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EMERGENCY MEDICINE UPDATE MARCH 2012 1) Can't take anything from this study on cadavers but it does go against myths that ATLS has given us and this in itself is worthy to mention. The recommendations of ATLS were always to log roll patients 90 degrees and then to slide the board out from under them while checking the back. This according to the authors can cause unacceptable neck motion. It is believed that maintaining in line stabilization is thought to cause less movement and therefore lifting the patient and sliding the board out is safer. OK well, this was cadavers, and who knows if the movement is significant but it makes some sense that it will be harder to maintain neck stabilization when revolving the patient.(J Trauma 70(5)1282). PLEASE REMEMBER- the spine board is for transport only and provides no stabilization of the spine. It causes back pain in normal volunteers for up to three weeks afterwards when left on the board for the usual time most EDs leave patients on these boards. Also can cause pressures sores. Take them off the board immediately. TAKE HOME MESSAGE: The log roll is not holy and may not be the best way to take the patient off a long board. But do get him off fast. 2) This study was surprisingly well done- what was it doing in such a obscure journal? They claim that NTPROBNP levels are high when A fib starts and then go down after 48 hours- how well do they predict left atrium thrombus? If they are good, then you can use this to convert them. Are you a family doc? Do the test, then give some Propafenone and you saved your patient time and money. In this study they took patients with no heart failure and a fib of unknown 24 מתוך1 עמוד EMERGENCY MEDICINE UPDATE duration and did the test. It worked actually very well. (Heart 97(11)914) The problems- there were few patients in each group and even in the low values there were still 5% that had a thrombus so it isn't perfect. False positives aren't so important here because the absence of the NTPROBNP is what we are looking for. But like D Dimer it could be that this is rarely negative. Needs a bigger study. TAKE HOME MESSAGE: NTPROBNP is a new possible way of determining if there is a right atrial thrombus but it needs more study. 3) Good Grief- just when you thought it was safe to go out. Like my pals Rick and Jerry, I can't resist not including one pulmonary embolism article per issue and here we are (did we lose everyone yet? You in the corner- Why aren't you leaving? Oh sorry, didn't mean to wake you up) But this is an important one. There is an entity of non thrombotic pulmonary embolism which can be due to air, amniotic fluids, a variety of other gases and materials, infectious emboli, and fat. D dimer is often negative and CT can be unreliable. (J Thromb Thromb 31(4)436) Of course clinical picture will be very helpful here but little else – perhaps MRI? TAKE HOME MESSAGE: PE can be from other causes than thrombosis- and nothing much will help you with clinching the diagnosis. While we are at it we should mention the Lancet (378(9785)41) article about sending some PE patients home. I do not think there is any argument here the study was well done and the question is just- who qualifies? It is worthwhile mentioning that in this study no one died at home and even in the hospital only one died. Those who were sent home had category one or two PE which has a 24 מתוך2 עמוד EMERGENCY MEDICINE UPDATE mortality of up to 10% but it is clear that probably more could have been sent home since so few died in the hospital. 4) OK, this month's clinical challenge is actually quite easy. This patient underwent a thyroidectomy. (CMAJ 183(8)e498) 5) I have an interest in flight medicine and this is a reminder that the air in the ET tube can expand when ascending. The numbers- if they are important to you are that tracheal mucosal perfusion is impaired at 30 cm H2O and by 50 total blood perfusion is impaired. The study used an in vitro model with ascent to 2400 meter which is less than most airplanes fly but it is what the cabin is pressurized to. Interestingly enough but not surprising from a physics viewpoint is that water filled balloons were unaffected. (PEC 27(5)367).TAKE HOME MESSAGE: In ascent whether they are to mountains or in planes- you must remove air from balloons that may cause impaired perfusion. Now the article that I wanted to do but never got around to. A dermatologist- of all 24 מתוך3 עמוד EMERGENCY MEDICINE UPDATE folks, huh?