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CHAPTER 11 Anatomy and Physiology of the Human Body UNIT 1 Anatomical Descriptors and Fundamental Body Structure 11 - 2 Copyright © 2008 Thomson Delmar Learning, a division of Thomson Learning Inc. All rights reserved. Anatomical Position A body is said to be in the anatomical position when the patient is standing erect, with the arms down at the sides, and the palms of the hands facing forward. 11 - 3 Copyright © 2008 Thomson Delmar Learning, a division of Thomson Learning Inc. All rights reserved. Appropriate Terminology for Anatomical Directions 11 - 4 To describe exact location when charting, the body is divided by imaginary lines. One line divides the body into right and left. The other line divides the body into upper and lower halves. (continued) Copyright © 2008 Thomson Delmar Learning, a division of Thomson Learning Inc. All rights reserved. Appropriate Terminology for Anatomical Directions Medial Proximal Farthest from the point of attachment Lateral 11 - 5 Nearest the point of attachment Distal Toward the midline Away from the midline (continued) Copyright © 2008 Thomson Delmar Learning, a division of Thomson Learning Inc. All rights reserved. Appropriate Terminology for Anatomical Directions Anterior Cranial Toward the front Toward the front or belly side Superior Above the transverse plane Below the transverse plane Caudal Toward the head Inferior Ventral Toward the front Frontal Toward the tail or feet Posterior Toward the back 11 - 6 Copyright © 2008 Thomson Delmar Learning, a division of Thomson Learning Inc. All rights reserved. Body Cavities and Major Organs The body is divided into two main cavities: 1. Anterior or ventral 2. Cavity toward the belly side that contains the head, chest, and major abdominal organs Posterior or dorsal Cavity toward the back that contains the brain and spinal cord 11 - 7 Copyright © 2008 Thomson Delmar Learning, a division of Thomson Learning Inc. All rights reserved. The Diaphragm Diaphragm A large dome-shaped muscle that separates the thoracic cavity from the abdominal cavity 11 - 8 Copyright © 2008 Thomson Delmar Learning, a division of Thomson Learning Inc. All rights reserved. The Organs of the Abdomen The abdomen contains the: Stomach Small intestine Most of the large intestine Liver Spleen Pancreas Gallbladder 11 - 9 Copyright © 2008 Thomson Delmar Learning, a division of Thomson Learning Inc. All rights reserved. The Regions of the Abdomen 11 - 10 Because of its size, the abdomen is first divided into four areas called quadrants. (continued) Copyright © 2008 Thomson Delmar Learning, a division of Thomson Learning Inc. All rights reserved. The Regions of the Abdomen The abdomen is then divided into 9 regions for purposes of identification and reference. 11 - 11 Copyright © 2008 Thomson Delmar Learning, a division of Thomson Learning Inc. All rights reserved. The Basic Characteristics of a Cell The cell is the basic building block of the human body: 11 - 12 Cells need nutrients and oxygen to survive. Cells perform specific functions. Cells produce heat and energy. Cells can give off waste products. Some cells can reproduce themselves. (continued) Copyright © 2008 Thomson Delmar Learning, a division of Thomson Learning Inc. All rights reserved. The Basic Characteristics of a Cell Organelles are minute bodies within the cytoplasm: 11 - 13 Nucleus Mitochondria Ribosomes Centriole Endoplasmic reticulum Golgi apparatus Lysosomes Some organelles physically separate the chemical reactions that are not compatible. Organelles also control the time when reactions take place. (continued) Copyright © 2008 Thomson Delmar Learning, a division of Thomson Learning Inc. All rights reserved. The Basic Characteristics of a Cell Chromosomes Located within the nucleus, each human has 23 pairs of chromosomes that store the hereditary material passed from one generation to the next 22 pairs are identical. The 23rd pair are the sex chromosomes: 11 - 14 XY = male XX = female (continued) Copyright © 2008 Thomson Delmar Learning, a division of Thomson Learning Inc. All rights reserved. The Basic Characteristics of a Cell Cytoplasm Cell membrane Fluid that makes up the cell Separates the cell from the surrounding environment Cytoplasm Semisolid fluid within the membrane where chemical reactions, such as respiration, occur 11 - 15 Copyright © 2008 Thomson Delmar Learning, a division of Thomson Learning Inc. All rights reserved. What Happens When Mutations Occur DNA that is lost, rearranged, or paired in error results in a change in the genetic code called a mutation. 