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PATIENTGUIDE
FOR
TRYTONSIDEBRANCHSTENT ®
Indications,contraindications,warningsandinstructionsforusecanbefoundinthelabeling
suppliedwitheachproduct.CAUTION:Federal(U.S.A.)lawrestrictstheseproductstosaleby
orontheorderofaphysician.
TRYTONSideBranchStent®isaproductofTRYTONMedicalInc.
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Patient Guide, TRYTON Side Branch Stent
PATIENTINFORMATIONGUIDE.............................................................................................................................................3
CORONARYARTERYDISEASE(CAD)....................................................................................................................................4
WHATISCAD?....................................................................................................................................................................................................4
WHATARETHESYMPTOMSOFCAD?..............................................................................................................................................................4
TREATMENTOFCAD..........................................................................................................................................................................................5
CORONARYARTERYSTENTS..............................................................................................................................................................................6
TRYTONSIDEBRANCHSTENT®.............................................................................................................................................6
WHENTHETRYTONSTENTSHOULDNOTBEUSED(CONTRAINDICATIONS)........................................................7
POTENTIALADVERSEEVENTSASSOCIATEDWITHTHETRYTONSIDEBRANCHSTENT...................................8
THETRYTONCLINICALTRIALS.............................................................................................................................................9
YOURCORONARYSTENTPROCEDURE.............................................................................................................................10
HOWDOIPREPAREFORMYPROCEDURE?.................................................................................................................................................10
YOURTRYTONSIDEBRANCHSTENTPLACEMENTPROCEDURE.............................................................................10
IMMEDIATELYAFTERPROCEDURE.................................................................................................................................................................12
TAKEALLMEDICATIONSASINSTRUCTED....................................................................................................................................................12
FOLLOW-UPCARE.............................................................................................................................................................................................13
KEEPYOURPATIENTIMPLANTCARDHANDY.............................................................................................................................................13
MRIINFORMATION..........................................................................................................................................................................................13
FREQUENTLYASKEDQUESTIONS......................................................................................................................................14
GLOSSARY...................................................................................................................................................................................15
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PATIENTINFORMATIONGUIDE
YouhaverecentlyhadaTRYTONSideBranchstentimplantedinthecoronaryarteriesof
yourheart,oryouhavecoronaryarterydiseasethatmaybetreatedwithaTRYTONSide
BranchStent.Thefollowinginformationisimportantforyoutoknow,includingthepossible
risksassociatedwithhavingastentimplantalongwithmedicationrecommendationsand
questionsyoumayhaveaboutyourstent.
IfyouhaveanyquestionsabouttheTRYTONSideBranchStentorthestentingprocedure
afteryoureadthisbooklet,besuretoaskyourphysician.
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CORONARYARTERYDISEASE(CAD)
WhatisCAD?
CADisthemostcommonformofheartdisease.Itisaconditionthatoccurswhenthe
arteriesthatsupplyoxygen-richbloodandnutrientstotheheartmusclebecomenarrowed
orblockedbyagradualbuild-upofplaque.Plaqueismadeupoffattydeposits(cholesterol),
whitebloodcells,calcium,andothersubstancesthatcollectovertimeinthewallofa
coronaryartery.Thisprocessiscalledatherosclerosis.Astheplaquenarrowstheopening
(lumen)ofacoronaryartery,itcanlimitbloodflowtotheheartmuscle.
Source:
https://commons.wikimedia.org/wiki/File:Blausen_0257_CoronaryArtery_Plaque.png
WhataretheSymptomsofCAD?
TwocommonsymptomsofCADarechestpain(alsoknownasangina)andshortnessof
breath,whicharecausedbythereductionofbloodflowtotheheartmuscle.Ifplaque
build-updoesnotreducebloodflowexcessively,theremaybenosymptomsatrest,but
symptomssuchaschestheavinessorpressuremayoccurwithexerciseorstress.Aheart
attack(myocardialinfarction)canoccurifthearterysuddenlybecomescompletely
blocked,usuallybyabloodclotthatformsoverruptured(broken)plaque.Heartattacks
causepermanentdamagetotheheartmuscleandcanalsoleadtosuddendeath.
