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The Examination Paper of Jinan University Course Name: For Instructors Course Type Semester: 1st [ ] 2nd[ ] Academic Year : 2005–2006 Required [ ] Elective [ ] Way of the Exam physiology open-book [ ] close-book [ ] the Form of the Exam Paper Date of the Examination (A/B…) [ C] Instructor’s Name Sichun He, Liwei Wang, Yuechun Wang School Total Pages 8 Major Grade _________________________ For Examinees Name Student No. Mainland Student [ ] Question No. Ⅰ Ⅱ Ⅲ Non-mainland Student [ ] Ⅳ Ⅴ Ⅵ Ⅶ Ⅷ Ⅸ Ⅹ Total Score Score Ⅰ.Choose the best answer (40points, 1 point per question, please circle the best answers). 1. Most of the CO2 transported in the blood is A Dissolved in plasma B In carbamino compounds C Bound to ClD In HCO32. Increase of arterial CO2 concentration increases pulmonary ventilation. The receptors responsible for this effect are the A. Chemoreceptor in the medulla B Aortic baroreceptors C Chemoreceptor in the alveoli D Chemoreceptor in the trachea and large bronchi 3. Variations in which of the following components of blood or cerebrospinal fluid do not affect respiration? A Cerebrospinal fluid H+ concentration B Arterial H+ concentration C Arterial Na+ concentration D Arterial CO2 concentration 4. Which of the following statements about quiet respiration is wrong? A Diaphragm contracts during inspiration. 1 B External intercostal muscles contracts during inspiration. C. Inspiratory muscles relax during expiration. D. Expiratory muscles contract during expiration. 5. Which of the following is not the function of the surfactant in the lung? A. Increasing the surface tension B. Facilitating ventilation C. Preventing the lungs from collapse D. Prevent the lung from edema 6. Which of the following statements about intrapleural pressure in quiet respiration is wrong? A. Intrapleural pressure is the pressure in the pleural cavity B. Intrapleural pressure is caused by the elastic recoil of the lung C. Intrapleural pressure facilitates lung ventilation D. Intrapleural pressure decreases blood return 7. In which part of the brain is the basic rhythm of respiration generated mainly? A. Medulla B. Pons C. Cerebral cortex D. Hypothalamus 8. Which of the following cells in the stomach secrets intrinsic factor? A. Neck cell B. G cell C. Chief cell D. Parietal cell 9. Pepsinogen can be activated by A. Cl B.Na+ C. K+ D. HCl 10. Which of the following is not the component of gastric juice? A. HCl B. Lipase C. Mucus D. Pepsinogen 11. Which of the following is not the substance secreted by the gastrointestinal tract? A. Gastrin B. Secretin C. Cholecystokinin (CCK) D. Aldosterone 12. Which of the following statements is wrong? A. Bile salts are secreted by the liver. B. Bile is stored in gallbladder. C. Bile salts emulsify the large fat particles of the food into many minute particles. D. Bile contains the enzyme to digest fats. 13. Glucose and amino acids in the renal filtrate are normally reabsorbed in the A. Distal tubule B. Cortical collecting duct C. Loop of Henle D. Proximal tubule 2 14. Which of the following factors decreases glomerular filtration rate? A. Decrease of glomerular hydrostatic pressure B. Decrease of hydrostatic pressure in Bowman's capsule C. Decrease of colloid osmotic pressure of the glomerular capillary plasma D. Increase of colloid osmotic pressure in Bowman's capsule 15.The incorrect statement about the chemical receptors in the carotid bodies and aortic bodies is that A. They are sensitive to oxygen lack in the blood. B. They are sensitive to carbon dioxide excess in the blood. C. They are sensitive to hydrogen ion excess in the blood. D. They are sensitive to water excess in the blood. 16.The basic way for nervous regulation is the A. Response B. Reflex C. Secretion D. Conduction 17.The correct statement about the facilitated diffusion is that A. The substances are transported through the membrane channels. B. The substances are transported through the intermolecular spaces. C. The substances are transported through the carrier proteins. D. The substances are transported against their concentration gradients. 18.Which of the following factors can increase the rate of diffusion for a water-soluble substance? A. Decrease of its concentration gradient B. Decrease of the number of the protein channel. C. Decrease of its molecular size. D. Decrease of the temperature 19.The correct statement about the action potentials is that A. They are present only in nerve and muscle cells. B. They play a little role in controlling the cell’s functions. C. They can be created by the diffusion of the ions. D. They can be created by osmosis. 20.The incorrect statement about the propagation of action potentials is that A. An action potential elicited at any point of the membrane can excite adjacent portions of the membrane. B. It propagates to the entire membrane with certain diminishment of its amplitude. C. It propagates via the local current. D. It propagates in the saltatory way in the myelinated nerve fibers. 21.The correct statement about the effect of sympathetic nerve on the heart is that A. The excitation of sympathetic nerve can decrease the heart rate. B. The excitation of sympathetic nerve can greatly decrease the strength of the ventricular contraction. C. The excitation of sympathetic nerve can increase the heart rate to as high as 180 to 200 beats per minute in adult person. D. The excitation of sympathetic nerve can only slightly increase the strength of the ventricular contraction. 