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Rituxan® (Rituximab) Medication Precertification Request Aetna Precertification Notification 503 Sunport Lane, Orlando, FL 32809 Phone: 1-866-503-0857 FAX: 1-888-267-3277 Page 1 of 2 (All fields must be completed and return both pages for precertification review) Please indicate: Start of treatment, start date: / / Continuation of therapy, date of last treatment: Precertification Requested By: A. PATIENT INFORMATION First Name: Address: Home Phone: DOB: Allergies: Current Weight: lbs or B. INSURANCE INFORMATION For Medicare Advantage Part B: FAX: 1-844-268-7263 Phone: Last Name: City: Work Phone: / / Fax: State: ZIP: Cell Phone: E-mail: kgs Height: inches or cms Does patient have other coverage? Yes No Aetna Member ID #: If yes, provide ID#: Carrier Name: Group #: Insured: Insured: Medicare: Yes No If yes, provide ID #: Medicaid: Yes No If yes, provide ID #: C. PRESCRIBER INFORMATION First Name: Last Name: (Check one): M.D. D.O. N.P. Address: City: State: ZIP: Phone: Fax: St Lic #: NPI #: DEA #: UPIN: Provider E-mail: Office Contact Name: Phone: Specialty (Check one): Rheumatologist Other: D. DISPENSING PROVIDER/ADMINISTRATION INFORMATION Place of Administration: Dispensing Provider/Pharmacy: Patient Selected choice Physician’s Office Retail Pharmacy Self-administered Physician’s Office Outpatient Infusion Center Phone: Specialty Pharmacy Mail Order Center Name: Other: Home Infusion Center Phone: Name: Agency Name: Phone: Fax: Administration code(s) (CPT): TIN: PIN: P.A. E. PRODUCT INFORMATION Rituxan: Dose: Directions for Use: F. DIAGNOSIS INFORMATION - Please indicate primary ICD code and specify any other any other where applicable (*). Primary ICD Code: Other ICD Code: G. CLINICAL INFORMATION - Required clinical information must be completed for ALL precertification requests. Yes No Will Rituxan be used in combination with other biologic agents (e.g., Arzerra, Cimzia, Cosentyx, Enbrel, Humira, Kineret, Remicade, etc.)? Please check ALL that apply: Acute lymphoid leukemia (induction/consolidation therapy for Philadelphia chromosome negative) Refractory autoimmune hemolytic anemia Anti-neutrophil cytoplasmic antibody-associated (ANCA-associated) vasculitides (Wegener granulomatosis, Churg-Strauss syndrome, microscopic polyangiitis, and pauci-immune glomerulonephritis) Yes No Has the patient had an inadequate response to cyclophosphamide? Yes No Will Rituxan be given in conjunction with glucocorticoids? Antibody mediated rejection in heart transplant recipients (prevention of recurrence) Chronic lymphocytic leukemia Chronic graft versus host disease (last resort treatment) Corticosteroid-refractory autoimmune blistering diseases (pemphigus vulgaris, pemphigus folliaceus, bullous pemphigoid, cicatricial pemphigoid, epidermolysis bullosa acquisita and paraneoplastic pemphigus) Cryoglobulinemia refractory to corticosteroids and other immunosuppressive agents Refractory immune or idiopathic thrombocytopenic purpura Refractory thrombotic thrombocytopenic purpura Lymphocyte-predominant Hodgkins lymphoma Multi-centric Castleman's disease (angiofollicular lymph node hyperplasia) Neuromyelitis optica Yes No Has the patient failed one or more immunotherapies? If yes, please provide the name(s) and date range used: Name(s):____________________________________________ Date ranges: / / / Non-Hodgkin's lymphoma Yes No Has the patient received Rituxan infusions in the past? If yes, please provide the name(s) and date range used: / Name(s):____________________________________________ Date range: / / / / Yes No Has the patient received more than 2 courses of infusions (each course may entail 4 to 8 weekly infusions) in 48 weeks? Post-transplant lymphoproliferative disorder Prophylaxis of rejection in sensitized kidney transplant recipients with donor specific antibodies Continued on next page GR-68535 (9-16) Rituxan® (Rituximab) Medication Precertification Request Aetna Precertification Notification 503 Sunport Lane, Orlando, FL 32809 Phone: 1-866-503-0857 FAX: 1-888-267-3277 Page 2 of 2 (All fields must be completed and return both pages for precertification review) Patient First Name Patient Last Name For Medicare Advantage Part B: FAX: 1-844-268-7263 Patient Phone Patient DOB H. CLINICAL INFORMATION Section 2 - Required clinical information must be completed for ALL precertification requests. Multiple Sclerosis Please indicate which of the following types of Multiple Sclerosis the patient is diagnosed with: Relapsing-Remitting MS Secondary-Progressive MS Primary-Progressive MS Progressive-Relapsing MS Yes No Has the patient had an inadequate response to medications used to treat