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Nervous System Lesson 1: Structure of the Nervous System Module Introduction Module Introduction Lesson 1: Structure of the Nervous System Lesson 2: Organization of the Nervous System Lesson 3: The Senses Lesson 4: Effects of Drugs Module Wrap-Up Learning Objectives By the end of this lesson, you should be able to: 1. Describe the structure of a neuron 2. Explain the function of each part of a neuron 3. Analyze How does a nerve impulse move along a neuron Discussion Question If you step on several toy blocks, it’s going to hurt. Why is this response a good thing? Key Vocabulary • • • • • • Spinal Cord الحبل الشوكي Neuron خلية عصبية Dendrite التغصنات Axon محور عصبي Cell body جسم الخلية Reflex arc قوس انعكاسي • Review: • Diffusion Describe the structure of a neuron Nervous System A communication network that extends throughout your body. Nervous system is made of : 1. Spinal cord 2. Brain 3. Nerve cells (Neurons) Describe the structure of a neuron Let’s have a look at the neuron structure by watching this video! Describe the structure of a neuron Neurons Neurons are specialized nerve cells: help you gather information about your environment interpret the information and react to it. Neurons consist of three main regions: Dendrites Cell body Axon Describe the structure of a neuron Dendrites pass signals they receive on to the cell body in electrical impulses. The axon passes those impulses on to the other neurons or muscles. Synapse: A small gap between axon of one neuron and dendrite of another neuron Describe the structure of a neuron Look at both neurons, what can you see different between them? This is called the Myelin sheath The Myelin sheath is made up of protein and fatty substances. It allows electrical impulses to transmit quickly and efficiently along the nerve cells. Explain the function of each part of a neuron Types of Neurons Watch this video and then write the three types of neurons in the chat box https://teachers.boclips.co m/videos/5c54da71d8eafee cae225f23?referer=92403e0 0-a083-40dd-8372655757595907 CODE 40jq Time: 3 minutes Explain the function of each part of a neuron Nervous System Types of Neurons 1. Sensory neurons send impulses from receptors in the skin and sense organs to the brain and spinal cord. 2. Interneurons carry impulses to motor organs (found in the spinal cord and brain). 3. Motor neurons carry impulses away from the brain and spinal cord to a gland or muscles, resulting in a secretion/movement Explain the function of each part of a neuron Think with me! • How do you respond when you touch a hot object? Move away from or drop the object. Many reflexes are fast so that they occur before the brain can interpret the situation. • What would happen if you had to wait for the brain to interpret the stimulus and signal an appropriate response? In this short amount of time, a severe burn could occur. Explain the function of each part of a neuron Reflex Arc: a nerve pathway of sensory neuron interneuron motor neuron Brain is NOT involved Spinal cord is involved Fast response involuntary Explain the function of each part of a neuron Explain the function of each part of a neuron The impulse reaches the spinal cord, which sends an impulse to motor neurons in response. Assessment Plenary Let’s play Quizizz! https://quizizz.com/admin/quiz/61d3332e0d3278001d4f378a/neuron-structure Learning Objectives • By the end of this section, you should be able to: 1. Define the stimuli and nerve impulses 2. Explain How does a nerve impulse move along a neuron 3. Analyze the nerve impulse using a simulation. Starter Let’s label the parts of the neuron: https://wordwall.net/resource/20348976/neuron Define the stimuli and nerve impulses Recall We learned about neuron structure in the last class. Can you guess how a signal can travel through it? Define the stimuli and nerve impulses 1. Stimulus A stimulus is any change in our surroundings that can cause a response. How do we respond to a stimulus? A stimulus is created. Our receptors detect this stimulus. Receptors create nerve impulse in our body. Nerve impulse makes our body respond. Define the stimuli and nerve impulses Nerve Impulse • Electrical charge (signal) that travels along the neuron • A nerve impulse results from a stimulus Another name for nerve impulse is ACTION POTENTIAL Define the stimuli and nerve impulses A Nerve Impulse: a Neuron at rest Neurons at rest do not conduct impulses. Na+ outside more K+ Inside more Define the stimuli and nerve impulses Action Potential This is an electric signal that travels along a neuron. Nerve impulse is also called Action Potential. How is this electrical signal created? It is because of charged ions moving in and out of the axon. Explain How does a nerve impulse move along a neuron Nervous System Neuron at rest Sodium ions (Na+) collect on the outside of the cell membrane. Potassium ions (K+) collect on the inside of the cell membrane. Negative charged proteins actively transport sodium ions out of the cell and potassium ions into the cell. Explain How does a nerve impulse move along a neuron Action Potential (nerve impulse) Explain How does a nerve impulse move along a neuron Neuron’s internal environment What is happening inside a neuron? Let's have a look. The internal environment is controlled by three factors: 1. Sodium (Na+) and Potassium (K+) ions 2. Sodium and Potassium Ion channels 3. Sodium/Potassium Pumps Explain How does a nerve impulse move along a neuron 1. Sodium (Na+) and Potassium (K+) ions 2. Sodium and Potassium Ion channels 3. Sodium/Potassium Pumps • They are positively charges • Present more outside than inside the axon • They are like door on the axon cell membrane that allow the sodium and potassium ions to pass through (passive) • They are pumps that transport 3 Sodium for every 2 potassium ions (active) Let’s visualize the action potential using this simulation: Explain How does a nerve impulse move along a neuron Threshold Sometimes you don’t feel an insect land on you. Can you guess why? The minimum stimulus to cause an action potential is called a threshold. Action potential are described as “ALL or NOTHING” Explain How does a nerve impulse move along a neuron Threshold If a stimulus is not strong enough, no response is created. Only if the stimulus is strong enough it can create an action potential in the neuron. This is called the threshold stimulus. Less than threshold = No response Higher than threshold = response Nervous System Action Potential (nerve impulse) 1. The stimulus causes sodium channels in the neuron's membrane to open (Na+ ions from outside the membrane enter the cell) The cell's interior becomes more positive. 