22.One of the characteristics of the isovolumic contraction is that A. There is a great decrease of ventricular pressure without the changes of the volume of the ventricle. B. There is a great increase of ventricular pressure without the changes of the volume of the ventricle. C .Both the mitral valve and aortic valve are open. 3 D.70% of the blood ejection occurs in this period. 23.The incorrect statement about the A-V node is that A. They conduct action potential at a high velocity. B. They are very small fibers. C. They have a few intercalated discs. D. They have almost no contractile filaments. 24.At normal condition, the normal pacemaker is located at A. The sinus node B. The A-V node C. The Purkinje fibers D. The ventricular muscle cells 25.The arterial pressure is characterized by A. The high pressures and great pressure pulsation during a cardiac cycle. B. The low pressures and great pressure pulsation during a cardiac cycle. C. The high pressures and small pressure pulsation during a cardiac cycle. D. The low pressures and small pressure pulsation during a cardiac cycle. 26.Which of the following factors may increase the central venous pressure? A. Increase of the pumping blood of the heart B. Massive blood transfusion C. Lost of a large amount of blood D. Decrease of the blood back into the right atrium 27.The correct statement about the vasopressin is that A. It is one of the neurohormones. B. Normally, a large amounts of it are secreted. C. It is also called antiduretic hormone. D. It is a very powerful vasoconstrictor. 28.One of the characteristics of the sympathetic innervations of the blood vessels is that A. Sympathetic vasomotor nerve fibers originate from the brainstem. B. Only the large arteries are innervated by the sympathetic nerves. C. The sympathetic nerves carry a larger numbers of vasoconstrictor fibers and only a very few vasodilator fibers. D. Excitation of the sympathetic vasomotor nerve fibers can decrease the arterial blood pressure. 29.Postsynaptic inhibition depends on A. Reduced action potential amplitude B. Increased transmitter release C. Increased postsynaptic potential D. Inhibitory interneuron 30. Presynaptic inhibition depends on A. Reduced action potential amplitude B. Reduced transmitter release C. Increased postsynaptic potential D. IPSP produced in postsynaptic neuron 31.Synaptic innervation of a number of fibers by one neuron is an example of A. Convergence B. Chronaxie C. Rheobase 4 D. Divergence 32.The inhibitory synaptic potential recorded from the cell body of a CNS neuron A. Cannot be summed either temporally or spatially B. Involves a selective increase in the permeability to K+ and Cl- ion C. Involves a selective increase in Ca2+ permeability D. Is not a normal occurrence during spinal reflex activity 33.Which of the following determines whether release of neurotransmitter at synaptic junctions result in an excitatory effect on postsynaptic neuron? A. The amount of the neurotransmitter B. The properties of the postsynaptic receptor C. The rate of reuptake of neurotransmitter by the presynaptic cell. D. The amount of calcium released from presynaptic axons 34.The EPSP recorded from the cell body of a CNS neuron A. Lasts only for the duration of the presynaptic action potential B. Can be spatially summated during repetitive firing of several neurons C. Is an all-or-none response to a presynaptic impulse D. Can be temporally summated during repetitive postsynaptic stimulation 35.Gamma-aminobutyric acid(GABA) A. Hyperpolarizes motoneurons and inhibitory in nature B. Is blocked by strychnine C. Is blocked by glycine D. Probably is responsible for the inhibitory postsynaptic potential (IPSP) in alpha motoneurons 36.The Renshaw cell functions by repetitively and rapidly transmitting an impulse to a motor neuron and causing it to become hyperpolarized. This results in A. Stimulation of the motor neuron B. Inhibition of the motor neuron C. Transmission of the impulse to other motor neurons D. “Reverse” transmission of the impulse down a sensory neuron 37.Which of the following is NOT characteristic of chemical synapses? A. Synaptic delay B. Two-way conduction C. Susceptibility to drugs D. Summation algebraically 38.Excessive circulating levels of ACTH are mainly associated with A. Accelerated bone maturation B. Cushing’s syndrome C. Cushing’s disease D. Decreased concentration of amino acids in blood 39.Pituitary secretion A. Shows a negative feedback relationship with its target organs B. If increased will usually cause target gland atrophy C. Will increase as long as target gland secretion is high D. Will decrease if levels of circulating target gland secretion are low 40.Which is not true about anterior pituitary secretion A. Is independent of CNS control from above the level of the hypothalamus B. Of only one pituitary hormone is signaled by each hypothalamic-releasing factor 5 C. Depends on a direct neural connection between the hypothalamus and the anterior pituitary D. Depends on the release of hypothalamic-releasing factors into the primary capillary plexus in median eminence Ⅱ.Explain the terms (30points, 3 points per term) 1. Cardiac output 2. Simple diffusion 3. Cardiac cycle 4. Neuroendocrine cell 5. Acromegaly 6. Synapse 7. Reciprocal inhibition 8. Ventilation-Perfusion Ratio 9. Enterohepatic Circulation of Bile Salts 10. Nephron Ⅲ.Answer the questions (30points, 10 points per question). 1. Explain why the atria are not the major pump. 2. Please describe the functional segments of a neuron. 3.What are the functions of antidiuretic hormone and aldosterone in regulation of urine formation? What parts of the renal tubules are they act on? Where are they synthesized in and where are they released from? 6 Answer sheet 7 8