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Prescription Drug Overdose In North Carolina State Health Director’s Meeting Jan 24th, 2014 Agenda • Overview & Surveillance – Dr. Steve Marshall, UNC Injury Prevention Research Center (IPRC) • Legislative Changes (S222 & S20) – Elizabeth Hudgins, Child Fatality Task Force (CFTF) • Project Lazarus/CCNC-Community Prevention – Dr. Robin Cummings, State Health Director Problem Overview • Epidemiology of the Overdose Problem • Personal Stories • What is NC doing? – Response Coordination – Local ED Surveillance of Overdose – CSRS – Research at UNC IPRC Disclosures • No financial interests or disclosures • My partner, Dr. Anna Waller, is associated with the NC-Detect system, which I will be speaking about today Definition – Prescription Drug Overdose • What is a prescription drug overdose? – Acute poisoning by prescription medication – Opioids or “narcotics” (e.g. hydrocodone, oxycodone, oxymorphone, methadone) – Benzodiazepines – Any other prescription medication • Any substance can become a poison - Dose makes the poison, not the substance Problem Overview: US Prescription Overdose Pain Management by Medication • Positives – Prescription painkillers help people manage chronic pain, greatly improve quality of life • Negatives – Patient addiction & dependence – Diversion of drugs for illicit purposes – Overdose 15,000 prescription painkiller overdose deaths annually in US 1 in 20 people (>12 yrs) used prescription pain killers for “nonmedical purposes” Enough prescription painkillers were prescribed annually to medicate every US adult around-the-clock for a month November 2011 North Carolina Poisonings Data 2000 Unintentional Poisoning and Motor Vehicle Deaths North Carolina Residents, 1999–2012 1800 Motor Vehicle/Transportation 1600 1400 1200 1000 800 Poisoning 600 400 200 0 1999 11 2000 2001 2002 2003 2004 2005 2006 National Vital Statistics System, http://wonder.cdc.gov, multiple cause dataset Source: Death files 1999-2012, State Center for Health Statistics. Analysis by Injury Epidemiology and Surveillance Unit 2007 2008 2009 2010 2011 2012 Unintentional Poisoning Deaths by Drug Type and Year: N.C. Residents, 1999-2012 800 Opioid Pain Medications 700 Cocaine 600 Heroin 500 400 300 200 100 0 1999 2000 2001 2002 2003 2004 Note: categories are not mutually exclusive Source: N.C. State Center for Health Statistics, Vital StatisticsDeaths, 1999-2012 (2012 Provisional) Analysis by Injury Epidemiology and Surveillance Unit 2005 2006 2007 2008 2009 2010 2011 2012 Unintentional Poisoning Deaths, 1999-2001 Source: N.C. State Center for Health Statistics, Vital Statistics-Deaths, 1999-2012 Analysis by Injury Epidemiology and Surveillance Unit Unintentional Poisoning Deaths, 2002-2005 Source: N.C. State Center for Health Statistics, Vital Statistics-Deaths, 1999-2012 Analysis by Injury Epidemiology and Surveillance Unit Unintentional Poisoning Deaths, 2006-2009 Source: N.C. State Center for Health Statistics, Vital Statistics-Deaths, 1999-2012 Analysis by Injury Epidemiology and Surveillance Unit Unintentional Poisoning Deaths, 2010-2012 Source: N.C. State Center for Health Statistics, Vital Statistics-Deaths, 1999-2012 Analysis by Injury Epidemiology and Surveillance Unit Personal Stories: The Polarizing Effect of Drug Abuse Deadly Pills: A National Epidemic Kristen Mascia, People Magazine 01/28/2013 Photo: New York Daily News • Joey DiBernardo Jr, 40 yr old NY firefighter • Age 36 yrs: severe occupational injuries jumping from a burning building • Cycle of chronic pain, depression, and dependence on prescribed painkillers • Expressed deep concern about dependence on medicines • Fatal overdose: combined opioid hydromorphone with antidepressant citalopram • Not a recreational drug abuser, simply someone trying to live through pain • Needed access to information on dangers of combining medicines Deadly Pills: A National Epidemic Kristen Mascia, People Magazine 01/28/2013 • Harry Cohen, 17 yr old QB, Burlington, NC • Took methadone prescribed for a family member with fibromyalgia • No reported prior history of drug abuse • Classic novice experimenting with drugs • Probably limited comprehension of interaction of dosage, tolerance, and body weight Photo: http://www.harryecohen.com/ Deadly Pills: A National Epidemic Kristen Mascia, People Magazine 01/28/2013 “Jace Flom's mom died two weeks after her birth of an overdose of prescription drugs” Photo: Grant Delin Deadly Pills: A National Epidemic Kristen Mascia, People Magazine 01/28/2013 • • • • Melanie Flom, 26 yr old mother Chronic pain from car crash injuries at age 20 Transitioned to a routine recreational drug abuser Fatal overdose event: Combined her prescribed painkillers with other prescription painkillers given to her by friends, plus alcohol Photo: Grant Delin Online comments discuss the perception of addiction as a failure of character, rather than a treatable disorder: • “This child is better off without her druggie mom” • “Addiction is a choice, not a disease” • “Addiction IS a disease, but getting help is a choice” Context for Public Health Prevention Efforts: Concerns from Pain Patients about Access to Medicine “Articles like this make it harder and harder to get the medication we need to just have a seminormal day. I, for one, do NOT abuse what is given me.” Photo: Grant Delin Online Comments from Readers on Deadly Pills: A National Epidemic People Magazine 01/28/2013 “Please don't judge those of us who rely on these medications and take them the way they are prescribed …. I have never felt high or impaired on my medication.” “I'm now 34yrs old and have had 6 MAJOR surgeries relating to different diagnoses, starting at the age of 13, I can tell you that without a doubt, I would NOT be able to function, at even a semi-normal