11 - 16 Copyright © 2008 Thomson Delmar Learning, a division of Thomson Learning Inc. All rights reserved. Six Ways Molecules Pass Through Cell Membranes 1. Diffusion 2. Osmosis 11 - 17 Gas, solids, or liquids are distributed evenly through a medium. Diffusion of water or another solvent through a selectively permeable membrane (continued) Copyright © 2008 Thomson Delmar Learning, a division of Thomson Learning Inc. All rights reserved. Six Ways Molecules Pass Through Cell Membranes 3. Filtration 4. Active transport 11 - 18 Movement of solutes and water across a semipermeable membrane Filtration occurs as a result of force such as gravity or blood pressure. Molecules move across a membrane from an area of low concentration to an area of high concentration. (continued) Copyright © 2008 Thomson Delmar Learning, a division of Thomson Learning Inc. All rights reserved. Six Ways Molecules Pass Through Cell Membranes 5. Phagocytosis 6. White blood cells become phagocytes and engulf bacteria, cell fragments, or damaged cells. Pinocytosis Cells engulf large molecules of liquid materials; cell drinking 11 - 19 Copyright © 2008 Thomson Delmar Learning, a division of Thomson Learning Inc. All rights reserved. The Patterns of Inheritance and How They Affect a Trait A trait is a recognizable result of the effect of a gene or a group of genes 3 patterns of inheritance can produce these traits 1. 2. 3. Dominant genes: produce the trait Recessive genes: produce the trait if both parents have the same mutation X-linked: traits that are sex linked 11 - 20 Copyright © 2008 Thomson Delmar Learning, a division of Thomson Learning Inc. All rights reserved. Genetic and Congenital Disorders These disorders can result from improper sex cell division at the time of fertilization, from the inheritance of altered genes, or as the result of environmental factors or poisons. 11 - 21 Copyright © 2008 Thomson Delmar Learning, a division of Thomson Learning Inc. All rights reserved. Cleft Lip and Cleft Palate Cleft lip A structural defect is present in the upper lip caused by failure of the soft or bony tissues to unite during the 8th to 12th week of gestation. Cleft palate A structural defect is present in the roof of the mouth caused by failure of the soft or bony tissues to unite during the 8th to 12th week of gestation. 11 - 22 Copyright © 2008 Thomson Delmar Learning, a division of Thomson Learning Inc. All rights reserved. Down Syndrome A genetic syndrome caused by improper cell division Occurs in about 1 in every 1,000 births, depending on the mother’s age The result is an extra chromosome 21. Down syndrome has several physical characteristics, e.g., slanting eyes, large tongue, pug nose, and a small head. Mental retardation occurs in all cases and there is some degree of growth restriction. 11 - 23 Copyright © 2008 Thomson Delmar Learning, a division of Thomson Learning Inc. All rights reserved. Spina Bifida A structural malformation of the spine The posterior portion of the spinal tissues fails to close during the first 3 months of pregnancy. 11 - 24 Copyright © 2008 Thomson Delmar Learning, a division of Thomson Learning Inc. All rights reserved. Klinefelter’s Syndrome Sex-linked disorder where there is one or more extra X chromosomes; affects 1 in every 600 males. At puberty, the penis and testicles fail to mature and there is little body hair. Breasts may enlarge and long legs with a short, obese trunk are noted. 