Multiple Sclerosis? Which of the following MS medications has the patient tried and had a documented failure to? alemtuzumab (Lemtrada) : Please indicate the date range of trial: / / / / Please define the failure of therapy*: Increasing relapses Lesion progression by MRI Worsening of Disability daclizumab (Zinbryta) : Please indicate the date range of trial: / / / / Please define the failure of therapy*: Increasing relapses Lesion progression by MRI Worsening of Disability dalfampridine (Ampyra) : Please indicate the date range of trial: / / / / Please define the failure of therapy*: Increasing relapses Lesion progression by MRI Worsening of Disability dimethyl fumarate (Tecfidera) : Please indicate the date range of trial: / / / / Please define the failure of therapy*: Increasing relapses Lesion progression by MRI Worsening of Disability glatiramir acetate (Copaxone or Glatopa): Please indicate the date range of trial: Please define the failure of therapy*: Increasing relapses Increasing relapses / Lesion progression by MRI fingolimod (Gilenya): Please indicate the date range of trial: Please define the failure of therapy*: / / / - Increasing relapses Please define the failure of therapy*: Increasing relapses / - / / / - / - Worsening of Disability / ___________ Other: ___________ Other: ___________ Other: ___________ Other: / ___________ / Other: ___________ Other: ___________ / Lesion progression by MRI teriflunomide (Aubagio): Please indicate the date range of trial: Other: / Worsening of Disability Lesion progression by MRI / ___________ / Lesion progression by MRI natalizumab (Tysabri): Please indicate the date range of trial: / Worsening of Disability / interferon beta (Avonex, Betaseron, Extavia, Rebif): Please indicate the date range of trial: Please define the failure of therapy*: - Other: Worsening of Disability / / Please define the failure of therapy*: Increasing relapses Lesion progression by MRI Worsening of Disability Other: ___________ * Increasing relapses: defined as two or more relapses in a year, or one severe relapse associated with either poor recovery or MRI lesion progression * Lesion progression by MRI: defined as increased number or volume of gadolinium-enhancing lesions, T2 hyperintense lesions or T1 hypointense lesions * Worsening disability: defined by sustained worsening of Expanded Disability Status Scale (EDSS) score or neurological examination findings Relapsed or refractory hairy cell leukemia Yes No Has the patient had failure of multiple (2 or more) courses of cladribine? Please provide the date range of course #1: Date range: / / / / Please provide the date range of course #2: Date range: / / / / Rheumatoid Arthritis Yes No Does the patient have moderate to severe active rheumatoid arthritis? Yes No Has the patient had an incomplete response to Remicade? If yes, provide the date range: / / / / Yes No Has the patient had an incomplete response to any of the following: Enbrel, Humira or Simponi Aria? Yes No Does the patient have an intolerance or contraindication to 2 of the following: Enbrel, Humira, Remicade, Simponi Aria? Please describe the intolerance or contraindication: ______________________________________ Please provide the name and date ranges of all medication tried: Medication: Dates: / / / / Yes No Will rituximab be used in combination with methotrexate? Sjogren syndrome Yes No Is Sjogren's refractory to corticosteroids and other immunosuppressive agents? Please provide the names and date range of the corticosteroids and other immunosuppressive used: Name(s): _____________________________________________ Date ranges: / / Small lymphocytic lymphoma Waldenström’s macroglobulinemia Opsoclonus-myoclonus-ataxia Yes No Is the opsoclonus-myoclonus-ataxia associated with neuroblastoma? Yes No Is the member refractory to steroids, chemotherapy and intravenous immunoglobulins? Please provide the name and date ranges of the medications tried: Name(s)_________________________ Date: / / / / For Continuation Request: Yes No Has the patient had significant improvement or adequate response after 12 weeks of Rituxan treatment? I. ACKNOWLEDGEMENT Request Completed By (Signature Required): Date: / / Any person who knowingly files a request for authorization of coverage of a medical procedure or service with the intent to injure, defraud or deceive any insurance company by providing materially false information or conceals material information for the purpose of misleading, commits a fraudulent insurance act, which is a crime and subjects such person to criminal and civil penalties. The plan may request additional information or clarification, if needed, to evaluate requests. GR-68535 (9-16)