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Stimulus – response Name the 3 kinds of stimuli 1 .Pain, Temp. Pressure, Vibration 2. Change in internal environment 3. Change in internal environment What detects stimuli? Receptors/specialized nerve endings Organization of the Nervous System P314-338 What are the two anatomical divisions of the nervous system? CNS (central nervous system) PNS (peripheral nervous system) Name the functional divisions. Autonomic Nervous System (ANS) Somatic Nervous System - Name the anatomic divisions. CNS - brain, spinal cord and neuroglia cells PNS- peripheral nervous system How many cranial nerves are there? How many spinal nerves are there? 12 pair 31 pair What is the general name of the support cells? Neuroglia cells Is the autonomic functional or anatomic? Functional Define the ANS. a two neuron chain from the CNS to the neuroeffector organ Name the two divisions of the ANS Parasympathetic & Sympathetic Define the Somatic Nervous System. A one neuron chain from the CNS to the neuroeffector organ Functions of the Nervous System p. 334 What are the functions of the nervous system? 7 Perceive and respond to stimuli Coordination and control of body activities Memory Learning based on past experiences Deductive reasoning Inductive reasoning Instinctive behavior 1 Terminology of the Nervous System Table 11.1, p. 335 A sensory neuron is a Afferent neuron Afferent means Information coming in to the system A motor neuron is a Efferent neuron Efferent means Information going out of the system A ganglion is a A collection of neuron cell bodies outside of the CNS A nucleus is a A collection of neuron cell bodies within the CNS Atract is a Grouping of nerve fibers that interconnect regions of the CNS Neurons and Neuroglia p. 338 Table 11.2, p. 341 Name the parts of a neuron. 3 cell body, dendrite, axon AKA for cell body soma What does it contain contains the nucleus or processing center What does a dendrite do? It is the receiving portion of a neuron What does a dendrite contain? Receptors So you could say it is the _____ part of a neuron. Afferent What does an axon do? It is the transmitting portion of a neuron So you could say it is the _____ part of a neuron. Efferent 2 Neuroglia Name the neuroglia cells. 6 Neurolemmocytes Oligodendrocytes Microglia Astrocytes Ependymal Cells Ganglionic Gliocytes Myelination is the Formation of myelin sheath What is a myelin sheath? A lipid layer that covers an axon or dendrite What is myelin made of? myelin is a lipoproteinaceous material composed of regularly altematingmembranes of lipid lamellae and protein What neuroglia is involved in myelination in the PNS? Neurolemmocyte What neuroglia is involved in myeilnation in the CNS? Oligodendrocyte Myelination does what? Provide support and aid in the conduction of nerve impulses Myelin is also found where? Brain, it gives the white matter of the brain and spinal cord (SC) and peripheral nerves their whitish color How does the myelination of the PNS take place? neurolemmocytes grow and wrap around an axon or dendrite What is the outer surf enclosed by a glycoprotein sheath The glycoprotein sheath is called the neurolemmal sheath Each neurolemmocyte covers approximately 1 mm of space on the axon In between each neurolemmocyte there is a gap 3 In between each neurolemmocyte there is a gap This gap is called a Node of Ranvier or neurofibril node Class jfication of Neurons and Nerves - p. 342 How are neurons classified? 3 According to direction of impulse they would be According to direction of impulse travel According to fiber diameter According to Structure afferent or efferent According to fiber diameter they would be Type A fibers Type B fibers Type C fibers Type A fibers are Type B fibers are Type C fibers are Large myelinated, rapid conducting Medium sized with less myelin Small, less myelin, slow According to structure they would be Pseudounipolar Bipolar Multipolar Pseudounipolar neurons are Sensory neurons GSA, GVA Bipolar neurons are Special sensory neurons; SSA, SVA Multipolar Motor neurons; GSE, GVE Definitions of terms Somatic = Visceral = Relating to or involving the skeleton or skeletal (voluntary) muscle Viscera (involuntary) muscle and autonomic innervation 4 According to specific type of tissue innervated p.334 GSA = General Somatic Afferent GSA innervates Sensory for skin, bones, joints GSE = GSE innervates General Somatic Efferent Motor to skeletal muscle GVA = GVA General Visceral Afferent Sensory, pain & stretch from viscera & blood vessels General Visceral Efferent Motor to smooth rn., cardiac m. and Glands • GVE = GVE • SVE = Special Visceral Efferent Somatic motor to SCM and trapezius • SVA = SVA Special Visceral Afferent Sensory from taste and smell • SSA = Special Somatic Afferent Sensory from eye and ear Which of the above do spinal nerves carry? - Spinal nerves are mixed - contain all the “G’s”, Do they contain any special components? NO, contain no special components Which do cranial nerves carry? Can have G or S or a mix of the two Connective tissue covering of a nerve p. 344, figure 11.11 Epineurium surrounds what? Entire nerve Perineurium surrounds Bundles of nerve fibers Endoneurium surrounds Individual nerve fiber 5 Fasciculus = A bundle of nerve fibers Transmission of Nerve Impulse p. 346-348 Appendix #2 Nerve Impulse = movement of sodium and potassium ions along the length of a nerve fiber This results in The creation of a stimulus that excites another neuron or tissue Irritability = Ability of dendrites and cell bodies to respond to a stimulus The stimulus is converted to An electrochemical impulse Conductivity Transmission of an impulse along an axon or dendrite Resting Membrane Potential = Before a nerve fiber can respond to a stimulus it must be polarized. Polarization = exists when there is an electrochemical gradient present between the inside of the cell and the outside of the cell. What does this mean? Positive charge on the outside Negative charge on the inside Which are the positive ions? Sodium ions Which are the negative ions? Potassium ions Which are on the inside of the cell? Potassium ions Which are on the outside? Sodium ions And the cell membrane is a Semi permeable membrane 6 Depolarization = A stimulus causes ions gates in the cell membrane to open When they open what happens? a rapid influx of sodium into the cell which causes a reversal of polarity called depolarization Ion gates are what cause cell membranes to be Semi permeable Does depolarization just happen at one ion gate? NO, a wave of depolarization is conducted down the length of the nerve fiber Repolarization = Sodium/potassium pump pumps sodium back out of the cell and potassium into the cell to re-establish the resting membrane potential. All or None Response = When a stimulus of sufficient strength triggers an action potential the nerve “fires” What is the in between stage Of a nerve firing? The is no in between, it is either Firing or it is at rest Can a nerve impulse travel in two directions? Nerve impulses only travel in one direction Is there a loss of voltage as the wave travels NO to the end of the axon or axon terminus? Threshold = The internal voltage at which the cell will spontaneously depolarize 7 Synapse p. 347, figure 11.15 Define synapse = The connecting point between the axon terminal of the neuron and the cell membrane of a cell Presynaptic neuron = Axon terminal which is sending the infb Postsynaptic tissue = Cell/tissue receiving the info Axon Terminal = Synaptic bulb, knob - distal portion of the axon Synaptic Vesicles = Located in the axon terminal, contain neurotransmitter chemicals(the info) Synaptic Cleft = Gap between the pre and post synaptic cells Threshold = the internal voltage at which the cell will spontaneously depolarize Synapse = A functional connection between the axon terminal (presynaptic neuron) and the cell membrane of (postsynaptic cell) 8 Name three neurotransmitters = 1. Ach = Choline + Acetyl Co A 2. Acetylcholinesterase 3. Norepinephrine IPSP = Inhibitory Post Synaptic Potential Are chloride ions negative or positive? Negative Where are chloride ions ( Cl—) found? Inside the cell/neuron EPSP = Excitatory Post Synaptic Potential Are sodium ions negative or positive? Positive Where are sodium ions (Na+) found? Outside the cell/neuron Resting Membrane Potential = The