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Outlines of course content in Certificate of Advance Study in Advanced Contact Lenses and Understanding of Corneal and other anterior segment Mechanisms in Disease and Surgical Management. Module 1 Course 1 Details of Module Certificate of Advance Study in Advanced Contact Lenses and Understanding of Corneal and other anterior segment Mechanisms in Disease and Surgical Management. Course Title: Advanced Contact Lens with in-depth understanding of Rigid Gas Permeable Lenses Instructor: Mr. Michael Bärtschi Mr. Michael Wyss Dr. Nina Mueller Approximate hours of lecture: ~ 20 hours Approximate hours of workshop: ~ 10.5 hours To provide an understanding and working knowledge of complex and specialty contact lens designs for normal and irregular eyes. Also, to provide an understanding of complications arising from contact lens wear and their clinical management 1. Rigid Gas Permeable Contact Lenses Rigid Lens Materials, Manufacturing and Rigid Lens Design Corneal Topography, Techniques and interpretation Rigid Lens Fit Characteristics Rigid Lens Fluorescein Patterns Rigid Lens Parameter Changes Optics and Aberrations 2. Contact lens care systems Basics Silicon Hydrogel lenses Scleral lenses Hybrid contact lenses 3. Contact Lenses for Astigmatism Stabilization systems for soft contact lenses Engraving and markings Fitting procedures Understanding stabilization of Front Surface Toric Rigid Lenses Understanding of stabilization of Back Surface Toric Rigid Lenses Understanding of stabilization and working mechanism of Bitoric Rigid Lenses Understanding of over refraction measurement and how to determine the final power 4. Contact Lenses for Presbyopia Demography and Economy Features of a presbyopic eye Monovision and modified monovision Aplante systems Diffractive systems 5. Fitting the Irregular Cornea Corneal irregularity Regular versus irregular astigmatism Keratoconus and fitting Irregular astigmatism and fitting Corneal transplants: keratoplasty Contact lens for aphakic eyes Post-Refractive surgery contact lenses Contact lenses for therapeutic purposes with cases Contact lenses for prosthetic reasons 6. Orthokeratology and Myopia Control Modern Orthokeratology lens design and history of Orthokeratology Orthokeratology theory and research, Myopia control Patient selection and fitting Results, complications and complication management in Orthokeratology 6. Contact lenses for Infant and Children Aphakia with contact lens and bifocal glasses RGP and myopia progression 7. CL complications, gradings and management Soft lenses RGP lenses Extended and constant wear Final Discussion Workshops Fluorescein interpretation Topography and Pentacam interpretation RGP fitting Workshop on astigmatism Workshop on Presbyopia Symergeyes Scleral lenses RGP for Keratoconus and keratoplasty Module 2 Details of Module Certificate of Advance Study in Advanced Contact Lenses and Understanding of Corneal and other anterior segment Mechanisms in Disease and Surgical Management. Course Title: Therapeutic Pharmaceutical application to anterior segment diseases Instructor: Dr. Anthony Cavallerano Lecture hours : ~ 12 hours 1. Ocular Microbiology/Cytology A review techniques and interpretation of ocular surface stains, smears, cultures, and sensitivities will be presented. The role of laboratory testing in treating anterior segment infectious disease and detail 2. Infectious and Non -Infectious Eyelid Disease and Adnexa Treatment of various forms of blepharitis, differentiating between anterior and posterior lid inflammation Complications of blepharitis, specifically exposure keratitis and corneal non - infectious ulcers and infiltration. Meibomitis and the relationship of lid gland inflammation and infection, pre-septal and orbital cellulitis, masquerade syndrome, pyogenic granulomas, and acne rosacea Parasitic infestation of the lids and lashes as well as viral lid lesions The emphasis is on the therapeutic treatment for each of the above disorders. Understand the role of topical/systemic medications and surgical procedures for lid disorders. 3. Conjunctivitis Why conjunctivitis manifests. differential diagnosis of the red eye and the clinical presentation of the various forms of conjunctivitis in order to choose the appropriate therapy -bacterial -viral -allergic Classifications of conjunctivitis based upon clinical signs and symptoms Epidemiological profiles of certain organisms The clinical role of cultures, stains and sensitivities The manifestation of viral conjunctivitis and treatment options available The role of steroids in treating conjunctiva disorders The stepwise treatment protocol for treating allergic conjunctivitis. A knowledge of the organisms precipitating conjunctiva infection and the application of appropriate pharmacological agents The role of systemic agents in treating conjunctiva infections. 