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Anatomy and Physiology
Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings
Overview of Anatomy and Physiology
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Anatomy – the study of the structure of body parts
and their relationships to one another
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Gross or macroscopic
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Microscopic
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Developmental
Physiology – the study of the function of the
body’s structural machinery
Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings
Gross Anatomy
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Regional – all structures in one part of the body
(such as the abdomen or leg)
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Systemic – gross anatomy of the body studied by
system
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Surface – study of internal structures as they relate
to the overlying skin
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Microscopic Anatomy
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Cytology – study of the cell
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Histology – study of tissues
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Developmental Anatomy
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Traces structural changes throughout life
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Embryology – study of developmental changes of
the body before birth
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Specialized Branches of Anatomy
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Pathological anatomy – study of structural changes
caused by disease
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Radiographic anatomy – study of internal
structures visualized by specialized scanning
procedures such as X-ray, MRI, and CT scans
ƒ
Molecular biology – study of anatomical structures
at a subcellular level
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Physiology
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Considers the operation of specific organ systems
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Renal – kidney function
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Neurophysiology – workings of the nervous
system
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Cardiovascular – operation of the heart and blood
vessels
Focuses on the functions of the body, often at the
cellular or molecular level
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Physiology
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Understanding physiology also requires a
knowledge of physics, which explains
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electrical currents
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blood pressure
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the way muscle uses bone for movement
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Principle of Complementarity
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Function always reflects structure
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What a structure can do depends on its specific
form
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Levels of Structural Organization
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Chemical – atoms combined to form molecules
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Cellular – cells are made of molecules
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Tissue – consists of similar types of cells
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Organ – made up of different types of tissues
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Organ system – consists of different organs that
work closely together
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Organismal – made up of the organ systems
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Levels of Structural Organization
Smooth muscle cell
Molecules
2 Cellular level
Cells are made up of
molecules.
Atoms
1 Chemical level
Atoms combine to
form molecules.
3 Tissue level
Tissues consist of
similar types of cells.
Smooth
muscle
tissue
Heart
Cardiovascular
system
Blood
vessels
Epithelial
tissue
Smooth
muscle
tissue
Connective
tissue
4 Organ level
Organs are made up
of different types
of tissues.
Blood
vessel
(organ)
6 Organismal level
The human organism
is made up of many
organ systems.
5 Organ system level
Organ systems consist of
different organs that
work together closely.
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Figure 1.1
Integumentary System
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Forms the external body
covering
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Composed of the skin, sweat
glands, oil glands, hair, and
nails
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Protects deep tissues from
injury and synthesizes vitamin
D
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Figure 1.3a
Skeletal System
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Composed of bone, cartilage,
and ligaments
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Protects and supports body
organs
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Provides the framework for
muscles
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Site of blood cell formation
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Stores minerals
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Figure 1.3b
Muscular System
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Composed of muscles and
tendons
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Allows manipulation of the
environment, locomotion, and
facial expression
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Maintains posture
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Produces heat
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Figure 1.3c
Nervous System
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Composed of the brain, spinal
column, and nerves
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Is the fast-acting control
system of the body
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Responds to stimuli by
activating muscles and glands
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Figure 1.3d
Cardiovascular System
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Composed of the heart and
blood vessels
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The heart pumps blood
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The blood vessels transport
blood throughout the body
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Figure 1.3f
Lymphatic System
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Composed of red bone
marrow, thymus, spleen,
lymph nodes, and lymphatic
vessels
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Picks up fluid leaked from
blood vessels and returns it to
blood
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Disposes of debris in the
lymphatic stream
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Houses white blood cells
involved with immunity
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Figure 1.3g
Respiratory System
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Composed of the nasal cavity,
pharynx, trachea, bronchi, and
