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Transcript
under the patronage of
Organised by
In association with
HRH Sultan Muhammad V The Sultan of Kelantan, Malaysia
Kelantan Government
Malaysia
12th Malaysian Conference and Exhibition on Anti-Aging,
5
Aesthetic and Regenerative Medicine
&
th
International Congress on Anti-Aging, Aesthetic and
Regenerative Medicine
BEAUTY &
WELLNESS
THRU’ NUTRITION
Organised by
Society for Anti-Aging, Aesthetic and
Regenerative Medicine Malaysia (SAAARMM)
Dates:
1st - 3rd May 2015
Venue:
Nusantara Ballroom, Sheraton Imperial Kuala Lumpur, Malaysia
In collaboration with
Supported by
Souvenir Programme
and Abstracts
SCIENTIFIC SESSIONS
ABSTRACTS
Only abstracts that have been received are included herein.
The abstracts contained within are printed as received.
The views stated within are solely those of the authors/speakers, unless expressed.
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uninfluenced by this fact.
Kindly take note that the exhibitors and their products merely serve as
information to delegates as to what is available in the market and in no
way suggests that they are endorsed by the Society. The onus is on
the prescribing practitioner to verify the claims of the products and to
ensure they comply and/or are registered with the relevant authorities
under the appropriate Malaysian rules and regulations
21
Mitochondrial Nutrients in Anti-Aging
Dr A Sreekumar MBBS, DLO, MACNEM
Founder President - Indian Nutritional Medical Association (INMA)
Chairman - Wellness Solutions, Kundnnur, Kochi, India
Consultant in Nutritional Medicine
Senior ENT Consultant / Head and Neck Surgeon
India
Today we are living in an era of scientific and technological extravaganza. Medical care also has to change
with times and we doctors should understand and update ourselves accordingly. This presentation is mainly
aimed at giving an insight into the latest in science and cellular medicine. This is going to stay as the only
evidence based scientific health care. We are moving into an era of data-driven, crowd sourced, participatory,
genomics-based medicine. In the immediate past patients were resorting to second opinion for their health
problems. This is changing to net based approach - information at your fingertip any time. This more updated
than any medical books. A doctor should be aware about genome, cellular mechanism and environment.
Today we are all aware about the fact that Biochemistry, Genetics, Biophysics, and Nano science reveal the
basics in life. Role of mitochondria, how to maintain its function and problems with mitochondrial dysfunction
are all touched upon in this presentation.
We should be well versed with intra cellular organelles especially mitochondria where energy manufacture
happens. Life of a cell depends on this and indirectly determines the state of disease and health.
Understanding the mechanism and ways to improve the strength of mitochondria hold the key to prevent
disease and improve health. This underlines the real essence of anti-ageing medicine. Throughout this talk
basic mitochondrial mechanism is revealed and the real evidence based holistic approach (3 dimensional)
in health care.
In Albert Einstein’s words “physical body is an illusion and trying to manipulate it is like grasping shadow and
really miss the substance”.
You can change your world by changing your perception.
22
Nutrigenomics in Lifestyle Diseases
Dr A Sreekumar MBBS, DLO, MACNEM
Founder President - Indian Nutritional Medical Association (INMA)
Chairman - Wellness Solutions, Kundnnur, Kochi, India
Consultant in Nutritional Medicine
Senior ENT Consultant / Head and Neck Surgeon
India
In this era of fast modern world, man has to respond and adjust life to environment toxins, low nutrient
density of food, chemical fertilizers in agriculture, unscientific food storage, cooking and utensils. This has
reached a stage where man live in fear, fear for everything even to the most essential things in life like glucose
and cholesterol. In fact this fear is the reason for almost all diseases of today and this stage is actually due
to interaction of trillions of human and nonhuman cells. In medical practice understanding of this is very
important.
Nutrigenomics refers to nutrition based on one’s genome expression. This could also refer to “personalized
health care” and nutrition. The stress is on diet and nutritional therapy for the person rather than for a
particular disease. This discussion is mainly on epigenetics meaning beyond genes. Identifying one’s genome
expression and understanding measures to block or modify it for a person’s benefit is highlighted. This offers
hope to those who know they have a strong family history of heart disease, cancer, diabetes, obesity, and
most likely many other diseases as well. Over the years nutritional therapy failed because minimal amount
required for optimal health should be at the genomic level, and Nutrigenomics is the solution.
This is beneficial not only for personalized prevention, but also for personalized pharmacotherapy, emergency
medicine and specialty clinics especially in neuro-degenerative diseases, diabetes, toxicology and psychiatric
diseases. Understanding the latest in science is essential for the best health care. It’s the correlation of
epigenome and exposome hold the key for personal preventive medicine. This is to make one understand that
the basis of nutrition is impact of nutrients on epigenetic adjustments, understanding of patho-biochemistry
of disease, genetics of individual to know predisposition and promote re programming through epigenetics.
We, as doctors should be responsible for effective translation of genome based knowledge for the benefit of
population health by effectively practicing it and spreading the message.
23
Nutritional and Botanical Cancer Therapies
and Individualized Testing for Sensitivities
Dr Joachim Fluhrer
BA Naturopathy (Wetzlar), MB BS (Sydney University)
Fellow of ACNEM (Melbourne)
Vice President and Senior Lecturer
Australian College of Nutritional and Environmental Medicine (ACNEM)
Victoria, Australia
The biology of cancer and individual cancer cells is complex and is a constant source of research and learning.
One thing is for certain, cancers and cancer cells are heterogeneous and we have to learn to individualize our
diagnostic approach and therapies.
Pharmacological therapies have focused on inhibiting certain pathways and receptors with chemotherapy
agents, monoclonal antibodies and small molecules. The targets for treatment are often guided by mutation
analysis of cancer cells. However, this is not the subject of this presentation.
Nutritional and botanical medicines are in common use in many medical treatment systems, such as
Traditional Chinese Medicine, Ayurvedic Medicine and Integrative Western Medicine. There has been a
wealth of knowledge accumulated in traditional data collection methods and practitioner experience. Better
biochemical and genetic understanding have supported the modern understanding of the effect of botanicals
and high dose nutrients.
A review of some of the pathways through which these medicines work, which receptor they may be blocking
or enhancing, and which gene expression they are modulating will be explored in this presentation. Practical
demonstration of selective biochemical and genetic testing including testing for sensitivity and/or resistance
to botanicals and nutrients utilizing Circulating Tumour Cells (CTCs), Polymorphism and Genomic Testing will
form a core of this presentation.
The focus will be on agents such as Vitamins C and D, CoQ10, Botanicals such as Curcumin, Artemisia,
Amygdalin, fermented Soy Extracts and DCA.
24
Global Growth of Anti-Aging and Regenerative Medicine
Prof Dr Robert Goldman MD, PhD, DO, FAASP
Chairman
American Academy of Anti-Aging Medicine
Worlld Anti-Aging Academy off Medicine
USA
Around the world, people are seeking medical guidance for ways to stay healthy, active, and vital well into
their older years. The exponential growth in the popularity of anti-aging medicine is largely a result of the
global demographics shift towards a swelling aging population. The United Nations observes that: “The
world is in the midst of a unique and irreversible process of demographic transition that will result in older
populations everywhere. As fertility rates decline, the proportion of persons aged 60 and over is expected to
double between 2007 and 2050, and their actual number will more than triple, reaching 2 billion by 2050. In
most countries, the number of those over 80 is likely to quadruple to nearly 400 million by then.”
[Reported by http://www.un.org/en/globalissues/ageing/index.shtml]
Anti-aging medicine is a clinical specialty founded on the application of advanced scientific and medical
technologies for the early detection, prevention, treatment, and reversal of age-related dysfunction, disorders,
and diseases. It is a healthcare model promoting innovative science and research to prolong the healthy
lifespan in humans. As such, anti-aging medicine is based on principles of sound and responsible medical
care that are consistent with those applied in other preventive health specialties. The phrase “anti-aging,”
as such, relates to the application of advanced biomedical technologies focused on the early detection,
prevention, and treatment of aging-related disease.
Multinational companies are pouring billions of dollars into anti-aging medical technologies. In particular,
Silicon Valley has engaged significant resources.
Google backs privately held 23andMe, which offers a DNA test for consumers who can secure genetic reports
and ancestry-related data. In 2013 by Google’s CEO and co-founder, Larry Page - 40 years old at the time,
founded Calico (California Life Company) with $1 billion in start-up funding. Describing its goal as “focusing on
the challenge of aging and associated diseases.” Page has observed that: “With some longer term, moonshot
thinking around healthcare and biotechnology, I believe we can improve millions of lives.” Calico is headed by
Art Levinson, former CEO of Genetech, a highly successful biotech company specializing in cancer therapies.
[“Anti-ageing drugs may have been developed,” Independent, co.uk, 2 October 2014.]
In mid-2014, Calico forged a 10-year R&D collaboration deal with AbbVie Inc., a major US drugmaker (notably,
Humira®, a rheumatoid arthritis biologic). Each company is reported to invest an initial $250 million, with a
possible additional $500 million in the future. Using this funding, Calico will use its scientific expertise to
establish a world-class research and development facility and AbbVie will use its commercial expertise to
bring the new drugs discovered in this facility to market.
