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Introduction to splanchnology 1. General organization of the internal organs 2. Digestive system – overview and development 3. Facial skeleton 4. Temporomandibular joint 5. Muscles of mastication 6. Teeth – types, structure and function SPLANCHNOLOGY Internal organs of human body Internal organs – viscera (splanchna): organs of the digestive, respiratory and urogenital systems located primarily in the thoracic and abdominal cavities functions – organs of vegetative state (vegetative organs) metabolism reproduction structural and functional differentiation hollow organs (tube or pouch) or parenchymal organs Prof. Dr. Nikolai Lazarov 2 SPLANCHNOLOGY Internal organs Digestive system: from cranial to caudal end of the body, mostly in the abdominal cavity Respiratory system: mainly in the thoracic cavity Urogenital system: in the lower part of the abdominal cavity and in the pelvis Prof. Dr. Nikolai Lazarov 3 SPLANCHNOLOGY Tissue structure of the internal organs Main tissues: epithelial tissue – functionally distinct tissue smooth muscle tissue connective tissue: loose connective tissue dense connective tissue reticular tissue cartilage tissue nervous tissue: nerve cells (neurons) autonomic nerves sensory receptors Prof. Dr. Nikolai Lazarov 4 SPLANCHNOLOGY General structure of hollow organs mucosa, tunica mucosa: lamina epithelialis – covering epithelium lamina propria – loose connective tissue blood and lymph vessels lymph follicles (MALT, GALT, BALT) elastic fibers, nerves and nerve structures mucosal glands – in stomach and gut lamina muscularis mucosae – smooth muscle (membrana elastica) tela submucosa blood vessels submucosal plexus (plexus of Meissner) glands – in esophagus and duodenum tunica muscularis inner circular layer myenteric plexus (plexus of Auerbach) outer longitudinal layer tunica serosa (adventitia) Prof. Dr. Nikolai Lazarov 5 SPLANCHNOLOGY General structure of parenchymal organs Parenchyma vs. Stroma Solid organs, organa solida: epithelial tissue – parenchyma connective tissue – stroma blood and lymph vessels nerve structures Structure principle: structural units lobules, segments, lobes fibrous capsule adventitia or serosa Main functions: secretion and excretion gas exchange formation of sex cells Representatives: liver, pancreas kidney, spleen ovary, glands Prof. Dr. Nikolai Lazarov 6 SPLANCHNOLOGY Methods of investigation in splanchnology dissection – macroscopic anatomy microscopic anatomy – histological structure injection-corrosion casting technique HIC MORTUI VIVOS DOCENT plastination Prof. Dr. Nikolai Lazarov 7 SPLANCHNOLOGY Methods of investigation in splanchnology Imaging anatomy: conventional radiography computed tomography (CT) magnetic resonance imaging (MRI) ultrasound technique (sonography) Prof. Dr. Nikolai Lazarov 8 SPLANCHNOLOGY Digestive system Digestion: mechanical breakdown of food chemical breakdown – enzymes traveling down of the bolus (peristalsis) absorption of the chyme elimination of waste material (defecation) Prof. Dr. Nikolai Lazarov 9 SPLANCHNOLOGY Digestive system Digestive system, systema digestorium, apparatus digestorius: alimentary canal – length 9 m mouth anus accessory digestive glands: salivary glands liver, incl. gallbladder pancreas Prof. Dr. Nikolai Lazarov 10 SPLANCHNOLOGY Alimentary canal Anterior part: mouth (oral cavity) pharynx esophagus Middle part – GI tract: stomach small intestine Posterior (terminal) part: large intestine, incl. rectum and anus Prof. Dr. Nikolai Lazarov 11 SPLANCHNOLOGY Embryonic development of the digestive system Embryogenesis: molecular regulation – homeobox genes Embryonic origin: endoderm epithelium and associated glands mesenchyme connective tissue formations smooth musculature blood and lymph vessels lymph follicles ectoderm nerve structures Prof. Dr. Nikolai Lazarov 12 SPLANCHNOLOGY Embryonic development of the digestive system Primary gut tube: foregut posterior part of oral cavity o thyroid gland pharynx o parathyroid glands o thymus esophagus stomach upper part of duodenum o liver and pancreas horizontal part of duodenum midgut small and part of large intestine proximal ⅔ of the transverse colon hindgut lateral ⅓ of the transverse colon descending, sigmoid colon and rectum Prof. Dr. Nikolai Lazarov 13 SPLANCHNOLOGY Embryonic development of the digestive system Pharyngeal arches – 4th-5th weeks of gestation: mesenchyme – paraxial and lateral mesoderm skin ectoderm endoderm Derivatives of pharyngeal arches: Prof. Dr. Nikolai Lazarov 14 SPLANCHNOLOGY Embryonic development of the digestive system Pharyngeal clefts – derivatives Pharyngeal pouches – derivatives Prof. Dr. Nikolai Lazarov 15 SPLANCHNOLOGY Bones of the head, skull, cranium Skull – 22 bones, ossa cranii: braincase, cranium cerebrale (neurocranium): twice larger paired and unpaired bones desmal, chondral and mixed ossification facial skeleton, cranium faciale (viscerocranium): mostly paired boned unpaired bones: o mandible and vomer desmal ossification Prof. Dr. Nikolai Lazarov 