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DISEASES OF CHEST WALL By Yashdeep, 7 th Sem 4 th Group If Diagnosis is clear during CT or MRI scan Benign Fibrous Tumours dysplasia Chondroma Osteochondroma Lipoma Rhabdomyosarcoma Malignant Tumors Chondrosarcoma If Diagnosis is NOT clear during CT or MRI scan Malignant soft tissue sarcoma Fibrosarcoma Malignant fibrous histiocytoma Liposarcoma Angiosarcomas Ewing’s sarcoma Osteosarcoma Benign Tumours Osteochondroma An overgrowth of cartilage and bone Happens at the end of the bone near the growth plate Common in males Cause pain as they progress Symptoms can show A hard, mass that is painless Lower-than-normal-height for age Soreness of the nearby muscles Diagnosed by X-Ray, CT, MRI Surgical treatment is resection Chondroma Rare, slow-growing tumour Made up of cartilage and forms on or in bones or soft tissue Primarily seen in children's and young adults Painless mass is present Most chondromas do not cause symptoms, but pain, swelling, and broken bones can occur Treatment is surgical resection with a 2cm margin Fibrous dysplasia Frequently occurs in young adults A chronic problem in which scar-like tissue grows in place of normal bone Excision is recommended to reduce symptoms Lipoma Benign tumour composed of adipose tissue fatty tumor located just below the skin Onset is 40-60 yrs Lipomas tend to run in families. Risk factor incluse obesity, family history, insufficient exercise Malignant Tumors Chondrosarcoma A type of bone cancer that develops in cartilage cells Slowly enlarge and can reach massive size Are painful Risk factors can be • Increasing age - most often in middle-aged and older adults, • Other bone diseases Diagnosed by physical exam, X-Ray, CT, MRI, Biopsy Should be treated with 4cm wide complete resection Ewing’s sarcoma Occurs in bones or in the soft tissue around the bones Ewing sarcoma most often begins in the leg bones and in the pelvis More common in children and teenagers Symptoms can include: • Pain, swelling or tenderness near the affected area • Unexplained tiredness • Fever with no known cause • Losing weight without trying the DNA changes most often affect a gene called EWSR1 Osteosarcoma Usually develops in the osteoblast cells that form bone Present as rapidly enlarging painful masses Tends to occur in teenagers and young adults Symptoms: • Swelling near a bone • Bone or joint pain • Bone injury or bone break for no clear reason Treatment usually involves chemotherapy, surgery and, sometimes, radiation therapy Malignant soft tissue sarcoma Include Fibrosarcoma Malignant fibrous histiocytoma Liposarcoma Angiosarcomas Rhabdomyosarcoma Angiosarcomas They are uncommon Primary treatment is wide surgical resection with 4cm margins and reconstruction except Rhabdomyosarcoma. Rhabdomyosarcoma are treated with chemo. Prognosis depends on their grade and stage Malignant fibrous histiocytoma Liposarcoma Fibrosarcoma Rhabdomyosarcoma