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Faculty Research Interests Stanford University School of Medicine 300 Pasteur Drive Palo Alto, CA 94305-5105 radiology.stanford.edu/ Gary M. Glazer, M.D. Emma Pfeiffer Merner Professor in the Medical Sciences Professor and Chairman, Department of Radiology Research Interest Body imaging techniques; monitoring therapy of cancer, without biopsy; tissue characterization Department of Radiology Sections: ABDOMINAL IMAGING 300 Pasteur Drive, Room H1307 Stanford, CA 94305-5621 Faculty R. Brooke Jeffrey, M.D. Section Chief and Vice-Chair, Department of Radiology (650) 723-8463 [email protected] Mike Federle, M.D. Associate Chair of Education [email protected] Research Interest Pancreatic MDCT; Thyroid ultrasound/biopsy; Virtual Colonoscopy; Imaging of appendicitis; Hepatic MDCT. MDCT of abdominal trauma and acute abdomen. Imaging (especially CT) of hepatic and pancreatic masses. Innovative teaching materials for radiology and anatomy (print and electronic). Bruce Daniel, M.D. (650) 725-1812 [email protected] MRI of Breast Cancer; MRI-guided interventions, MRIcompatible robotics, and MRI of the prostate. Terry Desser, M.D. (650) 725-1812 [email protected] Imaging of gastrointestinal tract cancer; Ultrasound. Aya Kamaya, M.D. (650) 723-8463 [email protected] Photoacoustic Imaging, gynecologic imaging, thyroid ultrasound and biopsy, US, CT and MR imaging of hepatic malignancies CT perfusion of abdominal malignancies Ultrasound artifacts Robert Mindelzun, M.D. (650) 723-8463 [email protected] Abdominal imaging; Anatomy; Mesenteries; Peritoneum; Omentum; Pancreatic anatomy and embryology; Third World diseases; Abdominal trauma. Matilde Nino-Murcia, M.D (650) 493-5000 [email protected] Gastrointestinal motility in spinal cord injury patients; Use of CT and MRI in imaging liver and biliary tree; Contrast agents for MRI of the gastrointestinal tract and hepatobiliary system; Gastrointestinal motility disorders; Abdominal imaging; Hepatobiliary imaging. Abdominal imaging; Trauma; CT-urography. Eric Olcott, M.D. (650) 493-5000 [email protected] Lewis Shin, M.D. [email protected] F. Graham Sommer, M.D. (650) 723-8463 [email protected] Juergen Willmann, M.D. 650-725-1812 [email protected] Application of real time MRI imaging in patients with Obstructive Sleep Apnea (OSA); Application of real time MRI imaging in evaluation of dyphagia; Magnetic Resonance Colonography - "The Other Virtual Coloscopy;” MRI - Diffusion Weighted Imaging in abdominal/pelvic applications. Research opportunities (med scholars eligible) available for medical students. High-intensity focussed ultrasound for tumor ablation under MR guidance, particularly prostatic and abdominal cancers; Multidetector CT urography; Renal function using CT and MRI; Improved tumor detection using diagnostic ultrasound. Development and translation of molecular imaging approaches in abdominal diseases. BODY MAGNETIC RESONANCE IMAGING Lucas MRS Center, 1201 Welch Road (650) 725-4933 Faculty Robert Herfkens, M.D. Director, Body MRI Research Interest Imaging of myocardial diseases with magnetic resonance, Imaging and spectroscopy. [email protected] Bruce Daniel, M.D. (650) 725-1812 [email protected] MRI of Breast Cancer; MRI-guided interventions, MRIcompatible robotics, and MRI of the prostate. Shreyas Vasanawala, [email protected] Development of new cardiovascular, abdominal, and musculoskeletal imaging techniques with a focus on pediatric MRI. Areas of interest include liver tumors, diffuse liver disease, and renal function. Approaches include novel MR pulse sequences, hyperpolarized imaging, and sodium MRI. CARDIOVASCULAR AND THORACIC IMAGING 300 Pasteur Drive, Room S-072 Stanford, CA 95034-5105 (650) 723-7647 Faculty Ann Leung, M.D. Section Chief, Thoracic Imaging Associate Clinical Chairman (650) 725-0541 [email protected] Geoffrey Rubin, M.D. Section Chief, Cardiovascular [email protected] Research Interest High-resolution computed tomography of the thorax, particularly its application in the setting of acute lung disease in the immunocompromised host; Quantitative assessment of abnormalities using spiral CT; minimizing radiation dose of CT exams. Imaging atherosclerosis and other arterial diseases using CT; Improving radiologist detection of lung nodules with computeraided detection, Cardiac