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1 Nutrition and the Injured Patient Diet Recommendations for Recovery Kristi Veltkamp, MS, RDN 2/28/17 2 Objectives Review healing process after injury Discuss healing and anti-inflammatory diet Identify key nutrients to promote recovery Explore ways you can help direct your patient in better nutrition 3 Goals for Nutrition in Recovery Promote healing & boost immune system Reduce inflammation Prevent weight gain Prevent muscle loss 4 Healing Phases – Acute Three Healing Phases ■ Phase 1: Inflammation – occurs immediately after surgery and continues up to 5 days post-op ■ Phase 2: Proliferation – occurs at 5 days through 3 weeks post-op. Tissue rebuilding and repairing process. ■ Phase 3: Maturation – occurs 3 weeks to 2 years post-op. Remodeling to build stronger tissue structures. 5 Phase 1: Inflammation 1. Pain. Chemicals involved in injury repair (substance P, calcitonin, histamines, cytokines) may interact with local pain receptors to cause the pain associated with inflammation as well as from swelling. 2. Swelling. This is a result of fluid seeping through damaged — and now hyper-permeable — blood vessels into the damaged tissues. 3. Redness and heat. Vasodilation up-stream of the injury and constriction downstream shunts additional blood to the injured area, producing heat and redness. 6 Phase 2: Proliferation 1. New vasculature developed with restoration of oxygen and nutrient flow for collagen/fibronectin formation (scar tissue) 2. Scar tissue formed in alignment of forces placed (PT!) 3. Maturation of scar tissue from fibroblasts to myoblasts 7 Phase 3: Maturation 1. Scar tissue degraded and type I collagen formed 2. Rehab and therapy needed to manage/arrange tissue formation 8 Chronic Wounds/Injury Chronic Inflammation/injury • Excessive inflammation, especially if it’s prolonged, can lead to other problems, such as continued macrophage activity at the site of inflammation and ongoing tissue destruction. • In this case, reduction of inflammation is key and of course, treatment of injury 9 Metabolic Changes Basal Metabolic Rate (BMR) • May increase by 15-50% based on severity of trauma • Injury or minor surgery 15-20% • Major surgery or burns 50% • Back to normal through rehab phase but may still need extra depending on intensity of rehab (crutches, exercises, ect) • Severe energy restriction will interfere with healing and recovery 10 Example Basal Metabolic Rate – 1611 kcal/day (mean of 3 predictive equations) Energy needs when sedentary – 1933 kcal/day (activity factor of 1.2) Energy needs with daily exercise activity – 2416 kcal/day (activity factor of 1.5) Energy needs during recovery – 2319 kcal/day (activity factor of 1.2 and a 20% increase in metabolism due to injury) 11 Hindrances to Good Nutrition Unable to stand/move to cook No appetite due to pain/medications Convenience foods typically nutrient poor Fear of weight gain Previous poor eating habits Lack of understanding on importance of nutrition for healing 12 Dietary Strategies Mediterranean Diet • Olive oil • Ample fruits, veggies, legumes, whole grain cereals, fish, nuts, plant proteins • Moderate red wine • Low-fat dairy • Low red meat intake 13 Mediterranean Diet • Higher n3:n6 ratio • Reduction in CVD, cancer, Parkinson's, Alzheimer's, T2DM • Reduces inflammatory markers (HS-CRP, IL-6/7/18, WBC, finbrinogen), especially in those with more olive oil and nut consumption 14 Dietary Choices – Anti-inflammatory Diet Fat (Inflammation Control) Essential for healing. Type of fat critical. Balance of Each. ■ Trans fat, omega-6 oil, saturated fats = PRO inflammation • (LESS) Fried food, margarine, baked goods, corn oil, soybean oil, vegetable oil, butter, lard, full fat dairy, high fat meats ■ Omega-3 and monounsaturated fats = ANTI inflammation • (MORE) Fish, olive oil, canola oil, nuts/seeds, avocados 15 Dietary Choices – Anti-inflammatory Diet Carbohydrate • Main