11 - 25 Copyright © 2008 Thomson Delmar Learning, a division of Thomson Learning Inc. All rights reserved. Talipes A structural deformity of one or both feet Commonly called clubfoot There may be varying degrees of inward, outward, downward, or upward turning of one or both feet. 11 - 26 Copyright © 2008 Thomson Delmar Learning, a division of Thomson Learning Inc. All rights reserved. Turner’s Syndrome Sex-linked defect that affects about 1 in every 10,000 females. Only 45 chromosomes are present because the sex cells failed to divide correctly. Ovaries fail to develop. The chest is wide and there is poor breast development and underdevelopment of the genitalia. 11 - 27 Copyright © 2008 Thomson Delmar Learning, a division of Thomson Learning Inc. All rights reserved. Discoveries in Genetics February 2001: The Human Genome Project identified a 3 billion letter code of human DNA, which is the chemical sequence containing the basic information for building and running a human body. This sequence determines every human characteristic from eye color to vulnerability to disease. 11 - 28 Copyright © 2008 Thomson Delmar Learning, a division of Thomson Learning Inc. All rights reserved. DNA Fingerprinting This method of identification can match blood, semen, and body fluids found at crime scenes to the DNA of the criminal. Evidence of a DNA match is considered to be a positive identification. 11 - 29 Copyright © 2008 Thomson Delmar Learning, a division of Thomson Learning Inc. All rights reserved. Cell to Tissue Progression When cells of the same type group together for a common purpose, they form a tissue. Tissue has four main classifications and is 60% to 99% water. 11 - 30 Copyright © 2008 Thomson Delmar Learning, a division of Thomson Learning Inc. All rights reserved. Four Main Types of Body Tissue 1. Epithelial tissue 2. Connective tissue 11 - 31 Forms the body’s glands, covers the surface of the body, and lines the body cavities Connects tissues together to form the organs and body parts (continued) Copyright © 2008 Thomson Delmar Learning, a division of Thomson Learning Inc. All rights reserved. Four Main Types of Body Tissue 3. Nerve tissue 11 - 32 The basic structural unit of this tissue is the neuron, which serves as the body’s communication network. These neurons are made up of a nerve cell body and fibers that resemble tree branches to bring impulses toward the cell and carry impulses away from the cell. (continued) Copyright © 2008 Thomson Delmar Learning, a division of Thomson Learning Inc. All rights reserved. Four Main Types of Body Tissue 11 - 33 Sensory neurons in the skin or sensory organs send impulses to the brain and spinal cord. Interneurons carry impulses to another neuron. Motor neurons receive an impulse and send a message, which causes a reaction. (continued) Copyright © 2008 Thomson Delmar Learning, a division of Thomson Learning Inc. All rights reserved. Four Main Types of Body Tissue 4. Muscle tissue Designed to contract on stimulation Involuntary action occurs without control or conscious awareness, such as the heartbeat and respirations. Tissues controlled at will by brain impulses are called voluntary muscle tissue. 11 - 34 Copyright © 2008 Thomson Delmar Learning, a division of Thomson Learning Inc. All rights reserved. Body Organs The organs are made up of two or more types of tissues working together to perform a specific body function. The human body is made up of 10 body systems and the organs of each are discussed in the unit that relates to that particular body system. 11 - 35 Copyright © 2008 Thomson Delmar Learning, a division of Thomson Learning Inc. All rights reserved. The 10 Body Systems 1. Integumentary 2. Muscular system 3. 11 - 36 Bones and joints Nervous system 5. Muscles Skeletal system 4. Skin Brain and spine Endocrine system 9 glands (continued) Copyright © 2008 Thomson Delmar Learning, a division of Thomson Learning Inc. All rights reserved. The 10 Body Systems Circulatory system 6. Respiratory system 7. Mouth, nose, and lungs Digestive system 8. Intestines Urinary system 9. Bladder, kidneys, ureters, and urethra Reproductive 10. 11 - 37 Heart and blood vessels Sex organs Copyright © 2008 Thomson Delmar Learning, a division of Thomson Learning Inc. All rights reserved. Unit Summary Name the main types of tissue. What causes a cleft lip and cleft palate? What causes Down syndrome? 11 - 38 Copyright © 2008 Thomson Delmar Learning, a division of Thomson Learning Inc. All rights reserved.