[Google’s Calico, AbbVie forge deal against diseases of aging,” Reuters.com. 3 September 2014; “Can
Google’s Calico develop a cure for death?” Nanlyze.com, 4 September 2014.]
In early 2014, US scientist Craig Venter, who mapped the Human Genome a decade ago, founded 22 Human
25
Longevity, Inc. With $70 million in its first round of private funding and prominent Asian real estate developers
as key investors, the company aims to take a genome-based approach “to tackle the diseases associated
with aging-related human biological decline.”
[“Anti-ageing drugs may have been developed,” Independent, co.uk, 2 October 2014.]
The notion that “aging is not inevitable” now resonates with entities that are poised to have a major, lasting,
and beneficial impact in the field. It is interesting, as well, to note that each of these mega corporations proudly
equates themselves with “anti-aging.” As such, the phrase “anti-aging” is now poised for transformation from
a disparaged term to one of prestige and dominance.
Today, thousands of physicians and practitioners in private medical offices, as well as at some of the most
prestigious teaching hospitals around the world, now embrace the anti-aging medical model. As a patientcentric, wellness-oriented model of advanced clinical preventive medicine, the principles of the anti-aging
medical model are gaining rapid and widespread acceptance as a framework for lifelong habits for healthy
living. This innovative medical specialty is achieving demonstrable and objective results that beneficially
impact the degenerative diseases of aging.
Learning Objectives:
1. Introduction to the importance of the anti-aging and regenerative medical specialty
2. Primer on the applications of anti-aging and regenerative medicine in the clinical setting
3. Review the society-wide implications of anti-aging and regenerative medical technologies
26
Introduction to Injectable Nutrients
Dr Joachim Fluhrer
BA Naturopathy (Wetzlar), MB BS (Sydney University)
Fellow of ACNEM (Melbourne)
Vice President and Senior Lecturer
Australian College of Nutritional and Environmental Medicine (ACNEM)
Victoria, Australia
This presentation/workshop is subject to a “Certification of Attendance”, a pathway for a 3 day Advanced
Course Certification in Injectable Nutrients and Medical Nutrition in September 2015.
In collaboration with ACMN, the Australasian College of Medical Nutrition.
Nutrients play a part in every biochemical process in the body. For the body to function optimally, these
nutrients need to be present in sufficient quantities, in the right form and in balance with each other. Nutrients
include vitamins and minerals. Ideally, we obtain most of our nutrients through our diet and through
processes within the body, including the action of bacteria in the gut. However, there are circumstances
- such as disease, stress, etc. - in which sufficient nutrients may not be obtainable through the diet. In
such cases, supplementation may be advisable. Medical Nutrition is the clinical application of the current
substantial knowledge about the roles played by nutrients in health and disease. A doctor trained in Medical
Nutrition can investigate a person’s nutritional status and can then suggest nutrient therapies, which could
assist in achieving optimal health, preventing disease or fighting existing disease. In some cases, the best
form of delivery of nutrients is through intravenous or intramuscular injection. This may be because: large
doses, if taken orally, may adversely affect the gut; the person may have problems with absorption; the best
form of the nutrient may not be well tolerated if taken orally; or a rapid response is needed, which may not
be achieved through oral supplementation. To practice injectable nutrient therapy properly, a doctor needs
to have undertaken some study beyond that offered in any medical school in this country. The Australasian
College of Medical Nutrition offers such extra, specialised training. The training is based on both published
clinical trials and the extensive clinical experience of the faculty members. The training encompasses the
theoretical (biochemical) underpinnings of this science and the practical application of these to individual
patients in the doctor’s surgery. It includes investigation of nutritional status, relating that to the individual’s
state of health and the formulation of a treatment program, which may also include available orthodox
medicine, such as pharmaceutical drugs. The trained practitioner of Medical Nutrition is also aware of the
interactions, which take place between various nutrients, and, more importantly, the possible interactions
between nutrients and pharmaceutical drugs. Such a practitioner also knows how pharmaceutical drugs
use and possibly deplete nutrients in the body and s/he can, through appropriate supplementation, help
avoid many of the side effects of drug therapy. The practitioner of Medical Nutrition is a holistic doctor,
integrating the knowledge and experience of nutrient therapies with orthodox, western medicine. This
gives the patient the best that modern medicine can offer, including the avoidance of unnecessary use of
pharmaceutical drugs.
(Extract from www.nutritioncollege.org about Medical Nutrition)
A 3-day hands-on training enables the participant to use reliable, convenient therapies in your clinical
setting to prevent and treat chronic diseases and confidently, safely apply IV and IM delivery of vital healing
nutrients both individually and in combinations.
27
Cancer Therapy - Nutritional Perspective
and Role of Injectable Nutrients
Dr A Sreekumar MBBS, DLO, MACNEM
Founder President - Indian Nutritional Medical Association (INMA)
Chairman - Wellness Solutions, Kundnnur, Kochi, India
Consultant in Nutritional Medicine
Senior ENT Consultant / Head and Neck Surgeon
India
Cancer is one of the most dreadful diseases of mankind affecting younger age groups and badly interferes
with morbidity, quality of life and death. Therapeutic approach has grown with technology, but has not been
successful in containing it or in managing it.
Personalized Nutritional therapy has been found to be useful in prevention as well as in treatment protocols.
Treatment protocols can be in the tune of complementary and palliative therapy helping in improving quality
of life and life span. A lot of clinical trials are already underway in various centres for first line management
of cancer. Assessing the metabolic level of the patient and understanding methylation has revolutionized
nutritional therapy. Importance is mainly on injectable nutrients that can function as therapeutic tool. Latest
clinical trials and various combination nutrition therapy is discussed in this presentation. Dosage and mixing
are very important, and doctors, nurses and paramedics should be trained for better understanding and
future. In all sections of cancer management, nutritional therapy holds the hope for future therapy without side
effects and improved quality of life.
28
Skin Aging
Prof Dr Sudigdo Adi MD PhD
Chief of Post Graduate Programme
Medical Aesthetic and Anti-Aging
Medical Faculty
Padjadjaran University
Bandung, Indonesia
Skin is the outermost organ that serves as one of the body’s defence against exposure or surge of substances
or foreign objects from outside the body. In terms of medical cosmetology, skin is one of the organs which
takes attention of those who want to get a good and healthy look. The process of skin aging is similar to the
other tissues that starts from the beginning of human conception until death. The aging process is influenced
by the internal factors at the cellular and molecular levels and also the external factors.
At the cellular level, the aging process is influenced by several factors, as the rate of mitosis of the cells,
by oxidative stress at the cellular metabolism, telomere shortening, that caused by mitosis process and
mitochondrial DNA mutations during mitosis and the influence of various growth hormones, while the external
influences are the exposure to ultraviolet A and B especially from the sun since the UVC is protected by the
atmosphere layers before it reaches the human life environment. This basic knowledge about the effects of
the aging process can explain the aging process generally and especially of the skin.
29
Cellular Extracts and Biomedical Diagnostic
and Therapeutic Devices
Sponsored by NEXGEN Biopharma
Dr Dina Tukhvatullina PhD
Medical Advisor
Labdom Suisse
Carouge, Switzerland
Swiss Biological Medicine is not a new phenomenon but has evolved into protocols that are showing increasing
success in the treatment of cancers and auto-immune diseases. The fundamental of biological medicine is to
focus on the body’s natural ability to protect and heal. Today biological medicine has been a proven success
to patients who frequent specialised clinics in Switzerland, for example.
Therapies include comprehensive diagnosis protocol to investigate using safer non-radiation Bio Radiometry
Total Scanner for early cancer prevention scan (8-10 year), Bio Med Scan to examine internal self-regulating
processes of the human body, and treatment with Bio Hormonal Modulator to stimulate and regulate the
Pituitary Gland whilst combining treatment with specific oral cell extrac.
Regeneration with Specific
Bio-molecular Peptide Therapies
Sponsored by NEXGEN Biopharma
Dr Dina Tukhvatullina PhD
Medical Advisor
Labdom Suisse
Carouge, Switzerland
Modern range of specific peptide therapy includes a new generation of natural based therapy by Myopep,
Regenapep and Enchancepep. Myopep is a peptide that blocks the effect of myostatin. It results in acceleration
of metabolic activity in the fat tissue, and decreases regeneration of the fat. Persons who practice at least
moderate (or high) physical activities will notice dramatically growth of muscle and improvement of the body
shape together with 2-3 months of Myopep application. Additionally Myopep also decreases blood pressure,
triglyceride and cholesterol level, and concentration of both fasting glucose and diabetic hemoglobin (Hb
A1C). Bio-engineered as an outstanding inflammatory cascade blocker, Regenapep is capable of inducing
suppressive effect on the development of chronic systemic inflammations. This peptide-derived interleukin
blocker has the ability to down regulate elevated inflammation markers with outstanding effectiveness by
specifically inhibiting selective interleukins and blocking the production of prostaglandins - the regulatory
molecules. Enchancepep includes several important effects like Inhibiting phosphodiesterase 5 (PDE-5) and
stimulating Alpha-Melanocyte Stimulating Hormone. It results in natural increase of blood flow to the sexual
organs, enhance sex drive and improve of libido, sexual performance and improvement on sensitiveness
day-to-day. All these unique peptides are developed on the base of natural colostrum as well as specific
ingredients from the plants. Thus, they are natural and safe to use.
