Download List of Publications – Research Group Diederichsen

List of Publications – Research Group Diederichsen
(last update November 2015)
N. J. Pawar, D. D. Dhavale, U. Diederichsen, Multivalent Presentation of Carbohydrates in 314Helical Peptide Templets: Synthesis, Conformatinal analysis and Saccharide Recognition Org.
Biomol. Chem, 2015, DOI: 10.1039/C5OB01673H.
H. Rao, M. S. Damian, A. Alshiekh, S. K. C. Elmroth, U. Diederichsen, Design, synthesis and DNA
interaction of chimera between a platinum complex and an IHF mimicking peptide, Org. Biomol.
Chem, 2015, DOI: 10.1039/C5OB01885D.
S. Kabatas, I.-C. Vreja, S. K. Saka, C. Höschen, K. Kröhnert, F. Opazo, S. O. Rizzoli, U.
Diederichsen, A contamination-insensitive probe for imaging specific biomolecules by secondary ion
mass spectrometry, Chem. Commun., 2015, 51, 13221-13224.
S. Dickgießer, N. Rasche, D. Nasu, S. Middel, S. Hörner, O. Avrutina, U. Diederichsen, H. Kolmar,
Self-assembled hybrid aptamer-Fc conjugates for targeted delivery - a modular chemoenzymatic
approach, ACS Chem. Biol., 2015, 10, 2158–2165.
P. Kumar, S. Guha, U. Diederichsen, SNARE Protein Analogue Mediated Membrane Fusion, J.
Pept. Sci., 2015, 21, 621-629.
C. Nadler, A. Nadler, C. Hansen, U. Diederichsen, A novel photocleavable auxiliary for Extended
Native Chemical Ligation, Eur. J. Org. Chem., 2015, 3095-3102.
I.-C. Vreja, S. Kabatas, S. K. Saka, K. Kröhnert, C. Höschen, F. Opazo, U. Diederichsen, S. O.
Rizzoli, Secondary ion mass spectrometry of genetically-encoded targets, Angew. Chem. 2015, 127,
5876–5880; Angew. Chem. Int. Ed., 2015, 54, 5784–5788.
D. Milovanovic, A. Honigmann, S. Koike, F. Göttfert, G. Pähler, M. Junius, S. Müllar, U.
Diederichsen, A. Janshoff, H. Grübmuller, H. J. Risselada, C. Eggeling, S. W. Hell, G. van den
Bogaart, R. Jahn, Hydrophobic mismatch sorts SNARE proteins into distinct membrane domains,
Nat. Commun., 2015, DOI: 10.1038/ncomms6984.
U. Diederichsen, in Jahrbuch der Akademie der Wissenschaften zu Göttingen 2013, Chemie mit
DNA und Peptiden: von präbiotischer Chemie zu Mechanismen in der Biochemie, De Gruyter, Berlin
2014, 159-167.
U. M. Kotyrba, K. Pröpper, E.-F. Sachs, A. Myanovska, T. Joppe, F. Lissy, H. Laatsch, G. M.
Sheldrick, K. Koszinowski, U. Diederichsen, Triostin A derived cyclopeptide as architectural template
for the alignment of four recognition units, ChemistryOpen, 2014, 3, 152-160.
N. J. Pawar, N. S. Sidhu, G. M. Sheldrick, D. D. Dhavale, U. Diederichsen, Molecular architecture
with carbohydrate functionalized β-peptides adopting 314-helical conformation, Beilstein J. Org.
Chem. 2014, 10, 948-955.
D. Matthesa, V. Daebel, K. Meyenberg, D. Riedel, G. Heim, U. Diederichsen, A. Lange, B. L. de
Groot, Spontaneous aggregation of the insulin-derived steric zipper peptide VEALYL results in
different aggregation forms with common features, J. Mol. Biol. 2014, 426, 362-376.
S. Guha, J. Graf, B. Göricke, U. Diederichsen, Nucleobase caged peptide nucleic acids: PNA/PNA
duplex destabilization and light triggered PNA/PNA recognition, J. Pept. Sci., 2013, 19, 415-422.