- did a study to see if air lines in Europe were in compliance with international standards for required equipment for in flight emergencies. None were. A lot of them had weird stuff in their kits including IV aspirin and po placebo. (Trav Med Inf Dis 8(6)388) Now in deference to my Asian readers, EL AL, Qantas (leave off guys, I know Australia is not part of Asia) and Air India were not included in the study. These issues were also discussed in JAMA, 305(19)2003 and they found that flight attendants were ill prepared for in flight emergencies even thought the FAA mandates drills in use of the AED and CPR skills. Standardized recording systems for emergencies do not exist and while on ground medical support exists it is rarely used. TAKE HOME MESSAGE: Be prepared to not be prepared on in-flight emergencies. 6) An article that was just a survey of their center in dealing with nail bed lacerations but the important point here is that plastics repair showed no better results than EPs. I assume the same for FPs as well. This is a laceration- while ugly- that most of us should be able to handle- just be careful if it crosses the germinal matrix. (ibid p375). TAKE HOME MESSAGE: Everyone can sew nailbed lacerations pretty well with good results 7) A great idea and I am sure that the ultrasound geeks that read EMU are already salivating. For pleural effusions, pulmonary edema, pneumothorax and lung consolidation- ultrasound at bedside performed just as well as chest x ray (when CT was used as the gold standard). (Chest 139(5)1140) The kappa was 95% which is very impressive, although not clear to me why they used p values for some 24 מתוך4 עמוד EMERGENCY MEDICINE UPDATE comparisons and Kappas for others. The study did not look at pneumonia and lung masses so you probably have to still do films for these conditions. TAKE HOME MESSAGE: Beside ultrasound can replace chest films for many conditions. 8) We discussed upper extremity PE in last month's issue. Here is some more data. 1% of these patients get PEs which is low for DVTs but 5 of their patients who were on Coumadin fell and bled in their brains and died. (Ann Vasc Suyrg 25(4)442) So do you treat these folks with Coumadin or not? Good question. No answer. There was referral bias in this study as it came from a DVT clinic but this doesn't ehlp us answer this question. TAKE HOME MESSAGE: Upper Extremity DVT needs Coumadin- or maybe not. Or maybe yes. 9) Fads come and go and I have to admit I was a doubter as to how important Vitamin D is. Recently the daily recommended allowances for Vitamin D have increased and we do know that is related to immune function. In this study, patients with sepsis who were vitamin D deficient did worse. They designed the study using APACHE scores, and SOPFA scores. (AEM 18(5)551). This study was not randomized and only had 81 patients, in addition APACHE score is just that – a score. Some patients may have been worse in some aspect of APACHE that may be worse in sepsis or in vitamin D deficiency or both- it is hard to tell. But yes, I probably will go out and get those vitamin D pills. Or at least take my intubated septic patients outside to get some good sun. TAKE HOME MESSAGE: Vitamin D deficient patients may do worse in septic shock. And yes, I did buy those pills 24 מתוך5 עמוד EMERGENCY MEDICINE UPDATE 10) Adam Singer is our guest speaker for this year's scientific assembly. Adam is known to be a paper factory but the great thing about Adam is the originality of his research. Adam brought us a lot of the first articles on gluing wounds, and the article on the use of Docusate for ear wax and many others that I enjoyed. The originality continues- Adam found in a meta analysis that in four countries they sew up abscesses after opening them- which we do not generally do. They healed faster and had no more septic complications. Adam admits that most of this research was done on surgical patients by surgeons on anogenital abscesses but the studies were randomized and showed this works. (AJEM 29(4)361) The big question is that these studies came out of basically four countries- Nigeria, Australia, India and the UK- can it be repeated elsewhere? Adam is an EMU reader for years now, and I am privileged to have spoken to him on many occasions. However, if you are one of those salivating geeks I spoke about before- doing ultrasound guided needle aspiration of skin abscesses did not do as well as traditional incision and drainage. My first inclination was to say, that incision is always better than needle aspiration because needle aspiration is a dynamic process- it is to be done multiple times until the problem resolves. But that was not the point of the article- despite seeing the abscess cavity on ultrasound they frequently came up with taps that had no pus in them. (Ann Emrg Med 57(5)483) Really sounds like this is operator dependant. TAKE HOME MESSAGE: You can sew up abscesses that have been drained but if you use ultrasound to aspirate them, you may not be as successful as incision. 