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CADsymptomsthatpatientsmayexperienceare:
• Paininthejaworneck
• Painradiatingtothearmsorback
• Heartburn
• Nausea
• Vomiting
• Heavysweating
Whenbloodflowissignificantlyreduced,andtheheartmuscledoesnotreceiveenough
bloodtomeetitsneeds,severesymptomssuchaschestpain(angina),heartattack
(myocardialinfarction),orheartrhythmdisturbances(arrhythmias)mayoccur.
TherearesomepatientswhoreportnosymptomsofCAD.Itispossibletohaveaheart
attackwithoutexperiencinganysymptoms.
RecentresearchhasshownthatsomewomenexperiencedifferentCADsymptomsfrom
menandarelesslikelythanmentoreportchestpain,heavinessinthechest,orchest
discomfortduringaheartattack.Womenmaynoticeotherearlysymptoms,suchas
unusualtirednessorsleepdisturbancesuptoonemonthpriortoaheartattack.These
differencesinsymptomsmaycausesomewomentodelayseekingtreatment.
TreatmentofCAD
CADcanbemanagedbyacombinationofchangesinlifestyle(eatingahealthydietthatis
lowinsaturatedfat,regularexercise,andquittingsmoking)andmedicaltreatment.Your
treatmentmayincludemedicationstorelieveyourchestpainand/ortoexpandthe
coronaryarteries,increasingbloodflowtoyourheart.However,becausemedicinealone
maynotadequatelyrelieveyoursymptoms,youmayneedfurthertreatments,whichmay
includebypasssurgery,balloonangioplasty,andstenting.Yourphysicianhasdetermined
thatuseofacoronarystentisthebesttreatmentforyou.
Inabout15%ofpatients,theblockageinamajorheartarteryalsoinvolvesablockage
withinasidebranchthatcomeoffofthatmajorheartartery.Thisisreferredtoasa
bifurcationlesion.Bifurcationlesionsaremorecomplexthannon-bifurcationlesions,and
theirtreatmentwithangioplastyandstentsisassociatedwithhigherrisksofheartattack
andtheneedforarepeatproceduretotreatare-narrowedheartvessel.
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CoronaryArteryStents
Coronaryarterystentsaredevices(smallmetallicmeshtubes)thatareplacedovera
ballooncatheteranddeliveredtothenarrowedportionofacoronaryartery.Theballoonis
usedtoexpandthestent.Thestentpressesagainstthenarrowedvesselwall,holdingthe
vesselopen.Thismakesawiderchanneltoimprovebloodflowtotheheartmuscle.This
maybefollowedbyrepeatballooninflationswithinthestenttoachievetheresultdesiredby
yourdoctor.Oncetheballoonhasbeendeflatedandwithdrawn,thestentstaysinplace
permanently,holdingthecoronaryarteryopen.Theinnerliningofthearterygrowsover
thesurfaceofthestent,makingthestentapermanentpartofyourartery.
Coronaryarterystentsarelessinvasivethanbypasssurgery.Stentinginvolvesashorter
hospitalstay–usuallyonetothreedays–andfasterrecoverythansurgery.However,the
coronaryarterymayre-narrow(calledrestenosis)insomepatientswhoreceivestents(instentrestenosis),duetothebuild-upofscartissuewithinthestentleadingtonarrowingof
thestentlumen.Thismayrequirefurthertreatments,suchasrepeatangioplastyand/or
bypasssurgery,toreopenthearteryandincreasebloodflowtotheheart.