electrical state of a non-firing neuron This resting potential is due to? An imbalance of charged ions between the inside of the cell and the outside of the cell What kind of charge is on the outside of the membrane? Positive So the inside would be? Negative What does Na+ do in an action potential? Rushes through the membrane, into the cell What does K+ do in an action potential Rushes through the membrane, out of the cell After the action Potential is over what happens to the Na+ & K+? The Na+ is pumped out of the cell & the K+ is pumped back into the cell What is the pump called? Sodium-Potassium Pump 9 What does a Sodium-Potassium Pump use for energy? ATP For every ____Na+ pumped_____ there are — K+ pumped back —. For every 3 Na+ pumped OUT there are 2 K+ pumped back IN. What kind of membrane is it? Selectively permeable membrane It is more permeable to____ than to_____ More permeable to K+ Less permeable to Na+ What are the large negatively charged ions called? Anions Where are they found? Inside the cell/neuron What are they made of? chloride ions ( Cl-) Is the plasma membrane permeable to Cl — NO How many steps in an action potential? 7 Step 1. Adequately intense stimulus Mechanical, Electric or chemical • Stimulus can be? Step 2. Membrane permeability changes and Na+ diffuse into cell Step 3. As Na+ move into cell, the transmembrane potential reaches zero (loss of polarity = depolarization) • This can be called Step 4. Na+ cause inside of cell to become positive in relation to outside = (reversal of polarity) Is this happening all over the cell? No, just at one place. Step 5. The reversal of polarity stimulates the area next to it — which stimulates the area next to it - which stimulates the area next to it - which stimulates the area next to it all the way to the axon terminal 10 Step 6. Back at the point of initial stimulation there is a decrease in permeability of the membrane to Na+ & an increase to K+ • What does K+ now do? Diffuses rapidly out of the cell • This results in? Outside of membrane becoming more positive than the inside. • This is called Repolarization Step 7 Sodium-potassium pump re-establishes Na+ & K to their normal resting levels So the neuron is now ready to be Stimulated to the point of another ACTION POTENTIAL i.e. Step 1. The Spinal Cord p. 372 - 379 Where is the spinal cord located? In the vertebral canal (neural canal) It extends from The foramen magnum to L1 Conus medullaris = Tapered end of spinal cord Filum terminale = Pin mater, attaches to coccyx Cauda equina = Collection of spinal nerve roots Spinal segment = A section of the cord where a pair of spinal nerves arise Basic Anatomy of the Spinal Cord The meninges are composed of Where does the dural sac end? 3 layers 1. dura mater 2. arachnoid 3. pia mater At S3 11 Denticulate ligament = sawtooth like attachments of the pia to the dura How many are there? 20-22 What do they do? Serve to suspend the spinal cord within the dural sac. They extend from The foramen magnum to T12 -LI White matter consists of bundles of myelinated sensory and motor neurons Anterior median sulcus Grove that run down the anterior of the spinal cord Posterior median sulcus = Grove that run down the posterior of the spinal cord Funiculi = Means cord or column of white Matter How many are there? 6 Name them Anterior funiculi – 2 Posterior funciculi – 2 Lateral Funiculi - 2 Tract = A bundle of nerve fibers within the central nerves system (CNS) 12 Ascending tracts = Sensory Descending tracts = Motor Gray matter is composed mostly of Neuron cell bodies and interneurons Interneuron = Combinations or groups of neurons between sensory and motor neurons that govern coordinated activity. Dorsal horn AKA Posterior horn Composed of? Incoming axons of sensory neurons And carries GSA, GVA Ventral horn AKA Anterior horn Composed of? GSE neuron cell bodies Lateral horn = GVE neuron cell bodies (T1 to L2) Gray commissure = A bundle of nerve fibers passing from one side to the other in the brain or spinal cord Central canal Central canal of spinal cord How many enlargements does the spinal cord have? 2 Name them Cervical and Lumbar Functions of the spinal cord Ascending - sensory Impulse conduction Descending- motor Reflex integration Spinal segment = Pair of spinal nerves And they emerge from the spinal cord through IVF How many spinal nerves are there? 