4. Keratitis Keratitits and affect on other tissues structures Mild to severe epitheliopathy Corneal Ulcers infectious vs non infections - etiology - role of contact lenses - other conditions predisposing to ulcers - clinical presentations -treatment regiment Infiltrative keratitis - etiology - role of contact lenses - clinical presentations - treatment regiment Herpes Simplex - epithelial - stromal - clinical manifestations of metaherpetic diseases and complications Herpes Zoster Adenovirus Treatment options with use of keratitis and ulcers -topical anti - inflammatory agents -antibiotics -fortified antibiotics. Distinction between herpes simplex and herpes Zoster -treatments specific to each -short term and long term complications -topical antiviral agents and their side effects, oral anti-virals Evidence based medicine for treatment of infections Ocular emergencies Details of Module Course Title: Ocular Physiology Principles related to Anterior Segment of the Eye Instructor: Dr. Jim Mertz Approximate hours of lecture: 12.0 hrs To teach students all the required cell physiology, biochemistry and molecular biology necessary to understand its usefulness in the diagnosis and treatment of anterior segment disease, and to provide the needed background to support the use of available and future diagnostic and therapeutic pharmaceuticals. To interrelate the basic sciences to the clinical application of anterior segment pathology 1.Tear physiology/hypersensitivity/immunology 2. Lids And Conjunctiva Ocular Anaphylaxis, Hay Fever 3. Function Fluid dynamics –steady state Blinking Composition Secretion Excretion forces New research Protection Mechanisms of the Body Protective Mechanisms of the External Eye How Infectious Agents Infect Elude protective barriers (lids and lashes) Attach to epithelial surface Cause Injury Protective Possibilities Dry Eye Classification: gland, etiology, severity Antibacterial Substances in Tears Contact Lens Coatings s IgA Elements of the Immune Response - a review Changing Definitions of Anaphylaxis - the historical perspective Ways to release Mast Cell Contents - mimics of allergy Mast Cell Anatomy - the fast and slow responses The Mediators - rational drug design Ocular Anaphylaxis: Where-MC location, Timing-MC anat Diagnosis: a review Treatment: now and future Cornea and its Response to Injury Function, morphology and innovation Metabolism, function and transparency, Drug permeability, injury and response 4. Lens physiology IntroductionBasic Properties General Anatomy Relative To Glaucoma And Cataract Variables Affecting Transparency (Cataract) Deformability Considerations (Presbyopia) Refraction Considerations (Age, Cataract, Diabetes) Protection: ARMD Lens: Unique Proteins and Lens Metabolism needed for Optical Clarity and Protection from Oxidative Stress Statement Of Problem: With so much protein in the lens (i.e., more than skin) why is it transparent, and how is the transparency maintained? Protein Concentration (chaperones) The Pump Leak System (Sorbitol and Aldol Reductase inhibitors Oxidative Stress Major Lens Proteins: a. The Crystallins and Albuminoid b. The chaperones, alpha crystallin c. The gap junction protein – connexions and the aqueous pores, aqueporin (MIP) d. The pumps: Na, K, ATPase e. The enzymes of metabolism (ATP and NADPH production) Some pathways to Cataract a. Sunlight - do vitamins and trace metals protect? b. Posterior inflammations - PMN's and the respiratory burst c. Diabetes - the use of aldol reductase inhibitors. d. Diabetes - Advanced Glycation End Products (AGE's) - aspirin? Lens -- Lecture #3 Ageing, Disruptions, Cataract Ageing Disruptions Consequences of Pump Interference Factors Interfering with Pumps Osmotic Interferences (gradients) Leak Interferences o Cataract Clinical Classification Time Sequence Nuclear Brunescence vs. posterior yellowing) Module 3 Details of Module Certificate of Advance Study in Advanced Contact Lenses and Understanding of Corneal and other anterior segment Mechanisms in Disease and Surgical Management. Course Title: Anterior segment problems related to dry eye and contact Lenses. Instructor: Dr. Caroline Blackie Approximate hours of lecture: ~ 10 hours Approximate Hours of workshop: ~ 2 hours 1. Tear Film Disorders and Dry Eye for non contact