CT. (see also Cardiothoracic Imaging section above) Frandics Chan, M.D. Ph.D. [email protected] Cardiac imaging; Congenital heart disease. Dominic Fleischman, M.D. [email protected] Volumetric CT of the cardiovascular system. INTERVENTIONAL RADIOLOGY 300 Pasteur Drive, Room H3630 Stanford, CA 94305-5642 (650) 725-5202 Faculty Lawrence “Rusty” Hofmann, M.D. Research Interest Image-guided therapies; Molecular interventions. Section Chief [email protected] David Hovsepian, M.D. [email protected] Diagnosis and treatment of vascular malformations; Treatment of symptomatic uterine fibroids using transcatheter embolization and MR-guided focused ultrasound; Quality and Safety in Radiology. Gloria Hwang, M.D. [email protected] Image-guided therapies; Molecular interventions; Pancreatic Interventions; Percutaneous Ablations; and Image-guided Gene Therapies. Nishita Kothary, M.D. [email protected] Many projects for students including case reports, pictorial essays, retrospective clinical studies. Research interests: Image guided interventions in oncology, genetic fingerprinting of HCC. William Kuo, M.D. [email protected] Catheter-directed therapy for acute pulmonary embolism; retrievable IVC filters; endovascular treatment of septic venous thrombosis; and embolotherapy for tumors. John Louie, MD Clinical Assistant Professor [email protected] Image-guided therapies; interventional oncology. Daniel Sze, M.D., Ph.D. [email protected] Transarterial administration of chemotherapeutics, radioactive microspheres, and biologics for the treatment of unresectable tumors; Stent and Stent-graft treatment of peripheral vascular diseases, aneurysms, aortic dissections; Percutaneous treatment of complications of organ transplantation; Treatment of complications of portal hypertension; Catheter-directed thrombolysis of arterial and venous thrombosis and pulmonary embolism. MAMMOGRAPHY Stanford Advanced Medicine Center 875 Blake Wilbur Drive, Room 2234 Stanford, CA 94305-5826 (650) 723-8462 Faculty Debra Ikeda, M.D. Research Interest Breast cancer; breast imaging. Director of Breast Imaging [email protected] MUSCULOSKELETAL IMAGING 300 Pasteur Drive, Room S-056 Stanford, CA 94305-5105 (650) 725-8018 Faculty Christopher Beaulieu, M.D., Ph.D. Section Chief [email protected] Research Interest Imaging and image-guided interventions in sports medicine. New acquisition and visualization methods for MRI and CT. Creation of computer based teaching materials. Sandip Biswal, M.D. [email protected] Molecular imaging of Nociception and Inflammation. (See also MIPS below) Garry Gold, M.D. [email protected] Rapid MRI for Osteoarthritis, weight-bearing cartilage imaging with MRI, and MRI-based models of muscle. New MR imaging techniques such as rapid imaging, real-time imaging, and short echo time imaging to learn more about biomechanics and pathology of bones and joints. Kathryn Stevens, M.D. [email protected] Sports medicine imaging, arthritis, musculoskeletal applications of new MRI sequences. NEURORADIOLOGY 300 Pasteur Drive, Room S-047 (650) 723-7426 Faculty Scott Atlas, M.D. Section Chief [email protected] Research Interest Advanced MRI of the brain; Health care policy; The impact of technology-based medicine in US health care; Role of government in health care; Health care systems in emerging nations; Health care in China. Patrick Barnes, M.D. [email protected] Pediatric Neuroradiology. (See Pediatric Radiology below) Huy Do, M.D. [email protected] Percutanous vertebroplasty as a treatment for painful spinal compression fractures and extra-spinal injection of bone cement (PMMA) for pathologic and non-healing fractures; Cerebrovascular flow dynamics to understand aneurysm and plaque development, Developing medical devices and materials for acute stroke, atherosclerosis, aneurysm, AVM and tumor treatment. Imaging of head and neck disorders, Applications of diffusion and perfusion to head and neck cancer, applications of various diffusion methods to assessing temporal bone cholesteatoma, improved diffusion using reduced field-of-view for spinal cord assessment and assessment of ASL (arterial spin labeled) perfusion in patients with vascular disease of the brain. Nancy Fischbein, M.D. [email protected] Barton Lane, M.D. (650) 493-5000 [email protected] Imaging of head and neck disorders; Vertebroplasty for