TRYTONSIDEBRANCHSTENT®
TheTRYTONSideBranchStentisastentmadefromcobaltchromiumalloy.Cobalt
chromiumisabiocompatiblemetalspecificallydevelopedforcoronarystents.Thestentis
flexibleandwasspeciallydesignedtoallowittofittheshapeofablockedmajorheartartery
thatalsohasablockageinasidebranch(bifurcationlesion).TheTRYTONSideBranchStent
isdeliveredtothearteryonaballoondeliverycatheterandwillbeusedwithanother
company’sdrug-elutingstent(DES)thatyourdoctorwillimplantinoneofyourmainheart
arteries.
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DiagramoftheTRYTONSideBranchStentmountedon
DeliveryBalloon
Mid Markers
Proximal Marker
Distal Marker
WHENTHETRYTONSTENTSHOULDNOTBEUSED(CONTRAINDICATIONS)
•
•
•
•
•
•
•
•
•
•
•
•
•
•
•
•
Ifyourarteryiscompletelyblocked
Ifyourphysicianseesmoderatetoseverecalciumdepositsintheartery
Ifyourarteryisseverelycurvedmakingitdifficulttogettotheblockage
Ifyourphysicianseesbloodclots/thrombusblockingtheartery
Ifyourphysicianfeelshe/shecannotcompletelyinflatetheangioplastyballoon
Notinflatingtheangioplastyballooninthemainbranchandsidebranchpriorto
TRYTONstentplacement
PlacementofTRYTONstentalone,withoutamainbranchstent
PoorflowbeyondthestentimplantationsiteduetosevereCAD
Anuntreatedsignificant(>50%)blockagebeforeorafterthemainbranchorside
branchtargetlesion
Ifyourheart’spumpingstrengthisverypoor
Ifyouhaveimpairedkidneyfunction
Ifyouhaveabnormalbloodtestsindicatingbleedingdisorders,increasedriskof
infections,orknownorsuspectedliverdisease
Ifyouarearecipientofhearttransplant
Ifyouhaveanallergyorhypersensitivitytocobalt-chromiumorstructurallyrelatedcompounds,cobalt,chromium,nickel,ortungsten
Ifyourphysicianplanstoperformrotationalatherectomy(useofadevicetobreak
upplaqueinsidetheartery)
Ifyourphysiciandecidesyoushouldnotreceiveadrug-elutingstentbecauseyou
cannottaketherecommendedbloodthinninganti-plateletmedications
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POTENTIALADVERSEEVENTSASSOCIATEDWITHTHETRYTONSIDEBRANCH
STENT
TherisksofusingtheTRYTONSideBranchStentaresimilartothosethatareassociated
withotherstandardheartstentprocedures.Astentthatbecomesblockedbyabloodclot
mayleadtoaheartattack,theneedforurgentbypasssurgery,deathortheneedfor
anotherangioplastyprocedure.Evenwithsuccessfulstentimplants,thereisachanceofrenarrowing(restenosis)ofyourcoronaryartery.Thismayrequirefurthertreatments,such
asrepeatangioplastyand/orbypasssurgery,toincreasebloodflowtotheheart.Therisks
fromusingballooncatheterstoimplantstentsmaybeseriousenoughtorequiresurgeryor
causedeath.