24 מתוך6 עמוד EMERGENCY MEDICINE UPDATE 11) How about some more name dropping. EMU reader and peer reviewer in the past Prof Pinny Halpern has also appeared at our roundtables. They recently published a paper on the use of lidocaine jelly for the insertion of NG tubes (Zonde) versus KY jelly. While this is hard to be double blinded because the jellies do look different but indeed the lidociane jelly caused less gagging and less pain. However it was harder to insert the tube (AJEM 29(4)386). I discussed this with Pinny and this could be because the swallowing mechanism becomes anesthetized and therefore they can't swallow the tube or it could be that KY is more viscous and therefore spreads better and goes further down the GI tract. In either case in Israel we exclusively use lidocaine jelly, but in the USA the use is less common. Nebulized lidocaine is another option that Chris Nickson uses. Give it a try, Huh? TAKE HOME MESSAGE: Lidocaine jelly causes less gagging than KY Jelly 12) OK, I know you are smart. You not only get EMU, but you subscribe to EMA, read Life in the Fast lane and go up on EM Central. So you knew that the case above in # 4 was the Trousseau sign seen in hypocalcemia. But this case is tougher. A fifty year old man has an abscess of the appendix- He is previously healthy. He got cefotaxime and metronidazole in the hospital and was discharged with metronidazole and ciprofloxacin for continuing therapy. 5 days later he is found with hearing loss, vomiting, ataxia and dysarthria. MRI shows: bilateral and symmetric swellings of the cerebellar dentate nuclei, dorsal medulla, dorsal pons, midbrain, corpus callosum and increased signal intensity in the supratentorial periventricular white matter. PS- he was admitted to the ICU. Viral and bacterial cultures were all normal, as was the LP. What happened? TFTs and 24 מתוך7 עמוד EMERGENCY MEDICINE UPDATE Autoimmune markers were also negative. If you are not an ultrasound geek but an IM geek, you should know the answer immediately. (Lancet 378(9787) 288), If you are both an ultrasound and IM geek, you should be writing EMU, not me. 13) OK let's say you are a pediatrician. And you think that despite last month's roundtable on pediatrics I do not spend enough time speaking about kids. So since you immediately knew that the case above was metronidazole induced encephalopathy, so I will give you one. Really not too difficult but I am surprised how many do not know about this condition. Age of onset- 7-12. Girls more than boys. Colicky abdominal pain, often incapacitating, with vomiting and occasional headaches. Nothing really has been proven as helping for treatment. Diagnosis please J Ped Health Care 24(6)372) 14) I won't drag things out- this one was pretty easy. And I didn’t know the original description of the entity goes back to 1986 (Cephalagia 6(4)223). This is abdominal migraine which is very similar to its head equivalent. You do need to rule out other causes of course. 15) ICU corner. These two articles in the same journal (CCM 39(6) 1562) and (ibid 1576) deal with refractory hypoxemia usually due to ARDS. The first article points out that with H1N1 we suddenly had a lot of patients with ARDS who did not have past medical problems and therefore rescue therapies could be tried, in contradistinction to the usual ARDS patients with multiple medical problems who generally die from multi organ failure fairly quickly. The first steps are usually PEEP and prone positioning, but now there are some new players to tryECMO, which worked in 51% of the patients – a very high percentage 24 מתוך8 עמוד EMERGENCY MEDICINE UPDATE of survival for this malady, but it resulted in blood loss. Other therapies include high frequency ventilation which is favored by the Canadians, and airway pressure relief ventilation . If you are not familiar with these therapies, I have hyperlinked you to Wikipedia and CCM tutorials. TAKE HOME POINT: PEEP is the standard for treatment for ARDS. ECMO is an exciting new option. Other therapies are very interesting but unproven. 