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OSTEOPOROSIS KEY POINTS Osteoporosis is the most common metabolic bone disorder resulting in low bone density. It occurs when the rate of bone resorption (osteoclast cells) exceeds the rate of bone formation (osteoblast cells) resulting in fragile bone tissue subsequent fractures. Osteopenia (precursor to osteoporosis), refers to low bone mineral density for what is expected for the person’s age and sex. Peak bone mineral density: age of 30 to 35 years. After that, bone density decreases, rapidly in postmenopausal women due to estrogen loss. Fragile, thin bone tissue is susceptible to fracture. RISK FACTORS Age 60 Postmenopausal estrogen deficiency Family Hx Thin, lean body build Hx of low calcium intake with suboptimal levels of vitamin D Hx of smoking Hx of high alcohol intake Lack of physical activity/prolonged immobility SECONDARY OSTEOPOROSIS Hyperparathyroidism. Long-term corticosteroid use (for example, asthma). Long-term immobility (for example, spinal cord injury). DIAGNOSTIC PROCEDURES AND NURSING INTERVENTIONS Radiographs of the spine and long bones reveal low bone density and fractures. Dual energy x-ray absorptiometry (DEXA) is used to screen for early changes in bone density. This painless test measures bone mineral density in the wrist, hip, and vertebral column. Serum calcium, vitamin D, phosphorus, and alkaline phosphatase levels are drawn to rule out other metabolic bone diseases (Paget’s disease or osteomalacia). ASSESSMENT Monitor for signs and symptoms. Thoracic kyphosis Reduced height (postmenopausal) Acute back pain after lifting or bending (worse with activity, relieved by rest) Restricted movement Fractures Fear of falling NANDA NURSING DIAGNOSES Impaired mobility Imbalanced nutrition: Less than body requirement Risk for falls Ineffective health maintenance NURSING INTERVENTION NURSING INTERVENTION Instruct the client and family regarding dietary calcium food sources. Provide information regarding calcium supplementation (take with food). Instruct the client of the need for adequate amounts of protein, magnesium, vitamin K, and other trace minerals needed for bone formation. Reinforce the need for exposure to vitamin D (sunlight, fortified milk). Assess the home environment for safety (remove throw rugs, adequate lighting, clear walkways). Reinforce the use of safety equipment and assistive devices. Instruct the client to avoid inclement weather (ice or slippery surfaces). Clearly mark thresholds, doorways, and steps. Prevention Teach the importance of regular, weight-bearing exercises. Introduce the importance of calcium intake to children to improve peak bone mass. Strong adult skeletons are built during childhood. COMPLICATIONS AND NURSING IMPLICATIONS Fractures are the leading complication of osteoporosis. Early recognition and treatment is essential. The nurse should review risk factors for osteoporosis and falls, assess the client’s dietary intake of calcium, reinforce daily exercise including weight-bearing activities, and ensure proper screening with a DEXA scan. TEST YOURSELF Which of the following clients is at the greatest risk for osteoporosis? A. 40-year-old man who has asthma B. 30-year-old female who jogs daily C. 65-year-old female who smokes cigarettes and is sedentary D. 65-year-old male who drinks alcohol excessively In providing dietary instructions to a client to minimize the risk of osteoporosis, the nurse should recommend which of the following foods? A. Bread B. Yogurt C. Chicken D. Rice OSTEOARTHRITIS KEY POINTS Osteoarthritis (OA) is a disorder characterized by progressive deterioration of the articular cartilage. It is a non-inflammatory (unless localized), nonsystemic disease. It is a process where new tissue is produced as a result of cartilage destruction within the joint. The destruction outweighs the production. The cartilage and bone beneath the cartilage erode and osteophytes (bone spurs) form, resulting in narrowed joint spaces The changes within the joint lead to pain, immobility, muscle spasms, and potential inflammation. RISK FACTORS Age Decreased muscle strength Obesity Possible genetic link Early in the disease process of OA, it may be difficult to distinguish from rheumatoid arthritis (RA). DIAGNOSTIC PROCEDURES AND NURSING INTERVENTIONS ESR and high-sensitivity C-reactive protein may be slightly elevated related to secondary synovitis. X ray can determine structural changes within the joint. CT imaging scan may be used to determine vertebral involvement ASSESSMENT Joint pain and stiffness that resolves with rest or inactivity (chief report) Pain with joint palpation or ROM (observe for muscle atrophy, loss of function, client limp when walking, and restricted activity due to pain) Crepitus in one or more of the affected joints Enlarged joint related to bone hypertrophy Heberden’s nodes enlarged at the distal interphalangeal (DIP) joints Inflammation resulting from secondary synovitis, indicating advanced disease ASSESS/MONITOR Pain: Level (0-10), location, characteristics, quality, and severity Degree of functional limitation Levels of pain and fatigue after activity ROM Proper functional/joint alignment Home barriers Ability to perform activities of daily living (ADLs) NANDA NURSING DIAGNOSES Chronic pain Impaired physical mobility Activity intolerance Self care deficit Disturbed body image NURSING