31 pairs of spinal nerves How many spinal segments are there? 31 spinal segments 13 How are spinal nerve formed? formed by the union of the Ventral root (motor) and the Dorsal root (sensory) Rootlets combine to form Roots What rootlets are there? Ventral Rootlets and Dorsal Rootlets Roots join to form The spinal nerve at the IVF Dorsal Root carries GSA, GVA Dorsal Root Ganglion are composed of? Pseudounipolar neuron cell bodies Ventral Root are composed of? GSE, GVE Spinal segment Spinal segment = A cross sectional segment of the spinal cord that gives rise to a pair of spinal nerves (one spinal nerve from each side of the cord) Spinal segments have a relationship to? Vertebral levels i.e. a portion of the cord housed within the confines of a vertebra.: For example Cl spinal segment is in the Neural canal of Atlas L2 spinal segment is in the Neural canal ofTi 1 vertebra S4 spinal segment is in the Neural canal ofLi vertebra Bell-Magendie Law = The dorsal root of a spinal nerve carries sensory information, the ventral root carries motor infbrmation Does the ant. or post. root have an enlargement? Post. What is the enlargement called? Spinal gangion 14 The Spinal Nerve p.400-401 1YF = The Intervertebral Foramen Rule for naming Spinal Nerves: Cervical - according to the vertebra they exit above ie. C3 exits the spinal cord superior to the third cervical vertebra, between C2 and C3 All others - according to the vertebra they exit below ie. T4 exits between T4 and T5 vertebra. Branches of a Spinal Nerve What does a spinal nerve do after it leaves the IVF? Branches These branches are called? Recurrent meningeal, Sinuvertebral, meningeal ramus Dorsal ramus o medial branch o lateral branch Rami communicantes o Gray ramus - GVE o White ramus - GVE, GVA Ventral ramus o plexus o intercostal nerves Dorsal Ramus Medial branch o superior to T6 sensory o inferior to T6 motor Lateral branch o superior to T6 motor o inferior to T6 sensory Rami communicantes Associated with the ANS 15 White rami connects with? The spinal nerve to the paravertebral ganglia Gray rami connects with? The paravertebral ganglia to the spinal nerve Ventral Ramus Tissues innervated - supply motor, sensory and sympathetic fibers to the anterior and lateral muscles ans skin of the neck and trunk and all the muscles and skin of the limbs, including the superficial back muscles • Form plexuses • T1-T12 intercostal nerves Roots and Rami? Be able to d the following terms: Spinal nerve = The nerves emerging from the spinal cord How many are there? There are 31 pairs What do each attach to? The cord by two roots, anterior and posterior, or ventral and dorsal The latter is provided with A circumscribed enlargement, the dorsal root (spinal) ganglion The two roots unite in the? Intervertebral foramen (IVF) The mixed spinal nerve almost immediately does what? Divides again into ventral and dorsal primary rarni, The former supplies? The anteroläteral trunk and the limbs, The latter supplies? The true muscles and overlying skin of the back. Ventral root = The motor root of a spinal nerve Dorsal root = The sensory root of a spinal nerve, having a dorsal root ganglion containing the nerve cell bodies of the fibers conveyed by the root in its distal end 16 Ventral rami = The motor root of a spinal nerve Spinal nerve root = Rami communicantes • Dorsal rami • Meningeal rami The Cervical Plexus p. 401, Table 12.3 The Cervical Plexus is composted of? Cl— C4, mostly Ventral rami of C2,3 and 4 Are these branches sensory or motor? Both Sensory branches Name the four Superficial Cutaneous Branches Lesser Occipital Nerve Greater Auricular Nerve Transverse Cervical Nerve Supraclavicular Nerves Lesser Occipital Nerve is derived from? C2,3 It innervates? Skin posterior to the auricle and lateral portion of the occipital region Greater Auricular Nerve is derived from? C2,3 It has ____branches? 