16) This is an opinion article on acute chest syndrome in Sickle cell Anemia, and while we live very close to Africa and have many patients from Eritrea, Ethiopia and Sudan- I rarely see this disease anymore. The approach they use in Brooklyn at King's County in patients with SCA and a new infiltrate is antibiotics, fluids, oxygen, simple transfusion and occasionally steroids. They like macrolides although I do not and sometimes use exchange transfusions if the patient is doing poorly despite other therapies. (Blood 117(20)5297) The problem is that this is fine when the etiology is pneumonia, may be OK if the etiology is fat embolism but the large majority are of unknown etiology and therefore you can not really know what helps. TAKE HOME MESSAGE: SCA acute chest syndrome is a dangerous disease, but the therapies used are fairly standard- oxygen, transfusion and antibiotics. Harder cases need an exchange transfusion 17) I do a lot of CVP lines-EMU readers know that for fluid status measurements CVP lines are not very accurate. And they also know that we are putting a lot fewer of these. However, we are doing a lot more critical care medicine in the ED, and while you don't have to put in a CVP to give vasopressors, it is what the ICU guys want and it is 24 מתוך9 עמוד EMERGENCY MEDICINE UPDATE probably safer. Furthermore, in my elderly population often we can not find a good vein and this makes life easier in patients who need fluids or meds fast. This article from Hadassah reminds us that CVP placement can cause cardiac tamponade- which is rare but can happen- and if it does it is lethal 50% of the time and can take time to develop so you may not see it immediately. This can be prevented by noticing that the pericardium reflects up 3 cm onto the SVC so if you want to avoid placement in the heart and anywhere near the pericardium so use 15 cm as the maximum insertion of the CVP and the guide wire. The other bad things that can happen with CVP are well known, so I mention this article just as a caution – but I still will be doing them when there is an indication.(Anest Analg 112(6(1280). What I have seen in the literature indicates that femoral lines are the fastest, IJ lines are the safest, SC lines are the ones most often done. TAKE HOME MESSAGE: do not abandon CVP lines but use caution and remember that tamponade is a preventable complication 18) Urinary catheters are often inserted for no good reason,- we know that already- but while in this hospital they were indicated less than half the time- also they showed no benefit most of the time - but the criteria for benefit were not clear to me. What is important from this study is that many who got the catheter could not be weaned from it. (Am J Med Sc 341(6)474) Good work, Dr. Niven who is an EMU reader- did you think I would miss this? TAKE HOME MESSAGE: Think twice before automatically putting in a catheter. You may never be able to get it out. 24 מתוך10 עמוד EMERGENCY MEDICINE UPDATE 19) This is a review article that gives the basics on Trigeminal Neuralgia- but since we do not see so many cases, I will just mention it. Pain is in the trigeminal distribution and it is usually idiopathic but can be due to a tumor or of course, and Multiple Sclerosis which is not a surprise because any neuro complaint can be caused by MS. CT should help if there is a doubt (I am not sure how CT helps in MS) Tegretol is the accepted treatment, but sometimes surgery is the way to go if meds do not help (Post grad Med J 87(1028)410). Now the article doesn't mention Lyrica which may help and I often do infra orbital nerve blocks with a lot of success. TAKE HOME MESSAGE: Tegretol is first line treatment for trigeminal neuralgia, but consider nerve blocks. 20) We mentioned last month about people abusing propofol, but ketamine is now becoming a drug of abuse as well. But if you do abuse drugs- be careful. Other than being stupid you take a risk of significant problems in your GU tract including painful bladder, papillary necrosis, uretic dysfunction and hepatic necrosis. (BJU 107(12)1881) This is only in very high dosages with continual use- our use of ketamine is safe. However, if your colleague is jumping up and down and having hallucinations you may think about….. TAKE HOME MESSAGE: Ketamine abuse is growing and can cause hepato- GU side effects. 