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CHAPTER 21 Nutrition and Digestion c. Absorption is the take up of the products of digestion, usually by the cells lining the digestive tract. d. Elimination is the removal of undigested materials out of the digestive tract. C. 21.3 Digestion occurs in specialized compartments 1. Sponges digest food in vacuoles. 2. Most animals digest food in compartments. 3. Cnidarians and flatworms have a gastrovascular cavity with a single opening, the mouth. a. Food enters the mouth. b. Enzymes break down the food. c. Food particles move into cells lining the compartment. d. Undigested materials are expelled back out the mouth. 4. Most animals have an alimentary canal with a. a mouth, b. an anus, and c. specialized regions associated with one-way flow of food. 5. The normal one-way flow moves food a. into the pharynx or throat, b. down the esophagus to a i. crop where food is softened and stored, ii. gizzard, where food is ground and stored, and/or iii. mach where food is ground and stored, c. to the intestines, where chemical digestion and nutrient absorption occur, and finally d. undigested materials are expelled through the anus. Lecture Outline I. Introduction A. All animals must eat to provide 1. energy and 2. the building blocks used to assemble new molecules. B. Animals also need essential 1. vitamins and 2. minerals. C. The modern human diet in developed countries allows access to relatively cheap and available calorie-dense foods. D. This diet, combined with sedentary jobs and inactive lifestyles, has led to an obesity crisis in the United States leading to 1. 68% of people categorized as overweight and 2. 100 million people categorized as obese. E. Thus, the modern diet appears to be contributing to shorter, less healthy lives. II. Obtaining and Processing Food A. 21.1 Animals obtain and ingest their food in a variety of ways 1. Most animals have one of three kinds of diets. a. Herbivores eat plants and include cattle, snails, and sea urchins. b. Carnivores eat meat and include lions, hawks, and spiders. c. Omnivores eat plants and other animals and include humans, roaches, raccoons, and crows. 2. Animals obtain and ingest their food in different ways. a. Suspension feeders sift small organisms or food particles from water. b. Substrate feeders live in or on their food source and eat their way through it. c. Fluid feeders suck nutrient-rich fluids from a living host. d. Bulk feeders ingest large pieces of food. B. 21.2 Overview: Food processing occurs in four stages 1. Food is processed in four stages. a. Ingestion is the act of eating. b. Digestion is the breaking down of food into molecules small enough for the body to absorb. 262 III. The Human Digestive System A. 21.4 The human digestive system consists of an alimentary canal and accessory glands 1. In humans, food is a. ingested and chewed in the mouth or oral cavity, b. pushed by the tongue into the pharynx, c. moved along by alternating waves of contraction and relaxation by smooth muscle in the walls of the canal in a process called peristalsis, and d. moved in and out of the stomach by sphincters. Copyright © 2012 Pearson Education, Inc. B. C. D. E. F. e. The final steps of digestion and nutrient absorption in humans occur in the small intestine. f. Undigested materials move through the large intestine, feces are stored in the rectum, and then expelled out the anus. 21.5 Digestion begins in the oral cavity 1. Mechanical and chemical digestion begin in the mouth. 2. Chewing cuts, smashes, and grinds food, making it easier to swallow. 3. The tongue a. tastes, b. shapes the food into a ball called a bolus, and c. moves it toward the pharynx. Salivary glands release 1. a slippery glycoprotein that moistens and lubricates food for easier swallowing, 2. buffers that neutralize acids, 3. salivary enzyme amylase that begins the hydrolysis of starch, and 4. antibacterial agents that kill some bacteria ingested with food. 21.6 After swallowing, peristalsis moves food through the esophagus to the stomach 1. Air moves from the pharynx, a. into the larynx, b. past the vocal cords in the voice box, c. into the trachea, and d. into the lungs. 2. Swallowed food and drink move from the pharynx, a. into the esophagus, and b. into the stomach. 