Otherrisksassociatedwithballoonangioplastyandheartstentimplantationprocedures
include,butarenotlimitedto:
• Abruptvesselclosure(suddenclosureofthevessel)
• Acutemyocardialinfarction(heartattack)
• Aneurysm(weakeningofaportionofthewallofthebloodvessel)
• Arrhythmia,includingventricularfibrillation(irregularheartbeat)
• Arteriovenousfistulas(abnormalconnectionbetweentwovesselsthat
normallydonotconnect
• Coronaryarteryspasm
• Coronaryvesseldissection(tearwithinthebloodvesselwall),perforation,or
injury
• Death
• Drugreactionsorallergicreactionstocontrastmedium
• Emboli(air,piecesofdevices,fragmentsofclot,orfragmentsofplaquethat
canblockbloodvesselscausingtissueinjury)
• Fever
• Hematoma(tissueswellingcausedbyabloodclot)orhemorrhage(bleeding)
• HypotensionorHypertension(decreasedorincreasedbloodpressure)
• Hypersensitivity(allergic)reactions
• Infection
• Myocardialischemia/Angina,(chestpainduetodecreasedoxygensupplyto
theheart)
• Non-heart-relatedchestpain
• Pseudoaneurysm(enlargementofabloodvesselduetoaninjurytotheblood
vesselwall)
• Restenosisofthetreatedvessel(re-blockageofthebloodvesselfollowingthe
procedure)
• Stentmisplacementormigration(movementofthestentfromwhereitwas
placed)
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•
•
•
•
Stroke
Thrombosis(bloodclotwithinabloodvessel)
Occlusion(blockage)ofacoronaryarteryorheartbypassgraft
Anginapectoris(chestpaincausedbyinadequatebloodflowtotheheart)
THETRYTONCLINICALTRIALS
ThesafetyandeffectivenessoftheTRYTONSideBranchStentwasestablishedintwo
researchstudies:theTRYTONPivotalRandomizedClinicalTrial(RCT)andtheExtended
Access(EA)ConfirmatoryStudy.
IntheTRYTONPivotalRCTStudy,704patientswithCADinvolvingbifurcationlesions
wererandomlydividedintotwogroupsfortreatment.Onegroupof355patientswas
assignedtoreceivetheTRYTONStenttotreattheblockedsidebranch,andtheother
groupof349patientswastobetreatedwithballoonangioplastyoftheblockedside
branch.Bothpatientgroupsalsoreceivedanapproveddrug-elutingstenttotreatthe
blockageinthemajorvessel.At9monthsaftertheprocedure,patientsintheTRYTON
grouphadahigherrateofheart-relatedcomplications(16.7%)comparedtothe balloon
angioplastygroup(12.6%),butmostofthedifferenceinthecomplicationratebetween
thetwogroupswasduetoverysmallheartattacksoccurringatthetimeofthe
procedure.Importantly,whendoctorsusedtheTRYTONstentinsidebranchheart
vesselsthatweresuitedtothesizerequirementsoftheTRYTONStent,therateofheartrelatedcomplicationsat9monthswaslowerintheTRYTONgroup(10.5%)versusthe
balloonangioplastygroup(14.8%).Overall,implantationoftheTRYTONStentappears
tobecomparabletoangioplastywithregardtoheart-relatedcomplications.
ImplantationoftheTRYTONStentwasalsoassociatedwithareductionintheseverity
ofsidebranchblockageat9monthscomparedtoballoonangioplasty.
TheTRYTONExtendedAccess(EA)ConfirmatoryStudyincluded133patientswith
heartvesselbifurcationlesionsimplantedwiththeTRYTONSideBranchStenttotreat
theblockedsidebranchalongwithimplantationofanapproveddrug-elutingstentto
treattheblockageinthemajorvessel.ThefocusoftheEAStudywasontherateofheart
attacksassociatedwithimplantationoftheTRYTONStentinpatientswithheartvessel
sidebranchesthatwereoftheappropriatesizefortreatmentwiththeTRYTONStent.
TheEAstudyshowedthatdoctorscouldidentifysidebranchheartvesselsthatwere
suitedtothesizerequirementsoftheTRYTONStent inover99%oftheenrolled
patients.Therateofheartattacks(mostofwhichwereverysmall)associatedwith
implantationoftheTRYTONStentmetthegoalestablishedfortheEAstudy.
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YOURCORONARYSTENTPROCEDURE
HowDoIPrepareforMyProcedure?