21) I have written often about hyperemesis gravidarum but there have been many new subscribers so as long as the literature speaks about this nauseating subject, so will I. I won't describe the condition –we are all familiar with it, but it does recur in people who had it 24 מתוך11 עמוד EMERGENCY MEDICINE UPDATE before. Interestingly the risk is reduced if there is a change in "paternity" although I will not be the one to recommend it to patients. (Not sure my wife would be as hesitant). Tall thin women have a higher rate. H Pylori is often found and should be treated. Here is an interesting statistical error- Twin pregnancy has been associated with having more HG but there is the same incidence of twin pregnancies whether the patients vomit or not which does not say the same thing. In any case ketones can damage the developing fetus and often thiamine deficiency occurs. Amylase can be 5 times the normal value but is of no significance. In the USA they are trying home care, in Israel it is the accepted way of treating this. What works? metoclopramide, antihistamines, ondansetron, pyridoxine (vitamin b 6) all work AND ARE SAFE; Phenothiazines may not be so avoid them. Steroids -not so clear if they work or not, use only if necessary and after the tenth week as cleft palate can occur. Ginger may not be as safe as we thought as it affects testosterone binding and thromboxane synthesis but it is not clear to me if these are really clinically important (Arch Gyn Obstet 283:1183) TAKE HOME MESSAGE: Aside from phenothiazines all medications usually used for vomiting work well in hyperemesis 22) Diuretics- urinating your way to health and happiness? Well, there is very good evidence that diuretics improve symptoms. However they may damage too. They could worsen renal function in high doses and cause neurohumoral activations which make CHF worse. However other research shows some improvement in function due central venous pressure reduction. Hemoconcentration also occurs which 24 מתוך12 עמוד EMERGENCY MEDICINE UPDATE increases the creatinine but improves outcome. There is also additional evidence that KIM 1 receptors and NAG concentrations- no idea what this is- show that diuretics do improve the renal function. (JACC 57(22)2242). I do not think we really know the answer and but we should know that diuretics do not work that fast and are not the first choice in acute pulmonary edema- use CPAP and nitrates which work faster. TAKE HOME MESSAGE: Diuretics definitely improve quality of life. Whether they damage renal function seems to be less clear but new evidence says no. Now Chris Nickson is on the money with what KIM1 and NAG are- here is what he has to say- They're markers of kidney injury http://www.ncbi.nlm.nih.gov/pubmed/11873947 and http://www.ncbi.nlm.nih.gov/pubmed/18414680 23) I really do not want to discuss this article. I think it is reprehensible. That may be a big word for some of you so I will say it differently- this is sick. And sad. Baruch Krauss- an EMU reader writes on the strife between anesthesiologists and EPs with regard to use of sedation. The anesthesiologists want us to take a training program which includes a written knowledge based test and supervised clinical experience on no less than 35 patients. Deep sedation would be granted on a one time limited basis and as decided on by the hospital's anesthesiologists. And only for adults. They claim this is for patient safety but of course the articles show that EPs give sedation just fine with out any more adverse events than the Masters themselves. They do not want us using propofol and I guess after the Murray case I understand, but I agree with Baruch that deep sedation is not equal to anesthesia. Baruch gives some ideas how to handle this at your hospital but one must take into consideration that once it is an official 24 מתוך13 עמוד EMERGENCY MEDICINE UPDATE document it is very hard to get legal footing if G-d forbid something does happen (Ann Emerg Med 57(5)470). In Israel the government has agreed to make this a hospital decision as to who gives the courses on sedation but the anesthesiologists are still fighting this. Silence kills gentlemen, silence kills. 24) This is an article for radiologists but there are some tips for us. We often- maybe too often- do portable chest x rays. I will summarize a few points that may be helpful in understanding these films. Most of the portables are ICU patients so are less relevant to us, but here are some things to remember. We know that AP supine x rays show magnification of the mediastinum, and that low respiration breathing can also cause this. So how do you know if there is real mediastinal widening? Actually kind of surprised about the answer that was givendo a second film and compare it. Another point: White lung. It could be be empyema – which can look a lot like a hemothorax- but empyema takes more time to develop but do not forget lobar collapse Lobar collapse shows crowding and re orientation of pulmonary vessels and elevation of the diaphragm. Next point: Pneumothorax. If it is small it may only be hinted by a deep sulcus sign on the side of the pneumothorax- check