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(STI’s & STD’s) 8th grade Illnesses transmitted by vaginal intercourse, oral sex, and anal sex. Some STIs can be transmitted via IV drug needles, childbirth or breastfeeding. Sexually transmitted infections have been well known for hundreds of years. http://en.wikipedia.org/wiki/Sexually_transmitted_disease “Disease" implies the presence of symptoms that the infected person is aware of. “Infection” has a broader range of meaning ◦ a person may be infected, and may potentially infect others, without having a disease. The most recent national estimates: ◦ approximately 19 million new cases of STIs each year ◦ half of them among 15–24-year-olds ◦ 65 million Americans have at least one viral STI, most commonly genital herpes. http://www.guttmacher.org/pubs/FIB_STI_US.html http://www.labsdirect.com/ Parasite ◦ Pubic Lice (crabs), Bacterial ◦ Chlamydia, ◦ Gonorrhea, ◦ Syphilis Viral ◦ ◦ ◦ ◦ Hepatitis B, Herpes (simplex 1 and 2), HIV, HPV Parasite Also known as “crabs” Infest human pubic hair They feed exclusively on blood Main symptom is itching, usually in the pubic-hair area. Sexual contact, especially genital region, with infected person. Shared towels, sheets, clothing, etc. Crab lice can be treated with cream rinse. ◦ These agents should be applied to the affected areas and washed off after 10 minutes. Shaving off or grooming infected hair. Prescribed shampoo that is approved by the U.S. Food and Drug Administration (FDA) Worldwide, it is estimated that 2 % of human population have it. ◦ Accurate numbers are difficult to acquire. http://en.wikipedia.org/wiki/Pubic_lice A bacteria Known as a "silent" disease because it is often symptomless. If symptoms do occur, they usually appear within 1 to 3 weeks after exposure. Women: ◦ Pain in vaginal area. ◦ abnormal vaginal discharge ◦ burning sensation when urinating. ◦ lower abdominal pain, ◦ low back pain, nausea, fever, pain during intercourse, ◦ bleeding between menstrual periods. Men: discharge from their penis burning sensation when urinating. burning and itching around the opening of the penis. Pain and swelling in the testicles are uncommon. Serious reproductive problems. Infection can spread into the uterus or fallopian tubes and cause pelvic inflammatory disease (PID). ◦ Permanent damage to the fallopian tubes, uterus, and surrounding tissues that can lead to chronic pelvic pain, infertility, and potentially fatal ectopic pregnancy (pregnancy outside the uterus). Babies who are born to infected mothers can get chlamydial infections in their eyes and respiratory tracts. Chlamydia is a leading cause of early infant pneumonia and conjunctivitis (pink eye) in newborns. Vaginal, anal, or oral sex. Chlamydia can also be passed from an infected mother to her baby during vaginal childbirth. Easily treated with antibiotics. ◦ A single dose of azithromycin ◦ All sex partners should be evaluated, tested, and treated. Chlamydia is the most frequently reported bacterial sexually transmitted disease in the United States. In 2009, 1,244,180 chlamydial infections were reported to CDC from 50 states and the District of Columbia. An estimated 2.8 million infections occur annually in the U.S. Women are frequently re-infected if their sex partners are not treated. http://www.cdc.gov/std/chlamydia/default.htm A bacteria This bacteria can grow and multiply easily in the warm, moist areas of the reproductive tract The bacterium can also grow in the mouth, throat, eyes, and anus. Women: Most women have no symptoms. Symptoms are often mistaken for a bladder or vaginal infection. Painful or burning sensation when urinating, increased vaginal discharge, or vaginal bleeding between periods. Men: Some have no symptoms Burning sensation when urinating, or a white, yellow, or green discharge from the penis. Painful or swollen testicles. Women: Pelvic Inflammatory Disease (PID). About 750,000 women each year in the United States develop PID. Men: Epididymitis, a painful condition of the ducts attached to the testicles that may lead to infertility if left untreated. Contact with the penis, vagina, mouth, or anus. Ejaculation does not have to occur for gonorrhea to be transmitted or acquired. From mother to baby during delivery. Antibiotics can successfully cure gonorrhea in adolescents and adults. Drug-resistant strains of gonorrhea are increasing in many areas of the world, including the United States, and successful treatment of gonorrhea is becoming more difficult. CDC now recommends dual therapy (i.e. using two drugs) for the treatment of gonorrhea. Persons with gonorrhea should be tested for other STDs. Gonorrhea is a very common infectious disease. CDC estimates that more than 700,000 persons in the U.S. get new gonorrheal infections each year. Less than half of these infections are reported to CDC. In 2009, 301,174 cases of gonorrhea were reported to CDC. http://www.cdc.gov/std/gonorrhea/STDFact-gonorrhea.htm A bacteria It has often been called "the great imitator" because so many of the signs and symptoms are indistinguishable from those of other