Survey
* Your assessment is very important for improving the workof artificial intelligence, which forms the content of this project
* Your assessment is very important for improving the workof artificial intelligence, which forms the content of this project
Annex 3A: Technology Offer Template TECH OFFER FORMAT Headings Examples 1. Category [See Technology Themes to choose the category of the invention/technology] 2. Title In non-technical terminology as far as possible GranuMaS®: Synthetic Human Bone Graft 3. Abstract / Summary [Limit to 255 characters] A brief summary or description of the invention - What is the problem solved by this technology? Who is going to buy this technology? How is this IP addressing a need/problem in the marketplace? Bone grafting is a common procedure in surgical operations for Orthopaedics, Trauma, ENT, Dental, Plastics and Maxillofacial. The gold standard in using bone from the patient itself is limited due to the limited quantity of bone grafts available for harvesting from a patient. Also major concern on transmission of infections and diseases particularly Hepatitis B and C, and HIV are associated with bone from other human donor. Therefore, the most promising material for skeletal repair is the synthetic material. GranuMaS® is a granular synthetic bone graft material made from Hydroxyapatite, which is similar to human bone mineral. Since its first clinical applications in 2004, thousands of orthopaedics and dental patients have benefited by using GranuMaS®. Clinical results shows very encouraging performance of GranuMaS® - such as no adverse reactions, no evidence of inflammation reaction, good healing process, no infection and no complain of pain. Therefore, GranuMaS® is a great alternative material for use as bone graft in surgical applications. 4. Technology Features & Specifications [100-150 words] What does the technology comprise of? GranuMaS® - an “osteoconductive” material - comes in various sizes and shapes such as Granule,Cube,Chip and pin. The sizes of GranuMaS® produced are 200 – 500 m, 500 – 1000 m, 1000 – 2500 m and 2500 – 5000 m. The spherical GranuMaS® shapes enable the material to be poured and to be packed into a bone cavity easily. The different sizes will suit different surgical sites and applications. 5. Potential Applications [100-300 words] In which industry can this technology be employed? What are the products that can be marketed based on this technology? Annex 3A: Technology Offer Template GranuMaS® - as “osteoconductive” material - can be used directly in surgical operations for Orthopaedics, Trauma, ENT, Dental, Plastics and Maxillofacial that requiring bone grafting material. It is used as bone filler to fill in the bony cavity created either by trauma – e.g. motor vehicle accidents, or diseases – e.g. osteoporosis and bone cancer. For large bone cavity such as bone cancer, GranuMaS® can either be mixed with bone marrow aspirate, growth hormone and/or platelet-rich plasma to increase its “osteoinductive” property. Alternatively, it can also be used as filler in PMMA bone cement during metallic hip or knee implantation. The spherical shape of GranuMaS® is also ideal as a plasmasprayed raw material to produce hydroxyapatite-coated metallic implants for Orthopaedics applications. GranuMaS® can also be used as one of the ingredient in dental tooth paste to reduce teeth-sensitivity and to improve its whiteness. 6. Customer Benefits [100-300 words] How is this improvement over the "State of the Art?" What is the Value Proposition? GranuMaS® is a great alternative material for use as bone graft in surgical applications. It is derived from commercial chemicals and Malaysian limestone, thus its medical grade quality and purity is continuously consistent and readily available in large quantity at competitive prices. GranuMaS® is FREE from any animal-derived products (e.g. cattle or pig origin), thus obviate the concerns of cross-transmission of diseases between animal to human, adverse immune response, ethical and religious issues. [100-200 words] 7. Market Trends and Opportunities What is the approximate market size for this technology? What makes this IP attractive to the market? The global market for orthopedic bone graft substitutes is expected to reach US$3.4 billion and the global dental bone graft market US$1 billion (reportlinker.com) by 2017. Dental bone graft alone is estimated to expand at a CAGR of 10.6% over the period from 2014 to 2020 (transparencymarket research.com). [100-200 words] 8. Graphic File 2480 x 1748 pixels Annex 3A: Technology Offer Template [In CMYK format, with min 300dpi]