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Advances in diagnostic methods and drug treatment of solid malignant tumors – news from ASCO 2017 Fifth Annual Scientific Conference of Bulgarian Association for Medical Oncology (BAMO) and Bulgarian National Association of Oncology (BNAO) with international participation Hotel Balkan, София 16th – 18th June 2017 Organising Committee: Scientific Committee: Prof. Timcheva,MD, PhD – Chairperson Prof. Dr. Bobev, MD, DMSc Prof. Str. Karanov,MD, PhD – Chairperson Prof. I. Hristozova, MD, PhD М.Taushanova, MD, PhD – Chairperson Prof. J. Rainov, MD, PhD Т. Karanikolova, MD – Secretary Prof. J. Grudeva, MD, PhD Assoc.Prof.I.Mihailova, MD, PhD-Secr. Assoc.Prof. Hr. Ganchev,MD, PhD N. Velikova, MD – Secretary Assoc. Prof. L. Dermendjieva, MD, PhD Assoc. Prof. G.Grigorov, MD, PhD Assoc. Prof. S. Hadjidekova, MD, PhD Assoc. Prof. G. Kirova, MD, PhD Assoc. Prof. M. Nikolov, MD, PhD Assoc. Prof. R. Alexandrova , MD, PhD Assoc. Prof . R. Kaneva, DB, PhD Assoc. Prof. Iv. Shterev, MD, PhD Dr. G. Stamenov, MD, PhD Dr. M. Petrova, MD Dr. B. Krastev, MD Dr. El. Krasteva , MD Dr. Kr. Koinov, MD 1 Members of the Organising Committee: Prof. J. Raynov, MD, PhD N. Miteva, MD M. Koleva, MD Sp. Valev, MD B. Dimitrov, MD 16.06.2017 Friday 08:00 – 19:00 Registration 14:30 – 15:30 Scientific symposium Astelas: Treatment of mCRPC – from the international guidelines to the everyday clinical practice Moderatore: Kr. Koinov, MD 14:30 -14:50 Testosterone levels – significans and factor in the treatment of mCRPC - K. Genova, MD 14:50-15:10 Hormonal treatment of mCRPC – guidelines and reality R. Mangaldjiev, MD 15:10-15:30 Discussion 15:30– 16:00 Opening ceremony Session I Advances in the surgical and radiation treatments of solid malignant tumors. Epigenetics and cancer 2 Moderators: Assoc. Prof. R. Kaneva, DB, Assoc. Prof. G. Grigorov, MD, PhD 16:00 – 16:30 Primary and metastatic liver tumors – surgical treatment opportunities Prof. V. Dimitrova, MD, DMSc 16:30 – 17:00 Malignant spinal cord tumors – possibilities for treatment Assoc. Prof. V. Gerganov, Leitender Oberarzt Neurochirurgie INI Klinik , Hannover – Germany 17:00 – 17:30 Epigenetics and cancer Prof. Claire VOURC'H PhD, Proffesor at University Grenoble Alpes RNA & Epigenetics, Institute for Advanced Biosciences (IAB), France 17:30 – 18:00 ASCO 2017 and radiotherapy of malignant tumors Assoc. Prof. I. Mihailova, MD, PhD 18:00 – 18:15 Discussion 18:15 – 19:15 Scientific symposium AstraZeneca: We can transform now the treatment of patients with ovarian cancer Moderator: Prof. K. Timcheva, MD, PhD 1. Assoc. Prof. R. Kaneva, Molecular Medicine Center, Medical University, Sofia 2. Prof. Dr Nicoletta Colombo PhD , Director, Division of Medical Gynecologic Oncology, European Institute of Oncology, Milan 3. Discussion 20:00 Official dinner 3 18.06.2016 Saturday Session II Advances in the treatment of lung cancer Moderators: Assoc. Prof. G. Kirova, MD, PhD, Assoc. Prof. Hr. Ganchev, MD, PhD 9:00 – 9:30 Immunotherapy of NSCLC - does immunotherapy apply for all NSCLC patients? Dr. Raffaelle Califano - Consultant In Medical Oncology at The Christie NHS Foundation Trust and University Hospital of South Manchester, UK 9:30 – 9:55 Avastin plus Tarceva in the treatment of NSCLC – news from ASCO 2017. Presentation sponsored by Roche - Bulgaria ТВС 9:55 – 10:15 Estimation of radiology response of lung cancer treatment in the era of genomic medicine М. Penkov, MD – St. Iv. Rilski Hospital, Sofia 10:15 – 10:30 