diseases. Many people have NO symptoms for years, yet remain at risk for late complications if they are not treated. There are 3 potential stages of syphilis: ◦ Primary ◦ Secondary ◦ Latent Direct contact with a syphilis sore. Sores occur mainly on the external genitals, vagina, anus, or in the rectum. Occurs during vaginal, anal, or oral sex. Pregnant women with the disease can pass it to the babies they are carrying. Syphilis cannot be spread through contact with toilet seats, doorknobs, swimming pools, hot tubs, bathtubs, shared clothing, or eating utensils. Marked by the appearance of a single sore (called a canker). The canker is usually firm, round, small, and painless. The canker lasts 3 to 6 weeks, and it can heal without treatment. However, if adequate treatment is not administered, the infection progresses to the secondary stage. Skin rash and mucous membrane lesions. Rough, red, or reddish brown spots both on the palms of the hands and the bottoms of the feet. Without treatment, the infection will progress to the latent and possibly late stages of disease. Called the hidden stage Damages the internal organs, including the brain, nerves, eyes, heart, blood vessels, liver, bones, and joints. Signs and symptoms include difficulty coordinating muscle movements, paralysis, numbness, gradual blindness, and dementia. This damage may be serious enough to cause death. It is rare for syphilis to reach this stage this day in age. Easy to cure in its early stages. A single intramuscular injection of penicillin, an antibiotic, will cure a person who has had syphilis for less than a year. Treatment will kill the syphilis bacterium and prevent further damage, but it will not repair damage already done. In the United States, health officials reported over 36,000 cases of syphilis in 2006. Syphilis dates back to the 1400’s. Many famous historical figures, including Henry VIII, Adolf Hitler, Benito Mussolini, Al Capone, Vincent Van Gogh and Ivan the Terrible, are alleged to have had syphilis or other sexually transmitted infections. http://en.wikipedia.org/wiki/History_of_syphilis http://www.cdc.gov/std/syphilis/STDFact-Syphilis.htm Virus A serious liver infection caused by the hepatitis B virus (HBV) The highest concentrations of HBV are found in blood. ◦ Lower concentrations found in other body fluids including semen, vaginal secretions, and saliva. Appear about 2-3 months after you've been infected and can range from mild to severe. Signs and symptoms of hepatitis B may include: ◦ ◦ ◦ ◦ ◦ ◦ ◦ Abdominal pain Dark urine Joint pain Loss of appetite Nausea and vomiting Weakness and fatigue Yellowing of your skin and the whites of your eyes (jaundice) Through blood, semen or other body fluids. Common ways HBV is transmitted include: ◦ Sexual contact – unprotected sex ◦ Sharing needles – drug use ◦ Accidental needle sticks- health care workers ◦ From mother to child - during childbirth Acute hepatitis B infection ◦ lasts less than six months. ◦ your immune system is usually able to clear the virus ◦ you should recover completely within a few months Chronic hepatitis B infection lasts six months or longer. your immune system can't fight off the virus infection may become lifelong, May lead to serious illnesses such as cirrhosis and liver cancer. Receiving an injection of hepatitis B immune globulin within 24 hours of coming in contact with the virus may help protect you from developing hepatitis B. Acute HBV may not need treatment. Chronic HBV will need antiviral medication and the possibility of a liver transplant (only if the liver is severely damaged). http://www.bing.com/health/article/mayo-MADS00398/Hepatitis-B?q=hepatitis+b 2 billion people worldwide 12 million in the United States http://www.hepb.org/hepb/statistics.htm Virus Caused by the herpes simplex viruses type 1 (HSV-1) or type 2 (HSV-2). Most genital herpes is caused by HSV-2. No or only minimal signs or symptoms from HSV-1 or HSV-2 infection. Painful sores or cankers on or around the mouth, genitals or rectum, flu-like symptoms, including fever and swollen glands. Blisters may take two to four weeks to heal the first time they occur. HSV-1 can cause genital herpes, but it more commonly causes cold sores. HSV-1 infection of the genitals can be caused by oral-genital or genital-genital contact with a person who has HSV-1 infection. HSV-2 during sexual contact with someone who has HSV-2. Transmission can occur from an infected partner who does not have a visible sore and may not know that he or she is infected. Oral herpes is what causes cold sores (common) Cold Sores appear on the external areas around the mouth such as the lips, chin, cheeks and around the throat area. The virus that causes oral herpes is highly contagious and is referred to as the "kissing disease". Canker Sores are located on the inside of the mouth (from stress, genetics, food allergy, fatigue, etc.) Genital herpes frequently causes psychological distress in people who know they are infected. Potentially fatal infections in babies. Herpes may play a role in the spread of HIV, the virus that causes