for sulci that are unequal. Next point: Pneumomediastinum is often missed – it is multiple lucent streaks that do not change when there is different position of the patient. Pulmonary embolism: often you see nothing, but pleural effusions, lower lung atelactasis, point to this and a Hampton Hump (looks like a pulmonary infarct with a convex medial border and a Westermark sign pulmonary oligema) are rarely there but if they are, they are pretty 24 מתוך14 עמוד EMERGENCY MEDICINE UPDATE sensitive. (AJR 196(supp6) s45) This probably didn't help you so much but let's give you some examples. Here is pneumomediastinum (Courtesyemphysemasymptoms.gass) now for Hampton's hump: 24 מתוך15 עמוד EMERGENCY MEDICINE UPDATE ( Courtesy of Emory) and Westermark's sign: (Courtesy of Medscape).I have to admit that one didn't help me much and I didn't find too many good examples. 25) This review of Toxic Epidermal Necrolysis and Stevens Johnson Syndrome is from CCM 39(6)1521 and it says what you already knewthese patients are really sick and need critical care. But remember how people get into this bad shape- most cases are because of 24 מתוך16 עמוד EMERGENCY MEDICINE UPDATE medication misadventures. You knew that TMP- SMX (Resprim, Bactrim, Septra) causes this. But Cepahlosporins, Penicillins and Quinolones are also on the list although at a Risk Ratio much lower but still very significant. The point is that antibiotics are not innocuous and if you used antibiotics for bronchitis or otitis media and the patient ended up with Steven Johnson, you will find your hind quarters dealing with the men in the black robes. TAKE HOME POINT: antibiotics are not benign! 26) And now some letters from our readers. I heard from Barry Brenner (who was mentioned in our essay two months ago) who reminded me that propofol is a bronchodilator. If so, this may replace ketamine in intubations of respiratory distressed patients with normal blood pressures such as cardiogenic asthma and COPDers who need intubation. Ken Iserson reminds us that that once the the patient has seizures this is eclampsia and not pre eclampsia. There is increase of reflexes in Preeclampsia. Ken we knew that. Really. We were only testing you. I also want to give a plug for Ken's new book which is on a very interesting topic which I have heard Ken lecture on- Improvised Medicine. Some of his ideas are really cool in trying situations. I got a couple of e mails from Life in the Fast Lane. Steve Wake noted that people really do not know about foreign bodies and unnecessary testing gets done for no reason. He brings a case of a patient that had daily x rays until the foreign body passed and he is correct that this was totally unnecessary unless they planned to evaporate the foreign body via radiation. Lastly, Jay Baker reports that his wife doesn't buy the virus –can't do anything schpiel so he uses the 24 מתוך17 עמוד EMERGENCY MEDICINE UPDATE menthol rubs for their placebo effect (and presumably to make his wife happy- you are a nice man). They also use honey for coughs. Actually there is some evidence it may work. EMU LOOKS AT: Movement Disorders and Disorderly Conduct. The first article deals with a subject we tackled a while back. It is on emergency neurology. The source article is Arch Neuro 68(5)567. The second article is the most important article I have read in the last few years- don't miss it. See JEM 41(6)598. It is written by Greg Moore one massively intelligent guy who is an MD/JD and who I have heard speak twice- once at ACEP and once on Risk Management Monthly MOVEMENT DISORDERS 1) NMS-Neuropleptic Malignant Syndrome- this is due to dopaminergic blocking drugs which basically means neuroleptics event the newer ones. Common drugs that must be thought about besides the obvious ones are prochlorperazine (Comapzine), metoclopramide (Pramin, Reglan), Droperidol, and Promethazine (Phenregan). This is a high risk disorder and missing it could be fatal. Often it occurs after changes in dosing. 2) The signs are fever, rigidity- often described as lead pipe, mental status changes, autonomic dysfunction, myoclonus, dystonia and tremor. Since you see these signs and symptoms in Parkinson'sif your patient has Parkinson's and fever, consider NMS. 3) The key lab test here is CPK .Albumin and iron levels are decreased, although many ED s can not check those. 24 מתוך18 עמוד EMERGENCY MEDICINE UPDATE 4) Since these patients have muscle breakdown and are immobile they can suffer from rhabdo, kidney failure, and aspiration pneumonia. 5) Treatment is definitely not evidence based but giving dopaminergic agents seems to help. Bromocriptine is the usual drug. Dantrolene can relax the muscles enough that there will less CPK leak. Do use this therapy for at least a week no matter what the half life of the offending agent is. Do stop the offending med and do not restart it for at least two weeks until after symptoms resolve. In the interim, electric convulsive therapy can resolve the psychosis in the mean time 6) Parkinson Hyperexia Syndrome can look exactly like NMS but this is in a patient with- you guessed it- Parkinson's. We do not do Leovdopa Holidays any more, but if you reduce their dopamine medications you could cause this. Treatment is the same as NMS but methylprednisilone may help here. Here they may not get better and their Parkinson's may become worse permanently. 7) The usual mimic for both these disorders is Serotonin Syndromefever, myoclonus and altered mental status. Here there is much less incidence of rigidity and there may be additionally hyperreflexia, seizures and restlessness which are less seen in NMS. NMS is usually acute while serotonin syndrome improves much faster. CPK is usually not elevated. Causes include SSRIs of course and MAOs, but remember opiates (except morphine), lithium, triptans, LSD and cocaine. Cyproheptadine is the treatment in severe cases, but go find this drug- I haven't seen or used it since the late eighties. This is what the article said- but 24 מתוך19 עמוד EMERGENCY MEDICINE UPDATE Chris has some updated info: We tend to use benzos as the mainstay – if severe intubate and paralyse. We'd use cyproheptadine in mild-moderate cases that benzos weren't sufficient on. Chlorpromazine and olanzepine also have anti-serotonergic effects. By “we”, I mean the Western Australia Poisons Information Centre (WA PIC) I used to work for. 8) Parkinson causes many ED visits and I know the disease unfortunately up close- I diagnosed my father with this early on and while his brain is clear as ever, the physical effects have reduced him to an invalid. He is 87, and we hope for good health and happiness for him. The most common reason for presentation to the ED for these patients is falls. Postural instability is a major part of this disease, but it does not respond to levodopa. Other effects include rigidity bradykinesia, which occur during off periods. Dysautonomia including tachycardia may occur and psychiatric effects may become more pronounced. Consider also concurrent infection, medication changes and metabolic derangements. Dyskinesia may only respond to amantadine or deep brain stimulation. For psychosis, they like clozapine and quietipine. 9) Acute Parkinson's is not Parkinson's! Consider stroke, subdural hematoma, chemo, antiepilptics, anti depressants, CO poisoning, CN, methanol, Whipple disease, HIV encephalitis, central pontine mylenosis, and of course, psychogenic. Remember all this? There will be a test at the end. LEGAL MEDICINE 1) I have refrained from talking about this topic because the legal systems are so different between all the countries that EMU goes to. For example, the USA uses juries and convincing juries is 24 מתוך20 עמוד EMERGENCY MEDICINE UPDATE often more of a case of theatrics and less justice. I have been told that Australia uses a non partial government sponsored panel of medical experts instead of using experts for both sides which is rarely impartial. In Israel, the loser pays court costs. However the principles in this article are very relevant to all systems. Let's get started. 2) You need four elements to prove medical malpractice. You must prove that the physician had a duty to treat that there was a breach of that duty, there was harm to the patient and the harm was caused by the physician's negligence. The main point of this article is that even with all four elements being there you can still get out of a malpractice action. Here is how: 3) Firstly- assumption of risk. If the patient took the risk they can not reasonably sue and win. In Schnieder vs Revici- the patient had a breast lump which was treated in a non traditional manner. She had singed a statement assuming risk. When the cancer spread she sued- and lost. However this defense requires excellent documentation and the signing of consent forms are often in language that is not understandable and therefore not defensible. 