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International Neurourology Journal 2011;15:176-178
Atrophy of the Tongue as the Presenting
Feature of Metastatic Prostate Cancer
Zreik Abdullah, Maitrey Darrad, Sanjeev Pathak
Department of Urology, Doncaster Royal Infirmary, Doncaster, United Kingdom
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.
org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
International Neurourology Journal 2011;15:176-178
• Prostate cancer is the most frequently diagnosed solid organ cancer in men and is the
second leading cause of cancer-related deaths in men in the United Kingdom.
• Commonly, it metastasizes to bones and lymph nodes, however, in advanced
hormone-refractory disease it may involve the skull base leading to associated cranial
nerve palsies.
• Cranial nerve palsy as the presenting feature of advanced hormone-sensitive prostate
cancer is extremely rare.
• To the best of our knowledge, we report the first case of solitary hypoglossal nerve
palsy as the presenting feature of advanced prostate cancer.
• Neurologists, neurosurgeons and otolaryngologists may be the first clinicians to see
such a patient; therefore, prostate cancer should be amongst the differential
diagnoses considered in middle-aged and elderly men presenting with a cranial
neuropathy and evidence of skull metastasis.
International Neurourology Journal 2011;15:176-178
Fig. 1
International Neurourology Journal 2011;15:176-178
Fig. 2
International Neurourology Journal 2011;15:176-178
Figure Legends
Fig. 1. Patient with a right sided hypoglossal nerve palsy.
Fig. 2. Magnetic resonance imaging shows an abnormality of the right petrous bone
and hypoglossal nerve.