AIDS. WHY??? There is no treatment that can cure herpes, but antiviral medications can shorten and prevent outbreaks during the period of time the person takes the medication. Results of a nationally representative study show that genital herpes infection is common in the United States. Nationwide, about one out of six, people 14 to 49 years of age have genital HSV-2 infection. Genital HSV-2 infection is more common in women. http://www.cdc.gov/std/Herpes/STDFact-Herpes.htm Human Immunodeficiency Virus HIV cannot grow or reproduce on their own, they need to infect the cells of a living organism in order to replicate The human immune system usually finds and kills viruses fairly quickly HIV attacks the immune system making it difficult or impossible to kill the virus. A part of white blood cells that fight infection. HIV attacks T-Cells (the main target for HIV) NUMBERS: ◦ healthy adult = 600 to 1200 ◦ HIV+ person = 600 and 350 considered "very good“ ◦ 350 and 200 = The immune system is weakened and therefore the HIV+ person may be at increased risk for infection and illness. ◦ Less that 200 = The immune system is severely weakened and the HIV+ person is at a much greater risk of opportunistic infections. http://wiki.answers.com/Q/How_many_T-cells_should_you_have#ixzz1jBW5G3xu Acquired Immune Deficiency Syndrome AIDS is caused by HIV damaging the immune system cells until the immune system can no longer fight off other infections that it would usually be able to prevent. Often no symptoms at all. It's NOT possible to tell just by looking if someone has been infected with HIV. Some people experience a flu-like illness, develop a rash, or get swollen glands. However, these are also common symptoms of other less serious illnesses, and do not necessarily mean that a person has HIV. The only way to know for certain if someone is infected with HIV is for them to be tested. 6 bodily fluids: Unprotected sexual intercourse with an infected person Contact with an infected person's blood Use of infected blood products: blood transfusions Injecting drugs From mother to child: http://www.avert.org/hiv.htm Blood Semen Pre-ejaculatory fluid Breast milk Vaginal fluid Rectal fluid antiretroviral drug treatment ◦ It is not a cure ◦ Helps keep the immune system strong. combination therapy ◦ Taking two or more antiretroviral drugs at a time is called combination therapy. ◦ Taking two or more antiretroviral at the same time vastly reduces the rate at which resistance would develop, making treatment more effective in the long term. http://www.avert.org/treatment.htm People living with HIV: ◦ Worldwide - 33.3 million (2009) ◦ US - 682,668 (2008) ◦ Africa – An estimated 22.5 million people were living with HIV in sub-Saharan Africa at the end of 2009, including 2.3 million children. ◦ During 2009, an estimated 1.3 million Africans died from AIDS. http://www.avert.org/africa-hiv-aids-statistics.htm First recognizable case in the US was in 1981 (Ryan White – 13, contaminated blood transfusion) . He had hemophilia (blood doesn’t clot properly) Died 5 1/5 years later 5 theories: ◦ ◦ ◦ ◦ ◦ ‘Hunters’ theory Oral polio vaccine (OPV) theory Contaminated needle theory Colonialism theory Conspiracy theory http://www.avert.org/origin-aids-hiv.htm Magic! Human Papilloma Virus The most common sexually transmitted infection (STI). There are more than 40 HPV types that can infect the genital areas of males and females. These HPV types can also infect the mouth and throat. http://www.cdc.gov/STD/HPV/STDFact-HPV.htm Most people with HPV do not develop symptoms or health problems from it. In 90% of cases, the body’s immune system clears HPV naturally within two years. Genital warts Warts in the throat (rare) Cervical cancer (when left untreated) HPV is passed on through genital contact, most often during vaginal and anal sex. It may also be passed on during oral sex It can be passed on between straight and same-sex partners—even when the infected partner has no signs or symptoms. Females: Two vaccines (Cervarix and Gardasil) are available to protect females against the types of HPV that cause most cervical cancers. ◦ Recommended for girls age 11 - 26 years of age, who did not get any or all of the shots when they were younger. It is recommended to get the same vaccine brand for all three doses, whenever possible. Males: One available vaccine (Gardasil) protects males against most genital warts and anal cancers. ◦ This vaccine is available for boys and men, 9 through 26 years of age. There is NO treatment for the virus itself, but there are treatments for the diseases that HPV can cause: ◦ Genital warts can be removed by the patient him or herself with prescribed medications. ◦ Cervical cancer is most treatable when it is diagnosed and treated early. But women who get routine Pap tests and follow up as needed can identify problems before cancer develops. Approximately 20 million Americans are currently infected with HPV. Another 6 million people become newly infected each year. HPV is so common that at least 50% of sexually active men and women get it at some point in their lives.