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Molecular 5
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Points: 8/8
1. Which of the following is true about DNA polymerase?
(1/1 Points)
It can synthesize DNA in the 5’ to 3’ direction
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It can synthesize DNA in the 3’ to 5’ direction
It can synthesize mRNA in the 3’ to 5’ direction
It can synthesize mRNA in the 5’ to 3’ direction
2. What is the reaction in DNA replication catalyzed by DNA ligase?
(1/1 Points)
Addition of new nucleotides to the leading strand
Addition of new nucleotide to the lagging strand
Formation of a phosphodiester bond between the 3’-OH of one Okazaki
fragment and the 5’-phosphate of the next on the lagging strand
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Base pairing of the template and the newly formed DNA strand
3. Which of the following enzymes remove supercoiling in replicating DNA ahead of
the replication fork?
(1/1 Points)
DNA polymerases
Helicases
Primases
Topoisomerases
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4. Which enzyme used to join bits of DNA?
(1/1 Points)
DNA polymerase
DNA ligase
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Endonuclease
Primase
5. Name the protein, which is responsible for the formation of RNA primer?
(1/1 Points)
Topoisomerase
Gyrase
Helicase
Primase
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6. What is the role of topoisomerases in eukaryotic DNA replication?
(1/1 Points)
Topoisomerise enzymes cut, uncoil and reseal the double stranded DNA
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Topoisomerise enzymes bind to the origin of replication sites within double
stranded DNA
Topoisomerise enzymes open up the double stranded DNA at the
replication fork
Topoisomerise enzymes open up the double stranded DNA at the
replication fork
7. What is the function of enzyme involved in base excision repair?
(1/1 Points)
Addition of correct base
Addition of correct nucleotide
Removal of incorrect base
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Removal of phosphodiester bond
8. An apyrimidinic or apurinic (AP) site forms in which type of DNA repair?
(1/1 Points)
Base excision repair
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Photoreactivation
Mismatch repair
Nucleotide excision repair
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