Inthedayspriortoyourtreatment,makesureyou:
•
Tellyourdoctoraboutallofyourmedications
•
Takeallofyourprescribedmedicines
•
Tellyourdoctorif,foranyreason,youcannottakeaspirinorotherbloodthinning
drugssuchasPlavix,Effient,orBrilinta
•
Makesureyourdoctorknowsaboutanyallergiesyoumayhave
•
Refrainfromeatinganddrinkingaftermidnightonthenightbeforeyourprocedure
•
Followallinstructionsgiventoyoubyyourdoctorornurse
YOURTRYTONSIDEBRANCHSTENTPLACEMENTPROCEDURE
Youmaybegivenamildsedativetohelpyourelax,butyouwillnotbeputtosleep.There
aretworeasonsforthis.Firstly,mostpeoplefindtheyexperiencelittletonodiscomfort
fromtheprocedure.Secondly,yourdoctormayneedtoaskyoutotakeadeepbreathwhile
X-raysarebeingtaken,toimprovethequalityofthepictures.
Yourprocedurewillbeperformedinacardiaccatheterizationlaboratory(cathlab).You
willlieonanX-raytable,andanX-raycamerawillmoveoveryourchestduringthe
procedure.Thestaffwillmonitoryourheartbyattachingseveralsmallpatchestoyour
chestandusingaspecializedmonitor.
Thebloodvesselatthetopofyourthighisthemostcommonsiteforcatheterinsertionand
requiresaverysmallskinincision.Theareawillbeshavedandcleanedwithanantiseptic,
andyouwillbegivenalocalanesthetictonumbthearea.Thisincisionwillallowan
introducersheath(shorttube)tobeinsertedintoyourfemoralartery(themainarteryof
thethigh,supplyingbloodtotheleg).Yourdoctorwilltheninsertaguidingcatheter(along
flexibletube)intotheintroducersheathandadvanceittowherethecoronaryarteries
branchofftotheheart.Aflexibleguidewireisthenadvancedthroughtheguidingcatheter
tothenarrowinginthecoronaryartery.Thishelpscarryallthenecessarydevicesrequired
duringthestentingprocedure.
Additionaloptionsforcatheterinsertionincludeanarmartery(brachialartery)ontheinside
ofyourelbowandthewrist(radialartery).
Afterthecathetersareadvancedtoyourheart,yourdoctorwillinjectfluid(contrastdye)
throughtheguidingcatheterintoyourarterytoviewthenarrowing.Yourdoctorwillwatch
theinjectiononanX-raymonitor,muchlikeaTVscreen.WhiletheseX-raysarebeing
taken,yourdoctormayaskyoutotakeadeepbreathandholditforafewseconds.Youmay
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alsobeaskedtocoughaftertheX-raypictureiscompleted,tohelpspeedtheremovalofthe
contrastdyefromthearteries.
Usingtheguidingcatheter,aballooncatheterwillbepositionedinthenarrowinginthe
coronaryarteryandtheballoonistheninflated.Thiscompressestheplaqueandwidens
thecoronaryarteryopening.Thisprocedureiscalledpre-dilatation.Theplacementofthe
TRYTONstentisdescribedinthefollowingsteps:
Step1:Thestentmountedonaballoon
catheterisdeliveredtothenarrowinginthe
SideBranchofthecoronaryarterybya
deliverycatheter.
Theballoonistheninflatedandthisexpands
thestent,pressingitagainstthecoronary
arterywall.Yourdoctormaychoosetoexpand
thestentfurther,byusinganotherballoonso
thatthestentcanmakebettercontactwiththe
arterywall.Thisisknownaspost-dilatation.
Step2:
OncetheTRYTONSideBranchStentisinplace,
adrug-elutingstentwillbeplacedintothe
MainBranchofthearteryfollowingthesame
procedure.
Step3:Whenbothstentsareintheirpositions
yourphysicianwillexpandbothstentsfurther
byusingaballoonintheSidebranchand
anotherballoonintheMainbranch.Both
stentsremainasapermanentimplantinyour
coronaryartery.
SelectingthesizeoftheTRYTONSideBranch
Stentthatcorrectlymatchesthearterysizeis
veryimportanttoobtainthebestresultsfrom
thestentingprocedure.Yourdoctormay
choosetoperformadditionalmeasurementsof
thearterysizeusinganultrasoundcatheterbeforeorafterplacingthestents.
