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Chapter 20 Sexually Transmitted Diseases 1-1 Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. Chlamydia • Chlamydia trachomatis is a bacterium that is spread by sexual contact and infects the genital organs of males and females • One of the major sexually transmitted diseases • Nongonococcal urethritis - refers to chlamydia infection in males 1-2 Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. Symptoms • Male: thin, clear discharge and mild discomfort on urination • Women: asymptomatic • Treatment - curable with azithromycin or doxycycline • Prevention - screening, consistent use of a condom 1-3 Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. HPV • Human papilloma virus - causes genital warts • Diagnosis - inspection of the warts, analysis of DNA • Treatment - podophyllin acid, cryotherapy, laser therapy • Vaccine - currently being tested 1-4 Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. Genital Herpes • A disease of the genital organs caused by the herpes simplex virus Type II • Symptoms - small, painful bumps or blisters on the genitals on vaginal lips on females and penis on males • 45 million Americans (22%) are infected • Treatment - no cure; drug acyclovir prevents or reduces symptoms 1-5 Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. Long-Term Consequences • Complications such as meningitis or narrowing of the urethra, increases risk of becoming infected with HIV, risk of transferring virus from mother to infant in childbirth • Psychological aspects - help patients learn to cope with disease 1-6 Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. HIV Infection and AIDS • AIDS - acquired immune deficiency syndrome • HIV - human immune deficiency virus; the virus that causes AIDS 1-7 Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. HIV Infection and AIDS • An epidemic? Dec. 1997 more than 640,000 persons in the U.S. have been diagnosed with AIDS • Transmission - exchange of body fluids, contaminated blood, contaminated needles, infected woman to baby during pregnancy or childbirth 1-8 Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. The Virus • HIV is one of a group of retroviruses • The disease - 4 classes of HIV infection: – – – – Initial infection Asymptomatic carrier state Lymphadenopathy - symptoms develop AIDS • Diagnosis - ELISA, Western blot or immunoblot method 1-9 Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. Treatment • • • • • 1-10 No cure for AIDS AZT - antiviral drug DDI Protease inhibitors Pentamidine Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. Women, Children, Ethnic Minorities, and AIDS • About 90% of the cases of AIDS in the U.S. have been men • Number of infected women is rising rapidly • 9.2 million women worldwide are infected with HIV • Psychological considerations in AIDS - need for sensitivity • Recent progress in AIDS research - work on vaccine, research on nonprogressors, Chemokines 1-11 Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. Gonorrhea • Also called clap or drip; caused by a bacterium • Symptoms - puslike discharge and painful, burning urination in male but asymptomatic in female • Diagnosis - sample of discharge is examined • Treatment - antibiotic such as ceftriaxon 1-12 Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. Syphilis • Caused by a bacterium • Symptoms - chancre • Stages: – – – – 1-13 Primary Secondary Latent Late Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. Diagnosis • Physical exam, exam fluid from chancre • Blood tests - VDRL; Venereal Disease Research Laboratory of the U.S. Public Health Service • Treatment - penicillin • Elimination of syphilis? Not eliminated as of yet 1-14 Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. Viral Hepatitis • A disease of the liver • Symptom - enlarged liver that is somewhat tender • 5 types of viral hepatitis: hepatitis A, B, C, D, and E • Treatment - rest, vaccine for hepatitis B 1-15 Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. Pubic Lice • Also called crabs • Tiny lice that attach to the base of pubic hairs and feed on blood from their human host • Symptom - itching • Treatment - lindane 1-16 Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. Preventing STDs • Limit oneself to monogamous relationships • Condoms can help • Careful washing 1-17 Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. Other Genital Infections • • • • • Vaginitis - vaginal inflammation Monilia - yeast infection Trichomoniasis Nonspecific vaginitis Cystitis - infection of the urinary bladder in women • Prostatitis - inflammation of the prostate gland 1-18 Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display.