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Mycosis fungoides shows concurrent deregulation of multiple genes involved in the TNF signaling pathway: an expression profile study by Lorraine Tracey, Raquel Villuendas, Ana Maria Dotor, Inmaculada Spiteri, Pablo Ortiz, Juan F. García, Jose Luis Rodríguez Peralto, Mark Lawler, and Miguel A. Piris Blood Volume 102(3):1042-1050 August 1, 2003 ©2003 by American Society of Hematology Relevant histologic and immunophenotypical characteristics were analyzed. Lorraine Tracey et al. Blood 2003;102:1042-1050 ©2003 by American Society of Hematology Unsupervised clustering of raw and normalized MF and ID data. Lorraine Tracey et al. Blood 2003;102:1042-1050 ©2003 by American Society of Hematology Using a t statistic and an adjusted P value, 27 genes significant in the separation of MF from ID samples were identified (29 MF samples, 11 ID samples). . Lorraine Tracey et al. Blood 2003;102:1042-1050 ©2003 by American Society of Hematology Identification of MF subgroups using hierarchic clustering methods. Lorraine Tracey et al. Blood 2003;102:1042-1050 ©2003 by American Society of Hematology Genes implicated in separation of MF immunohistochemical/histologic subgroups. Lorraine Tracey et al. Blood 2003;102:1042-1050 ©2003 by American Society of Hematology TNF signaling pathway deregulation in MF tumorigenesis. Lorraine Tracey et al. Blood 2003;102:1042-1050 ©2003 by American Society of Hematology