3. During swallowing, a. the tip of the larynx moves upward, b. preventing the food from entering the trachea. 21.7 CONNECTION: The Heimlich maneuver can save lives 1. The Heimlich maneuver a. involves a forceful elevation of the diaphragm, b. pushes air into the trachea, and c. can dislodge food from the pharynx or trachea during choking. 2. Brain damage will occur within minutes if no airway is open. 21.8 The stomach stores food and breaks it down with acid and enzymes 1. The stomach can stretch and store up to 2 liters of food and drink. 2. Some chemical digestion occurs in the stomach. 3. The stomach secretes gastric juice, made up of a. mucus, b. a protein-digesting enzyme, and c. strong acid with a pH of about 2 that i. kills ingested bacteria, ii. breaks apart cells in food, and iii. denatures proteins. 4. Pepsinogen and HCl produce active pepsin. a. Pepsinogen, H+, and Cl– are secreted into the lumen of the stomach. b. HCL converts some pepsinogen to pepsin. c. Pepsin helps activate more pepsinogen, starting a chain reaction. d. Pepsin begins the chemical digestion of proteins. 5. What prevents the gastric juices from digesting the walls of the stomach? a. The secretion of pepsin in the inactive form of pepsinogen helps protect the cells of the gastric glands. b. Mucus helps protect the stomach lining against HCl and pepsin. c. New cells lining the stomach are produced about every three days to those that have been damaged. G. 21.9 CONNECTION: Digestive ailments include acid reflux and gastric ulcers 1. Acid reflux of chyme in the stomach back into the esophagus causes the feeling of heartburn. 2. Gastroesophageal reflux disease (GERD) results from frequent and severe acid reflux that harms the lining of the esophagus. 3. Open sores in the lining of the stomach, called ulcers, may form. 4. Bacterial infections (Helicobacter pylori) in the stomach and duodenum can produce ulcers. H. 21.10 The small intestine is the major organ of chemical digestion and nutrient absorption 1. The small intestine is a. named for its smaller diameter, b. about 6 meters long, c. the site of much chemical digestion, and d. where most nutrients are absorbed. 2. The first 25 cm of the small intestine is the duodenum, where chyme squirted from the stomach mixes with digestive juices from the pancreas, liver, gallbladder, and gland cells in the intestinal wall. a. The pancreas produces pancreatic juice containing a mixture of digestive enzymes and an alkaline solution rich in bicarbonate. b. The liver produces bile, which is stored in the gallbladder until it is needed. Bile breaks up fats into small droplets that are more susceptible to attack by digestive enzymes. c. The intestinal wall produces digestive enzymes. 3. The surface area for absorption in the small intestine is greatly increased by a. folds of the intestinal lining, b. fingerlike projections called villi, and c. tiny projections of the surface of intestinal cells called microvilli. 4. Nutrients pass into epithelial cells by a. diffusion and b. against concentration gradients. 5. Fatty acids and glycerol are a. recombined into fats, b. coated with proteins, and c. transported into lymph vessels. 6. Other absorbed nutrients such as amino acids and sugars pass a. out of the intestinal epithelium, b. across the thin walls of the capillaries into blood, and finally c. to the liver. I. 21.11 One of the liver’s many functions is processing nutrient-laden blood from the intestines 1. Blood from the digestive tract drains a. into the hepatic portal vein b. to the liver. 2. The liver performs many functions. The liver a. converts glucose in blood to glycogen, b. stores glycogen and releases sugars back into the blood as needed, c. synthesizes many proteins including blood clotting proteins and lipoproteins that transport fats and cholesterol to body cells, d. modifies substances absorbed in the digestive tract into less toxic forms, and e. produces bile. J. 21.12 The large intestine reclaims water and compacts the feces 1. The large intestine, or colon, a. is about 1.5 m long and 5 cm in diameter, b. has a pouch called the cecum near its junction with the small intestine, which bears a small fingerlike extension, the appendix, c. contains large populations of E. coli, which produce important vitamins, d. absorbs these vitamins and water into the bloodstream, and e. helps form firm feces, which are stored in the rectum until elimination. 