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Exercise, Urinary-Water, Electrolytes, and Acid-base Balance-2 1) ___ is NOT a function of the urinary system. a. Excreting wastes b. Regulating blood O2 and CO2 d. Detoxifying drugs c. Regulating acid-base balance 2) Water flows from _____. a. a high osmotic concentration to a low osmotic concentration b. a low osmotic concentration to a high osmotic concentration 3) When the blood passes glomeruli, ___ is filtered into tubular system. a. ~ 20% of blood cells b. ~ 20% of plasma proteins c. ~20% of plasma water and electrolytes 4) Glomerular filtration rate ____. a. is quite constant b. fluctuates dramatically 5) Glomerular filtration membrane ___. a. includes the foot processes of the podocytes permeable to amino acids b. is not permeable to glucose 6) Which of the following is not a component of a nephron? a. proximal convoluted tubule b. glomerulus c. afferent arteriole c. is not d. renal artery 7) Which of the following is not a nitrogenous waste? a. urea b. uric acid c. ammonia d. amino acid 8) Which of the renal functions can be substituted by hemodialysis? a. producing erythropoietin b. eliminating wastes c. deamination 9) ___ is not included in the four processes of urine formation. a. Glomerular filtration b. Tubular reabsorption c. Tubular secretion e. Storage of urine in the bladder d. Concentrating urine 10) The fluid in ____ is called urine (but not glomerular filtrate or tubular fluid). a. glomeruli b. proximal tubules c. distal tubules d. renal calyx 11) The proximal convoluted tubules reabsorb ___ of the glomerular filtrates. a. 20-30% b. 40-50% c. 60-70% d. 80-90% 12) ___ is one of the mechanisms for tubular reabsorption. a. Chemotaxis b. Insulin c. Dialysis d. Solvent drag 13) If Na-K-ATPase in basal membranes of proximal tubules is eliminated, tubular reabsorption of glucose will ___ . a. decrease b. increase c. not change 14) Glucose is present in the urine of diabetic patients because ____. a. tubular cells actively secrete glucose into tubular fluid b. tubular cells reabsorb much less glucose c. the amount of glucose in tubular fluid exceeds the transport maximum (Tm) 15. The tubular cells do not secrete ___ into tubular fluid. a. amino acids b. uric acid c. H+ d. HCO3- 16. The nephron loop (Loop of Henle) ___. a. reabsorbs two thirds of glomerular filtrates c. reabsorbs Na+ and Cl- b. concentrates urine 17. Aldosterone affects the function of ___ 1 Exercise, Urinary-Water, Electrolytes, and Acid-base Balance-2 a. proximal tubule b. loop of Henle c. distal tubule 18. Aldosterone enhances the reabsorption of ___. a. Na+ b. K+ c. Ca++ d. phosphate 19. Atrial natriuretic factor ___. a. enhances reabsorption of Na+ b. inhibits reabsorption of Na+ 20. A collecting duct ___. a. connects several distal tubules b. dilutes urine c. enhances reabsorption of water c. reabsorbs 2/3 of glomerular filtrates 21. ADH ___. a. decreases the permeability of collecting ducts to water b. increases the permeability of collecting ducts to water 22. A minimum of ___ urine has to be produced to excrete nitrogenous wastes. a. 1-2 liter/day b. 400 ml /day c. 125 ml/min 23. Diabetes insipidus ___. a. is caused by the lack of ADH b. is accompanied with oliguria c. is caused by the lack of insulin 24. Which of the following can cause glycosuria (presence of glucose in urine)? a. drinking two 12 oz cans of regular Coke by a healthy person b. the lack of insulin ADH c. the lack of 25. Which of the following does NOT cause diuresis? a. caffeine b. diuretics c. ADH 26. How much of the glomerular filtrate is finally excreted as urine? a. ~ 60% b. ~ 70% c. ~ 80% d. ~ 1% 27. When urine volume exceeds 400 ml (enough to stimulate the stretch receptors) in an adult urinary bladder but the time/place do not allow urination, ___. a. the external urethral sphincter relaxes but the internal sphincter contracts b. the external urethral sphincter contracts but the internal sphincter relaxes c. both the internal and external urethral sphincters relax d. both the internal and external urethral sphincters contract 28. About ___ of total body weight is water. a. 40% b. 50% c. 60% d. 90% 29. The three body fluid compartments include all of the following