lungs
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Keeps blood supplied with
oxygen and removes carbon
dioxide
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Figure 1.3h
Digestive System
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Composed of the oral cavity,
esophagus, stomach, small
intestine, large intestine,
rectum, anus, and liver
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Breaks down food into
absorbable units that enter the
blood
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Eliminates indigestible
foodstuffs as feces
Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings
Figure 1.3i
Urinary System
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Composed of kidneys, ureters,
urinary bladder, and urethra
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Eliminates nitrogenous wastes
from the body
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Regulates water, electrolyte,
and pH balance of the blood
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Figure 1.3j
Male Reproductive System
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Composed of prostate gland,
penis, testes, scrotum, and
ductus deferens
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Main function is the
production of offspring
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Testes produce sperm and
male sex hormones
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Ducts and glands deliver
sperm to the female
reproductive tract
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Figure 1.3k
Female Reproductive System
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Composed of mammary glands,
ovaries, uterine tubes, uterus, and
vagina
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Main function is the production of
offspring
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Ovaries produce eggs and female
sex hormones
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Remaining structures serve as sites
for fertilization and development of
the fetus
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Mammary glands produce milk to
nourish the newborn
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Figure 1.3l
Organ Systems Interrelationships
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The integumentary system protects the body from
the external environment
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Digestive and respiratory systems, in contact with
the external environment, take in nutrients and
oxygen
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Organ Systems Interrelationships
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Nutrients and oxygen are
distributed by the blood
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Metabolic wastes are
eliminated by the urinary
and respiratory systems
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Figure 1.2
Necessary Life Functions
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Maintaining boundaries – the internal environment
remains distinct from the external environment
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Cellular level – accomplished by plasma
membranes
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Organismal level – accomplished by the skin
Movement – locomotion, propulsion (peristalsis),
and contractility
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Necessary Life Functions
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Responsiveness – ability to sense changes in the
environment and respond to them
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Digestion – breakdown of ingested foodstuffs
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Metabolism – all the chemical reactions that occur
in the body
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Excretion – removal of wastes from the body
Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings
Necessary Life Functions
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Reproduction – cellular and organismal levels
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Cellular – an original cell divides and produces two
identical daughter cells
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Organismal – sperm and egg unite to make a whole
new person
Growth – increase in size of a body part or of the
organism
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Survival Needs
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Nutrients – needed for energy and cell building
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Oxygen – necessary for metabolic reactions
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Water – provides the necessary environment for
chemical reactions
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Normal body temperature – necessary for chemical
reactions to occur at life-sustaining rates
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Atmospheric pressure – required for proper
breathing and gas exchange in the lungs
Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings
Homeostasis
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Homeostasis – ability to maintain a relatively
stable internal environment in an ever-changing
outside world
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The internal environment of the body is in a
dynamic state of equilibrium
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Chemical, thermal, and neural factors interact to
maintain homeostasis
Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings
Homeostatic Control Mechanisms
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Variables produce a change in the body
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The three interdependent components of control
mechanisms:
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Receptor – monitors the environments and
responds to changes (stimuli)
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Control center – determines the set point at which
the variable is maintained
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Effector – provides the means to respond to stimuli
Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings
Homeostatic Control Mechanisms
3 Input:
Information
sent along
afferent
pathway to
Control
center
4 Output:
Information sent
along efferent
pathway to
Receptor (sensor)
Effector
2 Change
detected
by receptor
5
1
Stimulus:
Produces
change
in variable
I mb
ala
nce
Variable (in homeostasis)
Response of
effector feeds
back to
influence
magnitude of
stimulus and
returns variable
to homeostasis
I mb
ala
nce
Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings
Figure 1.4
Negative Feedback
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In negative feedback systems, the output shuts off
the original stimulus
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Example: Regulation of room temperature
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Positive Feedback
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In positive feedback
systems, the output
enhances or
exaggerates the
original stimulus
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Example: Regulation
of blood clotting
Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings
Figure 1.6
Homeostatic Imbalance
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Disturbance of homeostasis or the body’s normal