2 branches Name the branches Anterior branch - skin over parotid salivary gland Posterior branch - skin over the mastoid process and ear lobe 17 Transverse Cervical Nerve is derived from? C2,3 - skin of anterior Neck Supraclavicular Nerves is derived from? C3,4 How many branches does it have? 3 branches Name them. Medial branch — Skin from clavicle to the midline Intermediate branch--skin of anterior chest wall Lateral branch — skin over the shoulder Motor branches Ansa cervicalis is derived from? C 1,2,3 It innervates? Omohyoid Sternohyoid Stemothyroid Phrenic Nerve is derived from? C3,4,5 It innervates? The diaphragm Other Cervical nerves: Suboccipital Nerve is derived from? Dorsal ramus of Cl It is motor to? The muscles of the SOT, it is sensory to? NO cutaneous sensory What are the muscles of the SOT? Obliquues Capitis Superior Obliquues Capitis Inferior Rectus Capitis Post. Minor 18 Greater Occipital Nerve is derived from? Dorsal ramus of C2 It is sensory to? The posterior scalp It is motor to? Splenius m. The action of the splenius m. is? One side contraction - Head rotates and extendss Two side contraction- extend head & neck Third Occipital Nerve is derived from? Dorsal ramus of C3 it is sensory to? Medial branch is sensory to a small area of the posterior scalp The Brachial Plexus p. 401 - 404, Table 12.4 The formation of the plexus? C5,6,7,8,T1 Spinal Nerve Roots = AKA ventral rami of spinal nerve, AKA nerve root 19 The Brachial Plexus is made of? Trunks Divisions Cords Terminal branches Roots = Ventral rami of C5 to Ti Trunks are formed by? The convergence of roots How many trunks are there? 3 Name them Superior Middle Inferior Superior is composed of? Ventral rami of C5 and C6 Middle is composed of? Continuation of C7 Inferior is composed of? Ventral rami of C8 and Ti Divisions Divisions derived from? • anterior - innervate fiexors • posterior - innervate extensors The trunks, 2 per trunk Cords are named in association? With the axillary a Posterior cord is composed of? All 3 posterior divisions Lateral cord is composed of? Anterior divisions of upper and middle trunks, contains fibers for C5,6 and 7 Medial cord Continuation of the anterior divisions of the lower trunk, fibers from C8 and T1 20 Supraclavicular Branches of the Brachial plexus Dorsal scapular n. is composed of? C5 It innervates? Rhomboid mm. Levator scapulae m. Long Thoracic n. is composed of? C5,6,7 It innervates? Serratus anterior m. Nerve to the subclavius m. is composed of? C5,6 It innervates? Subclavius in. Suprascapular n.. is composed of? C5,6 It innervates? Supraspinatus m.. and Infraspinatus m. Infraclavicular Branches of the Brachial Plexus Lateral Cord is composed of? C5,6,7 Lateral pectoral n. is composed of? C5,6,7 It innervates? Pectoralis major m. Musculocutaneous a is composed of? C5,6,7 It innervates? Biceps brachii rn., Coracobrachialis m., Brachialis m. lateral antebrachial cutaneous a is sensory to? Skin of lateral forearm Lateral root of the median n.. is composed of? C5,6,7 Medial Cord is composed of? C8, Ti Medial pectoral n.. is composed of? C8, Ti It innervates? Pectoralis maj.& minor mm Medial Brachial Cutaneous a is composed of? C8, Ti 21 It innervates? Skin of medial & posterior Arm 22 Medial Antebrachial Cutaneous n. is composed of? C8, Ti It innervates? Skin of medial & posterior aspect of forearm Ulnar n. is composed of? C8, Ti It innervates? Flexor carpi ulnaris in., flexor digitorum profundus in., most of the muscles of the hand, skin of the medial hand, little finger and medial half of ring finger Medial Root of Median n. is composed of? C8, Ti It innervates? Flexors of the carpus and digits, except flexor carpi ulnaris In., lateral 2/3’s of the hand and fingers, tips of thumb, index and middle fingers and lateral aspect of the tip of the ring finger, some muscles of the hand (abductor pollicis brevis in.,flexor pollicis brevis in., opponens pollicis m., and lateral lumbrical m. Posterior Cord is composed of? C5,6,7,8,Ti Upper subscapular n. is composed of? C5,6 It innervates? Subscapularis m. Thoracodorsal n. is composed of? C6,7,8 It innervates? Latissimus dorsi m. Lower subscapular n. is composed of? C5,6 It innervates? Subscapularis & Teres major. 