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Ingestion Digestion Absorption elimination Ingestion (human) • In the mouth – food is broken down physically by the teeth and chemically by saliva • Saliva is a mixture of water and amylase, an enzyme that breaks down starch. Saliva lubricates the food so it can be swallowed and makes it possible to taste the food we eat • Teeth – incisors for cutting, canines for tearing, premolars for grinding, molars for crushing • In the esophagus – after leaving the mouth, food descends the esophagus – the tube between the mouth and the stomach • The food stretches the walls of the esophagus, activating peristalsis – a series of muscular contractions and relaxations that resemble waves, that move food along to the stomach (even if you do a headstand!!) Questions about ingestion 1. What are the functions of saliva? 2. How does chewing help in the digestion of food? 3. What are amylase enzymes and why are they necessary? Digestion (human) • Stomach - Site of food storage and the digestion of proteins • The stomach is in the shape of a “J” and can hold 1.5L of food • The cells lining the interior of the stomach secrete fluids that help with digestion (gastric juices). The stomach secretes 500 mL of gastric juices after every meal. • Gastric juices – fluids that help with digestion, including: – Mucosal lining - provides a protective coating for the cells of the stomach – HCl (hydrochloric acid) - kills harmful substances ingested with food – Pepsinogen - becomes pepsin, a digestive enzyme • The pH of the stomach is between 1.5 and 3.0 • The mucosal lining is basic and protects the cells lining the interior of the stomach from being broken down. • Small intestine – Where the majority of digestion takes place. • In humans, it is 7m long and 2.5cm wide (the large intestine is 1.5m long and 7.6cm wide) • The majority of digestion happens in the first 25-30cm of the small intestine, which is called the duodenum • Pancreas – a digestive organ that secretes a bicarbonate ion solution into the small intestine that neutralizes the HCl and denatures pepsin so the cells lining the intestine are not damaged by the gastric juices • The pancreas also secretes enzymes which break down food – proteins trypsin and erepsin – carbohydrates: amylase and disaccharidases – lipids: lipase • Liver – digestive organ that produces bile, which is used to break down lipids • Bile is stored and concentrated in the gall bladder • Bile is released into the small intestine to physically break down lipids so they can be chemically digested by enzymes (lipases) Questions on digestion 1. How are the cells of the small intestine protected from stomach acids? Explain the mechanism and the chemicals involved. 2. In cases of extreme obesity, a section of the small intestine can be removed. What effect do you think this would have on the patient? Absorption and elimination (human) • The majority of absorption happens in the small intestine. The intestinal walls are covered with villi, projections that increase the surface area of the walls to maximise absorption of nutrients. Villi are themselves covered with microvilli to create even greater surface area • When they are absorbed across the intestinal walls, nutrients enter the circulatory system and are delivered throughout the body • The colon – (large intestine) stores waste for the time it takes the body to absorb water, salts and vitamins • Cellulose (fiber) cannot be broken down by our bodies but it provides volume to our solid waste. Once the volume of waste reaches a certain quantity, a signal is sent to the nervous system, which initialises defecation. • Elimination removes toxic waste from our bodies. The more cellulose we eat, the more defecations we will have and the less time the toxins remain in our bodies Questions on absorption and elimination 1. What is the function of the colon in the digestive system? 2. Why is cellulose considered to be an important part of your diet? 3. Describe what the inside of the small intestine looks like and how this structure increases the efficiency of its operation.