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Mycosis fungoides shows concurrent deregulation of
multiple genes involved in the TNF signaling pathway: an
expression profile study
by Lorraine Tracey, Raquel Villuendas, Ana Maria Dotor, Inmaculada Spiteri, Pablo
Ortiz, Juan F. García, Jose Luis Rodríguez Peralto, Mark Lawler, and Miguel A. Piris
Blood
Volume 102(3):1042-1050
August 1, 2003
©2003 by American Society of Hematology
Relevant histologic and immunophenotypical characteristics were analyzed.
Lorraine Tracey et al. Blood 2003;102:1042-1050
©2003 by American Society of Hematology
Unsupervised clustering of raw and normalized MF and ID data.
Lorraine Tracey et al. Blood 2003;102:1042-1050
©2003 by American Society of Hematology
Using a t statistic and an adjusted P value, 27 genes significant in the separation of MF from ID
samples were identified (29 MF samples, 11 ID samples). .
Lorraine Tracey et al. Blood 2003;102:1042-1050
©2003 by American Society of Hematology
Identification of MF subgroups using hierarchic clustering methods.
Lorraine Tracey et al. Blood 2003;102:1042-1050
©2003 by American Society of Hematology
Genes implicated in separation of MF immunohistochemical/histologic subgroups.
Lorraine Tracey et al. Blood 2003;102:1042-1050
©2003 by American Society of Hematology
TNF signaling pathway deregulation in MF tumorigenesis.
Lorraine Tracey et al. Blood 2003;102:1042-1050
©2003 by American Society of Hematology
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