30
The Aging Skin
Dr Kuljit Singh
Medical Director
Consultant Aesthetic Physician
Damansara Height Wellness Clinique
Kuala Lumpur, Malaysia
Aging is a natural process that takes place in every individual. For example, the aging process begins at the
surfaces and subsurface structural changes in multiple facial tissue layers including skin, fat, muscle and
bone.
Aging of the skin happens within the tissue layers. Changes in one of the tissue layers have an effect on the
other tissue layers as well. Furthermore, as we age the skin undergoes several changes at the same time.
Collagen also plays a major role in the skin aging process. When the skin losses or lacks in collagen therefore
this unables it to retain its elasticity and moisture further causing it to be dry and thin.
Fat plays an important role in having a youthful looking skin. Having the right amount of facial fat at the right
places is important in order for an individual to have that youthfulness look. Redistribution, accumulation and
atrophy of fat also lead to facial volume loss. Some areas tend to lose fat like the forehead and cheek whereby
other parts tend to gain fat like the mouth and jaw areas of the face. Modifications on the fat pad may also
lead to contour deficiencies.
As we age there is also a significant loss of the facial bone. Aging of the craniofacial skeleton may be due to
changes in the relative dynamics of bone expansion and bone resorption. Bone resorption can also lead to
biometric volume loss. Therefore, without the structural support from the bone, noticeable changes will occur
in other layers of overlying tissue and skin.
Nevertheless, with the advanced medical research present these days, treatments can be done to further
delay the aging process.
31
Nutrition in Aesthetic Medicine
Dr Leela Velusamy
MBBS (India), Masters Social Science (Skilled Dermatology)
University Herdfordshire, FICGP FIAMS (Hons), AARAM (USA)
Masters in Cognitive Mental Illness (UK)
Poliklinik Vishu
Seremban, Malaysia
As with all other branches of Medicine, nutrition and fitness play significant roles in helping the patient
achieve their desired goals. The main goal most patients’ desire is to delay the onset of aging.
Unfortunately, in many instances, a starved and undernourished physique is assumed to be desirable.
We, as medical professionals must remember, primum non-nocere, do no harm. Therefore, it is our
responsibility to ensure the patient achieves what they want without harming themselves in our
jurisprudence. Weight loss is often mistaken for fat loss. Weight loss can be achieved by malnutrition,
anorexia and other such pathologies. Fat loss, however, can only be achieved by a well-planned diet
regime and exercise. It is therefore obvious which of the two is desirable.
Another aspect of Nutrition in this field is the maintenance of youthful skin which again is a vast topic
to be discussed. Certain molecules in the food we consume may protect from free radical damage,
responsible for mitochondrial shut down and cell death.
Therefore, a wholesome approach to Aesthetic Medicine can only be achieved by a sound understanding
of Nutrition and its application in a clinical setting.
32
Basics of Lasers
Sponsored by Customedz
Dr Leroy Rebello
D.Derma, PhD, ACLS
Director
Eternesse Anti Aging Clinic
India
Laser Skin Resurfacing
If aging, acne, or too much time in the sun has left your face with blotches, scars, wrinkles, or lines, laser skin
resurfacing may help your skin look younger and healthier.
Laser skin resurfacing removes skin layer by layer with precision. The new skin cells that form during healing
give the skin a tighter, younger looking surface. The procedure can be done alone or with other cosmetic
surgeries on the face.
Preparing for Laser Resurfacing
Start by consulting a plastic surgeon or dermatologist to find out if you’re a good candidate.
Tell your doctor if you get cold sores or fever blisters around your mouth. Laser skin resurfacing can trigger
breakouts in people who are at risk.
If you decide to go ahead with laser skin resurfacing, your doctor will ask you to not take any medications
or supplements - such as aspirin, ibuprofen, or vitamin E - that can affect clotting for 10 days before surgery.
If you smoke, you should stop for two weeks before and after the procedure. Smoking can prolong healing.
Your doctor may prescribe an antibiotic medication beforehand to prevent bacterial infections and also an
antiviral medication if you are prone to cold sores or fever blisters.
What to Expect During and After the Procedure Laser resurfacing is done by a plastic surgeon or dermatologist.
It’s an outpatient procedure, meaning you’ll not have to stay overnight.
The doctor may treat wrinkles around your eyes, mouth, or forehead individually or treat your entire face. For
small areas, the doctor will numb the areas to be treated with a local anesthetic and may also sedate you. You
may get general anesthesia if your whole face is being treated.
Treating just parts of the face takes about 30 to 45 minutes. A full-face treatment takes up to two hours.
33
Following the laser procedure, the doctor will bandage the treated areas. After 24 hours, you will need to clean
the treated areas four to five times a day and then apply an ointment such as petroleum jelly to prevent scabs
from forming.
Swelling after laser skin resurfacing is normal. Your doctor may prescribe steroids to manage swelling around
your eyes. Sleeping on an extra pillow at night can also ease swelling.
You may feel itching or stinging for 12 to 72 hours after the procedure. Five to seven days after laser resurfacing,
your skin will become dry and peel.
Depending on the problem that was treated, healing typically takes 10 to 21 days. Once the skin heals, you
can wear oil-free makeup to minimize redness, which usually fades in two to three months.
You will also probably notice that your skin is lighter for a while after surgery. It is particularly important that
you use a “broad-spectrum” sunscreen, which screens ultraviolet B and ultraviolet A rays, to protect your skin
during that time. When selecting a sunscreen, look for one specially formulated for use on the face with a sun
protection factor (SPF) of 30 or higher. Limit your time in the sun, especially between the hours of 10.00 a.m.
and 2.00 p.m., and wear protective clothing, such as long-sleeved shirts, pants, and a wide-brimmed hat.
It is also important to keep your new skin well moisturized. If you use Retin A or glycolic acid products, you
should be able to start using them again after about six weeks or when the doctor says you can.
Benefits and Risks of Laser Resurfacing
Although skin resurfacing cannot produce perfect skin, it can improve the appearance of your skin. Potential
risks of the procedure include.
Burns or other injuries from the laser’s heat Scarring Changes in the skin’s pigmentation, including areas of
darker or lighter skin Reactivating herpes, cold sores and Bacterial infection.
34
Advances in PRP with EMF Technology
Sponsored by Customedz
Dr Leroy Rebello D.Derma, PhD, ACLS
Director
Eternesse Anti Aging Clinic
India
In recent years there have been many advances in PRP in the field of cosmetology and orthopaedics and
anti-aging medicine. Today we use HPL (human platelet lysate) which is one of the most advanced forms of
PRP. Human platelet lysate is prepared from PRP. This is achieved by heat and thaw cycles.
Platelet Rich Plasma, or PRP, is blood plasma with concentrated platelets and other growth factors. The
concentrated platelets found in PRP contain huge reservoirs of bioactive proteins, including growth factors
and signaling proteins that are vital to initiate and accelerate tissue repair and regeneration. These growth
factors number at least a dozen different factors. These bioactive proteins initiate connective tissue healing in
tissues such as meniscus (knee) and rotator cuff tissue, bone and articular cartilage regeneration and repair,
promote development of new blood vessels, and stimulate the wound healing process.
Platelet Rich Plasma therapy is a treatment option for various orthopaedic injuries and conditions, which have
traditionally required surgery or other extensive treatments. PRP injections are being utilized in orthopaedics
with increasing frequency and effectiveness. Injuries currently being treated with the PRP therapy are arthritis
of the hip, knee, shoulder, ankle and other joints. PRP also is utilized for soft tissue injuries such as tendonitis,
muscle sprains and tears, and various types of ligament injuries. These include common tendon injuries
such as tennis and golfers’ elbow, Achilles tendonitis and knee tendonitis. PRP with HPL is also used to treat
various injuries and conditions affecting (joint) injuries. These include rotator cuff and meniscus injuries.
Although PRP technology is considered cutting edge technology, it was initially developed 20 years ago for
heart surgery to aid with the wound healing and blood loss. Its benefits are now being applied towards the
facilitating of healing muscle, tendons, ligaments, articular and meniscal injuries. In fact, PRP has been widely
used in Europe for many years.
Other indications for PRP
Wound Healing
Bone Fracture and healing
Dental Application
Hair transplant
Soft tissue regeneration
Face rejuvenation
35
PRP with HPL is a technology that uses ingredients from your own blood to regenerate your skin and to
rejuvenate collagen, resulting in vibrant, fresh younger looking skin. These ingredients reside within the
fraction of blood named “Platelet Rich Plasma” (PRP). HPL is enriched with platelets, stem cells and growth
factors. Once injected into your skin, these substances will accelerate the normal healing process via new
collagen formation at the injected area. Because plasma (autologous) is used, there is no danger of disease
transmission, anaphylaxis or neoplasia.
Platelet Rich Plasma (PRP) with HPL injections are ‘bioactive’ stimulators NOT a filler and it will increase
collagen providing a gradual increase in skin thickness. Visible results appear after the first treatment session.