except ___. a. the kidneys b. plasma c. intracellular fluid d. tissue fluid 30. When placed in distilled water (0 mOsm), erythrocytes___. (The plasma membranes of erythrocytes are permeable to water) a. shrink b. swell c. do not shrink or swell 31. Water loss via ___ is controlled physiologically. a. respiration b. urine c. sweating d. feces 32. Water loss via ___ can be avoided. a. respiration b. urine d. feces 33. Thirst is felt when ___. a. blood volume decreases c. sweating b. plasma osmolarity decreases c. blood volume increases 2 Exercise, Urinary-Water, Electrolytes, and Acid-base Balance-2 34. The feeling of thirst is generated in ____. a. mouth b. throat c. spinal cord 35. Edema can be caused by ___. a. increased capillary reabsorption d. hypothalamus b. decreased capillary filtration c. occlusion of lymphatic vessels 36. Which ion is the most abundant in intracellular space? (hint: consider intra- vs extracellular distribution of each ion) a. K+ b. Na+ c. Ca++ d. Cl37 . Which ion primarily determines the resting membrane potential? a. K+ b. Na+ c. Ca++ d. Cl38. Which hormone is the primary regulator of plasma Na+ concentration? a. PTH b. calcitonin c. aldosterone 39. The osmolarity of extracellular fluid is mainly contributed by ___. a. NaCl b. K+ c. PO4 40. Which ion serves as a second messenger? a. Clb. Na+ c. Ca++ 41. Which ion is a blood clotting factor? a. K+ b. Na+ c. Ca++ 42. Which hormone decreases plasma Ca++ concentration? a. PTH b. calcitonin c. thyroid hormone 43. Which hormone decreases plasma K+ concentration? a. aldosterone b. Calcitonin c. calcitrol 44. Calcitrol ___. a. is not a derivative of vitamin D absorption of Ca++ in small intestines b. decreases plasma Ca++ concentration c. increases 45. ___ is absolutely needed for the synthesis of ATP. a. K+ b. Na+ c. Ca++ d. PO4346. When H+ concentration increases, pH ___. a. increases b. decreases c. does not change 47. A buffer minimizes ___. a. the increase but not decrease in pH and decrease in pH b. the decrease but not increase in pH 48. ___ is NOT a major buffer in human body. a. HEPES buffer b. Bicarbonate buffer c. Protein buffer 49. ___ are NOT involved in regulating plasma pH. a. Chemical buffers b. Respiratory system c. Kidneys c. both increase d. Phosphate buffer d. Baroreceptors 50. Renal tubules secretes H+ when ___. a. plasma pH is high b. plasma pH is low 51. ___ can actually excrete H+ out of the body. a. Chemical buffers. b. The lungs c. The kidneys 3 Exercise, Urinary-Water, Electrolytes, and Acid-base Balance-2 52. Hypoventilation causes ___. a. respiratory acidosis b. metabolic alkalosis c. metabolic acidosis 53. Diabetes mellitus causes ___. a. respiratory acidosis b. respiratory alkalosis c. metabolic acidosis 54. Chronic vomiting causes ___. a. metabolic alkalosis b. respiratory alkalosis c. metabolic acidosis 55. The pH of blood samples from person A and person B is 7.2 and 7.5, respectively. Which of the following statements about the two blood samples is correct? A. There are more H+ ions in person B’s blood than person A’s blood. B. There are more H+ ions in person A’s blood than person B’s blood. C. There are more Na+ ions in person A’s blood than person B’s blood. D. There are more Cl- ions in person A’s blood than person B’s blood. E. There are more Ca++ ions in person A’s blood than person B’s blood. 56. A. B. C. D. The pH of blood samples from person A and person B is 7.1 and 7.6, respectively. Which of the following statements about the two blood samples is correct? Person A has alkolosis. Person B has acidosis. None of the above Both of the above 57. A normal person can use ___ to resist the changes in his/her blood pH. A. the chemical buffers in the blood B. the digestive system C. the kidneys D. two of the above E. all of the above 58. A. B. C. D. E Which of the following organs can excrete excess H+ ions out of a human body in the case of acidosis? stomach lung kidneys liver spleen 4 Exercise, Urinary-Water, Electrolytes, and Acid-base Balance-2 KEY 1b 2b 3c 4a 5a 6d 7d 8b 9e 10d 11c 12d 13a 14c 15a 16c 17c 18a 19b 20a 21b 22b 23a 24b 25c 26d 27b 28c 29a 30b 31b 32c 33a 34d 35c 36a 37a 38c 39a 40c 41c 42b 43a 44c 45d 46b 47c 48a 49d 50b 51c 52a 53c 54a 55b 56c 57d 58c 5