INTERVENTIONS Conservative therapy includes: Balance rest with activity. Use bracing or splints. Apply thermal therapies (heat or cold). Analgesic therapy. Acetaminophen NSAIDS Topical salicylates Glucosamine (rebuilds cartilage) Intra-articular injections of glucocorticoids (treat localized inflammation) NURSING INTERVENTIONS When all other conservative measures fail, the client may choose to undergo joint replacement surgery to relieve the pain and improve mobility and quality of life. Osteotomy; remove damaged cartilage and correct the deformity. Instruct the client on the use of analgesics and NSAIDS prior to activity and around the clock as needed. Balance rest with activity. Instruct the client on proper body mechanics. INTERVENTION Encourage the use of thermal applications: heat to alleviate pain, ice for acute inflammation. Encourage the use of complementary and alternative therapies, including: acupuncture, hypnosis, magnets,……. Encourage the use of splinting for joint protection and the use of larger joints. Encourage the use of assistive devices to promote independence, including an elevated toilet seat, shower bench, ………….. Encourage the use of a daily schedule of activities that will promote independence (high-energy activities in the morning). Encourage a well-balanced diet and ideal body weight. Consult a dietitian to provide meal-planning for balanced nutrition. Rheumatoid Arthritis KEY POINTS RA is a chronic, systemic, progressive inflammatory disease of the synovial tissue. It is a bilateral systemic inflammatory disease process involving multiple joints. In contrast, osteoarthritis is a unilateral degenerative disease process of a single joint. It is classified as an autoimmune process in which antibodies are formed against synovial tissues, including: Synovial membrane. Articular cartilage. Joint capsule. Tendons and ligaments surrounding the joint. Involvement of the spine, particularly the cervical joints. KEY POINTS The natural course of the disease is one of exacerbations and remissions. Inflammation and tissue damage can cause severe deformities that greatly restrict function Risk Factors Female gender Age 20 to 50 years Genetic predisposition Epstein Barr virus Stress DIAGNOSTIC PROCEDURES AND NURSING INTERVENTIONS Rheumatoid Factor (RF) antibody Diagnostic for rheumatoid arthritis = 1:40 to 1:60 (normal ≤ 1:20). High titers correlate with severe disease. Antinuclear Antibody (ANA) Titer (antibody produced against one’s own DNA) A positive ANA titer is associated with RA (normal is negative ANA titer at 1:20 dilution) Erythrocyte Sedimentation Rate (ESR): Elevated 20 to 40 mm/hr = mild inflammation. 40 to 70 mm/hr = moderate inflammation. 70 to 150 mm/hr = severe inflammation Arthrocentesis; Synovial fluid aspiration by needle With RA, increased white blood cells (WBCs) and RF are present. ASSESSMENTS Clinical findings depend on the area affected by the disease process: Pain at rest and with movement Morning stiffness Joint swelling Joint deformity Anorexia/weight loss Fever (generally low grade) Fatigue Muscle weakness/atrophy Assess/Monitor Pain (character, intensity, effectiveness of relief measures) Functional ability Indications of infection NANDA NURSING DIAGNOSES Fatigue Impaired physical mobility Chronic pain Disturbed body image Risk for injury NURSING INTERVENTIONS Apply heat or cold to affected areas as indicated based on client response. Morning stiffness (hot shower) Pain (heated paraffin) Edema (cold therapy) Assist with and encourage physical activity to maintain joint mobility (within the capabilities of the client). Teach the client measures to: Maximize functional activity. Minimize pain. Conserve energy (pacing activities, rest periods) NURSING INTERVENTIONS Provide a safe environment. Facilitate the use of assistive devices. Remove unnecessary equipment/supplies. Utilize progressive muscle relaxation. Monitor the client for signs/symptoms of fatigue. Refer the client to support groups as appropriate. Administer medications as prescribed. Analgesics Anti-inflammatories NSAIDs), such as hydroxychloroquine (Plaquenil), sulfasalazine (Azulfidine) Steroids, such as prednisone Monitor for fluid retention, hypertension, and renal dysfunction. NURSING INTERVENTIONS Immunosuppressants (may slow the progression of disease) Disease-modifying anti-rheumatic medications (DMARM)such as hydroxychloroquine, sulfasalazine, minocycline (slow the progression of joint damage from rheumatoid arthritis. Methotrexate (Rheumatrex) Monitor for toxic effects (bone marrow suppression, increased liver enzymes). NURSING INTERVENTIONS Biological response modifiers: Inhibit the action of tumor necrosis factor (TNF); is a cytokine produced primarily by monocytes and macrophages. It is found in synovial cells and macrophages in the tissues. Do not administer if the client has a serious infection. Monitor for injection/infusion reactions. Monitor CBC and the client for signs of infection. Monitor for medication effectiveness (reduced pain, increased mobility). Teach the client regarding signs/symptoms that need to be reported immediately (fever, infection). COMPLICATIONS AND NURSING IMPLICATIONS Sjogren’s syndrome (dry eyes, dry mouth, dry vagina) Joint deformity (tendon rupture, secondary osteoporosis) Vasculitis (ischemic organs) Cervical subluxation (risk of quadriplegia and respiratory compromise)