2. Diarrhea occurs when too little water is reclaimed from the contents of the large intestine. 3. Constipation occurs when too much water is reclaimed. K. 21.13 EVOLUTION CONNECTION: Evolutionary adaptations of vertebrate digestive systems relate to diet 1. The length of the digestive tract often correlates with diet. In general, the alimentary canals relative to their body size are a. longer in herbivores and omnivores and b. shorter in carnivores. 2. Many herbivores have specializations of the gut that promote the growth of cellulose-digesting bacteria and protists because these animals lack the enzymes needed to digest cellulose in plants. 3. These mutualistic organisms may be housed in a. the cecum, in a coyote or koala, b. the large intestine and the cecum in rabbits and some rodents, or c. the stomach of ruminants such as cattle, sheep, and deer. IV. Nutrition A. 21.14 Overview: An animal’s diet must satisfy three needs 1. All animals have the same basic nutritional needs. Animals must obtain a. fuel to power all body activities, b. organic molecules to build the animal’s own molecules, and c. essential nutrients, or substances the animal cannot make for itself. B. 21.15 Chemical energy powers the body 1. Cellular respiration produces the body’s energy currency, ATP, a. by oxidizing organic molecules digested from food and b. usually using carbohydrates or fats as fuel. 2. A gram of fat has more than twice as many calories as a gram of carbohydrate or protein. 3. The energy content of food is measured in kilocalories (1 kcal = 1,000 calories). 4. Dietary calories are actually kilocalories and are written as Calories. 5. The rate of energy consumption by an animal is called its metabolic rate, the sum of all the energyrequiring biochemical reactions over a given interval of time. 6. The basal metabolic rate (BMR) is the energy a resting animal requires each day. 7. The metabolic rate is the BMR plus the energy needed for physical activity. 8. Excess energy is stored as glycogen or fat. C. 21.16 An animal’s diet must supply essential nutrients 1. Essential nutrients cannot be made from any raw material. 2. There are four classes of essential nutrients. a. Essential fatty acids, such as linoleic acid, are i. used to make phospholipids of cell membranes and ii. found in seeds, grains, and vegetables. b. Essential amino acids are i. used to make proteins and ii. found in meats, eggs, and milk. c. Vitamins are organic nutrients discussed in module 21.17. d. Minerals are simple inorganic nutrients discussed in module 21.17. 3. Malnutrition is a chronic deficiency in calories or one or more essential nutrients. The most common type of human malnutrition is protein deficiency. 4. Undernutrition occurs when a. diets do not supply sufficient chemical energy or b. a person suffers from anorexia nervosa or bulimia. D. 21.17 A healthy human diet includes 13 vitamins and many essential minerals 1. Essential vitamins and minerals are a. required in minute amounts and b. absolutely essential to good health. 2. Vitamins are organic nutrients that may be a. water-soluble, such as vitamins B and C, or b. fat-soluble, such as vitamins A, D, E, and K. 3. Minerals are simple inorganic nutrients. a. Calcium and phosphorus are required in larger amounts. b. Iron is needed to make hemoglobin. c. Iodine is required to make thyroid hormones. d. Most people ingest more salt than they need. 4. The Recommended Dietary Allowances (RDAs) are a. the minimum amounts of nutrients that are needed each day and b. determined by a national scientific panel. 