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The Quran and Embryology By Dr. Keith L. Moore Slide Show by A.S. Hashim, MD From http://www.quranandscience.com/human/135-drkeith-moore-confirms-embryology-in-quran.html Dr Keith Moore C.V from Wikipedia, Keith L. Moore is a professor emeritus in the division of anatomy (department of surgery), former Chair of anatomy from 1974 to 1984 and associate dean for Basic Medical Sciences (Faculty of Medicine) at the University of Toronto, Ontario, Canada. He has also worked at the King Abdulaziz University in Jeddah, Saudi Arabia. Moreover, he is a founding member of the American Association of Clinical Anatomists (AACA). He was President of the AACA between 1989 and 1991. He is most known for his textbooks on the subjects of anatomy and human embryology. 3 Embryology and the Quran Dr. Moore has written on "references to embryology in the Quran“ Article published The Journal of the Islamic Medical Association, Vol. 18, Jan-June 1986, pp. 15-16. "A scientist's interpretation of references to embryology in the Quran" 4 Dr. Moore Writes: Statements referring to human reproduction and development are scattered throughout the Quran. It is only recently that the scientific meaning of some of these verses has been appreciated fully. The long delay in interpreting these verses correctly resulted mainly from: inaccurate translations and commentaries and from a lack of awareness of scientific knowledge. 5 Interest in explanations Interest in explanations of the verses of the Quran is not new. People used to ask the prophet Muhammad all sorts of questions about the meaning of verses referring to human reproduction. The Apostle's answers form the basis of the Hadith literature. The translations of the verses from the Quran which are interpreted in this paper were provided by Sheik Abdul Majid Zendani, a Professor of Islamic Studies in King Abdulaziz University in Jeddah, Saudi Arabia. 6 ُ فِي ٍ ت ث َ َاَل ٍ ظلُ َما In three veils of darkness ٍ ُ ق فِي ُ ُ… يَ ْخلُقُ ُك ْم فِي ب ٍ ت ث َ َاَل ٍ ظلُ َما …ٍ ٍ ون أ ُ َّم َهاتِ ُك ْم خ َْلقًا ِم ْن بَ ْع ِد خ َْل ِ ط "He makes you in the wombs of your mothers in stages, one after another, in three veils of darkness." (Quran 39:6) Dr. Moore says: We do not know when it was realized that human beings underwent development in the uterus (womb), but the first known illustration of a fetus in the uterus was drawn by Leonardo da Vinci in the 15th century. 7 Dr. Moore Explains: In the 2nd century A.D., Galen described the placenta and fetal membranes in his book "On The Formation of the Fetus." Consequently, doctors in the 7th century A.D. likely knew that the human embryo developed in the uterus. It is unlikely that they knew that it developed in stages, even though Aristotle had described the stages of development of the chick embryo in the 4th century B.C. The realization that the human embryo develops in stages was not discussed and illustrated until the 15th century. 8 After the Microscope was Discovered After the microscope was discovered in the 17th century by Leeuwenhoek descriptions were made of the early stages of the chick embryo. The staging of human embryos was not described until the 20th century. Streeter (1941) developed the first system of staging which has now been replaced by a more accurate system proposed by O'Rahilly (1972). "The three veils of darkness" may refer to: 1. 2. 3. the anterior abdominal wall; the uterine wall; and the amnio-chorionic membrane (see next slide). 