Download European Journal of Clinical Pharmacology Volume 64 • Number 9

European Journal
of Clinical Pharmacology
Volume 64 • Number 9 • September 2008
OBiTUARY
PHARMACOKINETICS AND DISPOSITION
Professor Dr. Nina Bakracheva
RA. Thiirmann ■ E. Gatchev • U. Fuhr • S. Harder 835
Plasma esterases and inflammation in ageing and frailty
RE. Hubbard ■ M.S. O'Mahony ■ B.L Calver ■ K.W. Woodhouse 895
EDITORIAL COMMENTARY
Investigation of the in vivo activity of CYP3A in Brazilian
volunteers: comparison of midazolam and omeprazoEe as
drug markers
A. Rocha ■ E.B. Coelho ■ S.A.P. Moussa ■ V.L. Lanchote 901
Cytochromes P450, induction and cholesterol—what are the
connections?
0. Pelkonen ■ J. Hakkola 837
REVIEW ARTICLES
Cytochrome P450 and gene activation—from pharmacology
to cholesterol elimination and regression of atherosclerosis
P.V. Luoma 841
Efficacy of pregabalin and gabapentin for neuropathic pain
in spinal-cord injury: an evidence-based evaluation of the
literature
T.G.Tzellos ■ G. Papazisis ■ E. Amaniti ■ D. Kouvelas 851
PHARMACODYNAMICS
Slower onset of vasodilating action of brain natriuretic
peptide (BNP) compared to atrial natriuretic peptide (ANP)
in human forearm resistant vessels
H. Minami-T.Yasu -T.Tagawa- K. Yamakawa ■ S. Ueda 859
Influences of levodopa on adipose tissue and skeletal muscle
metabolism in patients with idiopathic Parkinson's disease
F. Adams ■ M. Boschmann ■ E. Lobsien ■ A. Kupsch ■ A. Lipp ■
G. Franke ■ M.C. Leisse ■ J. Janke ■ S. Gottschalk ■ J. Spranger ■
J.Jordan 863
PHARMACOGENETICS
Genetic polymorphism of CYP1A2 and the toxicity of
leflunomide treatment in rheumatoid arthritis patients
P. BohanecGrabar ■ B. Rozman -M.Tomsic- D. Suput ■ D. Logar-V.
Dolzan 871
Systemic exposure of the parent drug oxaliplatin during
hyperthermic intraperitoneal perfusion
H. Mahteme ■ I. Wallin ■ B. GSimelius • L Pahlman ■ H. Ehrsson 907
PHARMACOEPIDEMIOLOGY AND PRESCRIPTION
Antibiotic drug use of children in the Netherlands from
1999 till 2005
J. de Jong ■ P.B. van den Berg ■ T.W. de Vries ■
LT.W.de Jong-van den Berg 913
Incidence and risk factors for agranulocytosis in Latin
American countries—the Latin Study
N. Hamerschlak ■ E. Maluf ■ A. Biasi Cavalcanti ■ A. Avezum Junior ■
J. Eluf-Neto ■ R. Passeto Falcao ■ I.G.H. Lorand-Metze ■ D. Goldenberg ■
C. Leite Santana ■ D. de Oltveira Werneck Rodrigues ■ L.
Nascimento da Motta Passos ■ E.O. de Miranda Coelho ■ M.C.Tostes
Pintao ■ H.M. de Souza ■ J.R. Borbolla ■ R. Pasquini 921
LETTERS TO THE EDITORS
Contrast-media-induced hypersensitivity or allergic/
allergic-like reactions? Suggestion for a more appropriate
use of the nomenclature
[.Bohm-H.Schild 931
"Allergic-like/allergic" or "hypersensitivity" reactions?
An open debate on ADR terminology
F. Lapi ■ A. Mugelli ■ A. Vannacci 933
CYP3A4*1G polymorphism is associated with lipid-lowering
efficacy of atorvastatin but not of simvastatin
Y. Gao-L-r. Zhang- Q . F u 877
Enantiospecific pharmacokinetics of metoprolol in CYP2D6
ultra-rapid metabolizers and correlation with exercise-induced
heart rate
A. Seeringer ■ J. Brockmoller ■ S. Bauer ■ J. Kirchheiner 883
VK0RC1 and CYP2C9 polymorphisms are associated with
warfarin dose requirements in Turkish patients
G. OnerOzgon ■T.Y. Langaee ■ H. Feng ■ N. Buyru -T. Ulutin A.C. Hatemi ■ A. Siva ■ S. Saip ■ J.A. Johnson 889
Further articles can be found at www.springerlink.com Indexed
in/abstracted by Current Contents and Index Medicus.
Instructions for Authors for EurJCiin Pharmacol are available at
www.springer.com/00228.