Platelet Rich Plasma (PRP) with HPL injections are effective for treating:
The eye area
Fine lines and wrinkles
Improvement in skins tone and texture
Full face rejuvenation
Décolletage
Dull dry skin
Crepey neck
Back of hands
PRP 2x is a new cutting edge technique which is ten times more efficient than regular PRP as it uses PRP
Lysate. This new technique held us to extract and target the platlet cytoplasm directly hence helping to jumpstart neo collagen genesis and the healing process.
36
Unifying Theory of Beauty
Dr Steven Dayan MD
Board Certified Facial Plastic Surgeon
Clinical Assistant Professor
University of Illinois
&
Adjunct Professor
DePaul University
USA
The importance that beauty and attraction plays to the survival and the success of the human race has
evolutionary significance. Our brains are pre-wired to sense beauty and in the over 35 million years humans
have inhabited the earth it is only in the 1% that we as a civilized species have begun to adorn, fear and dissect
the power that beauty and attraction have on our culture. This talk will go into depth about human nature,
subconscious evaluations of what we all are attracted to and why self-confidence gained is more impacting
and influential than the physical. Methods of accentuating our most endearing assets using modern day
treatments within the context of a subliminal strategy will be reviewed. Additionally, examples of how the
science of beauty can be translated and used in modern business marketing strategies in an ethical and
effective manner will be discussed. Expect to leave with a better understanding of the science of beauty,
human nature and how to use medical interventions to tease the subconscious mind.
37
A New Conceptual Approach to
Anti-Aging and Disease Prevention
Prof Dr med Fred Fändrich FRCS
Director
Clinic of Applied Cellular Medicine
University SH, Kiel Campus
Germany
Director
ff-IMT Centre
Kuala Lumpur, Malaysia
Aging is defined as the progressive accumulation of damage over time, leading to disturbed function on the
cellular, tissue and organ level and eventually to disease and death. Beyond this, aging involves a couple of
essential regulatory networks which - under normal circumstances - protect our body integrity. These include
the interaction of endogenous factors, comprising hormones, gut microbes, immune and stem cells. These
contributors coordinate important organ and tissue specific check-points which determine whether a certain
tissue compartment will be damaged or regenerated. On top of this, exogenous factors, such as nutrients,
heavy metals, sun exposure, and cigarette smoking impact on the complexity of tissue regeneration versus
decay.
In order to sustain health and physiological metabolism as well as immune and stem cell functions, it is
imperative to understand how all these different parameters influence either cellular senescence or
rejuvenation.
One central core trigger of aging, which has been put into focus of various scientific approaches to get a
closer understanding of declining body functions, is chronic inflammation. Inflammation is a natural process
to protect body integrity from physical damage (burns, wounds), or infections (viral, fungal, bacteria), as
these threats uniformly activating our immune system to release inflammatory cytokines and proteins which
are able to repair tissue damage and to defeat dangerous germs, respectively. However, once these insults
are reversed, inflammation must subside. If it sustains, it will gain an ongoing smouldering inflammatory
process. Ongoing chronic inflammation can cause a broad variety of diseases, including cancer, autoimmune
diseases, neurodegeneration, and the full scope of other degenerative diseases involving vessels, heart,
muscles, organs and joints.
As a general concept, inflammation is always associated with an acidification (pH drops) in affected tissues
and/or body components. Acidification of pH <7.0 paralyses protective immune cells and inhibits tissue
regenerating stem cells. This is due to activation of a battery of default enzymes which circumvent physiologic
mitochondrial energy supply, protective apoptotic signalling, and activation of oncogenes and reduction
of oxygen supply to support normal stem cell activity. Simultaneously, exogenous intake of heavy metals,
antibiotics, hormone-treated meat and other poisoned compounds alters the physiologic content of our gut
microbiome.
38
Human beings harbor more than 3000 different germs (termed the human microbiome) in their gut system
which effectively coordinates normal gut integrity, immunity and stem cell functions. Any disturbance of our
microbiome can cause a “leaky gut syndrome“, a disconnection of the tight junctions within the gut mucosa.
A leaky gut will trigger the formation of fungal overgrowth and toxic bacteria which in turn convert normal
sugar, lipid and carbohydrates to intermediate compounds called “advanced glycated products“. These
compounds elicit a chronic inflammatory response in various body compartments. Hence, simultaneous
chronic activation of immune effector cells which relate to the inflammatory process can be observed.
Diabetes, rheumatoid arthritis, neurodegenerative diseases (M. Parkinson, Alzheimer, MS, etc), psoriasis,
asthma, and steatotic liver diseases are only a few of those clinical manifestations which pathoethologically,
are considered to be associated with a disturbance of our microbiome.
As a matter of fact, the regulation of the microbiome, including homeostasis of activating and regulatory
immune cells, hormone levels, tissue pH and mitochondrial energy supply in hypoxic and inflamed body
compartments (e.g. skin, brain, muscles, visceral fat and liver) represent essential targets of a holistic
treatment strategy which aims at preventing and restoring dysbalanced regulatory networks of our body. We
have developed new methodological concepts to combine effective microorganisms, pH-regulatory infusion
protocols and cellular immune therapy to either prevent or to reverse those detrimental mechanisms which
must be considered to substantially accelerate aging.
This lecture will outline the pathophysilogical principles of contributing aging factors and how these can be
reversed or regulated appropriately.
39
Hormones and their Relationship with Cancer
Dr Michael Elstein
General Medical Practitioner
Eternal Health Medical Centre
Sydney, Australia
Are bio-identical hormones entirely safe or relatively safer than conventional hormone replacement therapy?
Can exogenous oestradiol increase or decrease breast cancer risk and what is the nature of this relationship?
Is oestriol, the so-called weaker oestriol, really harmless?
Is natural, ‘body-identical’ or ‘bio-identical’ progesterone, the optimal form of progesterone replacement in
terms of cardiovascular effects, blood pressure, venous thrombo-embolic events, stroke and even breast
cancer risk, contrary to synthetic progestogens and particularly medroxyprogesterone acetate, which appear
to be mitogenic on breast cells, or does progesterone promote the development of breast cancer, once
progesterone serum levels have reached the threshold for endometrial protection? What is the relationship
between progesterone and progesterone receptor A, B and C status with regard to the development of breast
cancer?
In some cancers growth hormone receptor inhibition decreases cancer growth and metastasis. Recent
evidence shows that Elevated GH/IGF-I promotes mammary tumours in high-fat, but not low-fat, fed mice.
Growth hormone’s relationship with cancer will be critically evaluated.
1,25-Dihydroxyvitamin D3 suppresses telomerase expression and human cancer growth through
microRNA-498 but is this true for all cancers and can 1,25-Dihydroxyvitamin D3 actually stimulate cancer
growth? What is the effect of vitamin D3 supplementation on the expression of 1,25-Dihydroxyvitamin D3?
Testosterone’s relationship with prostate and breast cancer in women, as well as thyroid hormone including
T4 and T3, melatonin, DHEA and cortisol’s association with cancer will be presented.
Nutritional and dietary strategies to offset potentially adverse effects of hormone treatment will also be
elaborated.
40
The Hormonal and Nutritional
Optimisation of Insulin Function
Dr Michael Elstein
General Medical Practitioner
Eternal Health Medical Centre
Sydney, Australia
Does obesity lead to insulin resistance or is it visa versa? Ageing, sometimes but not always linked with
obesity, is associated with an increased risk of developing insulin resistance. A decline in glucose tolerance
begins in the third decade and continues into old age. However for the survivors and thrivers studies on
centenarians correlate human longevity with a low degree of insulin resistance.
Growth hormone administration to reverse age-related decline in the production of this hormone has been
widely touted as an anti-ageing strategy.
Ames dwarf mice characterized by growth hormone, prolactin and thyroid-stimulating hormone deficiency live
40-60 % longer than their normal controls. Most importantly, these animals show hypersensitivity to injected
insulin, have low fasting insulin and glucose levels, high serum adiponectin, and overall are healthier as they
age, revealing similar characteristics as the one observed in centenarians. In these mice heightened insulin
sensitivity is abrogated by the administration of growth hormone.
Not all the evidence indicates that improved insulin action is a universally panacea for ageing. Some blockade
or suppression of the cellular signal or insulin function may be beneficial for health and ageing. For example,
it has been demonstrated that over-expression of the Klotho gene, which diminishes the activity of vitamin
D, extends the lifespan of mice but at the same time produces insulin resistance. Similarly, rapamycin (the
macrolide which inhibits mTOR, the mechanistic target of rapamycin) treatment extends longevity and
suppresses rather than increases insulin sensitivity and glucose tolerance, indicating that suppression of
insulin function can also be beneficial at some stages of life for healthy ageing.
This presentation will attempt to resolve insulin’s complex and seemingly contradictory effects on cellular
ageing by dissecting how hormonal action including that of growth hormone, thyroid hormones; T4 and T3,
vitamin D, oestrogen, progesterone, melatonin, DHEA and testosterone for both sexes, as well as essential
nutrients such as iodine, zinc, magnesium, B vitamins and alpha-lipoic acid, impact insulin function.
