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Postdoctoral position in Immunology, Albert Einstein College of Medicine, NY, USA: An opportunity exists for a highly motivated fellow in the laboratory of Grégoire Lauvau. The main focus of the lab is to understand basic mechanisms of immunity against microbial pathogens. We are focusing on the molecular and the cellular signals involved in inducing, maintaining and mediating protective innate and adaptive effector and memory response against intracellular pathogens in vivo. We use distinct surrogate mice models of infection and vaccination, in particular the intracellular bacterium Listeria monocytogenes (Lm) and blood stage malaria with the parasites Plasmodium yoelii and chabaudi. The current postdoctoral research project is building on findings and reagents of the laboratory using in vivo immunology approaches and will focus on the functions of memory T cells and their interactions with innate immune effector cells (Soudja et al., Immunity 2014 and 2012, NarniMancinelli et al., PLoS Pathogens 2011). The project will involve all usual techniques of Immunology and a combination of molecular and cellular biology, biochemistry and microbiology. We have also developed novel fluorescent tracer-expressing mice and Cre/Lox systems to investigate specific questions related to our previous findings. The successful candidate should have a strong theoretical background and experience in molecular and cellular Immunology (FACS, Immune functional assays, Mouse work), and excellent skills in tissue imaging (confocal and/or intravital microscopy). Presentation at meetings will be encouraged. Individuals who are interested should hold a PhD and/or an MD degree and send a CV with a brief statement of research interests and the name and email of two references to: Grégoire Lauvau, Ph. D. Biology of Antimicrobial Immune Effector Cell Differentiation Jack and Pearl Resnick Campus, Price building, Bronx, NY 10461 Email: [email protected] http://www.einstein.yu.edu/faculty/11605/gregoire-lauvau/ The Albert Einstein College of Medicine is one of the USA premier institutions for medical education, basic research and clinical investigation. While education is at the heart of the College’s mission, it is biomedical research that drives the College’s growth. Einstein’s 300 research laboratories are its crucibles of creativity. Long a national leader in biomedical research support from the Federal government, in 2013, Einstein faculty received more than $150 million in funding from the National Institutes of Health. https://www.einstein.yu.edu/about/ The Department of Microbiology and Immunology at the Albert Einstein College of Medicine is a big tent dedicated to excellence in research with the ultimate goals of improving human health and training the next generation of biomedical research scientists. The faculty comprises a unique combination of basic researchers, and physician-scientists who have additional appointments in clinical divisions such as Infectious Diseases, Rheumatology, and Allergy and Immunology. Faculty interests include the genetics and molecular biology of prokaryotic and eukaryotic microorganisms, the cellular and immunological mechanisms involved in pathogenesis and host defense, and the interactions of a wide variety of microbes with their hosts. Department laboratories are located in the Forchheimer, Chanin, Golding, and Ullmann Buildings, and in the new Michael F. Price Center for Genetic and Translational Medicine http://www.einstein.yu.edu/departments/microbiology-immunology/