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Załącznik nr 3 do procedury opracowywania i okresowego przeglądu programów kształcenia Appendix no. 3 to the procedure of development and periodical review of syllabuses Model syllabus for a subject 1. Imprint Faculty name: Faculty of Medicine and Dentistry, Medical University of Warsaw Education program (field of study, level and educational profile, form of studies, e.g., Public Health, 1st level studies, practical profile, full time): English Dentistry Division, 1st level studies, practical profile, full- Academic year: 2016/2017 Module/subject name: Biochemistry with elements of chemistry Subject code (from the Pensum system): 29368 Educational units: time Chair and Biochemistry Department First Faculty of Medicine 02-097 Warsaw, ul. Banacha 1 Phone: +48 (22) 57 20 693 e-mail: [email protected] Head of the unit/s: Prof. dr hab. Anna Barańczyk-Kuźma Study year (the year during which the respective subject is taught): second year Study semester (the semester during which the respective subject is taught): III and IV semester Module/subject type (basic, corresponding to the field of study, optional): basic Teachers (names and surnames and degrees of all academic teachers of respective subjects): Prof. dr hab. Anna Baranczyk Kuźma, prof. dr hab. Iwonna RahdenStaroń, dr Grosicka-Maciąg, dr Magdalena Mielczarek-Puta, lek. Wojciech Graboń ERASMUS YES/NO (Is the subject available for students under the ERASMUS programme?): yes A person responsible for the syllabus (a person to which all comments to the syllabus should be reported) Prof. dr hab. Anna Barańczyk-Kuźma (48 (22) 57 20 693) Number of ECTS credits: 8 Strona 1 z 6 Załącznik nr 3 do procedury opracowywania i okresowego przeglądu programów kształcenia Appendix no. 3 to the procedure of development and periodical review of syllabuses 2. Educational goals and aims Structures, properties and metabolism of substances present in the body: proteins, carbohydrates, lipids, nucleic acids, vitamins, hormones. Control and integration of metabolic pathways. Objectives: 1. To develop a solid understanding of the fundamental chemistry 2. To provide an introduction to the principles of biochemistry that gives the students a command of its concepts. 3. To provide an explanation of the relationship between the three-dimensional structure of macromolecules and their biological activities. 4. To give the insight into understanding how metabolic processes can contribute to explanation of pathological phenomena. 5. To give the students experience in biochemical methodology in order to appreciate the clinical biochemistry techniques as diagnostic tools, and to be able to interpret the results for appropriate diagnosis and follow up of patients. Strona 2 z 6 Załącznik nr 3 do procedury opracowywania i okresowego przeglądu programów kształcenia Appendix no. 3 to the procedure of development and periodical review of syllabuses 3. Initial requirements 1. It is beneficial to read and understand the chemical and biological background before the seminars and laboratory classes 4. Learning outcomes corresponding to the subject A list of course learning outcomes Symbol of course learning outcomes Description of course learning outcomes The reference to programme learning outcomes (number) W1 Function of main elements in metabolic processes B.W1 W2 Electrolyte balance, buffers, and chemical reactions in biological systems. B.W2 W3 Biochemical basis of integrity of human organism B.W3 W4 Structure and functions of important chemical compounds present in human organism: in particular: properties, functions, metabolism and energetical reactions of: proteins, nucleic acids, carbohydrates, lipids, enzymes, vitamines and hormones B.W4 W5 Calcium and phosphates metabolism B.W5 W6 Role and function of body fluids, in particular saliva B.W6 W7 Acid-base equilibrium, transport of carbon dioxide and oxygen in organism. B.W21 W8 Bases of metabolism B.W22 U1 Calculations of concentrations of solutions (percentage, molar), culations of osmolality of body fluids ----- U2 Performance of basic laboratory techniques ------- 5. Forms of classes Form Number of hours Number of groups Lecture 35 1 Seminar 35 1 Practical classes 55 1,7 6. Subject topics and educational contents Lectures: L1. Proteins structures W1; W3; W4 L2 - L3. Enzymes W2; W4 L4. Tissue oxidation W4; W8 L5. Nucleic acids, replication, transcription, translation W4 Strona 3 z 6 Załącznik nr 3 do procedury opracowywania i okresowego przeglądu programów kształcenia Appendix no. 3 to the procedure of development and periodical review of syllabuses L6. Digestion W6 L7. Generation of ATP from glucose W4 L8 - L9. Carbohydrates metabolism W4; W8 L10. Generation of ATP from fatty acids W4 L11 – L12. Lipids metabolism W4; W8 L13. Protein turnover, ureogenesis W4; W8 L14 - L15. Amino acids metabolism W4; W8 L16. Blood W3; W7 L17. Vitamins W4; W8 L18. Hormones W4; W5; W8 Seminars: S1. Proteins W1; W3; W4 S2. Enzymes W2; W4 S3. Tissue oxidation: electron transport chain, oxidative phosphorylation, TCA cycle W4; W8 S4. Structure of nucleic acids, DNA replication, process of transcription and translation W4 S 5 . C arbohydrates metabolism W4; W8 S6. Lipids metabolism