41
Key Nutrients to Support Stem Cell Therapy
Dr Karl Kamal
Director
Wellness Centre
Napier and Auckland
New Zealand
Stem Cell Therapy is becoming increasingly prevalent for a growing range of degenerative conditions.
The addition of specific nutrients improves the outcome of stem cell therapy by affecting appropriate growth
factors.
Integrative Management of Thyroid Optimization
and Case Studies
Dr Karl Kamal
Director
Wellness Centre
Napier and Auckland
New Zealand
The thyroid function is vulnerable at various points of the functional matrix. Thyroid function will be impacted
by diet, toxic exposures, oxidative stress, gastro-intestinal dysfunction, advancing age and stress.
Correcting these underlying imbalances will optimize cellular signaling and thyroid function.
The Role of Nitric Oxide in Cardiac and Vascular
Health including Erectile Dysfunction
Dr Karl Kamal
Director
Wellness Centre
Napier and Auckland
New Zealand
NO has potent endogenous effects including vasodilatory, antiplatelet, antioxidant and anti-proliferative
actions.
Through various mechanisms NO plays a key role in management of cardio-metabolic and vascular health
with multiple clinical applications.
42
Nutrition and Wellness: is there a Connection?
Puan Mary Easaw
BSc Dietetics & Nutrition, (University of Madras, Chennai, India)
Professional Diploma Cardiovascular Thoracic Sciences (Liverpool John Moores
University - United Kingdom), MSc Advanced Health Care (Liverpool John Moores
University - United Kingdom)
Chief Dietitian
National Heart Institute
Kuala Lumpur, Malaysia
Nutrition is the intake of food, considered in relation to the body’s dietary needs. Good nutrition - an
adequate, well balanced diet combined with regular physical activity - is a cornerstone of good health. Poor
nutrition can lead to reduced immunity, increased susceptibility to disease, impaired physical and mental
development, and reduced productivity. (WHO Fact Sheet 2012)
Wellness is described as a philosophy of life and personal hygiene that views health as not merely the
absence of illness but the fullest realization of one’s physical and mental potential, as achieved through
positive attitudes, fitness training, a diet low in fat and high in fiber, and the avoidance of unhealthful practices
such as smoking, drug and alcohol abuse, overeating. (Medical Dictionary for the Health Professions and
Nursing © Farlex 2012)
In the recent years nutrition and wellness have made impact in the life of consumers. Consumers are making
decision on well informed choices on their food related to wellness and lifestyle. A good example is the
emergence of functional foods, probiotics, and antioxidant in nutrition and the combination of mainstream
medical therapies such as complementary and alternative medicine in wellness. The emphasis is on holistic
approach of integrating nutrition with wellness.
This presentation will highlight the connection with Nutrition and Wellness for good health.
43
What is the Optimal Anti-Ageing Diet and How can it
be Implemented and Maintained on a Global Scale?
Dr Michael Elstein
General Medical Practitioner
Eternal Health Medical Centre
Sydney, Australia
The low glycaemic index and Palaeolithic diets have achieved popular appeal spurning a legion of followers
throughout the Western world. But as Professor Stephen Simpson, Academic Director of the Charles Perkins
Centre and Australian Research Council Laureate Fellow in the School of Biological Sciences at the University
of Sydney, explains, both excessive and diminished protein consumption can reduce lifespan. The former in
association with the hormones leptin, insulin and IGF-1 can switch on TOR (target of rapamycin) promoting
protein synthesis, lipogenesis, cell proliferation, growth and reproduction, as a consequence of which
autophagy and repair are inhibited leading to an early death. Diminished protein consumption in turn can
trigger overeating to achieve the target protein intake and this can promote obesity and insulin resistance,
equally hastening an early demise.
As nations in Africa and Asia emerge from poverty and starvation adopting Western eating habits, encouraged
by strategic marketing of the food manufacturers, will lead to the same escalation in chronic diseases that
have become the scourge of the developed world. Clearly there is a global imperative to eat wisely and this
presentation will provide practical guidelines for achieving this transformation.
44
Controversial Issues for Using Soy/Soy
Extracts in Hormone Dependent Cancers
Dr Joachim Fluhrer
BA Naturopathy (Wetzlar), MB BS (Sydney University)
Fellow of ACNEM (Melbourne)
Vice President and Senior Lecturer
Australian College of Nutritional and Environmental Medicine (ACNEM)
Victoria, Australia
Soy and Soy Extracts have a long history of use both in traditional diets and as a therapeutic substance.
Controversies arose starting with the longitudinal studies of Japanese Women, their dietary intake of Soy
and Phytoestrogens migrating to Hawaii, then followed by repeat studies in non-Asian women. Today,
we understand the effect of Soy and especially fermented Soy extracts much better, their affinity to the
Estrogen beta-receptor, the interaction of food and gut bacteria and their overall metabolism.
A review of the recent literature and in particular the safety data of use of Soy and Soy Products in
hormone dependent cancers will be explored.
In addition, the use of Soy Extracts in breast cancer, prostate cancer and the combination with
chemotherapy and Tamoxifen will be discussed. The use of specific Soy Extracts and the testing of
sensitivity in cancer patients will be explored.
45
My 3DEEP Experience
Sponsored by Aesthetics Marketing
Dr Mathew Jafarzadeh MD
Melbourne, Australia
Over the past decade, aesthetic professionals have witnessed an increasing demand for ablative and nonablative facial and body treatments with minimal to no downtime. Radiofrequency (RF) is one of the methods
for aesthetic treatments of skin tightening and skin rejuvenation. Radiofrequency devices have developed a
lot since the first monopolar ones, using one electrode via bipolar with 2 electrodes to more sophisticated
ones such as 3DEEP®, which uses multi source phase controlled RF. The 3DEEP® system by EndyMed
Medical, Caesarea Israel, is using 6 RF generators in order to create simultaneous electro-magnetic fields for
dermal heating. Heating the tissue to about 55°C, a temperature that was found to trigger the formation of new
collagen and elastin. My 3DEEP® EndyMed PRO system include both non-ablative tightening handpieces,
fractional skin resurfacing (FSR) and fractional microneedling handpieces.
The latest innovative application is the Intensif by EndyMed, which is a Microneedle Skin Remodelling
handpiece, designed to treat acne scars, deep wrinkles, dilated pores, stretch marks and other conditions
requiring deep dermal coagulation and heating.
The Intensif handpiece utilizes an array of 25 micro-diameter needles, tapered and gold plated, to safely and
effectively deliver focused RF energy deep into the dermis, providing a revolutionary collagen remodelling
solution, with minimal discomfort and downtime. Using a penetration depth of 0-3.5 mm (increment of 0.1
mm) into the skin, the RF energy is delivered directly into the deep dermis. Due to impedance differences
between the epidermis and dermis, the energy is delivered to the dermis with no significant effect on the
epidermis. The effect, in the shape of coagulated columns in the dermis, forces the body to replace the
affected tissue with a younger, healthier tissue.
My 3DEEP® experience as a doctor include Intensif microneedling treatments and Fractional skin resurfacing
using FSR handpiece. I perform 3 to 5 sessions for my patients once a month for noticeable results of
improvement in skin texture and acne scaring. On one hand, the system is safe and easy to use; on the other,
the treatments are comfortable and with short downtime to my patients. I find the 3DEEP® technology a safe
and effective RF solution for my patients.
46
Rethinking Fillers and Neurotoxins
Dr Steven Dayan MD
Board Certified Facial Plastic Surgeon
Clinical Assistant Professor
University of Illinois
&
Adjunct Professor
DePaul University
USA
Understanding the subtleties of beauty through the evolutionary lens in which it was shaped is paramount to
successful patient treatment. Treatment strategies using blunt tip cannulas, thinned out fillers that emphasizes
the subliminal forces behind both female and male beauty will be outlined. This unique method of treatment
can be done in minutes with immediate results, minimal discomfort and virtually no downtime. Additionally
branding marketing and delivering the message to your patients is an essential step to avoiding the pursuing
tsunami of commoditization.
47
Anti-Aging Inside-out with LASER Therapy
in Combination with Various Aesthetic Treatments
Sponsored by MF3
Dr Philip Choy Siu Lung
President
Hong Kong Academy of Naturopathy
Hong Kong
The Anti-aging industry has expanded over the years with many new ways to combat aging and its side
effects. Treatments today are purposed to be painless, effective and without side effects.
Photobiomodulation via blood irradiation (LBI) is one such treatment. Besides using Low Level Laser Therapy
on specific localized area of skin surfaces to treat various skin disorders such as wrinkles, acne scars,
hypertrophic scars and healing of burns, Laser blood irradiation can be used to induce and activate a myriad
of anti-aging effects internally.
This session is focused on Anti-aging and aesthetics, and to explore the use of laser therapy as an important
adjuvant to enhance existing aesthetic treatments to achieve better efficacy outcome.
Conclusion
Laser blood irradiation is one of the most fascinating versions of LLLT as it has the potential to activate a wide
range of anti-aging effects in addition to external aesthetic treatments.
48
Regenne Nose Line - Why and How to Build High
Bridge and Raise the Nose tip using PDO Thread?
