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Diabetes in Pregnancy N323: Parent-Child Nursing S. Burke, PhD, RN, CDE Pre-Gestational Diabetes Mother/Baby Risks Pre-existing Diabetes, either type 1 or type 2 Definition & Diagnosti c Criteria Diabetes diagnosed during pregnancy Gestational Diabetes Mother/Baby Risks Pre-conception counseling Diabetes in Pregnancy At Risk Populations: Testing: Management: Management: Testing: A Little Background Prevalence of diabetes is increasing at a rapid rate As of 2006 20.8 million Americans with Diabetes 90% Type 2 ~ 1/3 undiagnosed ~ 16% children and teens w/T2DM http://www.med.umich.edu/intmed/endocrinology/images/t2_1_1.gif Definitions Pre-gestational diabetes Gestational Diabetes (GDM) Diabetes that is present prior to a pregnancy Type 1 or Type 2 Carbohydrate intolerance of variable severity with the onset or first recognition during pregnancy AADE Core Curriculum 4th ed., (2001), p. 34 Prevanlence of Obesity, Diabetes and other obesity related risk factors http://www.cdc.gov/diabetes/statistics/maps/slide95.gif High Risk Populations Low Risk Women Medium Risk Women High Risk Women < age 25 BMI > 25 BMI 19 – 25 Neither high nor low risk +FHx of T2 DM Low risk + glucosuria ethnicity Negative FH Negative personal history No h/o poor OB outcomes Hx/O GDM Hx/O baby w/bw over 9# Member of high risk ethnic group Maternal Risks Pre-existing DM Type 1 DM Type 2 DM Ketoacidosis Frequent hypoglycemia Obesity Hypertension Both Worsening Kidney disease Eye disease Coronary heart disease GDM Hypertensive disorders PIH Toxemia Development of Type 2 diabetes following IUP Fetal/Newborn Risks Pre-gestational DM Early Risks Birth Defects Spontaneous AB Later Risks Hyperinsulinemia Overgrowth Stillbirth Polycythemia RDS Intrauterine growth retardation (a/w nephropathy) GDM Hyperinsulinemia Macrosomia (>4,000 G) Possibility of stillbirth Newborn Risks Difficult birth Shoulder Dystocia Neonatal hypoglycemia hyperbilirubinemia 2 Step Testing (GDM) Step 1 = 1 hour test 50 Gram Glucose Load followed by plasma glucose at 1 hour if > 140 mg/dL, go to Step 2 Step 2 = 3 hour test 100 Gram Glucose Load Diagnostic Criteria 100 Gram Glucose Load Fasting Plasma Plasma Glucose Levels Glucose Levels 105 mg/dL 95 mg/dL 1 hour 190 mg/dL 180 mg/dL 2 hour 165 mg/dL 155 mg/dL 3 hour 145 mg/dL 140 mg/dL Treatment Meal Planning All patients Exercise Physical Activity that does not fetal risk Blood Glucose Monitoring All patients Insulin All pre-gestational Some GDM http://www.cfpc.ca/cfp/2005/May/headimage.jpg Glycemic Goals During Pregnancy Fasting Glucose Less than or equal to 105 mg/dL Pre-meal Glucose Less than or equal to 105 mg/dL 1 hour after eating Less than or equal to 155 mg/dL 2 hours after eating Less than or equal to 130 mg/dL Insulin Preparation Onset Peak Duration Rapid 5 – 15 min. 90 min. 4 - 6 hours Regular 30 min. 2 – 4 hrs 6 - 8 hours Intermediate (NPH) ~ 2 hours 4 – 10 hrs 12 – 20 hrs Long acting ~ 4 hours Flat peak Up to 24 hrs http://z.about.com/f/p/440/diabetes2/d/i/Gest_Diabetes.jpg http://www.cumc.columbia.edu/news/frontiers/images/biof040216.gif Meal Planning Diet should be Individualized Culturally appropriate Nutritional Goals Provide sufficient calories for normal fetal growth and development Avoid hyperglycemia General Nutritional Guidelines Spread carbohydrates throughout the day 3 meals, 3 small snacks Fewer carbs during periods of higher insulin resistance, e.g., AM hours Avoid high glycemic index foods Sugary foods or fluids between meals Use of sugar substitutes is OK Exercise is important Exercises reduces insulin resistance Walking is generally well tolerated, cheap, and easy. AM time frame is when insulin resistance is greatest, but… consistent exercise has a lasting impact. Goal: patient directed, provider approved, consistent activity at least every other day. Monitoring for Ketones