23 Axillary n. is composed of? C5,6 It innervates? Deltoid & Teres minor m., sensory from skin over deltoid m. Radial n. is composed of? C5,6,7,8,T1 It innervates? Extensor muscles of the arm, forearm, carpus and digits; Brachioradialis m,. Supinator m., and the lateral portion of the Brachialis m., Sensory to the skin of the posterior arm and forearm, lateral 2/3’s of the hand and fingers over the proximal and middle phalanges Lesions of the Brachial Plexus Erb-Duchenne Palsy involves what nerve roots? What would you visually observe? C5,6 Excessive displacement of the head to the opposite side and depression of the shoulder on the same side. Dorsal scapular n. damaged you would see? Dropped shoulder and scapula falls laterally Suprascapular n. damaged you would see? Loss of lateral rotators Axillary n. damaged you would see? Humerus rotates medially due to loss of lateral rotators & unopposed pectoralis maj Musculocutaneous n. damaged you would see? Paresis of muscles of the anterior arm and forearm pronates due to loss of biceps brachii m. “Waiter’s tip” 24 Klumpke’s Palsy What is the result of excessive traction or abduction of the arm as is seen in a fail when one grasps an object to try and break the f or when a mother jerks a child by one arm called? Kluinpke’s Palsy Damage to T1 results in? Inability to abduct the fingers (not the thumb), atrophy of the small muscles of the hand and loss of sensation along medial aspect of arm Damage to the Long Thoracic N. will injure what nerves roots? C5,6,7 What nerve innervates the serratus anterior m. Loss of innervation to the serratus anterior would result in? This is called Damage to the Radial Nerve This is seen in Long Thoracic N. posterior deviation of the vertebral border of the scapula “Winged Scapula” Radical mastectomy or blows to the posterior triangle of the neck The redial nerve is composed of’? C5,6,7,8,T1 Clinical signs depend on? Where nerve is damaged It is commonly damaged in? Midshaft humeral fractures It is also seen with? Improper use of a crutch “frogging” drunkard paralysis, AKA church pew paralysis “wrist drop” 25 Median Nerve Damage indicated by? Numbness and pain in the lateral aspect of the palmar surface of the hand, inability to pronate the forearm, weakness in the thumb and severe paresis in carpal flexion Clinical signs depend on? Where it is damaged Commonly seen in? Suicide attempts — wrist slashing Carpal tunnel syndrome The carpal tunnel is formed by? The anterior surfaces of the carpal bones and the flexor retinaculum Carpal tunnel syndrome is caused by? Compression of the median nerve in the carpal tunnel Clinically you will find? Burning “pins and needle” sensation in the palmar aspect of the lateral 3 &1/2 fingers and paresis of the thenar muscles. If there is NO loss to sensation over the thenar eminence? No palmar branch the involvement Pronator teres syndrome The median n. penetrates between? Same clinical picture as Carpal tunnel EXCEPT? What is effected? The two heads of the pronator teres m. just below the elbow and can become entrapped there There is loss of sensation over the thenar eminence because affects entire length of median nerve Palmar branch of median nerve affected 26 The Lumbar Plexus p. 404 - 405, Table 12.5 The Lumbar Plexus is composed of? The Femoral Nerve is composed of’? The Femoral Nerve is motor to? L1,2,3,4 L2,3,4 Iliacus m. Pectineus in. Sartorius in. Quadriceps The Femoral Nerve is sensory to? Skin of anterior and medial thigh Saphenous n. is a branch of? Femoral n. It innervates? The skin of medial aspect of thigh and leg and foot The Obturator Nerve is composed of? L2,3,4 It is motor to? Adductor longus in. Adductor brevis in. Gradiis in., Obturator extemus in. Adductor magnus m. it is sensory to? Skin of the medial thigh The Ilioinguinal Nerve is composed of? Li It is motor to? Part of the internal and external abdominal obliques and transverse abdominis m. It is sensory to? Skin of upper medial aspect of the thigh, foot of the penis and scrotum, labia majora and mons pubis 27 The Iliohypogastric Nerve is composed of? Li It is motor to Muscles of the Anterolateral abdominal wall It is sensory to? Skin of the lower abdomen and buttock The Genitofemoral Nerve is composed