T. Hotz , O. Schütte, H. Sieling , T. Polupanow, U. Diederichsen, C. Steinem, A. Munk, Idealizing ion
channel recordings by jump segmentation and statistical multiresolution analysis, IEEE Trans on
NanoBioScience, 2013, 12, 376-386.
A. Honigmann, G. van den Bogaart, E. Iraheta, H. J. Risselada, D. Milovanovic, V. Müller, S. Müllar,
U. Diederichsen, D. Fasshauer, H. Grubmüller, S. W. Hell, C. Eggeling, K. Kühnel, R. Jahn,
Phosphatidylinositol 4,5-bisphosphate clusters act as molecular beacons for vesicle recruitment,
Nat. Struct. Mol. Biol., 2013, 20, 679-686.
I. Tkach, S. Pornsuwan, C. Höbartner, F. Wachowius, S. Th. Sigurdsson, T. Y. Baranova, U.
Diederichsen, G. Sicoli, M. Bennati, Orientation selection in distance measurements between
nitroxide spin labels at 94 GHz EPR with variable dual frequency irradiation, Phys. Chem. Chem.
Phys., 2013, 15, 3433-3437.
G. Portella, T. Polupanow, F. Zocher, D. A. Boytsov, P. Pohl, U. Diederichsen, B. L. de Groot,
Design of Peptide-Membrane Interactions to Modulate Single-File Water Transport through Modified
Gramicidin Channels, Biophysical Journal, 2012 , 103, 1698-1705.
G. Pähler, C. Panse, U. Diederichsen, A. Janshoff, Coiled-Coil Formation on Lipid Bilayers—
Implications for Docking and Fusion Efficiency, Biophysical Journal, 2012, 103, 2295-2303.
J. A. Cuesta-Seijo, J. Zhang, U. Diederichsen, G. M. Sheldrick, Continuous β-turn fold of an
alternating alanyl/homoalanyl peptide nucleic acid', Acta Crystallogr. 2012, D68, 1067-1070.
G. van den Bogaart, K. Meyenberg, U. Diederichsen, R. Jahn, Phosphatidylinositol 4,5bisphosphate increases the Ca2+ affinity of synaptotagmin-1 40-fold, J. Biol. Chem.2012, 287,
16447-16453.
F. Stein, T. Mehmood, T. Plass, J. H. Zaidi, U. Diederichsen, Synthesis of trifunctional cyclo-ßtripeptide templates, Beilstein J. Org. Chem., 2012, 8, 1576-1583.
S. Scholz, E. K. Liebler, B. Eickmann, H.-J. Fritz, U. Diederichsen, Variation of the intercalating
proline in artificial peptides mimicking the DNA binding and bending IHF protein,
Amino Acids, 2012, 43, 289-298.
B. Holzberger, J. Strohmeier, V. Siegmund, U. Diederichsen, A. Marx, Enzymatic synthesis of 8vinyl- and 8-styryl-2'-deoxyguanosine modified DNA - novel fluorescent molecular probes,
Bioorg. Med. Chem. Lett., 2012, 22, 3136-3139.
S. Müllar, J. Strohmeier, U. Diederichsen, 8-Vinylguanine nucleo amino acid - a fluorescent PNA
building block, Org. Lett. 2012, 14, 1382-1385.
F. Fehr, A. Nadler, F. Brodhun, I. Feussner, U. Diederichsen, Semi-Synthesis and Analysis of
chemically modified Zif268 Zinc Finger Domains, ChemistryOpen, 2012, 1, 26-32.
U. Diederichsen, in 'Aus den Elfenbeintürmen der Wissenschaft, XLAB Science Festival', E.-M.
Neher (Ed.), Band 5, 'Lineare molekulare Architekturen mit DNA- und Peptid-Biooligomer-Gerüsten',
Wallstein Verlag, Göttingen 2011, 111-123.
G. van den Bogaart, K. Meyenberg, H. J. Risselada, H. Amin, K. I. Willig, B. E. Hubrich, M. Dier, S.
W. Hell, H. Grubmüller, U. Diederichsen, R. Jahn, Membrane protein sequestering by ionic-protein
lipid interactions, Nature, 2011, 479, 552-555.
S. Stoller, G. Sicoli, T. Y. Baranova, M. Bennati, U. Diederichsen, TOPP – A Novel Nitroxide-labeled
Amino Acid for EPR Distance Measurements, Angew. Chem., 2011, 123, 9917-9920., Angew.
Chem. Int. Ed., 2011, 50, 9743-9746.
A. S. Lygina, K. Meyenberg, R. Jahn, U. Diederichsen, Transmembrane Domain Peptide/Peptide
Nucleic Acid Hybrid as a Model of a SNARE Protein in Vesicle Fusion, Angew. Chem., 2011, 123,
8756-8760., Angew. Chem. Int. Ed., 2011, 50, 8597-8601.
K. Meyenberg, A. S. Lygina, G. van den Bogaart, R. Jahn, U. Diederichsen, SNARE derived peptide
mimic inducing membrane fusion, Chem. Comm., 2011, 47 (33), 9405-9407.
K. E. Otto, S. Hesse, T. N. Wassermann, C. A. Rice, M. A. Suhm, T. Stafforst, U. Diederichsen,
Temperature-dependent intensity anomalies in amino acid esters: weak hydrogen bonds in
protected glycine, alanine and valine, PhysChemChemPhys, 2011, 13, 14019-14025.
J. Strohmeier, I. Hertel, U. Diederichsen, M. G. Rudolph, D. Klostermeier, Changing nucleotide
specificity of the DEAD-box helicase Hera abrogates communication between the Q-motif and the Ploop, Biol. Chem., 2011, 392, 357-369.
A. Nadler, J. Strohmeier, U. Diederichsen,
8-Vinyl-2’-deoxyguanosine as Fluorescent 2’Deoxyguanosine Mimic for Investigating DNA Hybridization and Topology, Angew. Chem., 2011,
123, 5504-5508. online, Angew. Chem. Int. Ed., 2011, 50, 5392-5396. online
S. Scholz, E. K. Liebler, B. Eickmann, H.-J. Fritz, U. Diederichsen, Variation of the intercalating
proline in artificial peptides mimicking the DNA binding and bending IHF protein, Amino Acids, 2011,
accepted.
G. v. d. Bogaart, S. Thutupalli, J. H. Risselada, K. Meyenberg, M. Holt, D. Riedel, U. Diederichsen,
S. Herminghaus, H. Grubmüller, R. Jahn, Synaptotagmin-1 may be a distance regulator acting
upstream of SNARE nucleation, Nature Struct. Mol. Biol., 2011, 18, 805-812.
A. Nadler, C. Koch, F. Brodhun, J.-D. Wehland, K. Tittmann, I. Feussner, U. Diederichsen, Influence
of substrate dideuteration on the reaction of the bifunctional heme enzyme psi factor producing
oxygenase A (PpoA), ChemBioChem, 2011, 12, 728-737.
P. E. Schneggenburger, A. Beerlink, B. Weinhausen, T. Salditt, U. Diederichsen, Peptide Model
Helices in Lipid Membranes – Insertion, Positioning and Lipid Response on Aggregation Studied by
X-Ray Scattering, Eur. Biophys. J., 2011, 40, 417-436.
E.-F. Sachs, A. Nadler, U. Diederichsen, Triostin A derived hybrid for simultaneous DNA binding and
metal coordination, Amino Acids, 2010, 41, 449-456.
M. S. Damian, H. K. Hedman, S. K. C. Elmroth, U. Diederichsen, Synthesis and DNA Interaction of
Platinum Complex/Peptide Chimera as Potential Drug Candidates, Eur. J. Org. Chem., 2010, 61616170.
J. Strohmeier, A. Nadler, D. Heinrich, A. Fitzner, U. Diederichsen, Synthesis of 8,1’-etheno and 8,2’ethano bridged guanosine derivatives using radical cyclization, Heterocycles, 2010, 82, 713-728.
P. E. Schneggenburger, S. Müllar, B. Worbs, C. Steinem, U. Diederichsen, Molecular Recognition at
the Membrane-Water Interface: Controlling Integral Peptide Helices by Off-Membrane Nucleobase
Pairing, J. Am. Chem. Soc., 2010, 132, 8020-8028.
G. N. Roviello, S. Gröschel, C. Pedone, U. Diederichsen, Synthesis of novel MMT/acyl-protected
nucleo alanine monomers for the preparation of DNA/alanyl-PNA chimeras, Amino Acids, 2010, 38,
1301-1309.
C. P. Sommerhoff, O. Avrutina, H.-U. Schmoldt, D. Gabrijelcic-Geiger, U. Diederichsen and H.
Kolmar, Engineered Cystine Knot Miniproteins as Potent Inhibitors of Human Mast Cell Tryptase
beta, J. Mol. Biol., 2010, 395, 167-195.
P. E. Schneggenburger, B. Worbs, U. Diederichsen, Azide reduction during peptide cleavage from
solid support - the choice of thioscavenger?, J. Pept. Sci., 2010, 16, 10-14.
C. Kleimann, A. Sischka, A. Spiering, K. Tönsing, N. Sewald, U. Diederichsen, D. Anselmetti,
Binding kinetics of bisintercalator Triostin A with optical tweezers force mechanistics, Biophys. J.,
2009, 97, 2780-2784.
A. Kumar Ray, U. Diederichsen, Syntheses of Triostin A Antibiotic and Nucleobase-Functionalized
Analogs as New DNA Binders, Eur. J. Org. Chem., 2009, 4801-4809.
R. Srivastava, A. Kumar Ray, U. Diederichsen, Higher Aggregation of ß-Peptide Networks
Controlled by Nucleobase Pairing, Eur. J. Org. Chem., 2009, 4793-4800.
O. Avrutina, M. Empting, S. Fabritz, M. Daneschdar, H. Frauendorf, U. Diederichsen, H. Kolmar,
Application of copper(I) catalyzed azide-alkyne [3+2] cycloaddition to the synthesis of templateassembled multivalent peptide conjugates, Org. Biomol. Chem., 2009, 7, 4177-4185.
U. Diederichsen, Dynamic Sequence Modification: A Design Principle for Synthetic Informational
Oligomers, ChemBioChem, 2009, 10, 2717-2719.
A. Nadler, C. Hain, U. Diederichsen, Histidine Analog Amino Acids Providing Metal-Binding Sites
Derived from Bioinorganic Model Systems, Eur. J. Org. Chem., 2009, 4593-4599.
P. E. Schneggenburger, A. Beerlink, B. Worbs, T. Salditt, U. Diederichsen, A Novel Heavy Atom
Label for Side Specific Peptide Iodination – Synthesis, Membrane Incorporation and X-ray
Reflectivity, ChemPhysChem, 2009, 10, 1567-1576.
D. Heinrich, U. Diederichsen, M. G. Rudolph, Lys314 is a nucleophile in non-classical reactions of
Orotidine-5'-Monophosphate Decarboxylase, Chem. Eur. J. 2009, 15, 6619-6625.
N. Diezemann, L. M. M. Weigang, P. Chakraborty, H. Frauendorf, T. Letzel, U. Diederichsen,
Organization of Nucleobase Functionalized ß-Peptides Investigated by Soft Electrospray Ionization
Mass Spectrometry, J. Mass. Spectrom. 2009, 44, 794-802.
A. Heitz, O. Avrutina, D.-L. Nguyen, U. Diederichsen, J.-F. Hernandez, J. Gracy, H. Kolmar, L.
Chiche, Knottin cyclization: Impact on Structure and Dynamics, BMC Structural Biology, 2008, 8:54.
J. Wittmann, D. Heinrich, U. Diederichsen, M. G. Rudolph, 1094-Pos Crystal Structures of Human
Orotidine-5’-monophosphate Decarboxylase – Implications for Drug Design and Catalysis, Biophys.
J., 2008, 94, 368-371.
M. Pitulescu, M. Grapp, R. Krätzner, W. Knepel, U. Diederichsen, Synthesis of formacetal linked
dinucleotides to facilitate dsDNA bending and binding to the homeodomain of Pax6, Eur. J. Org.
Chem., 2008, 2100-2106.
A. Nadler, U. Diederichsen, Guanosine analog with respect to Z-DNA stabilization: Nucleotide with
combined C8-bromine and C2'-arabino ethynyl modifications, Eur. J. Org. Chem., 2008, 1544-1549.
A. Fitzner, H. Frauendorf, H. Laatsch, U. Diederichsen, Formation of gutingimycin: analytical
investigation of trioxacarcin A mediated alkylation of dsDNA, Anal. Bioanal. Chem., 2008, 390,
1139-1147.
O. Avrutina, H.-U. Schmoldt, D. Gabrijelcic-Geiger, A. Wentzel, H. Frauendorf, C. P. Sommerhoff, U.
Diederichsen, H. Kolmar, Head-to-tail cyclized cystine-knot peptides by a combined recombinant
and chemical route of synthesis, ChemBioChem, 2008, 9, 33-37.
J. Wittmann, D. Heinrich, K. Gasow, A. Frey, U. Diederichsen, M. G. Rudolph, Structures of the
human orotidine-5'-monophosphate decarboxlase support a covalent mechanism and provide a
framework for drug design, Structure, 2008, 16, 82-92.
D. Heinrich, T. Wagner, U. Diederichsen, Synthesis and DNA Incorporation of an Ethynyl-Bridged
Cytosine C-Nucleoside as Guanosine, Org. Lett., 2007, 9, 5311-5314.
L. F. Tietze, T. Eicher, U. Diederichsen, A. Speicher, Reactions and Syntheses in the Organic
Chemistry Laboratory, Wiley-VCH, Weinheim, September 2007.
A. Küsel, Z. Khattari, P. E. Schneggenburger, A. Banerjee, T. Salditt, U. Diederichsen, Conformation
and interaction of a D,L-alternating peptide with bilayer membrane: X-ray reflectivity, CD and FTIR
spectroscopy, ChemPhysChem, 2007, 8, 2336-2343.
A. Weiß, U. Diederichsen, Uniformly nucleobase functionalized β-peptide helices: Watson-Crick
pairing of non-specific aggregation, Eur. J. Org. Chem., 2007, 5531-5539.
N. Hildebrandt, U. Diederichsen, Superparamagnetic iron oxide nanoparticles functionalized with
peptides by electrostatic interactions, ARKIVOC; 2007; 5, 79-90.
T. Stafforst, U. Diederichsen, Synthesis of the Green Fluorescent Protein chromophore as alaninyl
and N-(2-aminoethyl)glycinyl amino acid side chain for incorporation into peptides and peptide
nucleic acids, Eur. J. Org. Chem., 2007, 899-911.
T. Stafforst, U. Diederichsen, Solid-phase synthesis of acid-sensitive N-(2-aminoethyl)glycine-PNA
oligomers via Fmoc/Bhoc-strategy, Eur. J. Org. Chem., 2007, 681-688.
T. Stafforst, U. Diederichsen, Thymine Oxetanes as Charge Traps for Chemical Monitoring of
Nucleic Acid Mediated Transfer of Excess Electrons, Angew. Chem., 2006, 118, 5502-5506; Angew.
Chem. Int. Ed., 2006, 45, 5376-5380.
P. Chakraborty, A. M. Brückner, U. Diederichsen, Synthesis of a 7-Deazaguanine-Functionalized βAmino Acid: Improved Specificity of ß-Peptide Helix Organization, Eur. J. Org. Chem., 2006, 24102416.
O. Avrutina, H.-U. Schmoldt, D. Gabrijelcic-Geiger, D. Le Nguyen, C. P. Sommerhoff, U.
Diederichsen, H. Kolmar, Trypsin inhibition by macrocyclic and open-chain variants of the squash
inhibitor MCoTI-II, Biol. Chem., 2005, 386, 1301-1306.
A. Küsel, J. Zhang, M. Alvarino Gil, C. A. Stückl, W. Meyer-Klaucke, F. Meyer, U. Diederichsen,
Metal binding within a peptide-based nucleobase stack with tuneable double strand topology, Eur. J.
Inorg. Chem. 2005, 4317-4324.
T. Stafforst, U. Diederichsen, (6-4)-Photolyase activity requires charge shift reaction, Chem.
Commun., 2005, 3430-3432.
P. Chakraborty, U. Diederichsen, Three Dimensional Organization of Helices: Design Principles for
Nucleobase-Functionalized β-Peptides, Chem. Eur. J. 2005, 11, 3207-3216.
B. Abel, A. Charvat, U. Diederichsen, M. Faubel, B. Girmann, J. Niemeyer, A. Zeeck, Applications,
features, and mechanistic aspects of liquid water beam desorption mass spectrometry,
Int. J. Mass Spectr. 2005, 243, 177-188.
U. Diederichsen, D. Weicherding, N. Diezemann, Side chain homologation of alanyl peptide nucleic
acids: pairing selectivity and stacking, Org. Biomol. Chem. 2005, 3, 1058-1066.
B. Dietrich, U. Diederichsen, Synthesis of Cyclopeptidic Analogues of Triostin A with Quinoxalines or
Nucleobases as Chromophores, Eur. J. Org. Chem. 2005, 147-153.
O. Avrutina, H.-U. Schmoldt, H. Kolmar, U. Diederichsen, Fmoc-Assisted Synthesis of a 29-Residue
Cystine-Knot Trypsin Inhibitor Containing a Guaninyl Amino Acid at the P1-Position, Eur. J. Org.
Chem. 2004, 4931-4935.
E. Alexopoulos, A. Küsel, G. M. Sheldrick, U. Diederichsen, I. Usón, Solution and structure of an
alternating D,L-peptide, Acta Cryst. 2004, D60, 1971-1980.
E. K. Liebler, U. Diederichsen, From the IHF Protein to Design and Synthesis of a SequenceSpecific DNA Bending Peptide, Org. Lett. 2004, 6, 2893-2896.
K. B. Lorenz, U. Diederichsen, A Solution-Phase Synthesis of Nucleobase-Substituted Analogues of
Triostin A, J. Org. Chem. 2004, 69, 3917-3927.
D. Weicherding, W. B. Davis, S. Hess, T. von Feilitzsch, M. E. Michel-Beyerle, U. Diederichsen,
Femtosecond Time-resolved Guanine Oxidation in Acridine Modified Alanyl Peptide Nucleic Acids,
Bioorg. Med. Chem. Lett. 2004, 14, 1629-1632.
K. B. Lorenz, U. Diederichsen, Nucleo Amino Acids as Arginine Mimetics in Cyclic Peptide Hybrids,
Letters in Peptide Science 2003, 10, 111-117.
A. M. Brückner, P. Chakraborty, S. H. Gellman, U. Diederichsen, Molecular Architecture with
Functionalized ß-Peptide Helices, Angew. Chem. 2003, 115, 4532-4536; Angew. Chem. Int. Ed.
2003, 42, 4395-4399.
A. M. Brückner, M. Garcia, A. Marsh, S. H. Gellman, U. Diederichsen, Synthesis of Novel Nucleo-ßAmino Acids and Nucleobase-Functionalized ß-Peptides, Eur. J. Org. Chem. 2003, 3555-3561.
T. Wagner, W. B. Davis, K. B. Lorenz, M. E. Michel-Beyerle, U. Diederichsen, Synthesis of Amino
Acids with Unnatural Nucleobases or Chromophores Suitable for Use in Model Electron-Transfer
Studies, Eur. J. Org. Chem. 2003, 3673-3679.
U. Diederichsen, Fluorous Techniques: Progress in Reaction-Processing and Purification, in
"Organic Synthesis- Highlights V" Hrsg. H.-G. Schmalz, T.Wirth, Wiley-VCH, Weinheim 2003, 93104.
U. Diederichsen, Bryostatin and their Analogues, in "Organic Synthesis- Highlights V" Hrsg. H.-G.
Schmalz, T.Wirth, Wiley-VCH, Weinheim 2003, 307-316.
U. Diederichsen, Eleutherobin: Synthesis, Structure/Activity Relationship, and Pharmacophore, in
"Organic Synthesis- Highlights V" Hrsg. H.-G. Schmalz, T.Wirth, Wiley-VCH, Weinheim 2003, 317325.
U. Diederichsen, K. B. Lorenz, Total Synthesis of the Natural Products CP-263, 114 and CP-225,
917, in "Organic Synthesis- Highlights V" Hrsg. H.-G. Schmalz, T.Wirth, Wiley-VCH, Weinheim
2003, 326-341.
U. Diederichsen, T. Wagner, Solid-Phase Synthesis of Oligosaccharides, in "Organic SynthesisHighlights V" Hrsg. H.-G. Schmalz, T.Wirth, Wiley-VCH, Weinheim 2003, 384-394.
Arndt M. Brückner, Harald W. Schmitt, Ulf Diederichsen, Nucleo-ß-Amino Acids: Synthesis and
Oligomerization to ß-Homoalanyl-PNA, Helv. Chim. Acta 2002, 85, 3855-3866.
M. F. H. Hoffmann, A. M. Brückner, T. Hupp, B. Engels, U. Diederichsen, Specific Purine-Purine
Base Pairing in Linear Alanyl Peptide Nucleic Acids, Helv. Chim. Acta 2000, 83, 2580-2593.
U. Diederichsen, C. Biro, Phe and Asn Side Chains in DNA Double Strands, Bioorg. Med. Chem.
Lett. 2000, 10, 1417-1420.
U. Diederichsen, D. Weicherding, Interactions of Amino Acid Side Chains with Nucleobases in
Alanyl-PNA, Synlett 1999, S1, 917-920.
U. Diederichsen, Bryostatine und ihre Analoga, Nachr. Chem. Tech. Lab. 1999, 47, 432-438.
U. Diederichsen, Oligosaccharid Festphasensynthese, Nachr. Chem. Tech. Lab. 1999, 47, 673-676.
U. Diederichsen, Chemie mit Fluorphasen: Vorteile für Reaktionsführung und Aufarbeitung, Nachr.
Chem. Tech. Lab. 1999, 47, 805-809.
U. Diederichsen, Synthese, Struktur-Aktivitäts-Beziehung Pharmakophor von Eleutherobin, Nachr.
Chem. Tech. Lab. 1999, 47, 1228-1233.
U. Diederichsen, Totalsynthese der Naturstoffe CP-263,114 und CP 225,917, Nachr. Chem. Tech.
Lab. 1999, 47, 1423-1427.
U. Diederichsen, T. Lindhorst, L. A. Wessjohann, B. Westermann, Bioorganic Chemistry - Highlights
and New Aspects, Hrsg. Wiley-VCH, Weinheim 1999, 255-261.
U. Diederichsen, T. Lindhorst, L. A. Wessjohann, B. Westermann, Alanyl-PNA: A Model System for
DNA Using a Linear Peptide Backbone as Scaffold, U. Diederichsen, in "Bioorganic Chemistry Highlights and New Aspects" Hrsg. Wiley-VCH, Weinheim 1999, 255-261.
U. Diederichsen, Nucleinsäure-Analoga und neuartige Peptidstrukturen, Trendberichte Organische
Chemie 1998, Nachr. Chem. Tech. Lab. 1999, 47, 171-175.
U. Diederichsen, Oligomers with Intercalating Cytosine-Cytosine+ Base Pairs and Peptide
Backbone: DNA i-Motif Analogues, Angew. Chem. 1998, 110, 2395-2397; Angew. Chem. Int. Ed.
1998, 37, 2273-2276.
U. Diederichsen, Selectivity of DNA Replication: The Importance of Base-Pairs Geometry over
Hydrogen Bonding, Angew. Chem. 1998, 110, 1745-1747; Angew. Chem. Int. Ed. 1998, 37, 16551657.
U. Diederichsen, H. W. Schmitt, ß-Homoalanyl-PNA: A Special Case of ß-Peptides with ß-SheetLike Backbone Conformation; Organization in Higher Ordered Structures, Eur. J. Org. Chem. 1998,
827-835.
U. Diederichsen, Alanyl-PNA Homoduplex: A-T Pairing with the N7-Regioisomer of Adenine, Bioorg.
Med. Chem. Lett. 1998, 8, 165-168.
U. Diederichsen, H. W. Schmitt, ß-Homoalanyl-PNA: Synthesis and Indication of Higher Ordered
Structures, Angew. Chem. 1998, 110, 312-315; Angew. Chem. Int. Ed. 1998, 37, 302-305.
K. Groebke, J. Hunziker, W. Fraser, L. Peng, U. Diederichsen, K. Zimmermann, A. Holzner, C.
Leumann, A. Eschenmoser, Warum Pentose- und nicht Hexose-Nucleinsäuren? Teil V: (PurinPurin-Basenpaarung in der Homo-DNS-Reihe: Guanin, Isoguanin, 2,6-Diaminopurin und Xanthin),
Helv. Chim. Acta 1998, 81, 375 - 474.
U. Diederichsen, Alanyl-PNA: Evidence for Linear Band Structures Based on Guanine-Cytosine
Base Pairs, Angew. Chem. 1997, 109, 1966-1969; Angew. Chem. Int. Ed. Engl. 1997, 36, 18861889.
U. Diederichsen, Alanyl-PNA Oligomers: A New System for Intercalation, Bioorg. Med. Chem. Lett.
1997, 7, 1743-1746.
D. P. Curran, U. Diederichsen, M. Palowich, Radical Cyclizations of Acylgermanes. New Reagent
Equivalents of the Carbonyl Radical Acceptor Synthon, J. Am. Chem. Soc. 1997, 119, 4797-4804.
U. Diederichsen, D. P. Curran, Biomolecular Reactions of Alkyl Halides and Acylgermanes:
Formation of Ketones, Diketons, and other Products by Radical-Radical Reaction, J. Organomet.
Chem. 1997, 531, 9-12.
U. Diederichsen, H. W. Schmitt, Self-Pairing PNA with Alternating Alanyl-/Homoalanyl Backbone,
Tetrahedron Lett. 1996, 37, 475-478.
U. Diederichsen, Pairing Properties of Alanyl Peptide Nucleic Acids Containing an Amino Acid
Backbone with Alternating Configuration, Angew. Chem. 1996, 108, 458-461; Angew. Chem. Int. Ed.
Engl. 1996, 35, 445-448.
U. Diederichsen, A. Hypoxanthin-Basenpaarungen in HOMO-DNA-Oligonucleotiden B. Zur Frage
des Paarungsverhaltens von Glucopyranosyl-Oligonucleotiden, Dissertation ETH Nr. 10122, Zürich
1993.
J. Hunziker, H.-J. Roth, M. Böhringer, A. Giger, U. Diederichsen, M. Göbel, R. Krishnan, B. Jaun, C.
Leumann, A. Eschenmoser, Warum Pentose- und nicht Hexose-Nucleinsäuren? Teil III: Oligo(2’,3’dideoxy-b-D-glucopyranosyl)nucleotide ("HOMO-DNS"): Paarungseigenschaften, Helv. Chim. Acta
1993, 76, 259 - 352.
Prof. Dr. U. Diederichsen
Institut für Organische und
Biomolekulare Chemie
Georg-August-Universität Göttingen
Tammannstr. 2
37077 Göttingen
- Germany -
Phone: +49 (0)551-39 3221
Fax: +49 (0)551-39 22944
Email: [email protected]
http://www.diederichsen.chemie.uni-goettingen.de/