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An Introduction to Metabolism • In order to stay alive, living things must capture, store and use energy. Without energy, work cannot be done and life comes to an end. • Energy is the capacity to do work • Work is the transfer of energy from one body or place to another • Although we can see growth and movement (etc.), all work is done on a molecular level (means that everything that happens on the outside, happens because of what is going on at the molecular level). • Through chemical reactions, cells manage materials and energy to keep us alive. • Sugar possesses chemical energy. Glucose – Potential energy of life • Our bodies can break down carbohydrates (catabolic reactions) and build new material such as DNA from nucleotides (anabolic reactions). • The sum of all the anabolic and catabolic reactions occurring in a body is called metabolism. Energy • Energy exists in many forms: chemical, electrical, nuclear, heat, light, mechanical • 2 types of mechanical energy: 1) kinetic (moving objects), 2) potential (stored) Diver Example • A diver on a platform has potential energy because of gravity. • When he dives he will fall and gain speed (gaining kinetic energy) • * kinetic energy is energy possessed by moving objects • While he is falling, potential energy is converted to kinetic energy. • Energy in the universe is not created or destroyed, it can only be changed from one form to another (First law of Thermodynamics). • Most times, organisms get one type of energy and convert it to another. Plants take in light in photosynthesis, along with water and carbon dioxide and change it to glucose (chemical potential energy). • Animals eat plants to get glucose. Then, they perform cellular respiration that takes chemical energy in glucose and makes ATP. Chemical Reactions • In a chemical reaction the bonds between reactant molecules must be broken and the bonds between product molecules must form. • Energy is absorbed when reactant bonds break and energy is released when product bonds form. • The amount of energy needed to break the reactants’ bonds is called activation energy. • If activation energy is provided, reactants will reach the transition state. • The transition state is when (in a chemical reaction), the bonds within the reactants are breaking and the bonds between products are forming. Endothermic and Exothermic Reactions • Energy absorbing reactions are called endothermic reactions • Endothermic - chemical reaction in which the energy of the products is more than the energy of the reactants • Energy releasing reactions are called exothermic reactions • Exothermic - chemical reaction in which the energy of the products is less than the energy of the reactants • The universe is lazy, it prefers states that require less energy. So exothermic reactions happen often. Why do Endothermic Reactions Happen? • These types of reactions occur often in living organisms (heat, light, photosynthesis) • It would seem that exothermic reactions would happen all the time since the products require less energy than the reactants (less energy state more favorable), but this is not always the case. • Why not? • Entropy - measure of randomness or disorder in a collection of objects or energy • Entropy increases when disorder increases. • As substances become more liquid/gaseous, complex molecules form simpler molecules, things move from high concentration to low concentration, this increases entropy. • Energy and entropy both affect whether a chemical reaction will take place. • Products with the least energy requirements are favored • The universe favors an increase in entropy • See p. 61 table 2 • Readings P. 58-68 • Questions: P. 68 1,2,3,4 • Questions on handout