2. Sodium channels close and potassium channels open (K+ ions from inside the membrane move outside the cell) The cell's exterior restores the positive charge. The signal passes down the length of the axon like a wave. Activity • Go to this link: https://www.liveworkshee ts.com/c?a=c&sr=n&ms=u z&l=ib&i=unznuzt&r=pb& db=0&f=dzddzuzf&cd=klof xlglxgzhf2ngnngxgexg • You have 3 minutes to finish the activity Plenary • Go to your LMS. • Answer the POLL question there • You have 2 minutes to answer. Learning Objectives By the end of this lesson, you should be able to: Analyze How does a nerve impulse move along a neuron Starter discussion You miss your friends from school. How do you stay in contact? How does that communication happen? LMS • Go to your LMS. • Answer the POLL question there • You have 2 minutes to answer. Key Vocabulary • Node عقدة • Synapse مشبك عصبي • Neurotransmitterناقل عصبي • Myelin Sheath غمد مايليني • Review: • Diffusion Analyze How does a nerve impulse move along a neuron Nervous System Speed of an Action Potential Myelin Sheath In certain neurons, the axon is surrounded by an insulating lipid covering called myelin sheath. Analyze How does a nerve impulse move along a neuron Nervous System Speed of an Action Potential Nodes along the axon allow ions to pass through the myelin layer to the plasma membrane. The ions jump from node to node and increase the speed of the impulse. Analyze How does a nerve impulse move along a neuron Think with me! Knowing that the action potential in the neurons with Myelin sheath is faster than the neurons without Myelin sheath when a myelin sheath is useful and when is it not needed? Neurons with Myelin Carry impulses that are associated with sharp pain Neurons without Myelin Carry impulses that are associated with dull pain Analyze How does a nerve impulse move along a neuron How Neurons Communicate? Let’s watch the video! Analyze How does a nerve impulse move along a neuron Nervous System The Synapse The small gap between the axon of one neuron and the dendrite of another neuron is called a synapse. An action potential is carried across these gaps by neurotransmitters. Neurotransmitters are chemicals that bind to the receptors Example: Acetylcholine (Ach) Analyze How does a nerve impulse move along a neuron Neurotransmitter 1 Vesicles near to end of the axon terminal store neurotransmitters. 2 A nerve impulse causes the vesicle to merge with the cell membrane. It then releases the neurotransmitters into the synapse through exocytosis. 3 4 The neurotransmitter binds to receptors at the end of the dendrites of the next neuron. The binding of the neurotransmitter causes the dendrites to generate a nerve impulse that travels to the cell body. Activity • Go to this link: https://www.liveworkshee ts.com/c?a=c&sr=n&ms=u z&l=fz&i=dsxndns&r=ip&d b=0&f=dzddzuzf&cd=klegn pmlnlpoh2ngnngxgexg You have 2 minutes to finish the activity Analyze How does a nerve impulse move along a neuron Think with me!! • Once the neurotransmitters have done their work, do you think they need to be kept in the synapse? Analyze How does a nerve impulse move along a neuron Neurotransmitter • Once the neurotransmitters have done their work, they are either: 1. destroyed enzymatically, 2. taken back into the terminal from which it came 3. recycled and reused. Let’s play Kahoot! https://create.kahoot.it/details/a1784810-bc52-4c4c-96876bac5f08a1da Nervous System Chapter Diagnostic Questions Another name for a nerve impulse is _______. A. synapse B. threshold C. reflex arc D. action potential 1. 2. 3. 4. A B C D CDQ 2 Nervous System Section 1 Formative Questions What type of neuron begins a reflex arc? A. interneuron B. motor neuron C. sensory neuron D. transmitter neuron 1. 2. 3. 4. A B C D Nervous System Section 1 Formative Questions A stronger stimulus will cause a stronger action potential. A. True B. False 1. 2. A B FQ 3 Nervous System Section 1 Formative Questions When a neuron is at rest, what maintains the high concentration gradients of potassium ions inside the cell and sodium ions outside the cell? A. B. C. D. diffusion osmosis active transport ion channels 1. 2. 3. 4. A B C D FQ 4 Develop Concepts Scaffolding • ASK STUDENTS: Describe the distribution of ions inside and outside of a resting neuron. There are more sodium ions outside the neuron and more potassium ions inside the neuron. The distribution of these ions is unequal. There are more negative ions in the cytoplasm than there are outside the cell. So, the inside of the neuron is negatively charged in relation to the outside of the neuron. • ASK STUDENTS: • Explain the reversal of electrical charges that occurs as an action potential travels along the neuron. An action potential results in the opening of channels in the plasma membrane. Positively charged sodium ions rush into the cytoplasm, causing a reversal of charges. • Analyze what would be the effect if the sodium/potassium pump carried equal numbers of sodium and potassium ions across the plasma membrane. There would not be much of a difference in electrical charges inside and outside the neuron. • Develop a mechanism that would prevent an action potential from traveling along the neuron. Accept any mechanism that prevents the influx of sodium ions; some drugs bind to specific receptors on the dendrites, blocking a substance that could trigger an action potential.