Download PLAY FOR PINK: Play for P.I.N.K. (Prevention, Immediate diagnosis

PLAY FOR PINK: Play for P.I.N.K. (Prevention, Immediate
diagnosis, New technology, Knowledge) is a grassroots organization
dedicated to raising funds to fight breast cancer, by creating and
promoting awareness of the disease through sporting and lifestyle
events including men’s and women’s golf tournaments, tennis,
swimming, card games, equestrian events, and shopping benefits. Our
commitment is to contribute 100% of all funds raised to our sole
beneficiary, The Breast Cancer Research Foundation®.
• Due to underwriting from Bloomberg, we contribute 100% of all funds raised!
• Since 1996, PFP has donated $34 million to BCRF, $4.25 million in 2013.
• PFP holds over 300 events, in 250 clubs across 28 states.
• PFP is currently funding 16 research projects across the country and in Canada, Portugal
and Scotland.
• An estimated 30,000 men, women and children participate annually in PFP events
IF NOT FOR THE BREAST CANCER RESEARCH FOUNDATION…

WE WOULD KNOW MUCH LESS ABOUT GENETICS AND ITS RELATIONSHIP TO
BREAST CANCER.
BCRF-supported scientists have created the most comprehensive database of breast cancer genes ever
assembled. They are also studying the inherited genes that may give you a high risk of getting breast or
ovarian cancer, or that may protect you from developing either.

WE COULD STILL BE THINKING OF BREAST CANCER AS ONE DISEASE, RATHER
THAN A COLLECTION OF DISEASES.
The complexity of breast cancer is an insight uncovered by scientists, many of whose work is funded
by BCRF. The major breast cancer molecular subtypes identified to date are: luminal A, luminal B,
HER2, and triple negative (which often includes “basal-like” disease). Each disease subtype has its
own distinct patterns of progression and responds differently to existing therapies. This information
has enabled the development of personalized, or individualized, medicine, where oncologists can
“tailor-fit” a patient’s treatment according to the type of breast cancer she has.

WE WOULD HAVE FEWER DRUGS THAT HIT SPECIFIC TARGETS IN BREAST
CANCERS.
BCRF grantees have significantly improved oncologists’ ability to treat breast cancer while causing
fewer side effects. BCRF funds helped to develop and test Herceptin® (trastuzumab), a targeted
therapy for HER2+ breast cancer. This drug was reported in 2005 to decrease the risk of recurrence
for patients by 50 percent. There are many other targeted therapies currently under study by BCRF
investigators.

WE WOULD BE LESS ADVANCED IN OUR UNDERSTANDING OF BREAST
CANCER RECURRENCE AND METASTASIS.
BCRF investigators are searching for reliable and accurate markers that will help physicians identify
individuals who are at greatest risk for breast cancer recurrence and metastasis. They are developing
ways to enable doctors to stay steps ahead of the disease so that they may treat the recurrence or
metastasis as early as possible – or, ideally, even before – it takes place. They are creating clinical
interventions, using existing drugs and complementary approaches including natural supplements, to
help deter recurrence and metastasis.

WE WOULD STILL BE TREATING MANY PATIENTS WHO DO NOT NEED
THERAPY.
BCRF-funded studies in the US and Europe have contributed to the development of diagnostic tools
for doctors to evaluate whether a woman may forego chemotherapy and receive the same benefit
from hormonal therapies. Preventing overtreatment has allowed patients to avoid unnecessary side
effects.

WE WOULD KNOW MUCH LESS ABOUT HOW GOOD NUTRITION AND EXERCISE
CAN PREVENT MANY BREAST CANCERS.
BCRF investigations are substantiating the connections among diet, exercise, and health –
demonstrating that a low-fat diet and regular exercise can have a significant effect on preventing
breast cancer incidence, prognosis, and recurrence, even in women at high risk due to genetic
predisposition.

WE WOULD BE LESS ADVANCED IN OUR UNDERSTANDING OF CANCER STEM
CELLS.
BCRF-supported scientists who discovered breast cancer stem cells—the “roots” of breast cancer that
behave differently than other tumor cells—are finding out how they work and are developing
therapies designed specifically to kill them.

WE — ALL OF US, ALL OVER THE WORLD — WOULD BE FURTHER FROM OUR
GOAL OF PREVENTION AND CURE IN OUR LIFETIME.
BCRF will go anywhere in the world where there is great research. Today, BCRF funds research in
more than a dozen countries—dramatically improving diagnosis, prevention, and treatment of breast
cancer that aids women across the globe.