of? L1,2 How many branches does it have? 2 branches It is motor to? Genital branch —cremaster m. It is sensory to? Femoral branch — skin of middle anterior surface of thigh, scrotum - in male and labia majora in female Lateral Cutaneous Femoral n. is composed of? L2,3 It is sensory to? Skin over the lateral and anterior thigh Lumbosacral trunk is composed of? Inferior portion of L4,5 The Sacral Plexus, L4,5,Sl,2,3,4 p. 405 - 409, Table 12.6 The Sacral Plexus is composed of? L4,5,S1,2,3,4 The Superior Gluteal Nerve is composed of? L4,5,Sl It is motor to? gluteus minimus and medius mm. And tensor f latae it is sensory to? no cutaneous sensory branch 28 The Inferior Gluteal Nerve is composed of? L5,S1,2 It is motor to? Gluteus maximus iii. It is sensory to? No cutaneous sensory branch The Sciatic Nerve The Sciatic Nerve is composed of? L4,5,S1,2,3 The Sciatic Nerve is actually? 2 nerves in one neural sheath. It splits into its? Two respective divisions just proximal to the knee. As the sciatic nerve, it descends? Through the posterior thigh It sends branches to the? Hamstrings and adductor magnus m. The Tibial Nerve The Tibial Nerve is composed of? L4,5,S 1,2,3 It is motor to how many muscles? 11 Name them. Semitendinosus Semimembranosus mm. Long head of biceps femoris m. Adductor magnus m. Gastrocnemius m Soleus m. Plantarism. Popliteus m. Tibialis posterior m. Flexor digitorum longus m. Flexor hallucis longus m. Medial and lateral plantar nn innervate? Muscles of the foot and sensory to the skin over the plantar surface of the foot Cutaneous sensory Skin of the posterior leg 29 The Common Peroneal Nerve The Common Peroneal Nerve is composed of? L4,5,S 1,2 It is motor to? Short head of biceps femoris The nerve then comes from the Posterior side and crosses laterally over the head of the fibula Where it then divides? Into 2 branches: Name the branchs. Superficial peroneal n. Deep peroneal n. The superficial peroneal is motor to? Peroneus longus Peroneus brevis The superficial peroneal is sensory to? Skin over the distal 1!3 of the anterior aspect of the leg and dorsum of the foot The deep peroneal n. is motor to? Tibialis anterior m Extensor hallucis longus m Extensor digitorum m Peroneus tertius m. The deep peroneal is sensory to? A small area of skin on the dorsum of the foot between the first and second toes The Pudendal Nerve The Pudendal Nerve is composed of? S2,3,4 It is motor muscles to the? perineum, levator ani u external anal sphnicter m., external urethral sphnicter in. Is it sensory to? Skin of the penis and scrotum in male; clitoris, labia majora and minora and vagina in female 30 Coccygeal Plexus The Coccygeal Plexus is composed of? S(4), 5, Cy 1 Does it have branchs? Yes Name them. Branch to the coccygeus m. Branch to the skin over the coccyx Veterbral levels for Intercostal Nerves? T2-T12 Dermatomes — — — — greater occipital nerve - C2 C3,4 upper and lower extremities T4 - nipple Reflex Arc and Refl Give the components of a simple reflex arch: Receptor Sensory neuron Association neuron Motor neuron Effector organ Give anexample of a Ipsilateral Reflexic Arc. Knee jerk So if a reflex is absent, where is the problem? Reflexes are graded as to: Normal Hyperreflexia Hyporeflexia The End of the Nervous System Have a real nice day Review questions: 1) To detect stimuli, what must a cell posses? 2) What are the components of the PNS? Receptors/specialized nerve endings Sensory nerves Motor nerves Mixed nerves 31 3) What direction does information travel in a spinal nerve? Both ways 4) C1assif neurons according to the number of processes they have and tell me what kind of information each one carries. Pseudounipolar neurons are sensory neurons GSA, GVA Bipolar neurons are special sensory neurons; SSA SVA Multipolar are motor neurons; GSE, GVE 5) Give me the location of the neuron cell body that carries, GSA info., GSE info., GVE info., SSAinfo., SVAinfo.,etc. Within the spinal cord 6) Give me examples of tissues innervated by neurons carrying GSA, GVA, GSE, GVE, SSA, SVA info GSA = Skin, bones, muscles, joints.GVA = Visceral organs & blood vessels GSE = Skeletal muscle GVE = Carduac muscle, Glands, Smooth muscle w/in visceral organs SSA = Eyes & ear 7) Is most of the potassium of the body found in or outside of the cell? Inside 8) Define resting membrane potential Resting Membrane Potential = The electrical state of a non-firing neuron This resting potential is due to? An imbalance of charged ions between the inside of the cell and the outside of the cell 9) What is a quantum? A certain definite amount. 