equilibrium
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Overwhelming the usual negative feedback
mechanisms allows destructive positive feedback
mechanisms to take over
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Anatomical Position
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Body erect, feet slightly
apart, palms facing
forward, thumbs point
away from body
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Figure 1.7a
Directional Terms
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Table 1.1a
Directional Terms
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Table 1.1b
Regional Terms: Anterior View
Nasal (nose)
Frontal (forehead)
Orbital (eye)
Oral (mouth)
Buccal (cheek)
Cervical (neck)
Mental (chin)
Acromial
(point of shoulder)
Axillary (armpit)
Sternal
(breastbone)
Thoracic
(chest)
Mammary
(breast)
Abdominal
(abdomen)
Brachial (arm)
Antecubital
(front of elbow)
Antebrachial
(forearm)
Pelvic (pelvis)
Umbilical
(navel)
Carpal (wrist)
Pollex
(thumb)
Palmar
(palm)
Coxal
(hip)
Digital
(fingers)
Inguinal
(groin)
Pubic (genital region)
Femoral
(thigh)
Patellar
(anterior knee)
Fibular, or
peroneal
(side of leg)
Crural (leg)
Pedal
(foot)
Tarsal (ankle)
Digital (toes)
Hallux (great toe)
(a) Anterior
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Figure 1.7a
Regional Terms: Posterior View
Otic (ear)
Cephalic
(head)
Occipital (back of
head or base of skull)
Acromial
(point of shoulder)
Vertebral
(spinal column)
Scapular
(shoulder blade)
Brachial (arm)
Dorsum or dorsal
(back)
Olecranal
(back of elbow)
Lumbar (loin)
Sacral
(between hips)
Upper
extremity
Manus
(hand)
Gluteal (buttock)
Perineal
(region between
the anus and
external genitalia)
Femoral (thigh)
Popliteal
(back of knee)
Lower
extremity
Sural (calf)
Calcaneal (heel)
Plantar (sole)
(b) Posterior
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Figure 1.7b
Body Cavities
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Dorsal cavity protects the nervous system, and is
divided into two subdivisions
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Cranial cavity – within the skull; encases the brain
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Vertebral cavity – runs within the vertebral
column; encases the spinal cord
Ventral cavity houses the internal organs (viscera),
and is divided into two subdivisions
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Thoracic
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Abdominopelvic
Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings
Body Cavities
Cranial cavity
(contains brain)
Thoracic
cavity
(contains
heart
and lungs)
Dorsal
body
cavity
Diaphragm
Vertebral cavity
(contains spinal
cord)
Abdominal cavity
(contains digestive
viscera)
Key:
Pelvic cavity
(contains bladder,
reproductive organs,
and rectum)
Dorsal body cavity
Ventral body cavity
(a) Lateral view
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Figure 1.9a
Body Cavities
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Thoracic cavity is subdivided into two pleural
cavities, the mediastinum, and the pericardial
cavity
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Pleural cavities – each houses a lung
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Mediastinum – contains the pericardial cavity;
surrounds the remaining thoracic organs
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Pericardial cavity – encloses the heart
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Body Cavities
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The abdominopelvic cavity is separated from the
superior thoracic cavity by the dome-shaped
diaphragm
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It is composed of two subdivisions
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Abdominal cavity – contains the stomach,
intestines, spleen, liver, and other organs
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Pelvic cavity – lies within the pelvis and contains
the bladder, reproductive organs, and rectum
Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings
Body Cavities
Key:
Cranial
cavity
Dorsal body cavity
Ventral body cavity
Vertebral
cavity
Thoracic
cavity
(contains
heart
and lungs)
Superior
mediastinum
Pleural
cavity
Pericardial
cavity within
the mediastinum
Diaphragm
Abdominal cavity
(contains digestive
viscera)
Abdominopelvic
cavity
Ventral
body cavity
(thoracic
and
abdominopelvic
cavities)
Pelvic cavity
(contains bladder,
reproductive organs,
and rectum)
(b) Anterior view
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Figure 1.9b
Other Body Cavities
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Oral and digestive – mouth and cavities of the
digestive organs
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Nasal –located within and posterior to the nose
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Orbital – house the eyes
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Middle ear – contains bones (ossicles) that transmit
sound vibrations
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Synovial – joint cavities
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Other Body Cavities
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Figure 1.13
Abdominopelvic Regions
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Figure 1.11a
Organs of the Abdominopelvic Regions
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Figure 1.11b
Abdominopelvic Quadrants
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Right upper
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Left upper
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Right lower
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Left lower
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Figure 1.12
Ventral Body Cavity Membranes
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Parietal serosa lines internal body walls
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Visceral serosa covers the internal organs
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Serous fluid separates the serosae
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Serous Membrane Relationship
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Figure 1.10a
Heart Serosae
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Figure 1.10b
Body Planes
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Sagittal – divides the body into right and left parts
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Midsagittal or medial – sagittal plane that lies on
the midline
ƒ
Frontal or coronal – divides the body into anterior
and posterior parts
ƒ
Transverse or horizontal (cross section) – divides
the body into superior and inferior parts
ƒ
Oblique section – cuts made diagonally
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Body Planes
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Figure 1.8
Anatomical Variability
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Humans vary slightly in both external and internal
anatomy
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Over 90% of all anatomical structures match
textbook descriptions, but:
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Nerves or blood vessels may be somewhat out of
place
ƒ
Small muscles may be missing
Extreme anatomical variations are seldom seen
Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings