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Pediatric Optometry Lecture 1 Ocular embryology Mutez Gharaibeh,MD ► ► ► ► ► ► ► ► ► ► ► ► ► ► 22/10………. 29/10………. 5/11………… 12/11………. 19/11………. First 26/11………. 3/12………… 10/12………. 17/12………. 24/12………. 31/12………. 7/1………….. Second 14/1…………last date to deliver the report 22/1………… Final ► First : 25 marks . ► Second : 25 marks . ► Report: 10 marks .( How to prescribe eyeglasses in children ). ► Final : 40 ( 30+10 marks). ► 10 marks : evaluation. http://www.med.unc.edu/embryo_images/u nit-eye/eye_htms/eye016.htm [email protected] Weeks 3-4 R O S T R A L Eye fields Anterior neural plate C A U D A L Prosencephalon (forebrain) ► Optic sulcus ► Optic groove ► Optic vesicles. ► Neuroectoderm. - Retina , Iris , Optic nerve. ► Surface ectoderm. - Lens. ► Mesoderm. - vascular and fibrous coats of the eye. Optic groove Ectoderm Lens placode Optic vesicle Lens vesicle Optic stalk Surface ectoderm Optic cup Choroidal fissure normally closes by the 6th week. Optic vesicle Hyaloid artery . Iris colobomas Retinal coloboma Persistent hyaloid artery Mittendorf dot Bergmeister papilla PHPV ► Persistent hyperplastic primary vitreous . Leukocorea Cornea ► Surface ► Inner epithelium- etoderm. layers – Neural crest cells. Optic nerve myelination Incomplete @ birth. ► Complete by 10 weeks of life. ► Stops off the optic never head. ► Eyelids ► Fuse by the beginnig of second trimester ( 13-14weeks of embryogenesis). ► Remain adherent until about the 26 week of embryogenesis. Microphthalmia ► Microphthalmia.? ► Nanophthalmia.? ► Anophthalmia.? ► Cryptophthalmia.؟ ► Cyclopia.?