lens and contact lens wearers Review of anatomy of structures, physiology of tear film production, dynamics of tear film surfacing and eliminations Emphasis is placed on the commonly occurring anomalies and abnormalities. The tests used to determine tear film sufficiency and stability are discussed as well as the relative merits and practical application of each. Management strategy for each type of tear film deficiency Future of dry eye treatments Meibomian gland dysfunction and its related affect Affect of tear film disorders and dry eye on contact lens wearers Affects of lids and dry eye disorders 2. Use of corneal topography in decision making 3. Ocular surface evaluation workshop Details of Module Course Title: Refractive Surgery and other corneal surgical techniques Instructor: Dr. J. Edeling: South Africa Approximate hours of lecture: ~ 6 hours Refractive surgery 1. Understanding of wavefront technology and optics of laser 2. Patient choices for refractive surgery: Different techniques, pros and cons 3. Pre –operative management for patients 4. Post operative management post refractive surgery treatment 5. Complications of refractive surgery and management/treatment options 6. Successes of refractive surgery 7. Future development in refractive surgery Corneal surgical techniques including pre and post surgical care 1. Corneal transplants 2. Pterygium removals and grafting 3. Future in corneal repair Lens and cataract: 1.Update on cataract surgery and techniques 2. Implants (contact lens) above crystalline lens Details of Module Course Title: Overview of relevant general and ocular Pharmacology and therapeutic drugs available on South African Market Instructor: Dr. George Muntingh ( South Africa) Approximate hours of lecture: ~ 6 hrs No info for Muntingh!!!!!! Not on Bina’s schedule Module 4 Details of Module Certificate of Advance Study in Advanced Contact Lenses and Understanding of Corneal and other anterior segment Mechanisms in Disease and Surgical Management. Course Title: Advanced Anterior Segment Disease with emphasis in Cornea. Instructor: Dr. William Sleight Approximate hours of lecture: ~ 20.0 hrs LONG DISTANCE LEARNING MODULE Time for completion: 90 days maximum The Ocular Disease Diagnostic Tutor (ODTT)is a software tutorial program that is designed to train clinicians to recognize and correctly describe various tissue changes related to ocular disease. The program is unique in its clinical pathologic approach to applying the correct terminology to common and uncommon ocular diseases. The ODDT trains clinicians to recognize and use terminology correctly. The correct understanding and application of clinicalpathologic terminology is the foundation of differential diagnosis and understanding the underlying pathologic changes reflected by the clinical presentation. The ODDT exposes clinician to common and uncommon conditions and requires mastery of both content and cognitive interactive exercises. It compliments the teaching of conditions already covered in the curriculum by its unique emphasis in recognizing and properly applying critical clinical observations to these diseases. Furthermore, it adds to the curriculum by covering in detail rarer conditions which are not handled in detail typically in an existing curriculum. Limbal thinning Nomenclature exercises Furrow degeneration, Dellen, Pellucid Marginal Degeneration, Rheumatoid furrow, Systemic Lupus Furrow Degeneration, Terrien’s Marginal Degeneration Diagnostic cases Terrien’s Marginal Degeneration, Pellucid Marginal Degeneration, Dellin, Peripheral Ulcerative Keratitis, Systemic Lupus Erythematosus Reasoning cases Blebitis, PUK Topic file support and interactive quizzes Furrow degeneration, Dellen, Pellucid Marginal Degeneration, Rheumatoid furrow, Systemic Lupus Furrow Degeneration, Terrien’s Marginal Degeneration Limbal Inflammation Nomenclature exercises Atopic keratoconjunctivitis, Vernal Keratoconjunctivitis, Superior Limbic Keratoconjunctivitis, Phlyctenulosis, Mooren’s Ulcer, Terrien’s Marginal Inflammation, Sterile Marginal Infiltrates, Roseacea keratitis, Peripheral Ulcerative Keratitis (RA, PAN, WG, SLE) Diagnostic cases CL-SLK, VKC, Rosacea, Sterile Marginal Infiltrates, Phlyctenulosis, Pingueculitis Reasoning cases SLK, Blepharo-kerato-conjunctivitis Topic file support and interactive quizzes Atopic keratoconjunctivitis, Vernal Keratoconjunctivitis, Superior Limbic Keratoconjunctivitis, Phlyctenulosis, Mooren’s Ulcer, Terrien’s Marginal Inflammation, Sterile Marginal Infiltrates, Roseacea keratitis, Peripheral Ulcerative Keratitis (RA, PAN, WG, SLE)