16 SPLANCHNOLOGY Bones of the facial skeleton, viscerocranium Paired bones: nasal bone, os nasale lacrimal bone, os lacrimale zygomatic bone, os zygomaticum maxillary bone, maxilla os incisivum (os Goethe’) palatine bone, os palatinum inferior nasal concha, concha nasalis inferior Prof. Dr. Nikolai Lazarov 17 SPLANCHNOLOGY Bones of the facial skeleton, viscerocranium Paired bones: nasal bone, os nasale lacrimal bone, os lacrimale zygomatic bone, os zygomaticum maxillary bone, maxilla os incisivum (os Goethe’) palatine bone, os palatinum inferior nasal concha, concha nasalis inferior Prof. Dr. Nikolai Lazarov 18 SPLANCHNOLOGY Bones of the facial skeleton, viscerocranium Unpaired bones: mandible, mandibula vomer, vomer hyoid bone, os hyoideum Prof. Dr. Nikolai Lazarov 19 SPLANCHNOLOGY Temporomandibular joint, articulatio temporomandibularis Joint structure: articular surfaces articular disk fibrous capsule synovial membrane ligaments Prof. Dr. Nikolai Lazarov 20 SPLANCHNOLOGY Kinesiology of the joint Biomechanics of the temporomandibular joint: Prof. Dr. Nikolai Lazarov 21 SPLANCHNOLOGY Muscles of the head, musculi capitis Masticatory muscles Mimic (facial) muscles – groups: scalp and auricular groups orbital group oral and nasal groups Deep occipital muscles Muscles of the: eye middle ear tongue soft palate and pharynx Suprahyoid muscles Prof. Dr. Nikolai Lazarov 22 SPLANCHNOLOGY Muscles of mastication, mm. masticatorii Masticatory muscles: origin from different parts of the skull attached to the mandible derived from the first branchial (pharyngeal) arch nerve supply by the homonymous branches of the mandibular nerve (trigeminal nerve) concerned with the movements of the mandible in mastication jaw-closing muscles primary and accessory muscles of mastication Prof. Dr. Nikolai Lazarov 23 SPLANCHNOLOGY Muscles of mastication, mm. masticatorii Masseter muscle, m. masseter Temporal muscle, m. temporalis Medial pterygoid muscle, m. pterygoideus medialis Lateral pterygoid muscle, m. pterygoideus lateralis Prof. Dr. Nikolai Lazarov 24 SPLANCHNOLOGY Masseter muscle, m. masseter thick, somewhat quadrilateral muscle at the side of the face superficial portion: origin from zygomatic bone anterior end of the zygomatic arch insertion to the tuberositas masseterica mandibulae deep portion – much smaller: origin from the inner part of the zygomatic arch temporal fascia insertion to the outer part of the mandibular ramus elevation and retraction of the lower jaw (mandible) innervation: n. massetericus (mandibular division, V3 of the trigeminal nerve) Prof. Dr. Nikolai Lazarov 25 SPLANCHNOLOGY Temporal muscle, m. temporalis arises from the temporal fossa covered by the lamina profunda of the temporal fascia (aponeurosis) fan-shaped with origin from: linea temporalis inferior squama temporalis ala major ossis sphenoidalis and os zygomaticum fascia temporalis insertion onto the coronoid process of the mandible (proc. coronoideus mandibulae) the anterior vertical fibers retrude and elevate the mandible mouth closure the posterior horizontal fibers retract the mandible innervation by the deep temporal nerves (nn. temporales profundi) Prof. Dr. Nikolai Lazarov 26 SPLANCHNOLOGY Medial pterygoid muscle, m. pterygoideus medialis thick, quadrilateral muscle of mastication located in the infratemporal fossa, medially from the mandibular ramus, vertically directed superficial head, caput mediale – smaller, origin from the: pyramidal process of the palatine bone tuberosity of the maxilla deep head, caput laterale – origin from the: medial surface of the lateral pterygoid plate fossa separating this and the medial plate insertion into the medial surface of the angle of the mandible posterior to the mylohyoid groove elevation of the mandible closes the jaw contribution to protrusion of the mandible excursion of the mandible innervation: the nerve to medial pterygoid (n. pterygoideus medialis) Prof. Dr. Nikolai Lazarov 27 SPLANCHNOLOGY Lateral pterygoid muscle, m. pterygoideus lateralis a short, thick muscle, somewhat conical in form extends almost horizontally opening the jaw superior part, pars superior arises from: the infratemporal surface and infratemporal crest of the greater wing of the sphenoid bone inferior part, pars inferior: originates on the lateral surface of the lateral pterygoid plate insertion onto: fovea pterygoidea mandibulae articular disk and fibrous capsule of the temporomandibular joint (upper head) the neck of condyle of the mandible (lower head) helping lower the mandible and open the jaw unilateral action produces contralateral excursion innervation: n. pterygoideus lateralis Prof. Dr. Nikolai Lazarov 28 SPLANCHNOLOGY Teeth, dentes Teeth, dentes (Gr. odus, odontos): mechanical breakdown (chew) of food help in phonation derivatives of oral mucosa Permanent teeth, dentes permanentes: 32 teeth into two symmetrical halves Deciduous (milk) teeth, dentes decidui: the first set of teeth in the growth development of humans 20 teeth into two symmetrical halves Prof. Dr. Nikolai Lazarov 29 Thank you…