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Transcript
Economic Indicators of
Clinical Research
in British Columbia
Dr. W. Robert McMaster
Access to Innovation:
R&D Investment in Life Sciences in B.C
October 14, 2015
Clinical Research in British Columbia
• Research and innovation are fundamental building
blocks for economic growth and success
• Clinical research is an important component of BC
economy
• A robust clinical research environment is key to
achieving the economic and patient care benefits in BC
The Value of Clinical Research
• For the economy
◦ For every million dollars of expenditure on clinical research,
the estimated increase in GDP is $947,000
• For the health care system
◦ Attract and retain the best clinicians, resulting in improved
treatments and better health outcomes
• For the industry
◦ Enable the early stage development and commercialization
efforts of pharmaceutical and biotechnology companies
• For patients and families
◦ Provide access to cutting edge research and heath care
professionals
VCH Research Institute (VCHRI)
• Major player in BC’s Health Research Industry
• Focus on discovery and research that directly impacts
health and economic outcomes
 New treatments for British Columbians
 Impact on supply and demand of health services
 Diversification of the economic gains through new jobs and
technology transfer
 Commercialization and biotechnology company spinoffs
BC Clinical Research Infrastructure Network
(BCCRIN)
• A collaborative partnership of health authorities,
research institutes, universities, industry and funding
agencies
• Pursue an optimized provincial environment for clinical
research that results in the best patient care decisions
and strategies for a sustainable health care system
 Promote BC as a premier location for clinical trials to increase
investment
 implement strategies for clinical research engagement
 Provide standardization of clinical research quality,
methodological and technology support
Research Funding at Academic Health Sites
2014-2015 Total Funding $264 M
BC Mental Health and
Addiction Services
Research Institute
1%
Women's Health Research
Institute
1%
Vancouver Coastal Health
Research Institute
33%
BC Centre for Disease
Control
1%
Providence Health Care
Research institute
17%
Child & Family Research
Institute
19%
BC Cancer Agency
28%
Size and Scope of Research Funding at VCRHI
• VCHRI is one of the top funded research institutes in
Canada: $85.9M in research funding for 2014–2015
Contracts
2%
$2.4M
Clinical Trials
16%
$13.4M
Agreements
14%
$11.8M
Grants & Awards
68%
$58.2M
Sources of Research Funding at VCHRI
Industry
13%
$11.4M
Non-profit
41%
$35.1M
Government
(Tri-Council)
34%
$24.2M
Government
(Other Agencies)
29%
$15.2M
BC Clinical Research Infrastructure Network
(BCCRIN)
• BCCRIN Economic Report by MMK Consulting in 2013
◦ Assess the economic importance of clinical research – direct,
indirect (suppliers), and inducted (workforce re-spending)
impacts of clinical economic activity being undertaken in BC
Economic Indicators of Clinical Research in BC
Employment
4,000 Jobs
10%
31%
Gross Domestic Product
$240 M
Government Revenues
$25.5 M
13%
59%
9%
57%
30%
33%
58%
Direct
Direct
Federal
Indirect
Indirect
Provincial
Induced
Induced
Local
Clinical Research Economic Impacts
[relative to other industry sectors]
• Clinical research generates modestly higher total GDP
per unit of direct output, and is a strong employment
generator
24
$947
$940
22
21.78
$940
$860
20
Employment
$900
$800
18
16
$1,000
16.64
15.76
$700
14
$600
12
$500
10
$400
8
$300
6
$200
3.73
4
$100
2
0
BC clinical
research
Mining and
Oil & gas
Prof., Scientific &
Tech. Serv.
Note: Selected industry multipliers taken from BC Stats Economic Multipliers Report
Retail Trade
$0
GDP
('000)
Innovative health research
• Innovation (an idea, device, or process)
= key to transform the future of health care
• An important component in advancing innovation
= the transition from discovery to practice
• Problem
◦ the adoption and implementation of early-stage technologies
and treatment options within the health system
• Solution
◦ Pacific Health Innovation eXchange (PHIX)
Pacific Health Innovation eXchange (PHIX)
Research-to-Clinical Care Valleys
• A dual challenge in integrating research into practice
Valley 1
decreased capacity to
translate research
discoveries to bedside
Research
Valley 2
limited capacity to synthesize,
disseminate and integrate research
into health care decision-making
and clinical practice
Education
Challenges to integrate
Clinical Care
Pacific Health Innovation eXchange (PHIX)
• Pacific Health Innovation eXchange (PHIX)
◦ Vision “The PHIX will be a global powerhouse focused on
bringing novel approaches to the delivery of person-centered
care and sustainability to the health care system. It will foster
world-wide collaboration and facilitate discovery to adoption,
contributing to the economic and social fabric of our city,
province, country, and world.”
• PHIX will ‘serve as a conduit and catalyst’ for providers,
researchers, entrepreneurs, the public and health system
leaders in a AHSN to share ideas and facilitate adoption of
innovation into the health system


social benefits (improved access to care, health outcomes)
economic impacts (new investments, jobs and companies)
Facilitate discovery to adoption
• PHIX will ‘connect the dots’ for providers,
researchers, entrepreneurs, the public and health
system leaders in BC to share ideas and facilitate
adoption of innovation into the health system
• Focus on facilitating
innovations that share
common outcomes and
provide efficiency gains within
the health system
Creating an Ecosystem
• PHIX is envisioned as an ecosystem of collaboration
to connect the efforts of researchers, entrepreneurs,
clinicians and health system leaders
- Heritage Heather Restoration
- Heather Expansion
- MediTech
Alignment of Expertise and Resources
• AHSN will build on existing strengths in BC to build a
truly provincial network (supported by SPOR) that
integrates health services, teaching, research and
commercialization
Economic Impact through the creation of PHIX
• Research economic benefits
 The value of annual research grants invested
 Increased number of clinical trials conducted at PHIX
• Commercialization and adoption benefits
 Creating new jobs – up to 3,700 jobs
 Growing the economy - adding $218-$274M to GDP
 Creating new companies - attracting investment and nurturing
partnerships
Thank You