10) What does EPSP and IPSP mean? Excitatory Post Synaptic Potential Inhibitory Post Synaptic Potential 11) Define threshold. The internal voltage at which the cell will spontaneously depolarize 12) Name the layers of the meninges in order from superficial to deep Dura mater Arachnoid Pin mater 32 13) What are denticulate ligaments? Sawtooth like attachments of the pia to the dura 14) What makes up the white matter sensory and of the spinal cord? bundles of myelinated motor neurons 15) What kind of neuron is associated with the DRG? Sensory 16) What kind of information is carried in the dorsal root of a spinal nerve? Information coming into the CNS 17) What are the “4” branches of a spinal nerve and what does each one innervate? Meningeal branch — Innervates Meninges, Vertebrae, Vertebral ligaments. Post. Ramus Innervates Muscles Joints Skin of back along spinal column Anterior Ramus Innervates Muscle & skin on lateral & anterior side of trunk Combinations of ant. rami innervate the limbs Rami Communicantes Innervates Two branches, white & gray, go to sympathetic trunk ganglion Gray is composed of White is composed of umnyelinated fibers myelinated fibers 18) What forms the spinal nerve? Post & ant. spinal roots 19) What branch of the spinal nerve forms the plexuses? Ant. raini combine & then split as networks of nerve fibers, these are referred to as “Plexuses” Exception T2 — T12 33 20) What is the association of the sensory branches of the cervical plexus to the SCM? 21) Know the named nerves in the cervical region derived from dorsal rami, Ic. suboccipital nerve. 22) Know the spinal nerves, which contribute to the formation of the branchesof the cervical plexus. Cl — C4 and part of C5 23) Know the spinal nerve roots that form the brachial plexus. C5 — Ti 24) Discuss the formation of the basic skeleton of the brachial plexus. Roots — Trunks — Ant, divisions - Post. divisions 25) Flexor muscles are innervated by _____ divisions of the BP. 26) Tell me the spinal nerve roots that contribute to the formation of the cords of the BP. 27) List the branches off of the cords of the BP. 28) How are the cords associated with the axillary artery? 29) To prevent abduction of the humerus, what nerve roots would I have to cut? 30) To stop flexion of the elbow, what nerves would I have to cut? 31) Tell me the basic motor innervation of the muscles of the upper limb. 32) What nerve roots contribute to the formation ofi thoracodorsal nerve, suprascapular nerve, lower subscapular nerve, dorsal scapular nerve, long thoracic nerve, ulnar nerve, axillary nerve, median nerve, etc. 33) How do you differentiate carpal tu8nnel syndrome from pronator teres syndrome? 34) Tell me the motor innervation of the muscles of the lower limb. 35) What muscles flex the knee and what nerve(s) innervate them? 36) What spinal nerves contribute to the formation of the branches of the lumbar plexus? 37) What muscles are innervated bythe femoral nerve, tibia! nerve, deep peroneal nerve, superficial peroneal nerve, superior gluteal nerve, inferior gluteal nerve, obturator nerve, etc. 34 38) What is a dermatome? 39) Give the components of a typical reflex arch. 40) Which primary vesicle gives rise to the midbrain? 41) What are the components of the diencephalon? 42) Name the dural fold that separates the cerebrum from the cerebellum. 43) Where in the CNS do you find CSF? 44) Which cranial nerves carry taste information? 45) Which cranial nerves carry GSA information from the face and structures of the face? 46) To stop extension of the knee, what nerve would I have to cut? 47) To stop extension of the hip joint, what nerves would I have to cut? 48) What muscles medially rotate the humerus? 49) What muscles retract the scapula? 50) What muscles laterally rotate the hip? 35 36