management of spinal compression fractures; imaging of the spinal cord and spine; treatment of vascular malformations and tumors of the head and neck. Michael Marks, M.D. [email protected] Interventional neuroradiology; Cerebral arteriovenous malformations; Stroke treatment and imaging; Cerebral aneurysms. Kristen Yeom, M.D. [email protected] My primary research interest is in clincal application of advanced MR imaging techniques in pediatric brain tumors. including diffusion, arterial spin labeled perfusion, and functional MRI. We are also interested in translating novel imaging techniques that probe physiologic tumor tissue characteristics. Greg Zaharchuk, M.D., Ph.D. [email protected] Acute imaging of stroke (CT and MRI). Advanced MRI methods, including imaging of brain function, blood flow, and oxygen content. Advanced diffusion imaging of the spinal cord, spinal cord injury. Moyamoya disease. NUCLEAR MEDICINE 300 Pasteur Drive, Room H0101 (650) 725-4711 Faculty Research Interest Sanjiv Sam Gambhir, M.D., Ph.D. Multimodality molecular imaging assays to interrogate molecular/cellular events in living subjects. Division Chief, Nuclear Medicine Division Director, Molecular Imaging Program at Stanford (MIPS) (650) 725-2309 [email protected] Michael Goris, M.D., Ph.D. [email protected] Radio-immunotherapy; Medical Imaging Processing; Quantification for diagnosis; Clinical validations. Andrei Iagaru, MD [email protected] Whole-Body MRI and F-18 PET in Osseous Metastases Detection; Zevalin/Bexxar Therapy; Combined F-18 and F-18 FDG PET/CT for single scan cancer detection; PET-CT for Thyroid/Breast Cancer, Melanoma, Lymphoma, and Sarcoma. Andrew Quon, M.D. [email protected] Multimodality fusion imaging with PET, CT, and MRI for oncology; Translational research bringing new radiotracers to clinical use; Cardiovascular multimodality PET/CT imaging. George Segall, MD (650) 493-5000 PET/CT myocardial perfusion imaging and CT coronary arteriography. PEDIATRIC RADIOLOGY 725 Welch Road (650) 725-2548 Faculty Richard Barth, M.D. Section Chief [email protected] Research Interest Sonographic and magnetic resonance imaging of fetal congenital anomalies; Imaging of fetal renal anomalies, lung masses, and GI anomalies. Patrick Barnes, M.D. [email protected] Advanced imaging, including magnetic resonance imaging, of injury to the developing central nervous system including fetal, neonatal, infant and young child, and nonaccidental injury (e.g. child abuse). See also Neuroradiology, above. Francis Blankenberg, M.D. [email protected] Molecular imaging. (See also MIPS below) Frandics Chan, M.D. Ph.D. [email protected] Cardiac imaging; Congenital heart disease. John MacKenzie, M.D. Chief of Pediatric Musculoskeletal Imaging [email protected] Bone and joint imaging. Arthritis imaging. Molecular imaging of childhood disease. Current projects include MRI of sacroiliitis and hyperpolarized carbon-13 imaging of arthritis and gene therapy. Beverly Newman, B.Sc., MBBCh. [email protected] Pulmonary and Cardiac imaging in Children. Neonatal Imaging. Radiation dose reduction. William Northway, M.D. Emeritus [email protected] Erika Rubesova, M.D. [email protected] Neonatal pulmonary imaging. Shreyas Vasanawala, [email protected] Our work is focused on developing and evaluating novel strategies to obtain faster and sharper magnetic resonance images. Target applications span the spectrum of body imaging, including cardiovascular, abdominal, pelvic, and musculoskeletal imaging. Kristen Yeom, M.D. [email protected] My primary research interest is in clincal application of advanced MR imaging techniques in pediatric brain tumors. including diffusion, arterial spin labeled perfusion, and functional MRI. We are also interested in translating novel imaging techniques that probe physiologic tumor tissue characteristics. Perinatal imaging including fetal imaging (US and MRI) and abdominal imaging in children. Radiological Sciences Laboratory (RSL) Located at: Richard M. Lucas Center for Magnetic Resonance Spectroscopy and Imaging rsl.stanford.edu/research/lucas_center.html or rsl.stanford.edu RSL Faculty Gary Glover, Ph.D. Director, RSL (650) 723-7577 [email protected] Research Interest Rapid MRI methods using non-cartesian k-space trajectories; Applications to functional MRI and contrast uptake in the breast. Norbert