Theimplantationprocedureofthestentsusuallylastsabout90minutes,duringwhichtime
yourdoctorwillaskyoutoremainverystill.Forthemostpart,youwillbecomfortable,but
youmayfeelsomepressureorchestpainwheneveraballoonisinflated.Thisisnormaland
willquicklyfadewhentheballoonisdeflated.
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ImmediatelyafterProcedure
Youwillbeaskedtolieflatforfourtosixhoursfollowingtheprocedureandtonotbend
yourlegorarm,dependingonwhichareayourdoctorusedtoinsertthecatheters.
Pressurewillalsobeplacedonthearea.
Avascularclosuredevicemaybeusedtosealtheincisionsiteinyourgroinorarm.Youwill
beallowedtogetupandwalkaroundsoonerifthistypeofdeviceisused.
TakeAllMedicationsasInstructed
Afteryouleavethehospital,yourcardiologistwillinstructyoutotakeadailydoseof
aspirinandanotherbloodthinningantiplateletdrugsuchasPlavix,Effient,orBrilinta.
Yourdoctorwilltellyouhowlongyoushouldcontinuetakingtheantiplateletdrugs.Itis
veryimportantthatyoutakethesemedicationsexactlyasyourdoctorinstructsyou:
• Follow your medication schedule exactly to avoid possible complications after
youreceiveyourstent.Donotmissanydoses.
Callyourdoctorifyoucannotkeeptakingyourmedicationsbecauseofsideeffectssuchas
rash,bleeding,orupsetstomach.
CAUTION:Donotstoptakingyourprescribedmedicationsunlessyouare
instructedtodosobythedoctorwhoperformedyourstentprocedure.
CAUTION:Notifyyourdoctorifyouarescheduledtoseethedentistwhileonantiplatelet
medication.Yourdoctormayprescribeantibioticstoavoidthepotentialofaninfection.
Youshouldreviewwithyourdoctoranyrecommendationsfromyourdentistoranyother
healthcareprovidertostopyourprescribedmedications.
Ifsurgeryordentalworkthatwouldrequireyoutostoptakingantiplateletmedicationsis
recommendedafteryouhavereceivedthestent,youandyourdoctorsshouldcarefully
considertherisksandbenefitsofthissurgeryordentalworkversusthepossiblerisks
fromearlydiscontinuationofthesemedications.
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CAUTION:Beforeundergoingimplantationofadrug-elutingstent,speakwithyourdoctorif
youplantohaveanytypeofsurgerythatmayrequireyoutostoptakingantiplatelet
medications.
Ifyoudorequirediscontinuationofantiplateletmedicationsbecauseofsignificantbleeding,
yourcardiologistwillcarefullymonitoryouforpossiblecomplications.Onceyourcondition
hasstabilized,yourcardiologistmayrestartthesemedications.
Follow-upCare
Youwillbedischargedtothecareofyourcardiologistorfamilydoctor.Youshouldbe
abletoreturntoyournormalactivitiessoon.
Yourdoctorwillaskyoutoreturnforfollow-upvisits.Thefirstvisitisusuallytwotofour
weeksafteryourstentsareimplanted,withfollow-upvisitseverysixmonthsforthefirst
year.Besuretokeepallappointmentsforfollow-upcare,includingbloodtests.
CAUTION:Notifyyourdoctorimmediatelyifyouexperiencechestpain(angina),or
noticeanychangessuchasmoresevereorfrequentchestdiscomfort,especiallyinthe
firstmonthafteraprocedure.Thesesymptomsmayindicateare-narrowinginyour
coronaryarteries.
CAUTION:ShowyourPatientImplantCardifyoureporttoanemergencyroom.This
cardidentifiesyouasapatientwhohashadastentimplanted.
