical development and approval of Tysabri®,
Plegridy®, Tecfidera®, Alprolix® and Eloctate®. Dr. Sandrock received his B.A. in
human biology from Stanford University, an M.D. from Harvard Medical School
and a Ph.D. in neurobiology from Harvard University. He completed an internship in medicine, a residency and
chief residency in neurology and a clinical fellowship in Neuromuscular Disease and Clinical Neurophysiology
(electromyography) at Massachusetts General Hospital.
ROGER D. TUNG, PH.D.
President and Chief Executive Officer, Concert Pharmaceuticals
Dr. Roger Tung, Ph.D., is the Scientific Founder, President and CEO of Concert
Pharmaceuticals. Before Concert, Dr. Tung was a founding scientist at Vertex,
a pharmaceutical company, where he was employed from 1989 to 2005, most
recently as its Vice President of Drug Discovery. Prior to Vertex, he held
various positions at Merck, Sharp & Dohme Research Laboratories, a global
healthcare provider and The Squibb Institute for Medicinal Chemistry. Dr. Tung
holds a B.A. in chemistry from Reed College and a Ph.D. in medicinal chemistry
at the University of Wisconsin-Madison.
CHRISTOPHER T. WALSH, PH.D.
Professor Emeritus, Department of Biological Chemistry and
Molecular Pharmacology, Harvard Medical School
Christopher Walsh, Ph.D., is a professor emeritus from the Department of
Biological Chemistry and Molecular Pharmacology at Harvard Medical School.
He is currently a consulting professor, Department of Chemistry at Stanford
University and an advisor to the ChEM-H center at Stanford. He is a member
of the National Academy of Sciences and the Institute of Medicine.
© 2017 Flex Innovation Group, LLC, All Rights Reserved.
SCIENTIFIC ADVISORY BOARD
JOHN WINKELMAN, M.D., PH.D.
Associate Professor of Psychiatry, Harvard Medical School
John Winkelman, M.D., Ph.D. is an Associate Professor of Psychiatry at Harvard
Medical School. Prior to Mass General Hospital, he served for 17 years as Medical
Director of the Sleep Health Center of Brigham and Women's Hospital in Boston,
Massachusetts. Dr. Winkelman’s clinical work, teaching and research focuses on
the epidemiology, neurobiology and clinical consequences of primary sleep
disorders. His clinical research has included clinical trials in sleep-related movement disorders, particularly
extensive involvement in the development of approved agents for restless legs syndrome (RLS). Dr. Winkelman
is chair of the American Academy of Neurology practice parameter committee for the treatment RLS, serves on
the Executive Committee of the International RLS Study Group, is an Associate Editor of Sleep and serves on the
editorial boards of Sleep Medicine and CNS Drugs. He has published more than 100 articles, reviews and book
chapters. Dr. Winkelman received his M.D. from Harvard Medical School and his Ph.D. from Harvard University in
Psychobiology. He finished a residency in Psychiatry and a fellowship in Neurology (Sleep Disorders Medicine) at
Mass General Hospital. LARRY KENNEY, PH.D.
Professor of Physiology, Kinesiology and Marie Underhill Noll Chair in
Human Performance at Penn State University
W. Larry Kenney received his Ph.D. in Physiology in 1983. He has been a faculty
member at Noll Laboratory, Penn State University, since that time and is currently
the Marie Underhill Noll Chair in Human Performance as well as Professor of
Physiology and Kinesiology. His research involves human physiological responses
to extreme environments, heat and cold stress, and the biophysics of heat
exchange, with a focus on the impact of aging on these responses.
Dr. Kenney received the prestigious Faculty Scholar medal from Penn State in
2001, as well as the College of Health and Human Development’s Pauline Schmitt
Russell Distinguished Research Career Award and the Evan G. and Helen G. Pattishall Outstanding Research
Career Award. He has published over 200 journal articles and book chapters. He is the lead author of
Physiology of Sport and Exercise, a best-selling textbook in exercise physiology now in its 6th edition.
In addition to his Penn State duties, Dr. Kenney served as President of the American College of Sports Medicine
from 2003-2004 and received the Citation Award from that organization in 2008. He is active in the American
Physiological Society and was an EEP councilor from 1997-2000. He currently serves on the American Council
on Exercise (ACE) Scientific Advisory Panel, Nike’s Scientific Advisory Board, and chaired the Gatorade Sports
Science Institute for several years.
© 2017 Flex Innovation Group, LLC, All Rights Reserved.
SPORTS SCIENCE ADVISORS
BOB MURRAY, PH.D. FACSM
Managing Principal at Sports Science Insights
Bob Murray is managing principal of Sports Science Insights, LLC, a consulting
group for organizations in need of targeted expertise in exercise science and
sports nutrition. SSI’s clients range from start-ups to Fortune 100 companies.
Prior to starting SSI, Dr. Murray was the co-founder and director of the Gatorade
Sports Science Institute from 1985 to 2008. His research on the hydration
needs of athletes and the physiological and performance responses to fluid,
carbohydrate and electrolyte ingestion has contributed to the broader
understanding of the importance of being well hydrated during exercise and of
the role that carbohydrates and electrolytes play in helping athletes and nonathletes alike get the most out of their bodies during physical activity.
Dr. Murray has served on the faculties of Boise State, Ohio State University, and
Oswego State University. He received his PhD in exercise physiology from Ohio State University, is a Fellow of
the American College of Sports Medicine and an honorary member of the Academy of Nutrition and Dietetics.
CHAD PRUSMACK, M.D.
Chief of Neurosurgery at Rocky Mountain Spine Clinic and
Neurosurgery Consultant for the Denver Broncos
Dr. Chad Prusmack is the Chief of Neurosurgery in Denver Colorado at the Rocky
Mountain Spine Clinic. His focus is minimally invasive spine surgery, sports
medicine and integrative health. Additionally, he is the neurosurgical consultant
for the Denver Broncos and the founder of the Resilience Code performance
center. Dr. Prusmack attended Harvard University where he studied Biophysics
and then attended Columbia Medical School. He did his neurosurgery training at
the University of Miami where he completed both spine and skull base surgery
fellowships. Dr. Prusmack performs 400 spine surgeries per year.
© 2017 Flex Innovation Group, LLC, All Rights Reserved.
SPORTS SCIENCE ADVISORS
DON SCOTT
Elite Personal Trainer
As a New York-based personal trainer, Don Scott has built an impressive list of
clients that includes celebrities, CEOs, athletes and some of New York's elite with
his comprehensive approach to fitness. His philosophy mirrors a famous quote
by Thomas Edison: "The doctor of the future will give no medicine, but will
instruct his patients in the care of the human frame, in diet and the cause and
prevention of disease.” Don incorporates corrective exercise and holistic
nutritional guidance to help his clients achieve total well-being. He is passionate
about his work, which is evident in his commitment to each and every client.
Don follows a framework that provides individualized training programs
designed to promote optimal health and vitality. He assesses individuals based
on their lifestyle, health, and fitness goals. Don has over 15 years experience
with a remarkable list of certifications, making him one of the most sought after
fitness expert in NYC.
© 2016 Flex Innovation Group, LLC, All Rights Reserved.