Sponsored by GTG Wellness
Dr Kuljit Singh
Medical Director
Consultant Aesthetic Physician
Damansara Height Wellness Clinique
Kuala Lumpur, Malaysia
Regenne Nose Line is revolutionary PDO threads with bi directional barbs (cogs) loaded on the blunt tip
cannula. It doesn’t involve much pain, thanks to specialized cannula during the procedure. This PDO thread
is quite thick (USP1-0) enough to scaffold the hooked or sunken nose line. Bi-directional barbs enables to not
move or spread the thread inserted.
L-Carnitine Meso-lipo Injectables
for Face and Body Contouring by Allure Solution
Sponsored by GTG Wellness
Dr Kuljit Singh
Medical Director
Consultant Aesthetic Physician
Damansara Height Wellness Clinique
Kuala Lumpur, Malaysia
Allure solution consists of amino acids, vitamins, and plants extracts which are absolutely safe for the human
body. L-Carnitine plays the main role to increase metabolism to induce burned up of the fat deposits selectively
leaving the muscles intact and discharges the lympatic wastes. The result will be seen as soon as 2 weeks.
49
Recent Advances in Hair Transplant
- Man vs Robots
Dr Ruban S Nathan
Fellow of the Royal College of Physicians FRCP (Edin)
Diplomate in American Board of Laser Med & Surgery
Consultant
Dr Nathan S Skin and Laser Centre
Director
Chief Hair Transplant Surgeon
Dr Rubans Skin and Hair Clinic
Kuala Lumpur, Malaysia
Hair transplants true forefathers were the Japanese Dermatologist Shoji Okuda and the Urologist Hajime
Tamura.
Both performed successful grafts in the 1930s, the former using 1-5 mm grafts, whilst the latter used single
grafts, commenting on the superior aesthetics.
Sadly lost to history, when New York Dermatologist Orentreich took up the reigns in 1952 and subsequently
founded modern hair transplantation surgery using 4mm punch grafts resulting in the unfortunate ‘dolls hair’
plugs that gave the procedure a sullied reputation for decades.
It wasn’t until 1984 when the pathologist John Headington defined the anatomical follicular unit as occurring
naturally in one to four hair units, that dermatologists began to harvest and replant with the goal of maintaining
what nature had intended. Thus, it was in October 21, 1988, that the first single hair unit transplantation was
performed by Bobby Limmer, from an elliptical donor strip, followed by stereo microscopic dissection of the
individual grafts, then creating micro tunnels for the reinsertion of the prepared grafts in the recipient area.
Mario Marzola refined the donor scar by introducing the Trichophytic closure technique.
In 1988 - Masumi Inaba - extracted individual follicles with a single 1mm bore needle, which paved the way for
Rassman and Bernstein’s seminal paper on Follicular Unit extraction, published in 2002.
Numerous device and even Robot manufacturers have been actively marketing this technique, encouraging
fast track training for Hair transplant Surgeon “wannabes”, putting less emphasis on what remains a manual
manipulation and reinsertion technique. Ultimately advantageous to the surgeon, but of zero benefit to the
patient.
Various Hair line designs have been proposed and published in the International Hair Forums of the ISHRS
(founded by Dr Dow B Stough, in 1994), giving now extremely natural hair lines, whilst the use of tumescent
anaesthesia as defined by Dr Klein, has allowed this procedure to be performed safely with negligible bleeding.
50
Facial Anti-Aging and Firming. Korean V Lift.
How it is Compared to Radiofrequency and HIFU?
Dr Denny C Y Tang
MBBS (HK), FRACGP, MRCGP, FHKCFP, DCH (London)
DOM (CUHK), Dip Derm (Glasgow), DPD (Cardiff)
Quality Healthcare Aesthetic & Laser Centre
Hong Kong
As human beings gaining longer and longer life for the past 20 years, the need to maintain youthful look
has been increasing in demand. The history of RF in facial skin firming has been on the market for 20
years. With a recent advent of HIFU technique and the appearance of Korean-style Threadlift, the market
has never been so hot in facial skin firming. With so much offer, customers and doctors alike are facing
choices regarding which technique to choose from, investment decision of an instrument, effectiveness
and downtime. This presentation is to clarify some disclarity especially to the clinician, with respect to
the following aspects.
Unclear
1.Comparison of efficacy of Korean Thread Lift to RF and HIFU.
2.Types of absorbable ThreadLift threads. There are many types of threads (materials, thickness,
brands) available on the market of different pricing. Are there differences between them?
3.There are several techniques used for Koran-style threadLift (endotine, V-lift, Esh Lift, Fine thread
lift). Are there differences between these techniques at the final result of the procedure?
Apart from a review of recent medical journal articles about the above, there will be sharing of personal
and peer experience about the above 3 types of firming procedures.
It is hoped that after the presentation, the clinician attendees will:
1.Have a clear summary and take-home messages about choices of materials and techniques
regarding the threadLift procedure.
2.Proper and accurate selection of treatment (ThreadLift, RF or HIFU) for firming for appropriate
clients.
51
Maximizing Systemic Healing with LASER
Therapy to Enhance the Treatment
of Various Chronic Dysfunctions
Sponsored by MF3
Dr Philip Choy Siu Lung
President
Hong Kong Academy of Naturopathy
Hong Kong
The onslaughts of chronic diseases in modern times have reached a global proportion. Conditions such as
Coronary Heart diseases, Stroke, Hypertension, Hyperlipidemia, and Diabetes Mellitus has a negative impact
on the lives of patients around the world.
Fortunately, we have myriads of modalities nowadays to combat these illnesses. These modalities include
a wide array of programs such as detoxification, hormonal rebalancing and core therapies for the various
conditions.
This session is to explore the use of laser therapy as an important adjuvant to enhance the existing modalities
and treatments, and achieve better efficacy outcome.
Photobiomodulation, or better known as Low Level Laser Therapy (LLLT) is steadily moving into mainstream
medical practice.
Discovered in 1960’s, the efficacy and applications of LLLT has been widely published in peer-reviewed
studies. One of the primary use of LLLT is the restoration of the various systemic conditions of patients through
a process called blood irradiation, which improve blood microcirculation that helps to activate system-wide
healing mechanisms to further affect multiple downstream cascading effects towards better achievement of
homeostasis and delivery of the medications of the therapies.
Conclusion
Laser therapy is a powerful force and has a myriad of positive effects. Through LLLT blood irradiation, it has
the potential to activate a wide range of systemic level effects that are critical in assisting existing modalities
to achieve faster and better clinical outcome.
52
The Aging Heart
Dato Dr Tamil Selvan Muthusamy
Consultant Interventional Cardiologist
Damansara Specialist Hospital
Kuala Lumpur, Malaysia
Cardiovascular mortality increases with age. Coronary disease, heart failure, arrhythmias and stroke incidences
increase with age.
There are physiological changes that an aging heart undergoes, which may be beneficial initially but
detrimental in long term.
It is important to understand the physiological changes in an aging heart to appreciate pathological
manifestations of disease.
This lecture will include a brief account of physiological changes that occurs in the myocardium both at
macroscopic and microscopic levels. The myocardial adaption of an aging heart will be examined.
The lecture will also cover the neurological aspect of an aging heart. The communication between the brain
and the heart will be discussed.
Vascular changes that takes place and its effect in an aging heart will be explored. Differences in the vascular
structure of young and old will be touched upon. Hormonal changes and the effect on an aging heart will be
discussed.
Scientific evidence to maintain a “young heart” will be debated.
The lecture overall will be an introduction to the progress made over the last few decades in the understanding
of an aging heart.
53
What should we say to Patients with Symptoms
Unexplained by Disease?
- Functional Medicine
Sponsored by Gnosis Laboratories (M) Sdn Bhd
Dr Kuljit Singh
Medical Director
Consultant Aesthetic Physician
Damansara Height Wellness Clinique
Kuala Lumpur, Malaysia
It is almost a daily occurrence for primary care doctors to encounter patients whose symptoms are probably
not due to a discernible causes. The challenge for medicine in the 21st century will be more toward a thorough
understanding of physiological mechanisms that underlie disease rather than simply labeling later-stage
effects with the name of diseases. Functional Medicine is a dynamic approach to accurately identify the
hidden causes of patient symptoms. Rather than assessing pathology conditions, Functional Medicine Testing
assesses genetic predisposition, functional reserve, metabolic capacity, early tissue injury, etc.
Packages available:
• Comprehensive Metabolic Profile
• Adrenocortex Stress Profile
• Nutrient and Toxic Element Analysis
• Antioxidant and Vitamins Analysis
• Female and Male Hormone Profile
• Amino Acid Analysis
• Acute and Chronic Food Allergy Profile
• Glutein Sensitivity Analysis
Benefit to patient:
- It can help patient to achieve optimal health, so patient will have better and quality life instead of
disease stricken life.
- Instead of taking supplements / hormone therapy randomly and based on feel good effect, a customize
supplement / hormone therapy can be formulated for targeted outcome.
- It can help to reveal the hidden cause of patient’s unexplained tiredness, body ache and etc.
54
Introduction of DNA Profiling for Healthy Aging
Sponsored by Beacon Hospital Group of Companies
Dr Rajbans Singh MBBS, MRCP, Dip. Geriatric Med
Consultant Physician and Geriatrician
Healthy Ageing Specialist
Kuala Lumpur, Malaysia
Every one of us is born unique and there isn’t a one-size-fits-all solution when it comes to healthcare.