5. Overdoses of vitamins can be harmful. a. In general, excess water-soluble vitamins will be eliminated in urine. b. However, excess fat-soluble vitamins can accumulate to toxic levels in body fat. E. 21.18 SCIENTIFIC DISCOVERY: Scientists use observations and experiments to determine nutritional needs 1. Many insights into human nutrition have come from epidemiology, the study of human health and diseases within populations. a. The essential need for vitamin C was revealed by the high incidence of scurvy in sailors on long sea voyages. b. The need for folic acid to prevent neural tube defects in newborns was revealed by studies of pregnant women of low socioeconomic status. Since 1998, folic acid has been added to foods such as bread and cereals sold in the United States. F. 21.19 CONNECTION: Food labels provide nutritional information 1. Food labels indicate a. serving size, b. calories per serving, c. amounts of selected nutrients per serving and as a percentage of daily value, and d. recommendations for daily limits of selected nutrients. G. 21.20 EVOLUTION CONNECTION: The human health problem of obesity may reflect our evolutionary past 1. Overnourishment is the consumption of more food energy than is needed for normal metabolism. 2. Obesity is the excessive accumulation of fat. 3. The World Health Organization recognizes obesity as a major global health problem. 4. In the United States, the percentage of obese people has doubled to more than 30% in the past two decades. More than 35% are overweight. 5. Weight problems often begin at a young age. a. 15% of children and adolescents in the United States are obese. b. Another 17% are overweight. 6. Obesity leads to a. type 2 diabetes, b. cancer of the colon and breasts, and c. cardiovascular disease. 7. Obesity is estimated to be a factor in 300,000 deaths per year in the United States. 8. A 15-year study published in 2010 indicates that obesity now surpasses smoking in its contribution to disease and the shortening of healthy life spans. 9. The complexity of weight control in humans is evident from studies of the hormone leptin. 10. Leptin a. is produced by adipose (fat) cells and b. suppresses appetite. c. Obese children who have an inherited mutant form of the leptin gene lose weight after leptin treatments. d. However, high levels in otherwise healthy people do not suppress appetite. H. 21.21 CONNECTION: What are the health risks and benefits of weight loss plans? 1. Why are so many people overweight? Is it a. lack of exercise, b. the amount of food, c. the quality of food, or d. a combination of the above? 2. The U.S. market for weight loss products and services has gone from about $60 million a year in 1999 to more than $48 billion a year today. 3. Weight loss diets may a. help individuals lose weight but b. have health risks leading to malnourishment. 4. Some severely obese individuals may be candidates for weight-loss surgery. 5. Scientific studies of weight-loss diets indicate that the best way to lose weight and keep it off is to a. increase exercise and b. eat a balanced diet with adequate amounts of all essential nutrients. I. 21.22 CONNECTION: Diet can influence risk of cardiovascular disease and cancer 1. A healthy diet may reduce the risk of a. cardiovascular disease and b. cancer. 2. Two main types of cholesterol occur in the blood. a. Low-density lipoproteins (LDL) contribute to i. blocked blood vessels and ii. higher blood pressure. b. High-density lipoproteins (HDL) help to reduce blocked blood vessels. i. Exercise increases HDL levels. ii. Smoking decreases HDL levels. iii. Trans fats in the diet tend to increase LDL levels. iv. Eating mainly unsaturated fats tends to lower LDL levels. 3. The relationship between food and health is complex. 4. The American Cancer Society recommends a. regular exercise and b. a diverse diet of healthy foods with an emphasis on plant sources. Vocabulary to know absorption alimentary canal anus appendix basal metabolic rate (BMR) bile bolus bulk feeders carnivores cecum chyme colon crop digestion duodenum elimination esophagus essential amino acids essential fatty acids essential nutrients feces fluid feeders gallbladder gastric juice gastrin gastrovascular cavity gizzard hepatic portal vein herbivores high-density lipoproteins (HDLs) ingestion intestine kilocalorie (kcal) large intestine liver low-density lipoproteins (LDLs) malnutrition metabolic rate microvilli mineral mouth obesity omnivores oral cavity pancreas peristalsis pharynx Recommended Dietary Allowances (RDAs) rectum ruminants salivary glands small intestine sphincter stomach substrate feeders suspension feeders villi vitamin Word Roots carni- = flesh; -vora = eat (carnivore: an animal that mainly eats other animals) chymo- = juice (chyme: the mixture of partially digested food and digestive juices formed in