Discussion 10:30 – 11:30 Scientific Symposium Boehringer-Ingelheim 11:30 – 12:30 Lunch Session III Drug treatment of breast cancer - what’s new at ASCO 2017? Moderators: El. Krasteva, MD, Assoc. Prof. M. Nikolov, MD, PhD 12:30 – 13:00 ASCO 2017 update on HER2/HR-positive breast cancer Prof. Tanja Cufer, MD, PhD Professor of Oncology, University Clinic Golnik Medical Faculty Ljubljana 4 13:00 – 13:30 Unmet medical needs in adjuvant treatment of HER2 positive Breast Cancer. Scientific medical presentation sponsored by Roche Bulgaria – EOOD ТВС 13:30 – 14:00 Palbocyclib for the treatment of metastatic Breast Cancer with hormonal sensitivity Prof. Timcheva, MD, PhD 14:00 – 14:30 Halaven – the present and the future М. Taushanova, MD, PhD 14:30 – 14:40 Discussion 14:40 – 15:10 Coffee break Session ІV Fertility preservation of patients with oncology diseases Moderators: M. Taushanova, MD, PhD, Assoc. Prof. Baltadjieva, MD, PhD 15:10 - 15:30 Cryoconservation for fertility preservation of oncology patients - an investment in the future St. Nikolova, MHAT “Nadezhda” 15:30 – 16:00 National Consensus for Fertility preservation of oncology patients G. Stamenov, MD, PhD 16:00 – 16:10 Discussion Session V Session for young medical oncologists Moderators: M. Petrova, MD, R. Krasteva, MD А. Colorectal cancer 16:10 – 16:40 Right colon - does it matter when deciding treatment approach in metastatic setting? Prof. Erica Martinelli, MD, PhD, U.O.C. Oncologia Medica ed 5 Ematologia, Dipartimento Medico-Chirurgico di Internistica Clinica e Sperimentale “F. Magrassi e A. Lanzara”, Naples 16:40 – 16:55 Clinical case N1 16:55 – 17:10 Clinical case N2 17:10 – 17:25 Clinical case N3 17:25 – 17:40 Discussion B. Bulgarian scientific projects 17:40 –17:55 Elisaveta Dimitrova, MD 17:55 - 18:10 Nikolay Tsonev, MD 18:10 –18:25 Boris Krastev, MD 18:25 - 18:45 Discussion 18:45 – 19:45 Scientific symposium Eli Lilly 20:00 Dinner 18.06.2017 Sunday Сесия VІ Contemporary achievements in the treatment of gastrointestinal malignant tumors Moderators: Prof. J. Rainov, MD, PhD, N.Miteva, MD 08:30 – 09:00 Pharmacological vigilance during application of biosimilars. Presentation sponsored by Roche Bulgaria. ТВС 09:00 -09:25 Avastin in the treatment of colorectal cancer. Presentation spon sored by Roche Bulgaria ТВС 6 09:25 – 09:55 First line treatment of patients with WT RAS metastatic colorectal cancer - additional data, therapeutic considerations and possibilities supporting treatment decisions Kr. Koynov, MD 09:55 – 10:05 Discussion 10:05 – 10:20 Coffee break Session VIІ Achievements in the drug management of skin malignant tumors Moderators: М. Коleva, MD, T. Karanikolova, MD 10:20 – 10:50 Longterm efficacy of combination Cotellic and Zelboraf in the treatment of inoperable or metastatic malignant melanoma with BRAF V600 mutation. Presentation sponsored by Roche Bulgaria ТВС 10:50 – 11:50 Scientific symposium Novartis: new treatment options for metastatic malignant melanoma 11:50 -12:00 Discussion Session VIІІ Recent advances in the treatment of ovarian malignant tumors. Renal cell carcinoma Moderators: Assoc. Prof. S. Hadjidekova, Sp. Valev, MD 12:00-12:30 NGS of gene panels for diagnostics of familial oncology diseases At. Mitkova, DB 12:30 – 12:50 Ovarian cancer - new conception for the origin and staging - FIGO 2014, AJCC-2016 Prof. S. Popovska, MD, DMSc 7 12:50 – 13:20 What new in the treatment of RCC? TBC 13:20 – 13:30 Discussion 13:30 - 13:40 Proposals for BAMO 2018 13:40 – 13:50 Closure remarks 13:50 Lunch 8