level, without a prescription for a strong narcotic.” North Carolina’s Response: Coordinating between Partners North Carolina Injury and Violence Prevention Branch Epidemiology, Policy, Partners, Community North Carolina Comprehensive Community Approach Chronic Pain Initiative Opioid Death Task Force Policy Prescription Drug Monitoring System Poisoning Death Study Substance Abuse SAC Poisoning Workgroup Policy & Practice Research Enforcement Drug Take Back SBI & Medical Board Div. of Public Health Div. Medical Assistance Div. Mental Health/Substance Abuse North Carolina’s Response: Take Back Events Supply and Need • Expected duration of pain may be short-term – EG: 2-5 days following surgery • Dispensed quantity is often longer – EG: 30 days • Natural reluctance to throw it away, in case you “need it some day” • Result: Gradual accumulation of dangerous medicines in homes Safe Kids and Operation Medicine Drop facilitate safe disposal of medicines in NC Searchable index of community drop-off locations & community take-back events North Carolina’s Response: Realtime ED Surveillance of Drug Overdose in Your County Deaths vs. ED visits for drug overdose, NC 2011 1,222 deaths 22,992 ED visits The number of ED visits for overdose dwarfs the number of overdose deaths Average NC county has about one overdose death per month but just under one overdose ED visit per day © 2014 University of North Carolina at Chapel Hill and NC Division of Public Health, NC DHHS Unintentional Poisoning ED Visits, 2011 Source: Division of Public Health, NC DETECT-ED visit data, 2011 Analysis by Injury Epidemiology and Surveillance Unit NC DETECT coding for substance abuse, Dx and E-codes as primary Local ED surveillance data using NC DETECT NC DETECT was created in 2004 to address the need for timely detection of public health emergencies. In 2005, under NC General Statute § 130A-480, all 24/7, acutecare, hospital-affiliated EDs were required to submit ED visit data every 12 hours. In addition to ED visit data, NC DETECT captures data from the Carolinas Poison Center (CPC), the Pre-hospital Medical Information System (PreMIS), four VA Medical Center EDs, and select urgent care centers. © 2014 University of North Carolina at Chapel Hill and NC Division of Public Health, NC DHHS NC DETECT Overdose Surveillance • 4 reports currently available on Hot Topics Dashboard & Custom Event Line Listing • 9 additional to be added soon • Graphs, line listing information available – ZIP code maps for select reports by June © 2014 University of North Carolina at Chapel Hill and NC Division of Public Health, NC DHHS Dashboard of Overdose Reports For Your County © 2014 University of North Carolina at Chapel Hill and NC Division of Public Health, NC DHHS Opioid OD Graph from NC DETECT © 2014 University of North Carolina at Chapel Hill and NC Division of Public Health, NC DHHS © 2014 University of North Carolina at Chapel Hill and NC Division of Public Health, NC DHHS Report on Opioid Analgesic Overdose ED Visits for Your County Age Sex Chief Group Complaint Triage Note XX XX Overdose Chief Complaint Subjective: Per EMS, wife last saw normal, woke up and found him on the couch with agonal breathing. When EMS arrive, gave Narcan. Patient awake and cooperative at this time. XX XX DRUG OVERDOSE denies suicide, crushed and injected XXX XX XX XX XX DRUG OVERDOSE OVERDOSE © 2014 University of North Carolina at Chapel Hill and NC Division of Public Health, NC DHHS pt states took 5 XXXX around XX. pt appears sleepy. pt A+O x4. pt denies SI states she was hurting in neck and back. EMS states …. per ems pt from home poss od on ambien, xanax and neurontin, ems sts blood sugar on scene, ems sts pt was last found normal approx XXX © 2014 University of North Carolina at Chapel Hill and NC Division of Public Health, NC DHHS http://www.ncdetect.org/ Account Request © 2014 University of North Carolina at Chapel Hill and NC Division of Public Health, NC DHHS NC DETECT Training • Contact Jenna Waggoner or Amy Ising for customized Web-based or in-person training – [email protected] – [email protected] (919) 966-8853 • NC DETECT User Guide available online • Help icon on dashboard reports © 2014 University of North Carolina at Chapel Hill and NC Division of Public Health, NC DHHS NC Controlled Substance Reporting System (CSRS) Controlled Substance Reporting System • Allows a healthcare provider to review complete prescription history for a patient – Including prescriptions from other providers • Excellent idea, but not used by all providers – Legislative committees to study the CSRS – Legislative bills to strengthen the CSRS – Invaluable information for public health monitoring and analysis of provider prescribing Source: Substance Abuse and Mental Health Services Administration. Results from the 2012 National Survey on Drug Use and Health: Summary of National Findings. Rockville, MD: Substance Abuse and Mental Health Services Administration, Office of Applied Studies; 2013. UNC IPRC Overdose Research UNC IPRC Research • Funding: – CDC, NIJ, Kate B. Reynolds Foundation • Research Topics include Evaluating: – ED protocols for managing pain patients – Effectiveness of the CSRS in NC and similar programs nationally – Project Lazarus and Chronic Pain Initiative – Surveillance Methodologies – Identification of Select Health Care Providers – Medicaid’s Lock-In Program Acknowledgements • IVPB / DPH: • Scott Proescholdbell • NC-Detect / DPH: • Katie Harmon, Amy Ising, Lana Deyneka, many others • UNC: • Chris Ringwalt, Mariana Garrettson, Nabarun Dasgupta • Others: • Fred Brason, Kay Sanford Thank you! Steve Marshall, PhD Injury Research Prevention Center (IPRC) & Gillings School of Global Public Health University of North Carolina-Chapel Hill [email protected] injuryfreenc.org iprc.unc.edu