Download Vijay Vedula - Stanford University

Vijay Vedula
Contact
Information
Department of Pediatrics,
Stanford University,
475 Via Ortega, Suite 060,
Stanford, CA-94305.
Mobile: (713) 826-7183
Email: [email protected]/
[email protected]
Research
Interests
Aerodynamics, Biomechanics, Cardiovascular Flows, CFD & Numerical Methods, Fluid Structure
Interaction, Medical Image Analysis, Multiphase flows, Parallel Computing, Turbulence.
Education
Johns Hopkins University, Baltimore, USA
Ph.D., Mechanical Engineering
Jan 2015
Indian Institute of Technology, Kanpur, India
M.Tech., Aerospace Engineering
Jun 2009
National Institute of Technology, Tiruchirapalli, India
B.Tech., Mechanical Engineering
Research
Experience
May 2007
Postdoctoral Research Assistant
Department of Pediatrics, Stanford University
Mechanical and Aerospace Engineering, University of California San Diego
July 2015 - present
Feb 2015 - Jul 2015
– CAP-CHD Project, NIH-funded, Collaboration with UCSD: The project aim is to develop a
hemodynamic database of congenital heart disease (CHD) patients and in particular, singular
ventricle physiology patients as a part of the cardiac atlas project (CAP).
– The project is used a gateway to answer other interesting hemodynamic questions of single
ventricle physiology patients that is currently lacking especially in terms of disease progression
and ventricular remodeling effects.
– Methods will be developed for 4D image-based blood flow modeling of heart chambers based
on Arbitrary Lagrangian-Eulerian (ALE) formulation and stabilized variational multiscale finite
element methods (FEM).
– Understanding cardiac morphogenesis using embryonic zebrafish, NIH-funded, Collaboration with
UCLA, USC and UCSD: Embryonic zebrafish heart models are used to develop insights into
cardiac morphogenesis. Simulations are used to test the hypothesis that shear stress mediated
Notch signaling pathway leads to ventricular trabeculae formation.
– Contribute to the team by incorporating the above developed methods into the open-source
cardiovascular flow modeling software, Simvascular (http://simvascular.github.io/).
Graduate Research Assistant, Johns Hopkins University
Aug 2010 - Jan 2015
Ph.D. Dissertation: Image-based Computational Modeling of Intracardiac Flows
– Developed a framework for 4D image-based modeling of blood flow in heart using Immersed
Boundary Method (IBM) based formulation.
– Investigated the hemodynamical impact of left atrium, mitral valve, and ventricular trabeculae
on the ventricular filling and blood transport. This work has significantly improved the current
understanding of blood transport phenomena in the ventricle.
– Comprehensively validated the flow solver for blood flow simulations in ventricles with invitro
experiments performed at University of Cagliari, Italy.
– Developed fully parallelized (MPI) Navier-Stokes flows solvers using various formulations and
relevant CFD tools for post-processing. Technical knowledge was shared between the team.
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Graduate Student, Indian Institute of Technology, Kanpur
Aug 2007 - Jul 2009
Thesis: DNS of high Reynolds number transitional flows
– Investigated effects of surface roughness and transition enhancement on flows over airfoils at high
Reynolds numbers using DNS.
– Performed numerical simulations and stability analysis of lid-driven cavity flow. This work
employs novel application of proper orthogonal decomposition (POD) for non-linear stability
analysis.
– Analyzed numerical schemes using Fourier analysis with respect to amplification and dispersion
relation preserving (DRP) properties.
– Developed fully parallelized flow solver using highly accurate compact difference methods.
Leading edge flow control past airfoil, N.I.T. Tiruchirapalli
Dec 2006 - May 2007
– Studied aerodynamic characteristics of an airfoil due to a rotating cylinder at its leading edge.
– Flow simulations were performed using FLUENT commercial CFD software.
Professional
Experience
GE India Technology Center, Bangalore, India
Dec 2009 - Aug 2010
Heat Transfer and Fluid Systems Design (HTFSD) Engineer
– Aircraft jet engine heat transfer analysis - contributed to HTFSD team by performing heat
transfer and blade displacement analysis of rotor/stator blades in the high pressure compressor
of GEnx-2B engine.
Tridiagonal Solutions Private Limited, Pune, India
Aug 2009 - Dec 2009
CFD Engineer
– Worked as an analyst and developer of OpenFOAM.
– Integrated OpenFOAM with WindNinja- software that is used to simulate atmospheric flows over
rough terrains.
– Simulated and validated atmospheric flows over rough terrains using OpenFOAM and FLUENT.
– Extended OpenFOAM solver abilities to account for roughness in turbulent flows.
