Survey
* Your assessment is very important for improving the workof artificial intelligence, which forms the content of this project
* Your assessment is very important for improving the workof artificial intelligence, which forms the content of this project
Chapter 25-1 The Digestive System Functions of the digestive system LaPointe Spring ‘12 Slide # 2 • Ingestion • Mechanical processing (mastication, propulsion, mixing) • Digestion (Chemical digestion) • Secretion • Absorption • Elimination (defecation) The Digestive system includes (but not limited to): • The muscular digestive tract (alimentary tract) • esophagus • stomach • small intestine • large intestine • Various accessory organs (e.g.) • salivary glands • exocrine pancreas • liver • gall bladder LaPointe Spring ‘12 Slide # 3 Components of the Digestive System LaPointe Spring ‘12 Slide # 4 Peritoneum LaPointe Spring ‘12 Slide # 5 • Serous membrane that lines the peritoneal cavity • parietal peritoneum • visceral peritoneum • develops into the mesentery that holds and supports the digestive organs Mesentery and the peritoneum LaPointe Spring ‘12 Slide # 6 • Mesenteries • Sheets of serous membranes that support portions of the digestive tract • Greater omentum lies anterior to abdominal viscera • Provides padding, protection, insulation, and energy reserves • Lesser omentum lies between the stomach and the liver. • Stabilizes the stomach and provides support for blood vessels entering and leaving the stomach Mesentery LaPointe Spring ‘12 Slide # 7 • Falciform ligament supports and stabilizes the liver. • Mesocolon - mesentery associated with the large intestine. • transverse mesocolon • sigmoid mesocolon • Retroperitoneal organs • duodenum • pancreas • rectum Mesenteries LaPointe Spring ‘12 Slide # 8 Mesenteries LaPointe Spring ‘12 Slide # 9 Histology of the digestive tract LaPointe Spring ‘12 Slide # 10 I. Mucosa lines the inside of the digestive tract • mucous epithelium • Lamina propria - areolar tissue, nerves, blood vessels, lymphatics, MALT system, etc, • muscularis mucosae - thin layer of smooth muscle cells Mucous Epithelium 1. Stratified squamous epithelium • (mouth, oral pharynx, esophagus, anus) 2. Simple columnar epithelium • (most of the tract) 3. Enteroendocrine cells 4. Goblet cells Moistened by glandular secretions LaPointe Spring ‘12 Slide # 11 Histology of the digestive tract LaPointe Spring ‘12 Slide # 12 II. Submucosa • Layer of irregular connective tissue • exocrine glands • large blood vessels and lymphatic vessels • Meissner’s plexus - (submucosa plexus) network of sensory neurons, parasympathetic ganglionic neurons, sympathetic nerves • mainly controls secretions, mucosa muscle contraction Histology of the digestive tract LaPointe Spring ‘12 Slide # 13 III. Muscularis externa • Two layers of smooth muscle arranged in a circular and a longitudinal layer (in most parts of the tract) • myenteric plexus - a second nerve plexus • mainly coordinates smooth muscle contraction of the muscularis externa IV. Serosa (visceral peritoneum) • Serous membrane covering most of the muscularis externa • Adventitia- oral cavity, pharynx, esophagus, rectum Structure of the Digestive Tract LaPointe Spring ‘12 Slide # 14 Also see fig 25.2 Marieb Figure 23.6 G.I. Reflexes • Short reflexes • stay within the GI tract • myenteric and submucossal networks • Long reflexes • go to and from the CNS • mainly vagovagal reflexes LaPointe Spring ‘12 Slide # 15 Movement of material in the digestive tract LaPointe Spring ‘12 Slide # 16 • Visceral smooth muscle show rhythmic cycles of activity • Pacemaker cells • Peristalsis • Waves that move a bolus • Segmentation (mixing) • Churn and fragment a bolus Peristalsis LaPointe Spring ‘12 Slide # 17 1. Contraction of circular muscle behind bolus / relaxation in front of bolus. 