KeepYourPatientImplantCardHandy
MRIInformation
Ifyourequireamagneticresonanceimaging(MRI)scan,tellyourdoctororMRI
technicianthatyouhaveastentimplant.MRImaybeperformedimmediatelyfollowing
theimplantationoftheTRYTONstent(s).YourPatientImplantCardhasdetailed
informationregardingthesafestMRIconditionstobeusedafterimplantationofthe
TRYTONSideBranchStent.
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FREQUENTLYASKEDQUESTIONS
Howlongwillthestentstayinmybody?Stentsaredesignedtostayinyourbody
permanently.
WillIbeabletofeelthestentinsideme?No,youwillnotbeabletofeelthestentonceit
hasbeenimplantedinyourartery.
Canthestentmoveorrust?Oncethestentispressedagainsttheinsidewallofyour
coronaryartery,itwillremaininplacepermanentlyandwillnotmoveonitsown.Tissue
willgrowaroundthestentandholditinplace.Itwillnotrustbecauseitismadeofnoncorrodingmetal.
Willmystentsetoffthemetaldetectoratairportsecuritycheckpoints?No,yourstent
implantwillnottriggeralarmsatsecuritycheckpoints.
HowlongshouldItakemymedications?Themostimportantthingthatyoucandoto
minimizetheriskofbloodclotswithinstents(stentthrombosisis)totakethebloodthinning
antiplateletmedicationsyourdoctorprescribes.Donotstoptakingthesemedicinesuntil
yourcardiologisttellsyouto,evenifyouarefeelingbetter.
WhatifIstillgetpains?Ifyouexperiencepain,informyourcardiologistorthecenter
wheretheprocedurewasperformedimmediately.
WhataretherestrictionsorcautionsafterI’vereceivedastent?Ifyourequiremagnetic
resonanceimaging(MRI),tellyourdoctororMRItechnicianthatyouhaveanimplanted
stent.
WhencanIresumemyregularactivities?Yourdoctorwilladviseyou.Manypatientscan
returntoworkandfollowtheirnormalroutineaboutaweekaftertheirstentprocedure.
WhatshouldIchangeinmydiet?Yourdoctormayprescribeacardiacdiettohelpreduce
thelevelsoffatinyourbloodandreduceyourrisk.
CouldIhaverecurringsymptoms?Yes,itispossiblethatyouwillexperiencesymptoms
again,eitherduetoanewblockageintheregiontreatedwiththestentorduetoablockage
atanotherplaceinyourcoronaryarteries.Yourdoctorwillmonitoryourprogress.
HowcanIhelppreventarecurrenceofsymptoms?Whilethereisnosurewaytoprevent
arecurrenceofsymptoms,youcanreducetheriskthroughexercise,notsmoking,eatinga
healthydiet,andtakingrecommendedheartmedications.Yourdoctorcanadviseyouabout
lifestylechanges.
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GLOSSARY
Angina:Chestpaincausedbyaninadequatesupplyofbloodtotheheart.
Angioplasty(alsoreferredtoasPTCA):Aminimallyinvasiveprocedureinwhicha
ballooncatheterispassedthroughtotheblockedareaofanartery.Onceinflated,the
ballooncompressestheplaqueagainstthebloodvesselwallandenlargesthevessel
opening.Anangioplastycanalsobeperformedwithplacementofastent.
Anticoagulant:Amedicationtopreventorslowtheclottingofblood.
Antiplatelet:Asubstancetoreduceclumpingofplateletsintheblood.Anantiplatelet
medicinehelpsthinthebloodtopreventclotformation.
Atherosclerosis:Adiseasethatcausesnarrowingorblockageofarteriescausedbya
build-upoffat(cholesterol)withinthearterywall.Thebuild-upisreferredtoasplaque.
Bifurcationlesion:Amajorcoronaryarterywithblockagethatalsohasablockageina
sidebranch.
CardiacCatheterizationLaboratory(CathLab):AsterileX-raytheaterinwhichheart
catheterizationisperformed.