W4; W8 S7. Ureogenesis, amino acids metabolism W4; W8 S8. Catabolism of amino acids W4; W8 S9. Blood W3; W7 S10. Vitamins W8 S11. Hormones W4; W5; W8 S12. Summary of metabolism, consultations W8 Practical class: C1. Biochemical calculation W1; W2; U1 C2. proteins W4; U2 C3. enzymes W4; U2 C4. carbohydrates W4; U2 C5. digestive enzymes W4; W6; U2 C6. lipids W4; U2 C7. blood W4; W6; U2 C8. urine constituents W4; W6; U2 7. Methods of verification of learning outcomes Learning outcome corresponding to the subject (symbol) Forms of classes (symbol) W1-W8 W W1-W8 S W1-W8, U1, U2 C Methods of verification of a learning outcome Final exam (MCQ 75 questions) Continuous assessment, intermediate assessment tests during the year – two tests at the end of III and IV semester Continuous assessment Credit receiving criteria At least 55% points At least 55% points Minimum 70% points from all practical classes 8. Evaluation criteria Form of receiving credit in a subject: exam MCQ grade criteria Strona 4 z 6 Załącznik nr 3 do procedury opracowywania i okresowego przeglądu programów kształcenia Appendix no. 3 to the procedure of development and periodical review of syllabuses 2.0 (failed) 0 – 54% of correct answers during final exam. 3.0 (satisfactory) 55 – 64% of correct answers during final exam 3.5 (rather good) 65 – 74% of correct answers during final exam 4.0 (good) 75 – 84% of correct answers during final exam 4.5 (more than good) 85 – 93% of correct answers during final exam 94 – 100 % of correct answers during final exam. Outstanding effects of education 5.0 (very good) 9. Literature Obligatory literature: 1. Biochemistry Lippincott’s Illustrated Reviews, D.R. Ferrier (R.A. Harvey ed.), Wolters Kluwer, Lippincott,Williams & Wilkins, sixth edition. 2. Harpers’ biochemistry, R.K. Murray, D.K. Granner, P.A. Mayers, V.W. Rodwell, Appleton & Lange. Last edition. 3. Biochemistry, a practical guide for laboratory classes. A. Barańczyk-Kuźma, I. Rahden-Staroń, ed. Oficyna Wydawnicza, Medical University of Warsaw, last edition. Supplementary literature: 1. Biochemistry. L. Stryer, W.H. Freeman & Company, New York. 2. Principles of Medical Biochemistry, G. Meisenberg, W.H. Simmons, Elsevier (online access + interactive extras, studentconsult.com). 3. Medical Biochemistry, J.W. Baynes, M.H. Dominiczak, Elsevier, (online access + interactive extras, studentconsult.com). Last edition. 4. Textbook of Biochemistry with clinical correlations, T.M. Devlin, Willey-Liss, Inc. Last edition. 10. ECTS credits calculation Form of activity Number of hours Number of ECTS credits Direct hours with an academic teacher: Lectures 35 1,0 Seminars 35 1,5 Practical classes 55 2,0 Student's independent work (examples of the form of work): Student's preparation for a seminar 35 1,0 Student's preparation for a class 20 0,5 Student's preparation for credits 40 1,0 Student's preparation for an exam 40 1,0 Other (please specify) ---- Strona 5 z 6 ---- Załącznik nr 3 do procedury opracowywania i okresowego przeglądu programów kształcenia Appendix no. 3 to the procedure of development and periodical review of syllabuses 260 8,0 pts 11. Additional Information RULES: Attendance: Student is expected to: - attend all lecture, laboratory classes, seminars and intermediate assessments on time - be prepared for and participate in discussion during seminars and laboratory classes In case of illness, emergency or other excusable absence student has to contact Prof. Iwonna Rahden-Staroń, as soon as possible (no later than within a week). Excused absences will require either prior approval, written verification or doctor’s certificate. Unexcused absences from the laboratory classes, seminars and intermediate assessment/s and not credited intermediate assessments will result in failing the entire course of biochemistry. Evaluation: Laboratory classes: Students knowledge, manual skills, participation and preparedness for the laboratory are awarded with points (from 1 to 6) - 70% of the total number of point give the credit. Only excused absence results in the possibility of the retake at the end of the spring semester (in May). Seminars: Students activity is awarded with grades from 2 to 5. Average grade of 3 (sat) or more is needed to get the credit at the end of the course. More than 3 absences from seminars (in both winter and spring semesters) will result in the retake from all seminar topics at the end of the course (in May). Two intermediate assessments: 55% of correct answers are needed to pass. Unexcused absence (within a week) means failing. Student can get the credit for the whole course if he/she credits laboratory classes, seminars and assessment tests. Retake tests (II and III) are in May. Final exam (in June) is mostly composed of multiple choice questions, however short answer essay, matching and formulas may be included. The grade obtained from the final exam may be increased for students who are very active during seminars, labs and have got high grades from intermediate tests by the head of the Department. Academic honesty: Cheating will not be tolerated! The minimum penalty for cheating will be zero points for a test or exam. Signature of the Head of the Unit Signature of the person responsible for the syllabus Strona 6 z 6