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1 CHAPTER 23 (8th edition) THE DIGESTIVE SYSTEM part 1 Copyright © 2011 Pearson Education, Inc. 2. Digestive System • Two groups of organs 1. Alimentary canal (gastrointestinal or GI tract) • Digests and absorbs food • Mouth, pharynx, esophagus, stomach, small intestine, and large intestine Copyright © 2011 Pearson Education, Inc. 3. Digestive System 2. Accessory digestive organs • Teeth, tongue, gallbladder • Digestive glands • Salivary glands • Liver • Gall bladder • pancreas Copyright © 2011 Pearson Education, Inc. 4 Fig. 23.1 Pg 852 Mouth (oral cavity) Tongue Esophagus Liver Gallbladder Duodenum Jejunum Small intestine Ileum Anus Copyright © 2011 Pearson Education, Inc. Parotid gland Sublingual gland Salivary Submandibular glands gland Pharynx Stomach Pancreas (Spleen) Transverse colon Descending colon Ascending colon Large Cecum intestine Sigmoid colon Rectum Vermiform appendix Anal canal Figure 22.1 5. Digestive Processes • Six essential activities 1. Ingestion 2. Propulsion 3. Mechanical digestion 4. Chemical digestion 5. Absorption 6. Defecation Copyright © 2011 Pearson Education, Inc. 6 Fig. 23. Pg. 853 Ingestion Mechanical digestion • Chewing (mouth) • Churning (stomach) • Segmentation (small intestine) Chemical digestion Food Pharynx Esophagus Propulsion • Swallowing (oropharynx) • Peristalsis Stomach (esophagus, stomach, small intestine, large intestine) Absorption Lymph vessel Small intestine Large intestine Defecation Copyright © 2011 Pearson Education, Inc. Blood vessel Mainly H2O Feces Anus Figure 22.2 7 Fig. 23.5a; page 855 From mouth (a) Peristalsis: Adjacent segments of alimentary tract organs alternately contract and relax, which moves food along the tract distally. Copyright © 2011 Pearson Education, Inc. (b) Segmentation: Nonadjacent segments of alimentary tract organs alternately contract and relax, moving the food forward then backward. Food mixing and slow food propulsion occurs. Figure 22.3 8. GI tract regulatory mechanisms 2. Intrinsic and extrinsic controls • Enteric nerve plexuses (gut brain) initiate short reflexes in response to stimuli in the GI tract • Long reflexes in response to stimuli inside or outside the GI tract involve CNS centers and autonomic nerves • Hormones from cells in the stomach and small intestine stimulate target cells in the same or different organs Copyright © 2011 Pearson Education, Inc. 9. Peritoneum and Peritoneal Cavity • Peritoneum: serous membrane of the abdominal cavity • Visceral peritoneum on external surface of most digestive organs • Parietal peritoneum lines the body wall • Peritoneal cavity • Between the two peritoneums • Fluid lubricates mobile organs Copyright © 2011 Pearson Education, Inc. Abdominopelvic cavity Vertebra Dorsal mesentery Parietal peritoneum Ventral mesentery Visceral peritoneum Peritoneal cavity Alimentary canal organ Liver (a) Schematic cross sections of abdominal cavity illustrate the peritoneums and mesenteries. Copyright © 2011 Pearson Education, Inc. Figure 22.5a 11. Peritoneum and Peritoneal Cavity • Mesentery is a double layer of peritoneum • Routes for blood vessels, lymphatics, and nerves • Holds organs in place and stores fat • Retroperitoneal organs lie posterior to the peritoneum • Intraperitoneal (peritoneal) organs are surrounded by the peritoneum Copyright © 2011 Pearson Education, Inc. 12 Fig. 23.5b; page 855 Abdominopelvic cavity Mesentery resorbed and lost Alimentary Alimentary canal organ in canal organ a retroperitoneal position (b) Some organs lose their mesentery and become retroperitoneal during development. Copyright © 2011 Pearson