Catheter:Athin,hollow,flexibletubeusedtoaccessthecoronaryarteriesduringan
angiogramorduringanangioplastyprocedure.Thiscathetercanbeusedtoinject
medication,fluids,orcontrastdyeduringtheprocedure.Acathetercanalsorefertothe
deviceusedtodelivertheballoonorstentduringanangioplastyprocedure.
CoronaryAngiography(orHeartCatheterizationorCardiacCath):Atestinwhich
contrastdyeisinjectedtocreateimagesofthecoronaryarteries.Thisallowsthedoctorto
seetheextentofthediseaseinthecoronaryarteriesandmakeadecisiononhowtobest
treattheblockages.
CoronaryArteries:Thebloodvesselsthatcarrybloodcontainingoxygentotheheart
muscle.Therearefourmajorcoronaryarteries:theleftmain,therightcoronaryartery,the
leftanteriordescending,andtheleftcircumflex.
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CoronaryArteryBypassGraftSurgery(CABG):Open-heartsurgerytotreatCAD.
CoronaryArteryDisease(CAD):Theformationofblockagesoratheroscleroticplaques
withincoronaryarteriesthatresultinrestrictedbloodflowtotheheartmuscle.
EmboliorEmbolism:Air,piecesofdevices,orfragmentsofbloodclotsthattravelinthe
bloodstreamandblockthebloodvessel
Electrocardiogram(ECG/EKG):Atestthatrecordstheelectricalactivityoftheheart.An
ECG/EKGmayindicatethatpartsoftheheartmusclearedamagedduetodecreasedblood
flow.
FemoralArtery:Themainarteryofthethighthatsuppliesbloodtothelegandisoftenused
toinsertcatheterstoperformcoronaryangiographyprocedures.
In-stentRestenosis:Recurrentblockageornarrowingofapreviouslystentedvessel.
LocalAnesthetic:Asubstanceusedtonumbtheareatowhichitisapplied.
Lumen:Theinnerchannelorcavityofavesselortube.Inabloodvessel,itisthe
openingthroughwhichbloodflows.
MyocardialInfarction(MI):Aheartattack,whichisduetointerruptioninthebloodflow
totheheartmuscleandresultsindamageofanareaofhearttissue.
MagneticResonanceImaging(MRI):Anon-invasiveprocedureusedtoobtainimagesof
internalbodystructuresthroughtheuseofmagnetsandradiowaves.
Percutaneous:Performedthroughtheskin.
Plaque:Anaccumulationorbuild-upoffattydeposits,calcium,whitebloodcells,and
scartissueinthewallofanarterythatresultsinnarrowingofthevessellumen.
Restenosis:Arecurringblockagecausedbytheexcessivegrowthofscartissueinsidethe
arteryorstentthatmayoccurfollowinganangioplastyprocedure.
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Patient Guide, TRYTON Side Branch Stent
Stent:Ametallicmeshtubethatisimplantedintoanarteryduringanangioplasty,
providingascaffoldtohelpholdthearteryopenandincreasingbloodflowtotheheart
muscle.
TRYTONSideBranchStent/StentDeliverySystem®isregisteredtrademarksofTRYTON
MedicalInc.
PlavixisaregisteredtrademarkofSanofi-AventisCorporation.
EffientisaregisteredtrademarkofEliLillyandCompany.
BrilintaisaregisteredtrademarkoftheAstraZenecagroupofcompanies.
Formoreinformation,visitourwebsiteatwww.trytonmedical.com
Allrightsreserved.
Note:Third-partytrademarksareregisteredtrademarksoftheirrespectiveowners.
Thisproductisintendedforusebyorunderthedirectionofa
physician.Itisimportanttoreadthoroughlytheinstructions
foruse,warnings,andpotentialcomplicationsassociatedwith
theuseofthisdevice.
1000 Park 40 Plaza Suite 325
Durham, NC 27713, USA
Phone: +1.919.226.1490
Fax: +1.919.226.1497
www.trytonmedical.com
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