4) Good Samaritan: you probably already know about this one however it needs five elements – it has to be an emergency, the provision of care was voluntary, the patient accepts the care, the care is given in good faith to help, and there can be no gross negligence. Now here is the kicker- it can not be for any reimbursement. There are some caveats- in some locales even if you have no duty and relationship to the patient—if you work in that hospital you are responsible for the care rendered. Disasters 24 מתוך21 עמוד EMERGENCY MEDICINE UPDATE may require physicians to come in and render services may be exempted under Good Samaritan. Responding to in hospital emergencies as part of a code team is not exempted from the Good Samaritan law. In an airplane it actually depends on where the plane took off from, where it is when the care is given and where it is going to land. All three jurisdictions could apply. However most countries do have a Good Samaritan law. Be careful- even accepting a drink from the airline that would not have been otherwise provided may drop you from this protection. 5) The next concept is contributory negligence and comparative fault. The former refers to the fact that a patient who contributes to the negligence that led to the malpractice event – then she shares or bears the responsibility. In Ray versus Wagner, the patient had a positive pap test and was unable to be contacted with the results. It was proven that she provided incorrect contact information and therefore bore responsibility. The case was thrown out. In comparative fault percentages of negligence are computed and the patient gets a reduced reward based on the percent of negligence they contributed. In Ostrowski versus Azzara case the plaintiff was a hypertensive diabetic with peripheral vascular disease who was overweight and had uncontrolled diabetes. The defendant removed her toenail that looked infected and gangrene resulted. The defendant showed that the failure to heal was related to the plaintiff's smoking and poor health habits and the court found the defendant only 49% responsible. Of course, to use this defense you must document 24 מתוך22 עמוד EMERGENCY MEDICINE UPDATE very well. If the patient fails to follow through at least you told them what to do. 6) “Sudden emergency” is a concept that a person would not use the same judgment under the pressure of a sudden emergency as they would in a controlled situation. In Ross versus Vanderbilt, a first year resident was injecting lidocaine into a laceration when the patient syncopized. The resident went for help and neglected to protect the patient's head. The patient claimed he had memory loss and tinnitus as a result. The resident claimed that the emergency caused him to do what he normally would not have done and won the case. 7) Respectable minority: is the premise that if there is a respectable minority of physicians that do practice in this manner then malpractice cannot be claimed. In Hamilton versus Hardy, the defendant continued to prescribe oral contraceptives even after that patient claimed she had headaches. In the end she suffered a stroke. The court ruled that the few doctors that would continue prescribing the medication were not enough to drop the case. Had a respectable amount of physicians existed that would continue contraceptives under these conditions- the case would have been dropped. Another example the article brings is that PE in some cases can be sent home based on recent articles (see EMU in Jan) and so if the patient did not do well- it still could be a clean case under respectable minority rule. 8) Two schools of thought is similar. Jones versus Chidester was a case where a tourniquet was used for a bloodless field in orthopedic surgery. Despite opening the tourniquet several times 24 מתוך23 עמוד EMERGENCY MEDICINE UPDATE during the surgery, there was nerve damage. The doctor won because there are many who do use this. Keep in mind that two schools of thought may not necessarily mean professors and academics- it only means what is done in the community. 9) Clinical innovation can be defense when no good evidence exists for the proper treatment. In Brook versus St John’s contrast was injected into the calf instead of the buttocks. There was shortening of the Achilles tendon. The patient then needed surgery. The package insert said specifically injection in the buttocks. But the physician was able to bring articles that said that buttock injection would cause damage to the sciatic nerve and the physician had used the calf successfully in the past. Obviously this requires documentation and explanation to the patient why standard practice is not being followed. This is a difficult defense; try not to go there. 10) Liked this? If you did, let me recommend Risk Management Monthly – Rick Bukata's excellent monthly series on legal issues. In the May issue of EMU we will have a roundtable on legal issues- stay tuned. 24 מתוך24 עמוד