Education, Inc. Figure 22.5b 13. Blood Supply: Splanchnic Circulation • Arteries- that branch off the aorta and go to the digestive system and the hepatic portal system • Hepatic, splenic, and left gastric • Inferior and superior mesenteric • Hepatic portal circulation • Drains nutrient-rich blood from digestive organs • Delivers it to the liver for processing Copyright © 2011 Pearson Education, Inc. 14. Histology of the Alimentary Canal • Four basic layers (tunics) • 1. Mucosa • 2. Submucosa • 3. Muscularis externa • 4. Serosa Copyright © 2011 Pearson Education, Inc. 15 Fig. 23.6; page 857 Nerve Artery Vein Mesentery Copyright © 2011 Pearson Education, Inc. Intrinsic nerve plexuses • Myenteric nerve plexus • Submucosal nerve plexus Glands in submucosa Mucosa • Epithelium • Lamina propria • Muscularis mucosae Submucosa Muscularis externa • Longitudinal muscle • Circular muscle Serosa • Epithelium • Connective tissue Lumen Gland in mucosa Lymphatic Mucosa-associated Duct of gland outside vessel lymphoid tissue alimentary canal Figure 22.6 16. 1. Mucosa • Lines the lumen • Functions • Secretes mucus, digestive enzymes and hormones • Absorbs end products of digestion • Protects against infectious disease • Three sublayers: A. epithelium, B. lamina propria, and C. muscularis mucosae Copyright © 2011 Pearson Education, Inc. 17. Mucosa • A. Epithelium • Simple columnar epithelium and mucussecreting cells • Mucus • Protects digestive organs from enzymes • Eases food passage • May secrete enzymes and hormones (e.g., in stomach and small intestine) Copyright © 2011 Pearson Education, Inc. 18. Mucosa • B. Lamina propria ??? • Loose areolar connective tissue • Capillaries for nourishment and absorption • Lymphoid follicles (part of MALT) • C. Muscularis mucosae: smooth muscle that produces local movements of mucosa ??? Copyright © 2011 Pearson Education, Inc. 19. 2. Submucosa • Submucosa • Dense connective tissue ??? • Blood and lymphatic vessels, lymphoid follicles, and submucosal nerve plexus ??? Copyright © 2011 Pearson Education, Inc. 20. 3. Muscularis Externa • Responsible for segmentation and peristalsis • Inner circular and outer longitudinal layers • Myenteric nerve plexus ??? • Sphincters in some regions Copyright © 2011 Pearson Education, Inc. 21. 4. Serosa • Visceral peritoneum • Replaced by the fibrous adventitia in the esophagus skip • Retroperitoneal organs have both an adventitia and serosa skip Copyright © 2011 Pearson Education, Inc. 22 Fig. 23.6 page 857 Nerve Artery Vein Mesentery Copyright © 2011 Pearson Education, Inc. Intrinsic nerve plexuses • Myenteric nerve plexus • Submucosal nerve plexus Glands in submucosa Mucosa • Epithelium • Lamina propria • Muscularis mucosae Submucosa Muscularis externa • Longitudinal muscle • Circular muscle Serosa • Epithelium • Connective tissue Lumen Gland in mucosa Lymphatic Mucosa-associated Duct of gland outside vessel lymphoid tissue alimentary canal Figure 22.6 23. Enteric Nervous System • Intrinsic nerve supply of the alimentary canal • Skip below • Submucosal nerve plexus • Regulates glands and smooth muscle in the mucosa • Myenteric nerve plexus • Controls GI tract motility Copyright © 2011 Pearson Education, Inc. 24. Enteric Nervous System • Linked to the CNS via afferent visceral fibers • skip below • Long ANS fibers synapse with enteric plexuses • Sympathetic impulses inhibit secretion and motility • Parasympathetic impulses stimulate Copyright © 2011 Pearson Education, Inc. 25. Mouth • Oral (buccal) cavity • Bounded by lips, cheeks, palate, and tongue • Oral orifice is the anterior opening • Lined with stratified squamous epithelium Copyright © 2011 Pearson Education, Inc. Soft palate Palatoglossal arch Hard palate Oral cavity Palatine tonsil Tongue Oropharynx Lingual tonsil Epiglottis Hyoid bone Laryngopharynx 26 Uvula Fig. 23.7a Page 857 Palantine bone Palantine process of maxillla Esophagus Trachea (a) Sagittal section of the oral cavity and pharynx Copyright © 2011 Pearson Education, Inc. Figure 22.7a 27. Lips and Cheeks • Contain orbicularis oris and buccinator muscles • Vestibule: recess internal to lips and cheeks, external to teeth and gums • Oral cavity proper lies within the teeth and gums • Labial frenulum: median attachment of each lip to the gum Copyright © 2011 Pearson Education, Inc. 28 Fig. 23.7b; page 859 Gingivae (gums) Palatine raphe Hard palate Soft palate Uvula Palatine tonsil Sublingual fold with openings of sublingual ducts Vestibule Lower lip Upper lip Superior labial frenulum Palatoglossal arch Palatopharyngeal arch Posterior wall of oropharynx Tongue Lingual frenulum Opening of submandibular duct Gingivae (gums) Inferior labial frenulum (b) Anterior view Copyright © 2011 Pearson Education, Inc. Figure 22.7b 29. Palate • Hard palate: palatine bones and palatine processes of the maxillae • Slightly corrugated to help create friction against the tongue • Soft palate: fold formed mostly of skeletal muscle • Closes off the nasopharynx during swallowing • Uvula projects downward from its free edge Copyright © 2011 Pearson Education, Inc. 30. Tongue • Functions include • Repositioning and mixing food during chewing • Formation of the bolus • Initiation of swallowing, speech, and taste • Intrinsic muscles change the shape of the tongue • Extrinsic muscles alter the tongue’s position • Lingual frenulum: attachment to the floor of the mouth Copyright © 2011 Pearson Education, Inc. 31. Tongue • Surface bears papillae • taste buds Copyright © 2011 Pearson Education, Inc. Epiglottis Palatopharyngeal arch Palatine tonsil Lingual tonsil cluster of lymphoid follicles Palatoglossal arch Terminal sulcus Foliate papillae Circumvallate papilla Midline groove of tongue Dorsum of tongue 32 Fig. 23.8 Page 860 Fungiform papilla Filiform papilla Copyright © 2011 Pearson Education, Inc. Figure 22.8 33. Salivary Glands • Extrinsic salivary glands (parotid, submandibular, and sublingual) Copyright © 2011 Pearson Education, Inc. 34. Salivary Glands • Intrinsic (buccal) salivary glands are scattered in the oral mucosa - no ducts • Secretion (saliva) • Cleanses the mouth • Moistens and dissolves food chemicals • Aids in bolus formation • Contains enzymes that begin the breakdown of starch (amylase) Copyright © 2011 Pearson Education, Inc. 35. Salivary Glands • Parotid gland • Anterior to the ear external to the masseter muscle • Parotid duct opens into the vestibule next to second upper molar • Submandibular gland • Medial to the body of the mandible • Duct opens at the base of the lingual frenulum Copyright © 2011 Pearson Education, Inc. 36. Salivary Glands • Sublingual gland • Anterior to the submandibular gland under the tongue • Opens via 10–12 ducts into the floor of the mouth Copyright © 2011 Pearson Education, Inc. 37 Fig. 23.9 page 861 Tongue Teeth Parotid gland Ducts of sublingual gland Frenulum of tongue Sublingual gland Mylohyoid muscle (cut) Anterior belly of digastric muscle (a) Submandibular gland Parotid duct Masseter muscle Body of mandible (cut) Posterior belly of digastric muscle Submandibular duct Mucous cells (b) Copyright © 2011 Pearson Education, Inc. Serous cells forming demilunes Figure 22.9 38. Composition of Saliva • Secreted by serous and mucous cells • 97–99.5% water, slightly acidic solution containing • Salivary amylase and lingual lipase PLAY Animation: Rotatable head Copyright © 2011 Pearson Education, Inc. 39. Control of Salivation • Intrinsic glands continuously keep the mouth moist • Extrinsic salivary glands produce secretions when • Ingested food stimulates chemoreceptors and mechanoreceptors in the mouth - Smell • Strong sympathetic stimulation inhibits salivation and results in dry mouth (xerostomia) Copyright © 2011 Pearson Education, Inc. 40. Teeth • Primary and permanent dentitions are formed by age 21 • 20 deciduous teeth erupt (6–24 months of age) • Roots are resorbed, teeth fall out (6–12 years of age) as permanent teeth develop • 32 permanent teeth • All except third molars erupt by the end of adolescence Copyright © 2011 Pearson Education, Inc. 41 (b) Figure 23.10; page 862 Deciduous teeth Copyright © 2011 Pearson Education, Inc. Permanent teeth Figure 22.10b 42. Classes of Teeth • 2I, 1C, 2P, 3M • Incisors • Chisel shaped for cutting • Canines • Fanglike teeth that tear or pierce • Premolars (bicuspids) and molars • Have broad crowns with rounded cusps for grinding or crushing Copyright © 2011 Pearson Education, Inc. 43 Figure 23.10; page 863 Incisors Central (6–8 mo) Lateral (8–10 mo) Canine (eyetooth) (16–20 mo) Molars First molar (10–15 mo) Second molar (about 2 yr) (a) Copyright © 2011 Pearson Education, Inc. Deciduous (milk) teeth Incisors Central (7 yr) Lateral (8 yr) Canine (eyetooth) (11 yr) Premolars (bicuspids) First premolar (11 yr) Second premolar (12–13 yr) Molars First molar (6–7 yr) Second molar (12–13 yr) Third molar (wisdom tooth) (17–25 yr) Permanent teeth Figure 22.10a 44. Tooth Structure • Crown: the exposed part above the gingiva (gum) • Covered by enamel—the hardest substance in the body (calcium salts and hydroxyapatite crystals) • Root: portion embedded in the jawbone • Connected to crown by neck Copyright © 2011 Pearson Education, Inc. 45. Tooth Structure • Cementum: calcified connective tissue • Covers root and attaches it to the periodontal ligament • Periodontal ligament • Forms fibrous joint called a gomphosis • Gingival sulcus: groove where gingiva borders the tooth Copyright © 2011 Pearson Education, Inc. 46. Tooth Structure • Dentin: bonelike material under enamel • Maintained by odontoblasts of pulp cavity • Pulp cavity: cavity surrounded by dentin • Pulp: connective tissue, blood vessels, and nerves • Root canal: extends from pulp cavity to the apical foramen of the root Copyright © 2011 Pearson Education, Inc. Crown Neck Root Enamel Dentin Dentinal tubules Pulp cavity (contains blood vessels and nerves) Gingiva (gum) Cementum 47 Root canal Periodontal ligament Figure: 23.11 Page: 863 Apical foramen Bone Copyright © 2011 Pearson Education, Inc. Figure 22.11 48. Tooth and Gum Disease • Dental caries (cavities): gradual demineralization of enamel and dentin • Dental plaque (sugar, bacteria, and debris) adheres to teeth • Acid from bacteria dissolves calcium salts • Proteolytic enzymes digest organic matter • Prevention: daily flossing and brushing Copyright © 2011 Pearson Education, Inc. 49. Tooth and Gum Disease • Gingivitis • Plaque calcifies to form calculus (tartar) • Calculus disrupts the seal between the gingivae and the teeth • Anaerobic bacteria infect gums • Infection reversible if calculus removed Copyright © 2011 Pearson Education, Inc. 50. Tooth and Gum Disease • Periodontitis • Immune cells attack intruders and body tissues • Destroy periodontal ligament • Activate osteoclasts • Consequences • Possible tooth loss, promotion of atherosclerosis and clot formation in coronary and cerebral arteries Copyright © 2011 Pearson Education, Inc.