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The Red Eye Marc A. Booth, M.D. 10 April 2013 Objectives  Obtain a pertinent history for patients presenting with a red eye  Formulate a differential diagnosis for a patient with a red eye based on history and exam  Know when to begin therapy versus refer/defer management  Identify patients with red eye problems which require immediate referral to an ophthalmologist for treatment Pre-Lecture Quiz Question 1  Which is/are in the differential diagnosis for red eye?      A) Conjunctivitis B) Scleritis C) Ocular foreign body D) Angle Closure Glaucoma E) All of the Above Pre-Lecture Quiz Question 2  Which is not associated with acute viral conjunctivitis?      A) Mucoid or serous discharge B) Preauricular adenopathy C) Photophobia D) Palpebral (conjunctival) papillae E) Blurry vision Pre-Lecture Quiz Question 3  Which is not associated with preorbital/pre-septal cellulitis?      A) Decreased visual acuity B) Lid erythema and edema C) Ptosis D) Fever E) Full ocular motility Pre-Lecture Quiz Question 4  Which of the following has no role in treating HSV epithelial keratitis?      A) Superficial debridement B) Topical ganciclovir (Zirgan) C) Topical steroids (Pred Acetate) D) Oral Antivirals (acyclovir) E) Topical trifluridine (Viroptic) The Red Eye  Infectious  Preseptal Cellulitis  Anterior to orbital septum  globe and orbit not involved     S.aureus likely if traumatic Eyelid swollen, red, ptosis, pain, mild fever No change: vision, pupil, motility, proptosis D/Dx: Orbital cellulitis, idiopathic orbital inflammation, abscess, dacryoadenitis, dacryocystitis,  rhabdomyosarcoma (peds)  rapid, painful, progressive. 7yr old boy The Red Eye  Infectious  Preseptal Cellulitis     History: sinus surgery/disease, trauma Exam: External, Va, EOM, pupils. Ancillary tests: Orbital CT, CBC, blood cx. Treatment: Oral vs IV antibiotics  <5yr old, 48 hour po not improved --> IV, compliance, septic patient The Red Eye  Infectious  Dacryocystitis ------------->  Rhabdo  Preseptal ---------------------> The Red Eye  Infectious  Preseptal vs Orbital Cellulitis  Orbital (septal): similar to preseptal  KEY SIGNS: decreased visual acuity, afferent pupillary defect, limited ocular motility, proptosis  Most commonly secondary to ethmoidal sinusitis  Beware of Mucormycosis with DM The Red Eye  Inflammatory  Chalazion  Graves Disease The Red Eye  Inflammatory  Chalazion  Obstruction and inflammation of meibomian gland with leakage of sebum into surrounding tissue and resultant lipogranuloma formation  “Hordeolum” is secondary to an acute bacterial infection  Painful red lump on eyelid  Treat with warm compresses, incise after 4-6 weeks  If multiple, recurrent, unresponsive to treatment beware of possible sebaceous carcinoma The Red Eye  Inflammatory  Graves Disease  Variability  Asymptomatic to NLP Frozen Globe  Observation to orbital/muscle/lid surgery  Lid retraction is most common sign  Female predilection (5-8:1)  FBS, decreased vision (acuity or color), motility disturbance  Orbital CT to assess EOMs, IMSLO The Red Eye  Inflammatory  Graves Disease  Unilateral  Bilateral Skin and Adnexal Disorders  Infectious  Preseptal Cellulitis  History: sinus surgery/disease, trauma  Exam: External, Va, EOM, pupils.  Ancillary tests: Orbital CT, CBC, blood cx.  Treatment: Oral vs IV antibiotics  <5yr old, 48 hour po not improved --> IV, compliance, septic patient Post-Lecture Quiz Question 1  Which is/are in the differential diagnosis for red eye?      A) Conjunctivitis B) Scleritis C) Ocular foreign body D) Angle Closure Glaucoma E) All of the Above Post-Lecture Quiz Question 2  Which is not associated with acute viral conjunctivitis?      A) Mucoid or serous discharge B) Preauricular adenopathy C) Photophobia D) Palpebral (conjunctival) papillae E) Blurry vision Post-Lecture Quiz Question 3  Which is not associated with preorbital/pre-septal cellulitis?      A) Decreased visual acuity B) Lid erythema and edema C) Ptosis D) Fever E) Full ocular motility Post-Lecture Quiz Question 4  Which of the following has no role in treating HSV epithelial keratitis?      A) Superficial debridement B) Topical ganciclovir (Zirgan) C) Topical steroids (Pred Acetate) D) Oral Antivirals (acyclovir) E) Topical trifluridine (Viroptic)