the stomach) gastro- = stomach; -vascula = a little vessel (gastric juice: the collection of fluids [mucus, enzymes, and acid] secreted by the stomach; gastrin: a digestive hormone that stimulates the secretion of gastric juice; gastrovascular cavity: a central cavity in the body of certain animals that functions in both the digestion and distribution of nutrients) herb- = grass (herbivore: an animal that mainly eats plants or algae) kilo- = thousand (kilocalorie: the quantity of heat equal to 1,000 calories, used to measure the energy content of food, and usually referred to as a “calorie”) micro- = small; -villi = shaggy hair (microvillus [plural, microvilli]: one of the many small, fingerlike microscopic projections on the epithelial cells that serve to increase the surface area of the lumen in the small intestine) omni- = all (omnivore: an animal that consumes both meat and plant material) peri- = around; -stalsis = a constriction (peristalsis: rhythmic waves of contraction of smooth muscle that push food along the digestive tract) villius- = shaggy hair (villus [plural, villi]: one of many fingerlike projections of the inner surface of the small intestine, which serve to increase surface area) Name Date Class Ch. 25 Study Guide: On a separate sheet of paper- Use the Chapter 25 Outline to construct a summary for each of the following objectives by converting the appropriate information into paragraph form. Opening Essay Explain why obesity is increasing in the United States. Obtaining and Processing Food 21.1 Define and distinguish between carnivores, herbivores, omnivores, suspension feeders, substrate feeders, fluid feeders, and bulk feeders. 21.2 Describe the four stages of food processing. Explain how animals are protected against self-digestion. 21.3 Compare the structures and functions of a gastrovascular cavity and an alimentary canal. Describe the specialized digestive systems of an earthworm, a grasshopper, and a bird. Human Digestive System 21.4 Describe the main components of the human alimentary canal and the associated digestive glands. 21.5 Describe the functional components of saliva and the types and functions of the teeth in humans. 21.6 Explain how swallowing occurs and how food is directed away from the trachea. 21.7 Explain how the Heimlich maneuver is performed. 21.8 Relate the structure of the stomach to its functions. Describe the functions of the secretions of the stomach. Finally, explain why the stomach does not digest itself. 21.9 Describe the causes and treatments of heartburn, GERD, and gastric ulcers. 21.10 Describe the different types of chemical digestion that occur in the small intestine. Explain how the structure of the small intestine promotes nutrient absorption. 21.11 Explain how the liver helps to regulate the chemical composition of blood. 21.12 Describe the structures and functions of the colon and rectum. Note the causes of diarrhea and constipation. 21.13 Compare the digestive tracts of carnivores and herbivores. Describe how the digestive tracts of a koala and a coyote are specialized to digest cellulose. 21.13 Describe the process of ruminant digestion. Nutrition 21.14 List the three nutritional needs common to all animals. 21.15 Define the basal metabolic rate. Explain how energy is obtained and stored in the body. 21.16 Describe the four classes of essential nutrients. Distinguish between undernutrition and alnutrition. 21.17 Define and distinguish between vitamins and minerals. Distinguish between water-soluble and fatsoluble vitamins. Define the essential minerals and explain why each is important in our diet. 21.17 Define the Recommended Dietary Allowances and explain how they contribute to good health. 21.18 Explain how scientists determine the levels of vitamins and minerals needed in the diet for good health. 21.18 Explain why, since 1998, the United States has required the addition of folic acid to certain foods. 21.19 Describe the types of information found on food labels. 21.20 Describe the obesity epidemic in the United States. Describe the role of leptin in weight management. Explain why cravings for fat may have once been adaptive. 21.21 Describe the best approach to weight control. 21.22 Explain how diet can influence the risks of cardiovascular disease and cancer.