Pelc, Sc.D. Associate Chair for Research, Radiology (650) 723-0435 [email protected] New CT systems and reconstruction methods; Hybrid imaging systems; Digital X-ray imaging Roland Bammer, Ph.D. (650) 498-4760 [email protected] Parallel MRI; Perfusion- and diffusion-weighted MRI. RSL Faculty Research Interest Kim Butts-Pauly, Ph.D. (650) 725-8551 [email protected] MRI-guided minimally invasive therapies; High intensity focused ultrasound; MRI-guided cryoablation; Interventional MRI; Rapid MR imaging; Motion corrected MRI; Artifact reduction MRI. Rebecca Fahrig, Ph.D. (650) 724-3559 [email protected] Image Guidance during Interventional Procedures (Combined C-arm CT and Fluoroscopy for Neurointerventions; Retrospectively-gated Multi-sweep Cardiac C-arm CT for Guidance during Cardiac interventions; Real-time tomosynthesis; Development of new hardware for MRcompatible X-ray fluoroscopy). Also CT reconstruction, image artifact reduction, hardware design (X-ray tubes) and optimization (digital flat-panel detectors), and in-vivo optimization and validation of imaging protocols. Brian Hargreaves, Ph.D. (650) 498-5368 [email protected] Body MRI including abdominal, breast and cardiovascular applications; Rapid MRI techniques; MRI contrast mechanisms; Optimization in MRI sequence design. Michael Moseley, Ph.D. (650) 725-6077 [email protected] High-speed MRI techniques to image and measure water proton diffusion and contrast-enhanced tissue blood perfusion; Detection of the earliest effects of experimental and clinical cerebral ischemia; Assessing integrity of cerebral white matter. Brian Rutt, Ph.D. [email protected] Daniel Spielman, Ph.D. (650) 723-8697 [email protected] High Field MRI, MR Engineering, Cellular and Molecular MRI, Neuro MRI, and quantitative MRI. MR Spectroscopic imaging, 1H MRS of the human brain, metabolic imaging of small animal models using hyperpolarized 13C MRS. Information Sciences in Imaging at Stanford (ISIS) ISIS Faculty Sandy Napel, Ph.D. Co-Director, ISIS (650) 725-8027 [email protected] Research Interest Developing diagnostic and therapy-planning applications and strategies for the acquisition and visualization of multidimensional medical imaging data, e.g., 3D images of blood vessels, computer-aided detection and characterization of lesions (e.g., colonic polyps, pulmonary nodules) from crosssectional image data, visualization and automated assessment of 4D ultrasound data, and fusion of images acquired using different modalities (e.g., CT and MR), advanced visualization for interventional applications. ISIS Faculty Research Interest Sylvia Plevritis, Ph.D. Co-Director, ISIS 650) 498-5261 [email protected] Correlation of imaging data to genomic and proteomic signatures and clinical outcomes; Outcomes research, particularly related to cancer screening programs; Medical decision analysis. David Paik, Ph.D. (650) 736-4183 [email protected] Developing and validating computational methodologies for extracting useful information content from anatomic, functional and molecular images, drawing upon image processing, computer vision, computer graphics, computational geometry, machine learning, biostatistics, modeling and simulation. Integrating image-based information with non-imaging biomedical information. Medical informatics and bioinformatics; correlating imaging to pathology and molecular data; making the meaning in images computer-accessible; ontologies; “just-in-time” information and decision support to reduce variation in radiology practice; imagebased computer reasoning, electronic teaching files, quality assessment, data warehouses/mining, and Web technologies for radiology. Daniel Rubin M.D., M.S. (650) 725-5693 [email protected] Molecular Imaging Program at Stanford (MIPS) Located at: James H. Clark Center, 318 Campus Dr., East Wing, 1st Fl. mips.stanfordedu or biox.stanford.edu MIPS Faculty Research Interest Sanjiv Sam Gambhir, M.D., Ph.D. Multimodality molecular imaging assays to interrogate molecular/cellular events in living subjects. Director, MIPS Division Chief, Nuclear Medicine Division (650) 725-2309 [email protected] Sandip Biswal, M.D. (650) 498-4561 [email protected] Using multimodality molecular imaging techniques to study musculoskeletal pain, arthritis, inflammation and nociception. (see also Musculoskeletal section above) Francis