Personalised wellness medicine is the future of healthcare and it can be practised now through DNA Profiling!
DNA Profiling is based on the science of Nutrigenomics, the branch of science which studies the relationship
between nutrition and genetics. It focuses mainly on those genetic variants, which were found in research that
have significant impact on the body’s metabolic pathways, meaning that they participate in the absorption
and metabolism of nutrients, immunity and inflammation, detoxifying mechanisms, and tendency toward
some modern diseases, such as cardiovascular disease and type II diabetes. DNA Profiling synchronises
individual genetic profile with diet and lifestyle program, combined with other factors including personal health
condition, it provides the knowledge to prevent chronic diseases and reduce the chances of developing
serious health conditions towards total wellness and healthy ageing.
55
Diet and Exercise for Obesity
by Optimizing Hormonal System
(Leptin, Insulin, Growth Hormone, Testosterone)
Dr Tanjung Subrata MD, MRepro, ABAARM
Chief of Research and Education
VICTUS Life Longevity Institute
Bali, Indonesia
Special Advisor
Singapore Medical Fitness Management (SMFM)
Singapore
Obesity is one of the greatest health problems in the world currently, WHO said there are more than one billion
overweight and 300 million obese adults in the world. Obesity has passed cigarette smoking as the number
one preventable killer because it’s connected with a host of medical problems ranging from heart disease and
high blood pressure to diabetes, arthritis, cancer, etc.
In addressing the problem of obesity it is not only how much you lose weight, but that it is far more important
to maintain the weight loss permanently. In one study, they proved 98% of people who lose weight on a diet
gain it all back within five years and 90% of those gain back more weight than they lost.
Many studies proves that diet and exercise are the methods to manage obesity, but how to design a diet
and exercise model becomes most effective to overcome obesity. Obesity is not solely a problem of excess
calories, but also involves complex hormonal problems. A lot of hormones are involved in obesity problems;
leptin, insulin, growth hormone, testosterone, cortisol, etc. How to optimize your hormonal system by losing
weight and maintaining it, is the key.
Hormones have powerful interactions with fat cells and have a major influence on the weight. These
hormonal changes exert profound effects on metabolism and fat distribution, cortisol and insulin promote fat
accumulation while testosterone and growth hormone exert opposite effects. Designing a diet protocol for
obesity, not only about how much calories are contained in the diet, far more than that, is how to design a
diet protocol to support our hormonal system. A diet protocol which can alleviate leptin resistance and insulin
resistance, will fix the root cause of obesity problems.
Exercise is like medicine, they have a dose (intensity), frequency, time and type. Each method has different
effects based on their energy system, which will affect the hormonal system. Even the same exercise protocol
(same weight, same intensity and the same type), but when we do it at different times will get different
results on the hormonal system. Based on energy system, we can design an exercise protocol to support our
hormonal system for optimizing the fat loss program.
56
Health and Fitness
Major General Dato Pahlawan Dr R Mohanadas (Rtd)
Deputy Chairman, Board of Governors
Cyberjaya University College of Medicine
Board Member
Asia Metropolitan University
Selangor, Malaysia
Malaysians are ageing. In the year 1990, those of the age of 60 and above accounted for 5.7% of our population.
In the year 2000, it rose to 6.3%, and this figure is expected to rise to 9.8% by 2020. Maintaining independent
living as we age is essential for a dignified quality of life in later years. Generally senior citizens get frustrated
and depressed when they find themselves unable to perform the activities that they normally could on their
own. Health literacy is essential in maintaining a healthy life. Undergoing periodic medical examinations with
reference to early detection of risk factors for the different phases in life, understanding the results of the
examinations and modifying lifestyle to cope with those stresses is important to successful ageing. Simple
indices like knowing the heart rate, blood pressure, blood sugar, cholesterol, uric acid and body mass index
as against desirable levels help.
Physical activities as we age is the best low cost recipe to healthy ageing. The body needs to keep moving,
in any form, walking, gardening, cleaning up the home and just running errands is important. Effort must
also be made to participate in structured regular exercises. There is overwhelming evidence that exercising
regularly reduces morbidity and mortality from all causes. Regular exercise must be focussed on four
areas: a. cardiovascular fitness (aerobic exercises like brisk walking, jogging, swimming, climbing stairs)
b. maintaining muscle strength (minimum weight lifts and working against resistance, keeps you stronger
and slows down muscle wasting) c. balancing exercises (like standing on one leg, helps prevent falls) and
d. flexibility (stretching exercises of the muscles and ligaments).
Having the advantage of the knowledge of one’s own health profile, and the benefits of the various forms
of exercises, its intensity and frequency, adds years to one’s life. There is sufficient evidence to show that
even moderate exercises, as long as it is regular, helps in the management of obesity, arthritis, hypertension,
diabetes mellitus and cardio vascular diseases. Let’s all age with minimum disability.
Key words: health literacy, periodic medical examinations, physical activity, structured exercises
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Stay Young with Exercise
Prof Rabindarjeet Singh PhD, FNSM
Lifestyle Science Cluster
Advanced Medical and Dental Institute
Universiti Sains Malaysia
Bertam, 13200 Kepala Batas
Penang, Malaysia
Aging is a natural continuum of biological processes characterised by progressive adaptations, which can be
influenced by both genetic and physiological factors. Lifestyle of modern industrialised societies, although
thought to be ”fast-paced”, is often associated with poor eating habits and sedentarism, which in the long
term can lead to frailty in the elderly. The decline in the various physiological capacities in the elderly as a
result of the aging process has been regarded as an unavoidable part of growing old. However, there is now
growing evidence that exercise has a positive influence on increasing healthy function and decreasing the
impact of diseases common in the elderly, thus improving the quality of life in the older adults. It is important
to recognize that ‘exercise’ is as broad a term as ‘medicine’ and that different kinds of exercise have different
effects. This presentation will summarise the benefits of regular exercise on longevity, present some current
theories regarding potential mechanisms in staying young while chronologically aging. A number of studies
have shown that maintaining a minimum quantity and quality of exercise decreases the risk of death, prevents
the development of certain cancers, lowers the risk of osteoporosis and increases longevity.
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Myofascial Dry Needling for
Musculoskeletal Pain
Dr Tanjung Subrata MD, MRepro, ABAARM
Chief of Research and Education
VICTUS Life Longevity Institute
Bali, Indonesia
Special Advisor
Singapore Medical Fitness Management (SMFM)
Singapore
Myofascial pain is a common form of pain that arises from muscles or related fascia and is usually associated
with myofascial trigger points (MTrP). An MTrP is a highly localized, hyperirritable spot in a palpable, taut
band of skeletal muscle fibers. When an MTrP is stimulated, 2 important clinical phenomena can be elicited:
referred pain and a local twitch response.
Epidemiologic studies from the United States have shown that MTrPs were the primary source of pain in
30% to 85% of patients presenting in a primary care setting or pain clinic because of pain. MTrPs were the
primary source of pain in 74% of 96 patients with musculoskeletal pain who were seen by a neurologist in a
community pain medical center, and in 85% of 283 patients consecutively admitted to a comprehensive pain
center. Therefore, MTrP pain constitutes a substantial burden for both individual patients and for society as a
whole. Despite this, there is evidence that MTrPs that cause musculoskeletal pain often go undiagnosed by
both physicians and physical therapists, which leads to chronic conditions.
Numerous non-invasive methods - such as stretching, massage, ischemic compression, laser therapy, heat,
acupressure, ultrasound, transcutaneous electrical nerve stimulation, biofeedback, and pharmacological
treatments - have been used to alleviate chronic myofascial pain, but no single strategy has proved to be
universally successful. Another way to treat myofascial pain is by dry needling (intramuscular stimulation,
Western acupuncture, medical acupuncture), which is a minimally invasive procedure in which an acupuncture
needle is inserted directly into an MTrP. Although an acupuncture needle is used, the therapy is based on
the traditional reasoning of Western medicine. The sites for needle insertion are located in skeletal muscles
taught in any basic anatomy course.
Different methods of dry needling, its effectiveness, and physiologic and adverse effects are discussed. Dry
needling is a treatment modality that is minimally invasive, cheap, easy to learn with appropriate training, and
carries a low risk. Its effectiveness has been confirmed in numerous studies and 2 comprehensive systematic
reviews. The deep method of dry needling has been shown to be more effective than the superficial one for
the treatment of pain associated with myofascial trigger points. However, over areas with potential risk of
significant adverse events, such as lungs and large blood vessels, we suggest using the superficial technique,
which has also been shown to be effective, albeit to a lesser extent.
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Anti-Aging: Past, Present and Future
Assoc Prof Dr Andrew Charles Gomez MBBS (Nagpur), FRCS (Edin), FRCS (Glas)
Consultant ENT Surgeon
Charles Gomez Head & Neck, Ear Nose & Throat
& Facial Cosmetic Surgical Centre
Kuala Lumpur, Malaysia
“The quest for immortality has always been in the forefront of human mind. Civilizations throughout history
have always looked at various methods to prolong life. Advances in technology and research have ushered in
a new era of medical information that only a generation ago was unheard of. We are now able to travel to the
inner sanctuary of the body well into the amino acid structure of DNA. These discoveries mean that many of
our traditional understandings on health issues need constant revisions and updating.