9 Nutfa amshaj: Nutfa means a drop and amshaj means mixtures The Zygote: with 46 chromosomes 10 Pathway of fertilized Ovum 11 The "veils of darkness" are: (1) the anterior abdominal wall; (2) the uterine wall, and (3) the amnio-chorionic membrane. 12 ْ ُن A drop in a place of rest ين ٍ طفَةً فِي قَ َر ٍار َم ِك ْ ُ… ث ُ َّم َج َع ْلنَاهُ ن … ين ٍ طفَةً فِي قَ َر ٍار َم ِك "Then We placed him as a drop in a place of rest." (Quran 23:13) Dr. Moore says: ْ ُ نhas been interpreted as the sperm The drop or nutfah ًطفَة or spermatozoon, but a more meaningful interpretation would be the zygote which divides to form a blastocyst which is implanted in the uterus ("a place of rest"). 13 ْ ث ُ َّم َخلَ ْقنَا الن A leech-like structure ًطفَةَ ََلَقَة ْ … ث ُ َّم َخلَ ْقنَا الن … ًَلَقَة َ َطفَة "Then We made the drop into a leech-like structure." (Quran 23:14) Dr. Moore says: 1. The word "alaqah ًَلَقَة َ " refers to a leech or bloodsucker. 2. This is an appropriate description of the human embryo from days 7-24 when it clings to the endometrium (lining) of the uterus, in the same way that a leech clings to the skin. 3. Just as the leech derives blood from the host, the human embryo derives blood from the decidua or pregnant endometrium 14 Dr. Moore explains: It is remarkable how much the embryo of 23-24 days resembles a leech (See next slide). As there were no microscopes or lenses available in the 7th century, doctors would not have known that the human embryo had this leech-like appearance. In the early part of the fourth week, the embryo is just visible to the unaided eye because it is smaller than a kernel of wheat. 15 Compare human embryo versus the leach 16 A chewed lump ًْضََة ْ فَ َخلَ ْقنَا ْالعَلَقَةَ ُم … ًْضََة ْ … فَ َخلَ ْقنَا ْال َعلَقَةَ ُم "Then of that leech-like structure, We made a chewed lump." (Quran 23:14) Dr. Moore says: The Arabic word "mudghah ًْضََة ْ " ُمmeans "chewed substance or chewed lump." 1. Toward the end of the fourth week, the human embryo looks somewhat like a chewed lump of flesh. 2. The chewed appearance results from the somites which resemble teeth marks. The somites represent the beginnings or primordia of the vertebrae 17 Compare embryo with the chewed gum Top, a drawing of a 28 day-old human embryo showing several bead-like somites The somites resemble the teeth marks in the model of chewed piece of gum. 18 َ س ْونَا ْال ِع The bones in flesh ام لَ ْح ًما َ فَ َك َ ظ َ س ْونَا ْال ِع َ َِ َْضََة … ام لَ ْح ًما ْ … فَ َخلَ ْقنَا ْال ُم َ ظا ًما فَ َك َ ظ "Then We made out of the chewed lump, bones, and clothed the bones in flesh." (Quran 23:14) Dr. Moore says: This indicates that out of the chewed lump stage, bones and muscles form. This is in accordance with embryological development. 1. First the bones form as cartilage models and 2. then the muscles (flesh) develop around them from the somatic mesoderm. 19 Another creature ث ُ َّم أ َ ْنشَأْنَاهُ خ َْلقًا آخ ََر … … ث ُ َّم أ َ ْنشَأْنَاهُ خ َْلقًا آخ ََر Then We developed out of it another creature. (Quran 23:14) Dr. Moore says: This implies that the bones and muscles result in the formation of another creature خ َْلقًا آخ ََر. 1. This may refer to the human-like embryo that forms by the end of the eighth week. 2. At this stage it has distinctive human characteristics and possesses the primordia of all the internal and external organs and parts. 