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Summer Research Opportunities with FSU College of Medicine Faculty The research opportunities below were submitted by CoM faculty members for dissemination to students interested in applying for the 2017 CoM Summer Research Fellowship. A brief description is included, and additional information about these opportunities can be found on the Medical Student Research website. If you are interested in working with these or any CoM faculty members to apply for the Summer Research Fellowship, you are encouraged to begin reaching out to them. Contact information is included below. Research Opportunity: Dermal Wound Healing in Response to Aging This research study is being conducted by Dr. Michael Blaber at the FSU-COM Main Campus in the Biomedical Sciences Department. The project involves studying dermal wound healing in response to gaining. The study will utilize excisional surgery in mice, and monitoring sex and age-specific differences. Contact: Michael Blaber, PhD Professor, Biomedical Sciences Florida State University College of Medicine Email: [email protected] Phone: 850-644-3361 Research Opportunity: Cancer Research in Daniel Kaplan’s Lab The Kaplan lab has an excellent opportunity for a cancer research investigation. The medical student will be involved in identifying, characterizing, and validating a potential new cancer marker in human cell lines and tissues. Mcm2, a component of the DNA replication apparatus, is established as an excellent marker for numerous cancers, including colorectal cancer, breast cancer, kidney cancer, bladder cancer, mouth, esophagus, lung, and brain cancer. We will be testing the hypothesis that a phosphorylated from of Mcm2, present only during cell division, will be expressed in high levels in cancer cells compared to normal cells. Methods including siRNA, Western Blot and Immunohistochemistry will be used. Contact: Daniel L Kaplan Ph.D. Associate Professor Biomedical Sciences Florida State University College of Medicine 1115 West Call Street Tallahassee, FL 32306-4300 Office: (850) 645-1481, MSR 3350-C Lab: (850) 645-2929, MSR 3310-L [email protected] Research Opportunity: Contribution of Dopamine Receptor Signaling in the Cerebral Cortex to Behavioral Depression This research study is being conducted by Dr. Gregg Stanwood at the FSU-COM Main Campus in the Biomedical Sciences Department. Emerging data has implicated dysregulation of GABAergic interneurons in the frontal cortex to the pathophysiology of depression and mood disorders. This study will use mouse models conferring loss of expression of specific dopamine receptors in specific neuronal subpopulations and examining them behaviorally, cellularly, and molecularly. The study will ascertain the pharmacological and molecular correlates of these responses, and test whether the conditional deletion contributes to enhanced behavioral resilience. Research will increase understanding of how genes and environment work together to influence the development of depression and other mental health disorders, and may reveal novel therapeutic strategies. Contact: Gregg Stanwood, PhD Associate Professor, Biomedical Sciences Florida State University College of Medicine Email: [email protected]