Blankenberg, M.D. (650) 497-8601 [email protected] Molecular imaging of tumor angiogenesis in oncology patients; Molecular imaging of apoptosis. (see also Pediatric Radiology section above) Xiaoyuan (Shawn) Chen, Ph.D. (650) 725-0950 [email protected] Developing and validating novel molecular imaging probes for visualization and quantification of molecular targets that are aberrantly expressed during tumor growth, angiogenesis and metastasis as well as other angiogenesis related diseases; nanoplatform-based molecular imaging and drug delivery; imaging stem cell trafficking and targeted gene delivery. MIPS Faculty Research Interest Zhen Cheng, [email protected] Molecular imaging of cancer and its metastasis, identifying novel cancer biomarkers with significant clinical relevance, development new; chemistry for imaging probes preparation, validating new strategies; for imaging probes high-throughput screening. Samira Guccione, Ph.D. (650) 725-4936 [email protected] Multimodality imaging, vascular contrast agents; Molecularly targeted platforms for combined imaging and therapy (including gene and chemotherapies); Focused ultrasound mediated drug delivery including targeted and non-targeted temperature sensitive liposomes; Polymeric, implantable, drug delivery systems for controlled release of drugs over time; Effects of new 'biological' chemotherapies as reflected in various functional imaging techniques; Genomic and proteomic evaluation of clinical tissue and fluid samples. Craig Levin, Ph.D. (650) 736-7211 [email protected] Development of novel imaging technology to advance the in-vivo visualization and quantification of cellular and molecular signatures of disease. Jianghong Rao, Ph.D. (650) 736-8563 [email protected] Nanoparticle-based sensors for in vitro tumor detection and in vivo imaging; in vivo imaging of RNA; CT contrast agents for tumor-specific molecular imaging. Juergen Willmann, M.D. 650-725-1812 [email protected] Development and clinical translation of novel molecular and functional imaging biomarkers with special focus on imaging abdominal, pelvic and breast cancer as well as inflammatory bowel disease. - Development of molecular ultrasound contrast agents for early cancer detection and cancer treatment monitoring. Joseph Wu, M.D., Ph.D. (650) 736-2246 [email protected] Molecular imaging of adult stem cells, embryonic stem cells, and induced pluripotent stem cells; Gene therapy; Genomics. 3D Medical Imaging Laboratory (3D Lab) Located at: Richard M. Lucas Center for Magnetic Resonance Spectroscopy and Imaging and the James H. Clark Center 3dradiology.stanford.edu 3D Lab Faculty Research Interest Geoffrey D. Rubin, M.D. Imaging atherosclerosis and other arterial diseases using CT; Director, 3D Lab [email protected] Improving radiologist detection of lung nodules with computeraided detection, Cardiac CT. (see also Cardiothoracic Imaging section above) Sandy Napel, Ph.D. Developing diagnostic and therapy-planning applications and strategies for the acquisition and visualization of multidimensional medical imaging data, e.g., 3D images of blood vessels, computer-aided detection and characterization of lesions (e.g., colonic polyps, pulmonary nodules) from crosssectional image data, visualization and automated assessment of 4D ultrasound data, and fusion of images acquired using different modalities (e.g., CT and MR), advanced visualization for interventional applications. Imaging informatics including how biological information is extracted from both anatomic and molecular imaging, how it is represented, how it is modeled and how it is disseminated with an outlook toward how this imaging-derived information can be combined with other sources of biological and clinical information. co-Director, 3D Lab (650) 725-8027 [email protected] David Paik, Ph.D. (650) 736-4183 [email protected] Christopher F. Beaulieu, M.D., Ph. D. (650) 725-8018 [email protected] Three dimensional imaging, CT colonography, computer aided detection algorithms and clinical applications. Use of medical informatics to link image features with controlled terminology. Radiology Interest Group at Stanford website: rigs.stanford.edu Department of Radiology website: radiology.stanford.edu Radiology residency website: xray.stanford.edu Links to research programs: xray.stanford.edu/applicants/research.html