The concept of aging is one such issue. The longest human lifespan recorded was that of Jeannie Calmant
who lived to the age of 122 years. It was formerly thought that our life expectancy is predestined. Anti-aging
physicians using hormonal replacement therapies, vitamins, minerals, amino-acids and essential fatty acids
have now challenged this concept with recent advances showing that nutrition, biochemistry, cellular biology,
physiology and exercise can prolong life.
Anti-aging technologies include (1) stem cells which are self-renewing, i.e., primate cells that can develop into
functional and differentiated cells; (2) cloning. In 1997, Dr Ian Wilmut, in Roselyn Institute unveiled Dolly the
sheep; (3) nano-technology; (4) artificial organs. Dr Willem Kloff, in the mid-1950’s invented the kidney dialysis
machine. He then developed the artificial heart and his team are now working to produce mechanical body
parts which would be able to replace worn-out or damaged human organs; (5) nerve impulse continuity. The
brain communicates to the rest of the body. In spinal cord injuries, this communication is prevented. Starting
in 2002, an electronic stimulator implanted in a person who was paralysed in all his four limbs regained
walking ability. Latest research shows that nerve cells taken from the nasal cavity can be used to regenerate
spinal cord cells; (6) genetic engineering also called genetic modification is a direct manipulation of the
organism’s genome using biotechnology. New DNA can be inserted into the host genome by first isolating
and copying the gene material of interest using molecular cloning methods to generate a DNA sequence or
by synthesizing the DNA which can then be inserted into these organisms. The genes can be used to either
accentuate or remove the offending nucleus.
Cosmetic surgery constitutes the fastest growing set of surgical procedures in the world. Continuing
advancement in technology and the tremendous increase in life-enhancing procedures have made such
procedures more affordable and safe, without necessarily using invasive methods. As positive aging has
improved the quality of life, more and more people are giving their appearance top priority.”
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The Pain Truth
Dr Steven Dayan MD
Board Certified Facial Plastic Surgeon
Clinical Assistant Professor
University of Illinois
&
Adjunct Professor
DePaul University
USA
Let’s be frank, cosmetic medicine is a largely subjective field. As important as it is to achieve improvements
in wrinkles, lines and folds, the resulting psyche and elevation in self-esteem is also important – maybe
more so. It seems likely that the patients’ perceived outcomes from a cosmetic treatment greatly affect
the level of satisfaction the patient has with the treatment as well influencing their opinion of the provider.
And essential to achieving high patient satisfaction is to link a positive outcome with a positive experience
in an environment with minimal anxiety.
What have failed to properly address as an aesthetic community is the fear of pain. As an academic
field we have likely devalued the significance of this issue. Perhaps, because, “To be beautiful is painful”
- an oft heard maxim from women in the clinic who seem to honor a tradition where being beautiful
takes a modicum of discomfort. Pain may be viewed as a punishment or a deserved recourse, a notion
reminiscent of medieval lore. Or maybe the acceptance is an expected derivative from a field of medicine
traditionally dominated by the lesser sensitive gender delivering treatments to the more sensitive gender,
regardless, the fear of pain from elective procedures is likely a much greater barrier to patients wanting
and getting a treatment then imagined. One of the great difficulties in understanding pain and its influence
on cosmetic procedure is that the perception of pain varies so greatly between individuals. And besides
physiological variability’s in pain perception there is a large chasm in pain perception rooted in our
cultural, ethnicity, gender and even chronotypes. Nevertheless, still today up to 31% of experienced
botulinum toxin patients indicate the fear of pain prevents them from coming in for an appointment. The
question that begs to be asked is how many potential treatment naïve cosmetic patients don’t come to
the clinic because of anxiety and the fear of pain? Today’s patients are now demanding less procedure
pain and if we can meet their demand perhaps the market of patient seeking and appreciating cosmetic
treatments will grow exponentially. Pain free/anxiety free aesthetic medicine, our next frontier.
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“You Used to Cut People?”
Dr Steven Dayan
MD
Board Certified Facial Plastic Surgeon
Clinical Assistant Professor
University of Illinois
&
Adjunct Professor
DePaul University
USA
Let’s face it the progression of medicine from Cholecystectomies to coronary bypass continues to evolve
towards less and less invasive and cosmetic plastic surgery is not immune. While in the future medical
students may shudder at the thought of their physician ancestors using knives to incise tissue we are not
yet ready to donate our scalpels to the Natural History Museum. However, it is imperative that the evolving
aesthetic physician be cognizant of the increasing demand from modern patients for minimally invasive
cosmetic treatments. Today there are many non-surgical cosmetic treatments that can greatly complement
outcomes from surgery. Understanding the benefits and limitations gained from fillers, neurotoxins and lasers
as well as how to safely and effectively implement them can result in a healthy injection of vitality for a practice.
What was once a luxury adjunct to a cosmetic practice is rapidly becoming a necessity.
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Telomere Length and Anti-Aging
Dr Denny C Y Tang
MBBS (HK), FRACGP, MRCGP, FHKCFP, DCH (London)
DOM (CUHK), Dip Derm (Glasgow), DPD (Cardiff)
Quality Healthcare Aesthetic & Laser Centre
Hong Kong
The proposed lecture will contain the following salient points:
Background
Telomeres are tandem repeats of sequences present at the end of the chromosomes that maintain chromosomal
integrity. After repeated cell division, telomeres shorten to a critical level, triggering replicative senescence or
apoptosis, which is a key determinant of cellular aging. Short telomeres also contribute to genome instability
and are a hallmark of many cancers.
The Body
1.(How?) Methods of measuring telomere lengths. To date, there are several methods for estimating
telomerelength (TL) from extracted DNA samples. Southern blot is accurate but requires a large quantity
of DNA and is expensive. qPCR is cost-effective and requires a small quantity of DNA and is therefore
widely used for large-scale epidemiologic studies; however, it typically requires triplicates. We describe
a novel multiplexed probe-based non-PCR method for TL measurement.
2.(What?) Utilizing Telomere lengths in different types of cells in the relationships of these lengths to the
possibilities of predicting various kinds of diseases and, or general ageing status, and how accurate the
prediction of biological age is.
3.(What?) With the above information, how we shall go further regarding the possibility of reversing the
shortening of telomere length, on the road to anti-ageing.
Conclusion
Measuring Telomere Length is a valid method for the practice of anti-ageing medicine.
63
Probiotics and Gut Health
Dr Sunaryati Sudigdo Adi
Department of Microbiology and Parasitology
Faculty of Medicine
Padjadjaran University
Bandung, Indonesia
Probiotics are living microorganisms that are able to reach the gastointestinal tract and alter its microfloral
composition, producing beneficial health effects when consumed in adequate amounts. Recent clinical trials
have evaluated the clinical effectiveness of probiotics in the treatment and prevention of a wide range of acute
and chronic gastrointestinal diseases, and also non gastrointestinal diseases. The gastointestinal microbiota
plays an important role in host health due to its involvement in nutritional, immunologic and physiological
functions. Microbial imbalances have been associated with enhanced risk of specific diseases. The mechanism
of action include the inhibition of pathogen growth by competition for nutritional sources and adhesion sites,
secretion of antimicrobial substances, toxin inactivation. The well-characterized immunomodulatory potential
of specific probiotics strains, beyond the effect on the composition of the microbiota, has been used as
innovative tools to alleviate intestinal inflammation, normalize gut mucosal dysfunction, and down regulate
hypersensitivity reactions. Clinical efficacy of specific probiotics strains has been demonstrated in, rotavirus’s
diarrhea, antibiotic associated diarrhea, irritable bowel syndrome and food allergies. Further, recent clinical
and nutritional studies have encountered the function of specific strains in energy metabolism and thereby
have opened up new angles on their exploitation.
Keywords: probiotics, gut micobiota, health, diseases
64
Save your Heart with ECP
Prof Dr Hj Mohd Ebrahim Sulaiman
MBBS, DTM&H
Diploma Ultrasound Canada
FAAFP, APCT-ACAM, CMT
Integrative (complementary & alternative) medicine
Klinik Ebrahim & Surgery
Kuala Lumpur, Malaysia
What is ECP (External Counterpulsation)? Simply put, it is the use of a computerised and synchronised
medical device to pump the blood sequentially from the lower body pushing towards the heart in order to
open up the heart arteries during the heart’s resting period. The machine takes over the function of the heart
and gives rest to the heart muscles with more oxygen supply for about one to two hours during the procedure.
ECP was discovered in the 1950s. Various research has since been conducted on ECP, with results obtained
by reputable Universities has been documented and published in various medical publications. ECP was
approved by the United States Food and Drugs Administration in 1995.
This unique technique is safe, cheap, painless noninvasive. It has the potential to save thousands of lives
and billions of dollars. Patients who were not amenable to surgery and who require heart transplants have
undergone this therapy and are now enjoying a better quality of life. ECP therapy also offers many side
benefits - it can help to rehabilitate stroke patients, cure gangrene on the foot, and improve the lives of
patients with circulatory disorders.
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