3. After the eighth week, the human embryo is called a fetus. This may 20 be the new creature to which the verse refers. Hearing, Sight, and Understanding ً ار َو ْاْل َ ْفئِدَة َ ۚ قَ ِل ياَل َما َّ وح ِه ۖ َو َج َع َل لَ ُك ُم ال ِ س َّواهُ َونَفَ َخ فِي ِه ِم ْن ُر َ ث ُ َّم َ س ْم َع َو ْاْل َ ْب َ ص َت َ ْش ُك ُرون "And He gave you hearing and sight and feeling and understanding." (Quran 32:9) Dr. Moore says: This indicates that the special senses of hearing, seeing, and feeling َ ار َو ْاْل َ ْف ِئدَة َّ الdevelop in this order, which is true. َ ص َ س ْم َع َو ْاْل َ ْب 1. The primordia of the internal ears appear before the beginning of the eyes, 2. and the brain (the site of understanding) differentiates last. 21 َ … ُمخَلَّقَ ٍة َو ..Partly formed and partly unformed غي ِْر ُمخَلَّقَ ٍة … غي ِْر ُمخَلَّقَ ٍة َ ْضََ ٍة ُمخَلَّقَ ٍة َو ْ … ث ُ َّم ِم ْن ُم “…Then out of a piece of chewed flesh, partly formed and partly unformed..." (Quran 22:5) Dr. Moore says: This seems to indicate that the embryo is composed of both differentiated and undifferentiated tissues. 1. For example, when the cartilage bones are differentiated, the embryonic connective tissue or mesenchyme around them is undifferentiated. 2. It later differentiates into the muscles and ligaments attached to the bones. 22 And to rest in the wombs for an appointed term … سمى َ … َونُ ِقر فِي ْاْل َ ْر َح ِام َما نَشَا ُء ِإلَ ٰى أ َ َج ٍل ُم “…And We cause whom We will to rest in the wombs for an appointed term..." (Quran 22:5) Dr. Moore says: This seems to imply that God determines َونُ ِقر فِي ْاْل َ ْر َح ِامwhich embryos will remain in the uterus until full term. 1. It is well known that many embryos abort during the first month of development, 2. and that only about 30% of zygotes that form, develop into fetuses that survive until birth. 3. This verse has also been interpreted to mean that God 23 determines whether the embryo will develop into a boy or girl. Dr. Moore concludes: The interpretation of the verses in the Quran referring to human development would not have been possible in the 7th century A.D., or even a hundred years ago. We can interpret them now because the science of modern Embryology affords us new understanding. Undoubtedly there are other verses in the Quran related to human development that will be understood in the future as our knowledge increases. 24 Dr. Moore In 1981, during the Seventh Medical Conference in Dammam, Saudi Arabia, Moore said, “It has been a great pleasure for me to help clarify some statements in Quraan about human development. It is clear to me that these statements must have come to Muhammad from God (Allah), because almost all of this knowledge was not discovered until many centuries later. This proves to me that Muhammad must have been a Messenger of God (Allah). 25 Dr. Johnson Johnson, another Anatomist from USA was really surprised and contradicted his own theories that these statements from Holy Quran could be a coincidence, or else Prophet Muhammad (PBUH) had a powerful microscope and in the end said that being a scientist and depending on Quranic verses he believed that Muhammad was receiving information from somewhere and felt that Divine intervention was involved. 26 In Conclusion Embryology in the Quran by Dr. Keith Moore ُ فِي ٍ ت ث َ َاَل ٍ ظلُ َما 1. In three veils of darkness ٍ ْ ُن 2. A drop in a place of rest ِين ٍ طفَةً فِي قَ َر ٍار َمك ْ ً ُ ْ 3. A leech-like structure َلَقَة َ َث َّم َخلَقنَا النطفَة 4. A chewed lump ًْضََة ْ فَ َخلَ ْقنَا ْالعَلَقَةَ ُم َ س ْونَا ْال ِع 5. The bones in flesh ام لَحْ ًما َ فَ َك َ ظ ْ 6. Another Creature ث ُ َّم أ َ ْنشَأْنَاهُ خَلقًا آخ ََر 7. Hearing, Sight, and Understanding 8. ..Partly formed and partly unformed غي ِْر ُمخَلَّقَ ٍة َ … ُمخَلَّقَ ٍة َو 9. And to rest in the wombs for an appointed term 27 THANK YOU Be in Allah’s Care Dr. A.S. Hashim 28