Professional
Activities
– Reviewer : Journal of Computational Physics, Journal of Fluid Mechanics, Computers and Fluids, Journal of Biomechanical Engineering, Annals of Biomedical Engineering, and International
Journal for Numerical Methods in Biomedical Engineering.
– Teaching Assistant for Introduction to Fluid Mechanics and Advance Mathematical Methods for
Engineers- duties involved preparing assignment solutions, grading, and consulting during office
hours.
– Member of American Physical Society (APS).
Honors and
Awards
– Gordon L. and Beatrice C. Bowles Fellowship, Johns Hopkins University, 2010.
– I.I.T. Kanpur Academic Excellence Award (batch topper), 2007-2009.
– GE Foundation Scholar-Leader scholarship awarded by the General Electric Foundation and
Institute of International Education, 2008.
– Ranked 22nd among ¿150,000 in the common entrance test for undergraduate admission, 2003.
Skills
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Programming: Fortran, C, C++, Matlab, Linux Shell
Parallel computing: MPI, OpenMP, Intel MIC programming, CUDA
Commercial CFD software: OpenFOAM, Fluent, CFX, Comsol, Star-CCM+
Post-processing: Tecplot, Paraview, VisIt, Ensight, Excel
Image processing: Simvascular, Mimics, MIPAV, ITK-Snap
Computational Methods: Finite-Difference (FD), Finite-Element (FEM), Finite-Volume (FVM),
Immersed Boundary Methods (IBM) and Arbitrary Lagrangian-Eulerian (ALE) methods.
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Selected
Coursework
Fluid Dynamics-I, II
Numerical Methods
Advanced Computational Fluid Dynamics
Hydrodynamic Stability
Image Processing
Convection
Turbo Machines
Aerodynamics I, II
Advance Mathematical Methods for Engineers
Finite Element Method
Turbulence
Medical Image Analysis
Heat and Mass Transfer
Compressible Fluid Flow and Jet Propulsion
Publications
– Mittal, R., Seo, J. H., Vedula, V., Choi, Y. J., Liu, H., Hwang, H., Jain, S., Younes, L., Abraham, T., and George, R., Simulation of cardiac hemodynamics for the diagnosis and treatment
of heart diseases: Current status and future outlook, (submitted) J. Comput. Phys.
– Vedula, V., George, R., Younes, L., and Mittal, R., Hemodynamics in the left atrium and its
effect on ventricular flow patterns, J. Biomech. Eng.), doi:10.1115/1.4031487, 137(11):111003,
2015.
– Choi, Y. J., Constantino, J., Vedula, V., Trayanova, N., and Mittal, R., A new MRI-based model
of heart function with coupled hemodynamics, Front. Bioeng. Biotechnol., doi:10.3389/fbioe.2015.00140,
3(140), 2015.
– Vedula, V., Seo, J. H., Lardo, A.C., and Mittal, R., Effect of trabeculae and papillary muscles
on the hemodynamics of the left ventricle, Theor. Comput. Fluid Dyn., doi:10.1007/s00162-0150349-6, 2015.
– Seo, J. H., Vedula, V., Abraham, T., Lardo, A. C., Dawoud, F., Luo, H., and Mittal, R., Effect
of the mitral valve on diastolic flow patterns, Phys. Fluids, 26(12):121901-14, 2014.
– Vedula, V., Fortini, S., Seo, J. H., Querzoli, G., and Mittal, R., Computational modeling and
validation of intraventricular flow in a simple model of the left ventricle, Theor. Comput. Fluid
Dyn., doi:10.1007/s00162-014-0335-4, 28(6):589-604, 2014.
– Choi, Y. J., Vedula, V., and Mittal, R., Computational study of the dynamics of a bileaflet
mechanical heart valve in the mitral position, Ann. Biomed. Eng., 42(8):1668-1680, 2014.
– Seo, J. H., Vedula, V., Abraham, T. et al., Multiphysics computational models for cardiac flow
and virtual cardiography, Int. J. Num. Meth. Biomed. Eng., 29(8):850-869, 2013.
– Zheng, X., Seo, J. H., Vedula, V., Abraham, T., and Mittal, R., Computational modeling and
analysis of intracardiac flows in simple models of the left ventricle, Eur. J. of Mech.- B/Fluids
35:31-39, 2012.
– Sengupta, T. K., Vijay, V. V. S. N.,, and Singh, N., Universal instability modes in internal
and external flows, Comput. Fluids 40(1):221-235, 2011.
– Sengupta, T. K., Rajpoot, M. K., Saurabh, S., and Vijay, V. V. S. N., Analysis of anisotropy of
numerical wave solutions by high accuracy finite difference methods, J. Comput. Phys. 230(1):2760, 2011.