energy source but needs are decreased during recovery. Concern is more about type. • White Stuff = Inflammation • (LESS) Refined grains, anything with sugar, alcohol • 16 Fiber-Rich = Healing • (MORE) Whole grains, baked potato, beans, fresh fruit, milk/yogurt, squash Glycemic Index 17 Dietary Choices – Anti-inflammatory Diet Protein • Injury repair requires more protein. Continues into rehab phase. • Normal requirements = .8g/kg • Recovery requirements = 1.5-2g/kg • Best Choices (3oz = 21 grams): • Baked/grilled chicken, fish, lean beef (limited), eggs, whey protein (if unable to get enough at meals), nuts/seeds, beans, low fat dairy 18 Dietary Choices – Anti-inflammatory Diet Vegetables and Fruits = Antioxidants • 19 Each meal/snack should contain 1-2 servings of veggies and/or fruit (1/2 – 1 1/2 cups or 1-2 pieces) with a greater focus on veggies. Anti-inflammation “Superfoods” • EVOO • Flaxseeds • Flavonoids: citrus (carotenoids), apple, cocoa, onion, celery, tea, berries, red wine • Turmeric • Fatty Fish – herring, salmon, mackerel, tuna • Magnesium-Rich Foods – Dark greens, nuts, seeds, fish, whole grains, yogurt, 20 Anti-Inflammatory/Healing Essentials Micronutrients • Vitamin A, C, D, copper, zinc, iron Additional Nutrients • Essential Amino Acids – Reduces muscle loss • Arginine – Increase wound collagen accumulation • Glutamine – Essential fuel for turning-over cells • HMB – Increase LBM • Glucosamine/chondroitin – Safe but mixed evidence •21 Omega-3s – Anti-inflammatory – supplement chronic only 22 23 Application Encourage your patients to: • Eat every 3-4 hours (include protein with each meal/snack) • Follow the Mediterranean diet • Take a multivitamin • Make homemade shakes if no appetite (whey protein, fruits, vegetables, milk/yogurt) • Include fish, nuts/seeds, avocado, olive oils daily • Eat the rainbow • Lose weight if appropriate 24 Spread the Word • You are the gateway to helping your patients understand the importance of nutrition in healing! • Needed for better success and speedy recovery. • For further help with diet and/or supplementation for healing, refer to the experts! – Physician Referral 25 Next Level Perioperative Nutrition Program • SH colorectal team started Impact nutrition supplement (nucleotides, arginine, omega-3s) pre-op • SH ortho team starting planning on perioperative program for improved outcomes from surgery • Impact 3 cartons/day 5 days pre-op and post-op • Vitamin supplementation 2-4 weeks post-op • HMB supplementation 2 weeks post-op 26 Questions? Thank you! 27 References • Understanding the Role of Nutrition and Wound Healing. Joyce K. Stechmiller, PhD, ACNP-BC, FAAN. Nutrition in Clinical Practice. Volume: 25 issue: 1, page(s): 61-68 • Nutritional Support for Exercise Induced Injuries. Tipton, K.D. Sports Med (2015) 45(Suppl 1): 93. doi:10.1007/s40279-015-0398-4. • http://oldwayspt.org/traditional-diets/mediterranean-diet • Diet and Inflammation. L. Galland, MD. Nutrition in Clinical Practice. Volume: 25 issue: 6, page(s): 634-640. • Schwingshackl L, Hoffmann G. Mediterranean dietary pattern, inflammation and endothelial function: a systematic review and meta-analysis of intervention trials. Nutr Metab Cardiovasc Dis. 2014 Sep;24(9):929-39. doi: 10.1016/j.numecd.2014.03.003. Review. PubMed PMID: 24787907. • Nutrition, Inflammation, and Disease. By Mary Franz, MS, RDN, LDN. Today’s Dietitian Vol. 16 No. 2 P. 44 • Essential amino acid supplementation in patients following total knee arthroplasty Hans C. Dreyer ... Steven N. Shah, Brian A. Jewett Hans C. Dreyer ... Steven N. Shah, Brian A. Jewett Published November 1, 2013 Citation Information: J Clin Invest. 2013;123(11):4654-4666. doi:10.1172/JCI70160. 28 References • 29 Effect of a Specialized Amino Acid Mixture on Human Collagen Deposition. Williams, Jeremy Z. MD; Abumrad, Naji MD, FACS; Barbul, Adrian MD, FACS. Annals of Surgery: September 2002 - Volume 236 - Issue 3 - pp 369-375 30