2. Contraction of longitudnal muscle. (shortens the segment) 3. Series of contractions of circular muscle (pushes bolus forward) Figure 23.3 Peristalsis LaPointe Spring ‘12 Slide # 18 Mixing: Segmental contraction LaPointe Spring ‘12 Slide # 19 Control of the digestive system LaPointe Spring ‘12 Slide # 20 • Movement and digestion of materials are controlled by: • Neural mechanisms • Parasympathetic and local reflexes • short or enteric reflexes • Long reflexes - CNS control • Hormonal mechanisms • Enhance or inhibit smooth muscle contraction and gland secretion • Local mechanisms • Coordinate response to changes in pH or chemical stimuli • activate both neural and hormonal responses Regulation of Digestive Activities endocrine LaPointe Spring ‘12 Slide # 21 b l o o d Figure 23.4 Oral or buccal cavity LaPointe Spring ‘12 Slide # 22 • Functions include: • Ingestion • Analysis of material before swallowing • Mechanical processing by the teeth, tongue, and palatal surfaces • Lubrication • Limited digestion Oral cavity • Lined by oral mucosa • Roof of cavity = hard and soft palates • Floor of cavity = tongue • Cheeks form the lateral walls • Uvula guards opening to pharynx (Fauces) LaPointe Spring ‘12 Slide # 23 The Oral Cavity LaPointe Spring ‘12 Slide # 24 The tongue LaPointe Spring ‘12 Slide # 25 • Primary functions include: • Mechanical processing • Assistance in chewing and swallowing • Sensory analysis by touch, temperature, and taste receptors • Papillae • fungiform • cicumvallate • foliate Tongue movements LaPointe Spring ‘12 Slide # 26 • Skeletal muscle • intrinsic muscles • extrinsic muscles • lingual frenulum - mucous membrane attachment • Innervated by the hypoglossal nerve Salivary glands (three pairs) LaPointe Spring ‘12 Slide # 27 • Parotid glands • parotid ducts empty at level of 2nd upper molar • salivary amylase • serous gland - watery saliva • Sublingual glands • numerous ducts along the lingual frenulum • mucous and serous secretions (see fig 25.10) • salivary lipase • Submandibular glands • ducts along the lingual frenulum posterior to the teeth • salivary amylase Saliva LaPointe Spring ‘12 Slide # 28 • Functions include: • Lubrication, moistening, and dissolving • Initiation of digestion of complex carbohydrates • Watery solution containing electrolytes, buffers, enzymes glycoproteins, and antibodies (IgA) • salivary amylase, (ptyalin or alpha amylase) • salivary lipase • lysozyme - weak antibacteria substance • IgA The Salivary Glands LaPointe Spring ‘12 Slide # 29 Marieb Figure 23.9 Eruption of teeth LaPointe Spring ‘12 Slide # 30 • 20 primary teeth - deciduous teeth • 32 teeth of secondary dentition - permanent teeth • incisors (8) • cuspids (canine teeth) (4) • bicuspids (premolars) (8) • molars (8-12) • (depending on how many wisdom teeth come in) Primary and Secondary Dentation LaPointe Spring ‘12 Slide # 31 Numbering of Teeth LaPointe Spring ‘12 Slide # 32 Teeth • Function in mastication of bolus • Contact of occlusal surfaces • Contain three layers • Enamel covering crown • Dentin forms basic structure • pulp cavity • contains blood vessels and nerves • Root coated with cementum • Periodontal ligaments hold teeth in alveoli LaPointe Spring ‘12 Slide # 33 Teeth LaPointe Spring ‘12 Slide # 34 The pharynx LaPointe Spring ‘12 Slide # 35 • Common passageway for food, liquids, and air • nasopharynx, oropharynx, and laryngopharynx • Lined with stratified squamous epithelium • Pharyngeal muscles assist in swallowing • Pharyngeal constrictor muscles- push food toward the esophagus • Palatal muscles - elevate the soft palate, move the uvula Read book for swallowing (deglutition) (see fig 25.11) The esophagus LaPointe Spring ‘12 Slide # 36 • Carries solids and liquids from the pharynx to the stomach • Begins at C6 • Passes through esophageal hiatus in diaphragm • The wall of the esophagus contains 4 layers - mucosal, submucosal, muscularis layers, & adventitia • upper esophageal sphincter (skeletal muscle) • lower esophageal sphincter (smooth muscle) • not true sphincter muscles but regions that function in that capacity Histology of the esophagus LaPointe Spring ‘12 Slide # 37 • Nonkeratinized, stratified squamous epithelium • Folded mucosa and submucosa • mucosa muscularis has irregular layer of smooth muscle • Submucosa contains esophageal glands • mucous glands • thick mucous Histology of the esophagus • Muscularis externa • top 1/3 skeletal muscle • middle 1/3 mixed skeletal and smooth muscle • bottom 1/3 smooth muscle • Lacks serosa • Anchored by an adventitia LaPointe Spring ‘12 Slide # 38