– Sengupta, T. K., Vijay, V. V. S. N., and Bhaumik, S., Further improvement and analysis of CCD scheme: dissipation discretization and de-aliasing properties, J. Comput. Phys.
228(17):6150-6168, 2009.
– Sengupta, T. K., Lakshmanan, V., Vijay, V. V. S. N., A new combined stable and dispersion
relation preserving compact scheme for non-periodic problems. J. Comput. Phys. 228(8):30483071, 2009.
International
Conference/
Symposium
Presentations
– Vedula, V., Seo, J. H., Shoele, K., George, R., Younes, L., and Mittal, R., Image-based flow
modeling in a two-chamber model of the left heart, 67th Annual DFD Meeting, APS, San Francisco, CA, USA, 2014.
– Seo, J. H., K. Shoele, Vedula, V., and Mittal, R., Simulation of Intraventricular Flows with
Physiological Mitral Valve Models, 7th World Congress of Biomechanics, Boston, MA, USA,
2014.
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– Vedula, V., and Mittal, R., Image based modeling of left-ventricular flows, CEAFM-Burger’s
Symposium, University of Maryland, College Park, MD, USA, 2014.
– Vedula, V., Seo, J. H., and Mittal, R., Effects of trabeculations on the hemodynamics of the
left ventricle: a computational study, 66th Annual DFD Meeting, APS, Pittsburgh, PA, USA,
2013.
– Seo, J. H., Vedula, V., George, R., and Mittal, R., Coupled hemodynamic-biochemical modeling
of thrombus formation in infarcted left ventricles, 66th Annual DFD Meeting, APS, Pittsburgh,
PA, USA, 2013.
– Vedula, V., Seo, J. H., Lardo, A., Abraham, T., and Mittal, R., Modeling of blood flow in normal
and diseased left-ventricles, 2013 SIAM Conference on Computational Science and Engineering,
Boston, MA, USA, 2013.
– Seo, J. H., Vedula, V., and Mittal, R., Multiphysics computational models for cardiac flow and
virtual cardiography, European Congress on Computational Methods in Applied Sciences and
Engineering (ECCOMAS 2012), J. Eberhardsteiner et al. (eds.) Vienna, Austria, 2012.
– Vedula, V., Seo, J. H., Fortini, S., Querzoli, G., and Mittal, R., Computational modeling of the
effects of myocardial infarction on left ventricular hemodynamics, 65th Annual DFD Meeting,
APS, San Diego, CA, USA, 2012.
– Vedula, V., Seo, J. H., Zheng, X., Abraham, T., and Mittal, R., Computational modeling
and analysis of intracardiac flows in normal and diseased hearts, CEAFM-Burger’s Symposium,
University of Maryland, College Park, Maryland, USA, 2012.
– Seo, J. H., Vedula, V., Eslami, P., Mittal, R., and Abraham, T., Computational fluid dynamics
based analysis of cardiovascular flows and implications for diagnosis and surgical planning, Johns
Hopkins Heart and Vascular Institute’s 3rd Annual Cardiovascular Research Retreat, 2012.
– Vedula, V., Seo, J. H., and Mittal, R., Virtual cardiac surgery using CFD: application to
septal myectomy in obstructive hypertrophic cardiomyopathy, 64th Annual DFD Meeting, APS,
Baltimore, Maryland, USA, 2011.
– Vedula, V., Seo, J. H. et. al, Computational modeling and analysis of intracardiac flows in
normal and diseased hearts, 2011 BMES Annual Meeting, Hartford, CT, USA, 2011.
– Vijay, V. V. S. N., Singh, N., Sengupta, T. K., Computing internal and external flows undergoing instability and bifurcations, 5th M.I.T. Conference on Computational Fluid and Solid
Mechanics, Focus: Advances in CFD, M.I.T., Cambridge, MA, USA, 2009.
References
Prof. Alison Marsden
Cardiovascular Biomechanics Computation Lab
Department of Pediatrics,
Department of Bioengineering,
Institute of Computational and Mechanical Eng.
Stanford University,
Stanford, CA, USA
email: [email protected]
Dr. Jeffrey Feinstein
Dunlevie Family Professor of Pulmonary
Vascular Disease,
Department of Bioengineering,
Department of Pediatrics,
Stanford School of Medicine,
Stanford, CA, USA
email: [email protected]
Prof. Rajat Mittal
Flow Physics and Computation Lab,
Department of Mechanical Engineering,
Johns Hopkins University,
Baltimore, USA
email: [email protected]
Prof. Tapan K. Sengupta
High Performance Computing Lab,
Department of Aerospace Engineering,
Indian Institute of Technology,
Kanpur, India
email: [email protected]
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